Drosophila melanogaster

93 known processes

CrebA (Dmel_CG7450)

Cyclic-AMP response element binding protein A

(Aliases: BcDNA:SD05937,CG7450,creb,l(3)03576,CRE-BP,CREB-a,Creb A,BOX B Binding Factor-2,CREB-A,BBF-2,BBF2_DROME,Bbbf2,dCrebA,dCREBA,Creb-A,CREB,dCREB-A,dCreb-A,Creb,crebA,Dmel\CG7450)

CrebA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.768
appendage morphogenesis GO:0035107 397 0.754
imaginal disc derived appendage development GO:0048737 399 0.663
appendage development GO:0048736 401 0.612
compound eye development GO:0048749 307 0.574
wing disc morphogenesis GO:0007472 344 0.498
embryo development ending in birth or egg hatching GO:0009792 152 0.485
eye development GO:0001654 323 0.457
photoreceptor cell differentiation GO:0046530 170 0.453
morphogenesis of an epithelium GO:0002009 276 0.430
embryonic morphogenesis GO:0048598 206 0.381
compound eye photoreceptor cell differentiation GO:0001751 140 0.371
post embryonic appendage morphogenesis GO:0035120 385 0.364
larval development GO:0002164 104 0.337
muscle structure development GO:0061061 224 0.326
compound eye photoreceptor development GO:0042051 78 0.318
sensory perception GO:0007600 196 0.318
eye morphogenesis GO:0048592 260 0.258
imaginal disc derived wing morphogenesis GO:0007476 337 0.255
lateral inhibition GO:0046331 206 0.242
respiratory system development GO:0060541 213 0.242
compound eye morphogenesis GO:0001745 249 0.241
regionalization GO:0003002 416 0.237
cytoplasmic transport GO:0016482 130 0.217
Mouse
tissue morphogenesis GO:0048729 297 0.214
epithelial cell development GO:0002064 274 0.205
regulation of cell differentiation GO:0045595 302 0.203
cuticle development GO:0042335 86 0.198
tube development GO:0035295 244 0.188
epithelial cell differentiation GO:0030855 322 0.185
establishment or maintenance of cell polarity GO:0007163 167 0.172
regulation of r7 cell differentiation GO:0045676 15 0.164
neurological system process GO:0050877 358 0.162
skin development GO:0043588 65 0.150
eye photoreceptor cell development GO:0042462 81 0.148
molting cycle GO:0042303 56 0.138
body morphogenesis GO:0010171 2 0.138
macromolecular complex assembly GO:0065003 256 0.135
positive regulation of developmental process GO:0051094 143 0.131
sensory organ morphogenesis GO:0090596 260 0.129
muscle cell differentiation GO:0042692 103 0.119
apposition of dorsal and ventral imaginal disc derived wing surfaces GO:0007475 15 0.115
protein localization GO:0008104 284 0.113
establishment of tissue polarity GO:0007164 87 0.111
vesicle mediated transport GO:0016192 381 0.108
Mouse
male gamete generation GO:0048232 201 0.107
cell proliferation GO:0008283 299 0.105
axon development GO:0061564 297 0.105
endocytosis GO:0006897 310 0.104
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.097
single organism intracellular transport GO:1902582 207 0.097
Mouse
negative regulation of gene expression GO:0010629 387 0.095
retina development in camera type eye GO:0060041 4 0.094
reproductive structure development GO:0048608 74 0.093
forebrain development GO:0030900 2 0.092
regulation of neurogenesis GO:0050767 158 0.091
positive regulation of macromolecule metabolic process GO:0010604 405 0.088
embryonic development via the syncytial blastoderm GO:0001700 148 0.085
digestive system development GO:0055123 149 0.083
cell recognition GO:0008037 102 0.082
positive regulation of cell differentiation GO:0045597 64 0.082
establishment of localization in cell GO:0051649 402 0.082
Mouse
head development GO:0060322 135 0.081
regulation of photoreceptor cell differentiation GO:0046532 34 0.080
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.079
ras protein signal transduction GO:0007265 88 0.077
eggshell chorion assembly GO:0007306 66 0.075
morphogenesis of embryonic epithelium GO:0016331 94 0.075
regulation of growth GO:0040008 233 0.075
eye photoreceptor cell differentiation GO:0001754 145 0.074
neuron projection guidance GO:0097485 241 0.074
taxis GO:0042330 304 0.073
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.072
morphogenesis of a polarized epithelium GO:0001738 93 0.071
intracellular transport GO:0046907 228 0.069
Mouse
wing disc pattern formation GO:0035222 66 0.069
axonogenesis GO:0007409 290 0.069
protein complex assembly GO:0006461 200 0.067
small gtpase mediated signal transduction GO:0007264 88 0.066
cellular protein modification process GO:0006464 438 0.065
phagocytosis GO:0006909 215 0.065
protein complex biogenesis GO:0070271 201 0.063
segment specification GO:0007379 33 0.063
positive regulation of gene expression GO:0010628 290 0.062
positive regulation of epithelial cell differentiation GO:0030858 1 0.061
digestive tract development GO:0048565 149 0.061
golgi to plasma membrane transport GO:0006893 8 0.061
positive regulation of rna biosynthetic process GO:1902680 266 0.060
dendrite morphogenesis GO:0048813 199 0.060
death GO:0016265 284 0.058
establishment of ommatidial planar polarity GO:0042067 49 0.058
posttranscriptional regulation of gene expression GO:0010608 145 0.058
organ growth GO:0035265 56 0.055
chromosome organization GO:0051276 360 0.053
hindbrain development GO:0030902 2 0.053
regulation of phosphorylation GO:0042325 147 0.053
photoreceptor cell development GO:0042461 96 0.052
sex differentiation GO:0007548 81 0.051
equator specification GO:0045317 4 0.050
regulation of phosphate metabolic process GO:0019220 210 0.050
camera type eye development GO:0043010 4 0.049
positive regulation of rna metabolic process GO:0051254 271 0.048
regulation of anatomical structure morphogenesis GO:0022603 242 0.047
embryonic organ development GO:0048568 50 0.046
skeletal muscle organ development GO:0060538 48 0.046
chitin based cuticle development GO:0040003 49 0.045
positive regulation of nucleic acid templated transcription GO:1903508 266 0.045
regulation of transport GO:0051049 181 0.045
gland development GO:0048732 191 0.045
musculoskeletal movement GO:0050881 3 0.044
cell death GO:0008219 279 0.044
regulation of epithelial cell differentiation GO:0030856 4 0.044
organic substance transport GO:0071702 257 0.043
molting cycle chitin based cuticle GO:0007591 56 0.043
eye antennal disc development GO:0035214 60 0.042
spermatogenesis GO:0007283 200 0.042
telencephalon development GO:0021537 2 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.041
dorsal ventral pattern formation GO:0009953 133 0.041
muscle attachment GO:0016203 36 0.040
central nervous system development GO:0007417 201 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.039
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.039
head involution GO:0008258 35 0.038
meiotic cell cycle process GO:1903046 132 0.037
heart contraction GO:0060047 26 0.037
growth GO:0040007 359 0.037
cellular component assembly involved in morphogenesis GO:0010927 151 0.037
regulation of small gtpase mediated signal transduction GO:0051056 93 0.036
dna packaging GO:0006323 91 0.036
immune effector process GO:0002252 98 0.035
positive regulation of transcription dna templated GO:0045893 266 0.035
reproductive system development GO:0061458 74 0.035
chromatin organization GO:0006325 207 0.035
regulation of wnt signaling pathway GO:0030111 68 0.034
positive regulation of response to stimulus GO:0048584 323 0.033
imaginal disc pattern formation GO:0007447 91 0.033
negative regulation of cellular metabolic process GO:0031324 382 0.033
dorsal closure GO:0007391 79 0.033
columnar cuboidal epithelial cell development GO:0002066 249 0.032
transcription from rna polymerase ii promoter GO:0006366 368 0.032
regulation of localization GO:0032879 275 0.031
instar larval development GO:0002168 55 0.031
open tracheal system development GO:0007424 204 0.031
chemotaxis GO:0006935 249 0.031
regulation of cellular protein metabolic process GO:0032268 243 0.031
protein modification process GO:0036211 438 0.031
regulation of epithelial cell proliferation GO:0050678 4 0.031
chorion containing eggshell formation GO:0007304 105 0.030
negative regulation of nervous system development GO:0051961 92 0.030
mesodermal cell migration GO:0008078 7 0.030
ovarian follicle cell development GO:0030707 248 0.030
cellular response to nitrogen compound GO:1901699 51 0.030
gland morphogenesis GO:0022612 145 0.030
regulation of protein modification process GO:0031399 112 0.030
establishment of protein localization to organelle GO:0072594 62 0.030
r7 cell differentiation GO:0045466 43 0.030
convergent extension GO:0060026 2 0.029
single organism cellular localization GO:1902580 180 0.029
negative regulation of rna metabolic process GO:0051253 251 0.029
positive regulation of biosynthetic process GO:0009891 316 0.028
axonal fasciculation GO:0007413 12 0.028
neural retina development GO:0003407 4 0.027
compound eye photoreceptor fate commitment GO:0001752 36 0.027
regulation of cell development GO:0060284 215 0.027
developmental programmed cell death GO:0010623 138 0.027
cell junction organization GO:0034330 57 0.027
renal system development GO:0072001 72 0.027
catabolic process GO:0009056 409 0.027
ameboidal type cell migration GO:0001667 151 0.026
cell cell signaling involved in cell fate commitment GO:0045168 210 0.026
organic substance catabolic process GO:1901575 308 0.026
axon guidance GO:0007411 233 0.026
programmed cell death GO:0012501 257 0.026
biological adhesion GO:0022610 138 0.026
peptidyl threonine phosphorylation GO:0018107 2 0.026
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.026
rna interference GO:0016246 27 0.025
apoptotic process GO:0006915 159 0.025
salivary gland development GO:0007431 162 0.025
cellular response to unfolded protein GO:0034620 9 0.025
cellular catabolic process GO:0044248 372 0.025
negative regulation of transcription dna templated GO:0045892 237 0.025
regulation of dendrite morphogenesis GO:0048814 28 0.024
notch signaling pathway GO:0007219 120 0.024
ectodermal placode morphogenesis GO:0071697 4 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
intracellular protein transport GO:0006886 104 0.024
dendrite development GO:0016358 204 0.024
glycosyl compound metabolic process GO:1901657 127 0.024
localization of cell GO:0051674 257 0.024
camera type eye morphogenesis GO:0048593 2 0.024
imaginal disc derived wing hair organization GO:0035317 45 0.024
regulation of tube size open tracheal system GO:0035151 43 0.024
cell adhesion GO:0007155 136 0.023
cellular protein localization GO:0034613 160 0.023
single organismal cell cell adhesion GO:0016337 45 0.023
positive regulation of molecular function GO:0044093 136 0.023
positive regulation of catalytic activity GO:0043085 118 0.023
nuclear division GO:0000280 332 0.023
response to extracellular stimulus GO:0009991 116 0.022
cell division GO:0051301 248 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.022
negative regulation of biosynthetic process GO:0009890 277 0.022
eggshell formation GO:0030703 105 0.021
spermatid differentiation GO:0048515 114 0.021
adherens junction organization GO:0034332 27 0.021
microtubule organizing center organization GO:0031023 168 0.021
regulation of ras protein signal transduction GO:0046578 93 0.021
oocyte microtubule cytoskeleton organization GO:0016325 35 0.020
induction of programmed cell death by ecdysone GO:0035078 12 0.020
malpighian tubule development GO:0072002 64 0.020
regulation of actin polymerization or depolymerization GO:0008064 27 0.020
negative regulation of cell differentiation GO:0045596 143 0.020
negative regulation of developmental process GO:0051093 201 0.020
kidney development GO:0001822 3 0.020
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
establishment of protein localization GO:0045184 163 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
regulation of imaginal disc growth GO:0045570 26 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
negative regulation of developmental growth GO:0048640 64 0.019
protein dna complex assembly GO:0065004 63 0.019
r3 r4 cell fate commitment GO:0007464 10 0.019
wnt signaling pathway GO:0016055 98 0.019
negative regulation of cell development GO:0010721 62 0.019
peptidyl threonine modification GO:0018210 3 0.019
olfactory learning GO:0008355 56 0.019
regulation of cellular component size GO:0032535 98 0.018
positive regulation of organelle organization GO:0010638 65 0.018
muscle tissue development GO:0060537 30 0.018
centrosome organization GO:0051297 163 0.018
amine metabolic process GO:0009308 12 0.018
regulation of cell fate commitment GO:0010453 29 0.018
cellular response to peptide GO:1901653 28 0.018
gonad development GO:0008406 50 0.018
presynaptic membrane organization GO:0097090 4 0.018
regulation of chromosome organization GO:0033044 64 0.018
developmental growth GO:0048589 280 0.017
adult locomotory behavior GO:0008344 76 0.017
cell cycle phase transition GO:0044770 140 0.017
germ line stem cell maintenance GO:0030718 50 0.017
brain development GO:0007420 120 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
regulation of cell substrate adhesion GO:0010810 2 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
positive regulation of protein metabolic process GO:0051247 128 0.017
rna processing GO:0006396 147 0.017
action potential GO:0001508 13 0.017
regulation of system process GO:0044057 36 0.017
response to gravity GO:0009629 26 0.017
establishment of organelle localization GO:0051656 122 0.017
pigmentation GO:0043473 75 0.017
phosphatidic acid metabolic process GO:0046473 1 0.017
muscle system process GO:0003012 21 0.017
positive regulation of signaling GO:0023056 243 0.017
non sensory hair organization GO:0035316 47 0.016
regulation of cell adhesion GO:0030155 27 0.016
centrosome cycle GO:0007098 137 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
striated muscle cell differentiation GO:0051146 90 0.016
single organism biosynthetic process GO:0044711 206 0.016
cuticle pigmentation GO:0048067 22 0.016
negative regulation of wnt signaling pathway GO:0030178 28 0.016
regulation of catalytic activity GO:0050790 185 0.016
circulatory system development GO:0072359 82 0.016
regulation of embryonic development GO:0045995 68 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
neuron recognition GO:0008038 101 0.016
regulation of developmental growth GO:0048638 174 0.015
heterochromatin organization GO:0070828 25 0.015
adherens junction assembly GO:0034333 11 0.015
positive regulation of cell motility GO:2000147 3 0.015
histone modification GO:0016570 106 0.015
regulation of cellular localization GO:0060341 136 0.015
regulation of cuticle pigmentation GO:0048079 16 0.015
muscle organ development GO:0007517 127 0.015
antimicrobial humoral response GO:0019730 99 0.015
macromolecule catabolic process GO:0009057 161 0.015
spermatid development GO:0007286 98 0.015
nucleus localization GO:0051647 34 0.015
induction of programmed cell death GO:0012502 12 0.015
retina morphogenesis in camera type eye GO:0060042 2 0.015
molting cycle process GO:0022404 29 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
protein localization to organelle GO:0033365 82 0.015
organonitrogen compound metabolic process GO:1901564 318 0.015
epidermis development GO:0008544 65 0.015
multicellular organismal movement GO:0050879 3 0.015
cell cell junction organization GO:0045216 55 0.014
regulation of notch signaling pathway GO:0008593 100 0.014
intracellular signal transduction GO:0035556 300 0.014
regulation of rna splicing GO:0043484 69 0.014
regulation of nervous system development GO:0051960 248 0.014
cellular component disassembly GO:0022411 46 0.014
formation of anatomical boundary GO:0048859 37 0.014
circulatory system process GO:0003013 37 0.014
regulation of transferase activity GO:0051338 58 0.014
muscle cell development GO:0055001 50 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
regulation of epidermal cell differentiation GO:0045604 3 0.013
regulation of intracellular transport GO:0032386 64 0.013
cell motility GO:0048870 251 0.013
digestive tract morphogenesis GO:0048546 127 0.013
secretion GO:0046903 109 0.013
nuclear transport GO:0051169 72 0.013
regulation of dna templated transcription in response to stress GO:0043620 4 0.013
positive regulation of signal transduction GO:0009967 223 0.013
establishment of cell polarity GO:0030010 40 0.013
humoral immune response GO:0006959 117 0.013
extracellular matrix organization GO:0030198 32 0.013
single organism behavior GO:0044708 391 0.013
regulation of programmed cell death GO:0043067 152 0.013
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.013
golgi organization GO:0007030 66 0.013
basement membrane organization GO:0071711 10 0.013
mitotic spindle organization GO:0007052 220 0.013
salivary gland morphogenesis GO:0007435 145 0.013
histone methylation GO:0016571 40 0.012
actin filament based process GO:0030029 220 0.012
negative regulation of imaginal disc growth GO:0045571 8 0.012
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.012
negative regulation of cell cycle GO:0045786 116 0.012
carbohydrate metabolic process GO:0005975 82 0.012
lamellipodium assembly GO:0030032 21 0.012
organelle fission GO:0048285 340 0.012
male meiosis GO:0007140 52 0.012
protein transport GO:0015031 155 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
negative regulation of epithelial cell proliferation GO:0050680 4 0.012
cell fate determination GO:0001709 91 0.012
anterior posterior pattern specification GO:0009952 136 0.012
modification dependent protein catabolic process GO:0019941 78 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
regulation of tube architecture open tracheal system GO:0035152 68 0.012
single organism nuclear import GO:1902593 51 0.012
histolysis GO:0007559 102 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
monocarboxylic acid transport GO:0015718 3 0.012
salivary gland histolysis GO:0035070 88 0.012
regulation of locomotion GO:0040012 42 0.012
cell type specific apoptotic process GO:0097285 38 0.012
endomembrane system organization GO:0010256 119 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
protein localization to nucleus GO:0034504 55 0.011
sensory perception of mechanical stimulus GO:0050954 72 0.011
organelle assembly GO:0070925 198 0.011
regulation of cell projection organization GO:0031344 92 0.011
synapse assembly GO:0007416 143 0.011
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.011
cellular macromolecule localization GO:0070727 220 0.011
regulation of cell junction assembly GO:1901888 2 0.011
reproductive behavior GO:0019098 122 0.011
positive regulation of cell adhesion GO:0045785 10 0.011
cuticle pattern formation GO:0035017 27 0.011
nucleoside catabolic process GO:0009164 112 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
actin filament based movement GO:0030048 26 0.011
larval somatic muscle development GO:0007526 19 0.011
cellular chemical homeostasis GO:0055082 40 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
regulation of cell matrix adhesion GO:0001952 1 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
regulation of actin cytoskeleton organization GO:0032956 42 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.010
multicellular organismal signaling GO:0035637 12 0.010
regulation of eye photoreceptor cell development GO:0042478 13 0.010
striated muscle cell development GO:0055002 50 0.010
regulation of tube diameter GO:0035296 14 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
autophagic vacuole fusion GO:0000046 15 0.010
positive regulation of cell communication GO:0010647 250 0.010
regulation of protein phosphorylation GO:0001932 64 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
filopodium assembly GO:0046847 33 0.010
spindle organization GO:0007051 253 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
regulation of cell death GO:0010941 173 0.010
negative regulation of neurogenesis GO:0050768 53 0.010
aromatic compound catabolic process GO:0019439 166 0.010
developmental induction GO:0031128 3 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010

CrebA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
auditory system disease DOID:2742 0 0.013
nonsyndromic deafness DOID:0050563 0 0.013
sensory system disease DOID:0050155 0 0.013
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013