Drosophila melanogaster

0 known processes

CG4538 (Dmel_CG4538)

CG4538 gene product from transcript CG4538-RA

(Aliases: Dmel\CG4538)

CG4538 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage development GO:0048736 401 0.152
response to organic substance GO:0010033 284 0.149
lateral inhibition GO:0046331 206 0.118
imaginal disc derived wing morphogenesis GO:0007476 337 0.108
appendage morphogenesis GO:0035107 397 0.102
localization of cell GO:0051674 257 0.084
wing disc morphogenesis GO:0007472 344 0.076
cell cell signaling involved in cell fate commitment GO:0045168 210 0.065
positive regulation of response to stimulus GO:0048584 323 0.065
protein localization GO:0008104 284 0.064
imaginal disc derived appendage development GO:0048737 399 0.063
positive regulation of cell communication GO:0010647 250 0.061
spermatid differentiation GO:0048515 114 0.061
positive regulation of signal transduction GO:0009967 223 0.061
positive regulation of signaling GO:0023056 243 0.059
post embryonic appendage morphogenesis GO:0035120 385 0.057
enzyme linked receptor protein signaling pathway GO:0007167 179 0.054
regulation of intracellular signal transduction GO:1902531 236 0.054
regulation of cell cycle GO:0051726 291 0.054
imaginal disc derived appendage morphogenesis GO:0035114 395 0.054
protein modification process GO:0036211 438 0.052
protein modification by small protein conjugation or removal GO:0070647 106 0.051
carboxylic acid metabolic process GO:0019752 92 0.046
negative regulation of cellular metabolic process GO:0031324 382 0.045
small molecule metabolic process GO:0044281 305 0.043
epithelial cell migration GO:0010631 148 0.042
growth GO:0040007 359 0.040
regulation of cellular catabolic process GO:0031329 157 0.040
intracellular signal transduction GO:0035556 300 0.040
death GO:0016265 284 0.039
regulation of notch signaling pathway GO:0008593 100 0.039
modification dependent macromolecule catabolic process GO:0043632 79 0.038
cellular protein modification process GO:0006464 438 0.038
organonitrogen compound metabolic process GO:1901564 318 0.038
catabolic process GO:0009056 409 0.038
male gamete generation GO:0048232 201 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.037
oxoacid metabolic process GO:0043436 103 0.036
regulation of growth GO:0040008 233 0.035
mitotic spindle organization GO:0007052 220 0.035
spermatogenesis GO:0007283 200 0.035
cell motility GO:0048870 251 0.035
vesicle mediated transport GO:0016192 381 0.034
endocytosis GO:0006897 310 0.034
cellular macromolecule localization GO:0070727 220 0.034
cellular response to chemical stimulus GO:0070887 199 0.033
digestive tract morphogenesis GO:0048546 127 0.033
regulation of response to stress GO:0080134 200 0.032
regulation of cell cycle process GO:0010564 181 0.032
negative regulation of cell communication GO:0010648 223 0.032
regulation of mapk cascade GO:0043408 92 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.032
regulation of catabolic process GO:0009894 170 0.032
organic acid metabolic process GO:0006082 103 0.031
phosphorylation GO:0016310 294 0.031
regulation of mitotic cell cycle GO:0007346 190 0.031
cell proliferation GO:0008283 299 0.030
macromolecule catabolic process GO:0009057 161 0.030
ubiquitin dependent protein catabolic process GO:0006511 78 0.030
spermatid development GO:0007286 98 0.029
cellular macromolecule catabolic process GO:0044265 136 0.029
epithelium migration GO:0090132 148 0.029
proteasomal protein catabolic process GO:0010498 59 0.029
negative regulation of gene expression GO:0010629 387 0.029
mapk cascade GO:0000165 107 0.028
tissue migration GO:0090130 155 0.028
negative regulation of mitotic cell cycle GO:0045930 109 0.028
cellular response to organic substance GO:0071310 132 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
response to abiotic stimulus GO:0009628 341 0.028
regulation of protein metabolic process GO:0051246 256 0.028
modification dependent protein catabolic process GO:0019941 78 0.028
cell migration GO:0016477 238 0.028
autophagy GO:0006914 108 0.027
regulation of cellular component biogenesis GO:0044087 201 0.027
cellular protein localization GO:0034613 160 0.027
nucleoside phosphate metabolic process GO:0006753 162 0.027
organophosphate metabolic process GO:0019637 195 0.027
cell maturation GO:0048469 144 0.027
response to endogenous stimulus GO:0009719 119 0.026
chromatin organization GO:0006325 207 0.026
cellular catabolic process GO:0044248 372 0.026
phagocytosis GO:0006909 215 0.026
protein modification by small protein removal GO:0070646 28 0.025
chromosome organization GO:0051276 360 0.025
tissue death GO:0016271 102 0.025
ion transmembrane transport GO:0034220 122 0.025
protein transport GO:0015031 155 0.025
negative regulation of cell cycle phase transition GO:1901988 103 0.025
epithelial cell differentiation GO:0030855 322 0.025
protein ubiquitination GO:0016567 70 0.024
digestive system development GO:0055123 149 0.024
nucleobase containing small molecule metabolic process GO:0055086 174 0.024
lipid metabolic process GO:0006629 121 0.024
notch signaling pathway GO:0007219 120 0.024
cellular protein catabolic process GO:0044257 83 0.023
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.023
response to radiation GO:0009314 155 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
negative regulation of signal transduction GO:0009968 206 0.023
organic substance catabolic process GO:1901575 308 0.023
intracellular transport GO:0046907 228 0.022
immune response regulating signaling pathway GO:0002764 2 0.022
posttranscriptional regulation of gene expression GO:0010608 145 0.022
nuclear division GO:0000280 332 0.022
single organism intracellular transport GO:1902582 207 0.022
programmed cell death GO:0012501 257 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
glycosyl compound metabolic process GO:1901657 127 0.022
purine nucleoside metabolic process GO:0042278 127 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
single organism biosynthetic process GO:0044711 206 0.022
negative regulation of immune system process GO:0002683 50 0.021
single organism behavior GO:0044708 391 0.021
cation transport GO:0006812 110 0.021
homeostatic process GO:0042592 199 0.021
cellular response to dna damage stimulus GO:0006974 223 0.021
transmembrane transport GO:0055085 139 0.021
establishment of localization in cell GO:0051649 402 0.021
eye development GO:0001654 323 0.020
regulation of cell cycle phase transition GO:1901987 130 0.020
response to oxygen containing compound GO:1901700 200 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.020
epithelial cell development GO:0002064 274 0.020
nucleoside metabolic process GO:0009116 127 0.020
cell cycle phase transition GO:0044770 140 0.020
developmental programmed cell death GO:0010623 138 0.020
wnt signaling pathway GO:0016055 98 0.020
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
organonitrogen compound biosynthetic process GO:1901566 117 0.020
establishment of protein localization GO:0045184 163 0.020
signal transduction by phosphorylation GO:0023014 107 0.019
gland morphogenesis GO:0022612 145 0.019
forebrain development GO:0030900 2 0.019
positive regulation of developmental process GO:0051094 143 0.019
cellular response to abiotic stimulus GO:0071214 58 0.019
sperm individualization GO:0007291 48 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
histolysis GO:0007559 102 0.019
tube development GO:0035295 244 0.019
chaeta development GO:0022416 97 0.019
exocrine system development GO:0035272 162 0.019
positive regulation of intracellular signal transduction GO:1902533 116 0.019
oligosaccharide transport GO:0015772 2 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
long chain fatty acid metabolic process GO:0001676 3 0.018
pyridine containing compound metabolic process GO:0072524 3 0.018
positive regulation of gene expression GO:0010628 290 0.018
protein catabolic process GO:0030163 101 0.018
regulation of organelle organization GO:0033043 196 0.018
detection of external stimulus GO:0009581 66 0.018
defense response GO:0006952 300 0.018
organelle localization GO:0051640 148 0.018
negative regulation of cell cycle process GO:0010948 109 0.018
regulation of immune system process GO:0002682 176 0.018
regulation of programmed cell death GO:0043067 152 0.018
developmental growth GO:0048589 280 0.018
tube morphogenesis GO:0035239 191 0.018
positive regulation of phosphate metabolic process GO:0045937 139 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
membrane organization GO:0061024 112 0.018
response to other organism GO:0051707 293 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
limb development GO:0060173 1 0.017
cell death GO:0008219 279 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.017
nicotinamide nucleotide metabolic process GO:0046496 2 0.017
oxidoreduction coenzyme metabolic process GO:0006733 2 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
ribonucleotide metabolic process GO:0009259 145 0.017
secretion GO:0046903 109 0.017
mesenchymal cell differentiation GO:0048762 1 0.017
ameboidal type cell migration GO:0001667 151 0.017
response to hexose GO:0009746 3 0.017
regulation of localization GO:0032879 275 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
nucleotide metabolic process GO:0009117 161 0.017
axon development GO:0061564 297 0.017
regulation of anatomical structure size GO:0090066 163 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
salivary gland histolysis GO:0035070 88 0.016
camera type eye development GO:0043010 4 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
mitotic cell cycle phase transition GO:0044772 138 0.016
organic substance transport GO:0071702 257 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
ion transport GO:0006811 145 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.016
response to endoplasmic reticulum stress GO:0034976 28 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
cellular response to endogenous stimulus GO:0071495 80 0.016
regulation of catalytic activity GO:0050790 185 0.016
response to lipopolysaccharide GO:0032496 4 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
immune response activating signal transduction GO:0002757 2 0.016
negative regulation of signaling GO:0023057 219 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
neurological system process GO:0050877 358 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
negative regulation of gene expression epigenetic GO:0045814 77 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
cellular response to growth factor stimulus GO:0071363 30 0.015
regulation of apoptotic process GO:0042981 130 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
salivary gland development GO:0007431 162 0.015
cell cell junction organization GO:0045216 55 0.015
response to external biotic stimulus GO:0043207 293 0.015
imaginal disc derived leg morphogenesis GO:0007480 80 0.015
single organism catabolic process GO:0044712 228 0.015
detection of visible light GO:0009584 38 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
compound eye development GO:0048749 307 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
cell division GO:0051301 248 0.015
regulation of cellular response to stress GO:0080135 89 0.015
mitotic nuclear division GO:0007067 213 0.015
segmentation GO:0035282 207 0.014
regionalization GO:0003002 416 0.014
cellular amine metabolic process GO:0044106 12 0.014
apoptotic process GO:0006915 159 0.014
cellular response to radiation GO:0071478 52 0.014
organelle fission GO:0048285 340 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
negative regulation of cell cycle GO:0045786 116 0.014
gastrulation involving germ band extension GO:0010004 36 0.014
amine metabolic process GO:0009308 12 0.014
cytoplasmic transport GO:0016482 130 0.014
purine containing compound metabolic process GO:0072521 155 0.014
secretion by cell GO:0032940 101 0.014
tricarboxylic acid metabolic process GO:0072350 1 0.014
single organism membrane organization GO:0044802 93 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
spindle organization GO:0007051 253 0.014
regulation of wnt signaling pathway GO:0030111 68 0.014
regulation of transport GO:0051049 181 0.014
taxis GO:0042330 304 0.014
phototransduction GO:0007602 52 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
establishment of epithelial cell polarity GO:0090162 13 0.014
endosomal transport GO:0016197 44 0.014
response to nitrogen compound GO:1901698 90 0.014
actin cytoskeleton organization GO:0030036 206 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
proteolysis GO:0006508 192 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
cell growth GO:0016049 108 0.013
regulation of defense response GO:0031347 102 0.013
telencephalon development GO:0021537 2 0.013
pyridine nucleotide metabolic process GO:0019362 2 0.013
autophagic cell death GO:0048102 83 0.013
response to biotic stimulus GO:0009607 294 0.013
actin filament organization GO:0007015 126 0.013
connective tissue development GO:0061448 3 0.013
defense response to other organism GO:0098542 225 0.013
defense response to bacterium GO:0042742 178 0.013
chromatin silencing GO:0006342 76 0.013
macromolecular complex assembly GO:0065003 256 0.013
regulation of hydrolase activity GO:0051336 97 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
protein complex assembly GO:0006461 200 0.013
developmental maturation GO:0021700 172 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
aromatic compound catabolic process GO:0019439 166 0.013
regulation of cellular response to growth factor stimulus GO:0090287 13 0.013
response to growth factor GO:0070848 31 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
regulation of phosphorylation GO:0042325 147 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
protein acylation GO:0043543 42 0.012
regulation of gtpase activity GO:0043087 44 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
body morphogenesis GO:0010171 2 0.012
salivary gland morphogenesis GO:0007435 145 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
triglyceride biosynthetic process GO:0019432 2 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
detection of stimulus GO:0051606 156 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
ovarian follicle cell development GO:0030707 248 0.012
anterior posterior pattern specification GO:0009952 136 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
cellular lipid metabolic process GO:0044255 83 0.012
actin filament based process GO:0030029 220 0.012
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
negative regulation of cell death GO:0060548 81 0.012
positive regulation of organelle organization GO:0010638 65 0.012
dephosphorylation GO:0016311 51 0.012
embryonic morphogenesis GO:0048598 206 0.012
positive regulation of cell motility GO:2000147 3 0.012
response to organic cyclic compound GO:0014070 89 0.012
regulation of response to external stimulus GO:0032101 115 0.012
single organism cellular localization GO:1902580 180 0.012
synapse assembly GO:0007416 143 0.012
rubidium ion transport GO:0035826 1 0.012
stress activated mapk cascade GO:0051403 52 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
regulation of immune response GO:0050776 118 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
gland development GO:0048732 191 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
regulation of synapse assembly GO:0051963 94 0.011
regulation of cellular component size GO:0032535 98 0.011
cellularization GO:0007349 90 0.011
regulation of heart morphogenesis GO:2000826 3 0.011
regulation of immune effector process GO:0002697 52 0.011
cellular response to extracellular stimulus GO:0031668 64 0.011
mesenchymal cell development GO:0014031 1 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
citrate metabolic process GO:0006101 0 0.011
regulation of protein modification process GO:0031399 112 0.011
dna metabolic process GO:0006259 227 0.011
regulation of gene silencing GO:0060968 63 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
protein localization to organelle GO:0033365 82 0.011
asymmetric cell division GO:0008356 37 0.011
neutral lipid biosynthetic process GO:0046460 2 0.011
retina development in camera type eye GO:0060041 4 0.011
regulation of cell division GO:0051302 72 0.011
multi multicellular organism process GO:0044706 123 0.011
regulation of developmental growth GO:0048638 174 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.011
digestive tract development GO:0048565 149 0.011
rrna processing GO:0006364 3 0.011
regulation of proteolysis GO:0030162 87 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
regulation of cell differentiation GO:0045595 302 0.011
positive regulation of cell migration GO:0030335 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
acylglycerol biosynthetic process GO:0046463 2 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.010
negative regulation of growth GO:0045926 84 0.010
cell cycle checkpoint GO:0000075 95 0.010
compound eye morphogenesis GO:0001745 249 0.010
nitrogen compound transport GO:0071705 85 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.010
jnk cascade GO:0007254 50 0.010
eye morphogenesis GO:0048592 260 0.010
stem cell differentiation GO:0048863 117 0.010
regulation of response to biotic stimulus GO:0002831 63 0.010
regulation of cellular protein catabolic process GO:1903362 44 0.010
protein k48 linked ubiquitination GO:0070936 3 0.010
establishment of protein localization to organelle GO:0072594 62 0.010
response to wounding GO:0009611 94 0.010
purine nucleoside monophosphate metabolic process GO:0009126 50 0.010
negative regulation of developmental process GO:0051093 201 0.010
regulation of molecular function GO:0065009 217 0.010
ribonucleoside monophosphate metabolic process GO:0009161 51 0.010
leg disc morphogenesis GO:0007478 80 0.010
response to alcohol GO:0097305 95 0.010
stress activated protein kinase signaling cascade GO:0031098 55 0.010

CG4538 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.026
inherited metabolic disorder DOID:655 0 0.023
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
organ system cancer DOID:0050686 0 0.010