Drosophila melanogaster

18 known processes

IM23 (Dmel_CG15066)

Immune induced molecule 23

(Aliases: DIM-23,BcDNA:RH67033,DIM 23,Dmel\CG15066,CG15066)

IM23 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to fungus GO:0009620 50 0.648
defense response GO:0006952 300 0.463
defense response to other organism GO:0098542 225 0.344
activation of innate immune response GO:0002218 4 0.263
regulation of histone h3 k9 methylation GO:0051570 3 0.224
humoral immune response GO:0006959 117 0.201
regulation of immune response GO:0050776 118 0.133
defense response to fungus GO:0050832 48 0.131
response to bacterium GO:0009617 198 0.129
defense response to gram positive bacterium GO:0050830 41 0.126
innate immune response activating signal transduction GO:0002758 2 0.123
regulation of defense response GO:0031347 102 0.102
chromosome organization GO:0051276 360 0.099
pattern recognition receptor signaling pathway GO:0002221 2 0.095
negative regulation of gene expression GO:0010629 387 0.093
chromatin organization GO:0006325 207 0.089
response to external biotic stimulus GO:0043207 293 0.089
positive regulation of defense response GO:0031349 59 0.087
protein modification process GO:0036211 438 0.086
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.084
negative regulation of cellular biosynthetic process GO:0031327 277 0.084
transcription from rna polymerase ii promoter GO:0006366 368 0.080
spermatogenesis GO:0007283 200 0.079
negative regulation of nucleic acid templated transcription GO:1903507 240 0.078
chromatin modification GO:0016568 147 0.078
negative regulation of rna biosynthetic process GO:1902679 240 0.073
response to other organism GO:0051707 293 0.071
antibacterial humoral response GO:0019731 44 0.071
regulation of growth GO:0040008 233 0.068
carbohydrate derivative metabolic process GO:1901135 217 0.067
histone modification GO:0016570 106 0.067
imaginal disc derived wing morphogenesis GO:0007476 337 0.064
defense response to bacterium GO:0042742 178 0.062
innate immune response GO:0045087 144 0.061
posttranscriptional regulation of gene expression GO:0010608 145 0.060
regulation of protein metabolic process GO:0051246 256 0.060
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.060
muscle organ development GO:0007517 127 0.059
organonitrogen compound metabolic process GO:1901564 318 0.058
regulation of organelle organization GO:0033043 196 0.056
positive regulation of response to stimulus GO:0048584 323 0.056
covalent chromatin modification GO:0016569 106 0.055
appendage morphogenesis GO:0035107 397 0.055
negative regulation of biosynthetic process GO:0009890 277 0.053
protein localization GO:0008104 284 0.052
negative regulation of cellular metabolic process GO:0031324 382 0.052
cell growth GO:0016049 108 0.052
immune response GO:0006955 246 0.051
wing disc morphogenesis GO:0007472 344 0.049
protein localization to chromatin GO:0071168 3 0.049
male gamete generation GO:0048232 201 0.047
cellular macromolecule localization GO:0070727 220 0.047
response to organic substance GO:0010033 284 0.046
regulation of innate immune response GO:0045088 71 0.046
imaginal disc derived appendage development GO:0048737 399 0.046
cellular protein modification process GO:0006464 438 0.045
cellular protein localization GO:0034613 160 0.044
positive regulation of macromolecule metabolic process GO:0010604 405 0.043
positive regulation of growth GO:0045927 75 0.043
regulation of chromosome organization GO:0033044 64 0.042
positive regulation of cellular protein metabolic process GO:0032270 118 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.041
growth GO:0040007 359 0.040
organic substance catabolic process GO:1901575 308 0.039
appendage development GO:0048736 401 0.039
peptidoglycan metabolic process GO:0000270 3 0.036
immune response regulating signaling pathway GO:0002764 2 0.035
catabolic process GO:0009056 409 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.035
post embryonic appendage morphogenesis GO:0035120 385 0.034
organelle fission GO:0048285 340 0.034
ovarian follicle cell development GO:0030707 248 0.034
phosphorylation GO:0016310 294 0.034
regulation of cellular protein metabolic process GO:0032268 243 0.033
histone lysine methylation GO:0034968 32 0.033
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
protein alkylation GO:0008213 43 0.032
histone methylation GO:0016571 40 0.032
taxis GO:0042330 304 0.032
regulation of chromatin modification GO:1903308 28 0.031
positive regulation of cellular component organization GO:0051130 156 0.030
small molecule metabolic process GO:0044281 305 0.030
amine metabolic process GO:0009308 12 0.030
antifungal humoral response GO:0019732 12 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.030
negative regulation of rna metabolic process GO:0051253 251 0.028
regulation of chromatin organization GO:1902275 32 0.028
cellular amine metabolic process GO:0044106 12 0.028
epithelium migration GO:0090132 148 0.028
nuclear division GO:0000280 332 0.028
regulation of response to stress GO:0080134 200 0.027
regionalization GO:0003002 416 0.027
muscle structure development GO:0061061 224 0.027
positive regulation of protein metabolic process GO:0051247 128 0.026
negative regulation of transcription dna templated GO:0045892 237 0.026
body morphogenesis GO:0010171 2 0.026
regulation of immune system process GO:0002682 176 0.026
response to abiotic stimulus GO:0009628 341 0.026
neuron projection guidance GO:0097485 241 0.026
positive regulation of organelle organization GO:0010638 65 0.026
regulation of histone modification GO:0031056 20 0.025
macromolecule catabolic process GO:0009057 161 0.025
establishment of protein localization GO:0045184 163 0.025
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.025
cellular catabolic process GO:0044248 372 0.025
response to organophosphorus GO:0046683 2 0.025
detection of chemical stimulus GO:0009593 93 0.025
positive regulation of signaling GO:0023056 243 0.025
epithelial cell development GO:0002064 274 0.025
synaptic transmission GO:0007268 288 0.024
intracellular signal transduction GO:0035556 300 0.024
macromolecule methylation GO:0043414 45 0.024
positive regulation of signal transduction GO:0009967 223 0.024
chemotaxis GO:0006935 249 0.024
ethanolamine containing compound metabolic process GO:0042439 4 0.023
response to biotic stimulus GO:0009607 294 0.023
regulation of multicellular organismal development GO:2000026 414 0.023
columnar cuboidal epithelial cell development GO:0002066 249 0.023
establishment of protein localization to organelle GO:0072594 62 0.023
cell motility GO:0048870 251 0.023
epithelial cell differentiation GO:0030855 322 0.023
neurotransmitter metabolic process GO:0042133 2 0.022
localization of cell GO:0051674 257 0.022
immune response activating signal transduction GO:0002757 2 0.022
forebrain development GO:0030900 2 0.022
positive regulation of cell communication GO:0010647 250 0.022
death GO:0016265 284 0.021
phagocytosis GO:0006909 215 0.021
regulation of anatomical structure size GO:0090066 163 0.021
female meiotic division GO:0007143 70 0.021
response to lipopolysaccharide GO:0032496 4 0.021
single organism behavior GO:0044708 391 0.020
positive regulation of histone h3 k9 methylation GO:0051574 3 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
acetylcholine metabolic process GO:0008291 2 0.020
single organism catabolic process GO:0044712 228 0.020
oxoacid metabolic process GO:0043436 103 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
endocytosis GO:0006897 310 0.020
organic acid metabolic process GO:0006082 103 0.020
developmental growth GO:0048589 280 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
choline metabolic process GO:0019695 1 0.019
regulation of cell cycle GO:0051726 291 0.019
establishment of blood nerve barrier GO:0008065 2 0.019
immune system process GO:0002376 347 0.019
homeostatic process GO:0042592 199 0.019
chromosome segregation GO:0007059 157 0.019
meiotic cell cycle process GO:1903046 132 0.019
steroid catabolic process GO:0006706 1 0.019
ameboidal type cell migration GO:0001667 151 0.019
cell migration GO:0016477 238 0.019
axon guidance GO:0007411 233 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.018
xenobiotic catabolic process GO:0042178 1 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
programmed cell death GO:0012501 257 0.018
cell cell junction assembly GO:0007043 38 0.018
respiratory system development GO:0060541 213 0.018
defense response to gram negative bacterium GO:0050829 94 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
secondary metabolite catabolic process GO:0090487 1 0.018
camera type eye development GO:0043010 4 0.018
intracellular transport GO:0046907 228 0.017
regulation of defense response to bacterium GO:1900424 30 0.017
positive regulation of gene expression GO:0010628 290 0.017
open tracheal system development GO:0007424 204 0.017
negative regulation of cell communication GO:0010648 223 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
mitotic nuclear division GO:0007067 213 0.017
cellular ketone metabolic process GO:0042180 24 0.017
compound eye development GO:0048749 307 0.017
vesicle mediated transport GO:0016192 381 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.017
neurological system process GO:0050877 358 0.017
negative regulation of developmental process GO:0051093 201 0.017
connective tissue development GO:0061448 3 0.017
positive regulation of cell motility GO:2000147 3 0.017
axon development GO:0061564 297 0.016
regulation of cell differentiation GO:0045595 302 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
axonogenesis GO:0007409 290 0.016
acetylcholine catabolic process GO:0006581 1 0.016
estrogen metabolic process GO:0008210 1 0.016
establishment of localization in cell GO:0051649 402 0.015
positive regulation of cell migration GO:0030335 2 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
response to radiation GO:0009314 155 0.015
protein phosphorylation GO:0006468 169 0.015
negative regulation of signal transduction GO:0009968 206 0.015
multi organism behavior GO:0051705 175 0.015
segmentation GO:0035282 207 0.015
regulation of cell development GO:0060284 215 0.015
cell division GO:0051301 248 0.015
aminoglycan metabolic process GO:0006022 18 0.015
amine catabolic process GO:0009310 1 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
ion transport GO:0006811 145 0.015
response to oxygen containing compound GO:1901700 200 0.015
cell recognition GO:0008037 102 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
regulation of catalytic activity GO:0050790 185 0.014
positive regulation of innate immune response GO:0045089 38 0.014
spindle organization GO:0007051 253 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
regulation of nervous system development GO:0051960 248 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
regulation of catabolic process GO:0009894 170 0.014
regulation of molecular function GO:0065009 217 0.014
telencephalon development GO:0021537 2 0.014
response to glucose GO:0009749 2 0.014
single organism intracellular transport GO:1902582 207 0.014
cell junction organization GO:0034330 57 0.014
sensory perception of chemical stimulus GO:0007606 116 0.014
cell death GO:0008219 279 0.014
cell proliferation GO:0008283 299 0.014
response to monosaccharide GO:0034284 4 0.014
regulation of protein modification process GO:0031399 112 0.014
cell cell junction organization GO:0045216 55 0.014
negative regulation of signaling GO:0023057 219 0.014
limb development GO:0060173 1 0.014
cell cycle phase transition GO:0044770 140 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
acetate ester metabolic process GO:1900619 2 0.013
proteolysis GO:0006508 192 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
regulation of cell cycle process GO:0010564 181 0.013
neuron recognition GO:0008038 101 0.013
eye development GO:0001654 323 0.013
response to hexose GO:0009746 3 0.013
regulation of apoptotic process GO:0042981 130 0.013
protein methylation GO:0006479 43 0.013
anatomical structure homeostasis GO:0060249 97 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
epidermis development GO:0008544 65 0.013
cell adhesion GO:0007155 136 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
male mating behavior GO:0060179 70 0.013
neutral lipid biosynthetic process GO:0046460 2 0.013
meiotic chromosome segregation GO:0045132 59 0.013
benzene containing compound metabolic process GO:0042537 3 0.013
maintenance of location GO:0051235 73 0.013
developmental maturation GO:0021700 172 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
methylation GO:0032259 47 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
regulation of programmed cell death GO:0043067 152 0.013
ras protein signal transduction GO:0007265 88 0.013
hindbrain development GO:0030902 2 0.013
biological adhesion GO:0022610 138 0.013
response to light stimulus GO:0009416 124 0.013
chemosensory behavior GO:0007635 106 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
spermatid differentiation GO:0048515 114 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.012
organic substance transport GO:0071702 257 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
cellular response to ethanol GO:0071361 4 0.012
choline catabolic process GO:0042426 1 0.012
meiotic nuclear division GO:0007126 151 0.012
lipid localization GO:0010876 54 0.012
positive regulation of developmental process GO:0051094 143 0.012
vitamin metabolic process GO:0006766 2 0.012
locomotory behavior GO:0007626 176 0.012
epithelial cell migration GO:0010631 148 0.012
regulation of cell death GO:0010941 173 0.012
camera type eye morphogenesis GO:0048593 2 0.012
epidermal cell differentiation GO:0009913 51 0.012
cation transport GO:0006812 110 0.012
macromolecular complex assembly GO:0065003 256 0.012
single organism biosynthetic process GO:0044711 206 0.012
aromatic compound catabolic process GO:0019439 166 0.012
gland development GO:0048732 191 0.012
reproductive behavior GO:0019098 122 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
positive regulation of molecular function GO:0044093 136 0.012
antimicrobial humoral response GO:0019730 99 0.012
regulation of developmental growth GO:0048638 174 0.012
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
axis specification GO:0009798 167 0.012
mitotic spindle organization GO:0007052 220 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
neurotransmitter catabolic process GO:0042135 1 0.012
polyol biosynthetic process GO:0046173 3 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
chaeta development GO:0022416 97 0.012
meiotic cell cycle GO:0051321 171 0.012
regulation of epithelial cell proliferation GO:0050678 4 0.012
regulation of localization GO:0032879 275 0.012
positive regulation of immune system process GO:0002684 68 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
kidney development GO:0001822 3 0.011
organelle assembly GO:0070925 198 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
actin filament based process GO:0030029 220 0.011
female meiosis chromosome segregation GO:0016321 33 0.011
imaginal disc derived wing hair organization GO:0035317 45 0.011
cholesterol homeostasis GO:0042632 3 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
endomembrane system organization GO:0010256 119 0.011
dorsal ventral axis specification GO:0009950 66 0.011
septate junction assembly GO:0019991 26 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
protein localization to organelle GO:0033365 82 0.011
apoptotic process GO:0006915 159 0.011
positive regulation of protein modification process GO:0031401 58 0.011
mating GO:0007618 120 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
actin cytoskeleton organization GO:0030036 206 0.011
peripheral nervous system development GO:0007422 52 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
medium chain fatty acid metabolic process GO:0051791 1 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
metal ion transport GO:0030001 74 0.011
purine containing compound metabolic process GO:0072521 155 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
melanization defense response GO:0035006 45 0.011
protein heterooligomerization GO:0051291 4 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
detection of external biotic stimulus GO:0098581 2 0.011
mesenchymal cell development GO:0014031 1 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
positive regulation of immune response GO:0050778 63 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
cellular biogenic amine catabolic process GO:0042402 1 0.011
sensory perception of smell GO:0007608 80 0.010
cell cycle checkpoint GO:0000075 95 0.010
gland morphogenesis GO:0022612 145 0.010
dna metabolic process GO:0006259 227 0.010
regulation of synapse structure and activity GO:0050803 128 0.010
mesenchymal cell differentiation GO:0048762 1 0.010
heterocycle catabolic process GO:0046700 166 0.010
eye morphogenesis GO:0048592 260 0.010
synaptic target recognition GO:0008039 45 0.010
cellular response to organic substance GO:0071310 132 0.010
gene silencing GO:0016458 138 0.010
pheromone biosynthetic process GO:0042811 3 0.010
androgen metabolic process GO:0008209 1 0.010
organophosphate metabolic process GO:0019637 195 0.010
non sensory hair organization GO:0035316 47 0.010
nucleotide metabolic process GO:0009117 161 0.010
adult behavior GO:0030534 137 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
protein transport GO:0015031 155 0.010
regulation of lipid transport GO:0032368 3 0.010
retina development in camera type eye GO:0060041 4 0.010
regulation of cell growth GO:0001558 43 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
blastoderm segmentation GO:0007350 159 0.010
mating behavior GO:0007617 106 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
tissue migration GO:0090130 155 0.010
developmental programmed cell death GO:0010623 138 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
negative regulation of cell cycle GO:0045786 116 0.010
g protein coupled receptor signaling pathway GO:0007186 136 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.010
exocrine system development GO:0035272 162 0.010

IM23 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.041
disease of anatomical entity DOID:7 0 0.029
cardiovascular system disease DOID:1287 0 0.017
vascular disease DOID:178 0 0.016
inherited metabolic disorder DOID:655 0 0.014
nervous system disease DOID:863 0 0.014
acquired metabolic disease DOID:0060158 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
musculoskeletal system disease DOID:17 0 0.010