Drosophila melanogaster

76 known processes

tilB (Dmel_CG14620)

touch insensitive larva B

(Aliases: Dmel\CG14620,CG14620)

tilB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 38 0.999
axoneme assembly GO:0035082 18 0.989
cilium morphogenesis GO:0060271 39 0.983
cilium organization GO:0044782 41 0.976
sensory perception of mechanical stimulus GO:0050954 72 0.954
male courtship behavior GO:0008049 63 0.941
courtship behavior GO:0007619 68 0.904
neurological system process GO:0050877 358 0.863
mating behavior GO:0007617 106 0.851
multi organism behavior GO:0051705 175 0.851
sensory perception GO:0007600 196 0.849
sensory perception of sound GO:0007605 56 0.841
reproductive behavior GO:0019098 122 0.823
single organism behavior GO:0044708 391 0.817
microtubule bundle formation GO:0001578 27 0.807
locomotory behavior GO:0007626 176 0.744
cellular component assembly involved in morphogenesis GO:0010927 151 0.718
mating GO:0007618 120 0.713
intraciliary transport GO:0042073 8 0.520
cell projection assembly GO:0030031 94 0.507
multi multicellular organism process GO:0044706 123 0.496
multicellular organismal reproductive behavior GO:0033057 110 0.477
male courtship behavior veined wing extension GO:0048065 22 0.408
male gamete generation GO:0048232 201 0.390
organelle assembly GO:0070925 198 0.385
multi organism reproductive behavior GO:0044705 121 0.383
male mating behavior GO:0060179 70 0.381
microtubule based transport GO:0010970 42 0.381
locomotor rhythm GO:0045475 56 0.344
sperm axoneme assembly GO:0007288 13 0.330
response to mechanical stimulus GO:0009612 28 0.288
nonmotile primary cilium assembly GO:0035058 8 0.243
male courtship behavior veined wing vibration GO:0016545 21 0.232
spermatid differentiation GO:0048515 114 0.219
positive regulation of signal transduction GO:0009967 223 0.210
male courtship behavior veined wing generated song production GO:0045433 20 0.196
positive regulation of response to stimulus GO:0048584 323 0.193
spermatogenesis GO:0007283 200 0.181
adult locomotory behavior GO:0008344 76 0.168
response to abiotic stimulus GO:0009628 341 0.168
circadian rhythm GO:0007623 105 0.159
regionalization GO:0003002 416 0.152
Zebrafish
spermatid development GO:0007286 98 0.142
cellular response to organic substance GO:0071310 132 0.141
response to auditory stimulus GO:0010996 5 0.131
adult behavior GO:0030534 137 0.129
auditory behavior GO:0031223 1 0.122
cellular response to chemical stimulus GO:0070887 199 0.119
response to organic substance GO:0010033 284 0.116
cellular response to acid chemical GO:0071229 8 0.113
response to oxygen containing compound GO:1901700 200 0.106
regulation of anatomical structure morphogenesis GO:0022603 242 0.102
positive regulation of signaling GO:0023056 243 0.100
circadian behavior GO:0048512 76 0.100
negative regulation of transcription dna templated GO:0045892 237 0.099
response to endogenous stimulus GO:0009719 119 0.097
eye development GO:0001654 323 0.091
rhythmic process GO:0048511 106 0.086
rhythmic behavior GO:0007622 76 0.085
antennal morphogenesis GO:0048800 14 0.085
cellular response to endogenous stimulus GO:0071495 80 0.083
kidney development GO:0001822 3 0.082
Zebrafish
protein maturation GO:0051604 71 0.078
eye morphogenesis GO:0048592 260 0.077
intracellular signal transduction GO:0035556 300 0.074
cognition GO:0050890 141 0.073
protein processing GO:0016485 68 0.068
startle response GO:0001964 16 0.068
response to acid chemical GO:0001101 25 0.066
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.066
mechanosensory behavior GO:0007638 12 0.066
regulation of localization GO:0032879 275 0.064
cellular response to organonitrogen compound GO:0071417 36 0.063
sensory organ morphogenesis GO:0090596 260 0.061
appendage development GO:0048736 401 0.060
actin filament based movement GO:0030048 26 0.059
positive regulation of intracellular signal transduction GO:1902533 116 0.056
dendrite development GO:0016358 204 0.054
apical constriction GO:0003383 18 0.053
localization of cell GO:0051674 257 0.053
dorsal ventral pattern formation GO:0009953 133 0.053
Zebrafish
appendage morphogenesis GO:0035107 397 0.051
regulation of transport GO:0051049 181 0.050
negative regulation of signaling GO:0023057 219 0.050
organonitrogen compound metabolic process GO:1901564 318 0.049
response to organonitrogen compound GO:0010243 75 0.047
sensory perception of touch GO:0050975 11 0.046
compound eye development GO:0048749 307 0.045
response to radiation GO:0009314 155 0.044
segmentation GO:0035282 207 0.043
forebrain development GO:0030900 2 0.043
cellular response to oxygen containing compound GO:1901701 79 0.042
endocytosis GO:0006897 310 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.042
negative regulation of signal transduction GO:0009968 206 0.040
embryonic morphogenesis GO:0048598 206 0.040
Zebrafish
negative regulation of gene expression GO:0010629 387 0.039
synaptic transmission GO:0007268 288 0.039
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.039
smoothened signaling pathway GO:0007224 49 0.038
dendrite morphogenesis GO:0048813 199 0.037
negative regulation of cell communication GO:0010648 223 0.037
spermatid nucleus elongation GO:0007290 4 0.037
homeostatic process GO:0042592 199 0.036
intraspecies interaction between organisms GO:0051703 4 0.036
regulation of cell differentiation GO:0045595 302 0.036
enzyme linked receptor protein signaling pathway GO:0007167 179 0.036
establishment of localization in cell GO:0051649 402 0.035
regulation of intracellular signal transduction GO:1902531 236 0.035
limb morphogenesis GO:0035108 1 0.034
intracellular transport GO:0046907 228 0.034
epithelial cell development GO:0002064 274 0.034
phagocytosis GO:0006909 215 0.034
detection of stimulus GO:0051606 156 0.034
ion transport GO:0006811 145 0.033
macromolecule catabolic process GO:0009057 161 0.033
epidermis development GO:0008544 65 0.033
negative regulation of rna biosynthetic process GO:1902679 240 0.033
sensory perception of salty taste GO:0050914 3 0.032
brain development GO:0007420 120 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.032
limb development GO:0060173 1 0.032
regulation of organ morphogenesis GO:2000027 78 0.032
organic substance catabolic process GO:1901575 308 0.031
chemotaxis GO:0006935 249 0.031
negative regulation of rna metabolic process GO:0051253 251 0.031
protein localization GO:0008104 284 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.030
negative regulation of nucleic acid templated transcription GO:1903507 240 0.030
flight behavior GO:0007629 26 0.030
peripheral nervous system development GO:0007422 52 0.030
nucleobase containing small molecule metabolic process GO:0055086 174 0.030
mitotic spindle organization GO:0007052 220 0.029
response to nutrient levels GO:0031667 114 0.029
cell motility GO:0048870 251 0.029
regulation of neurogenesis GO:0050767 158 0.028
negative regulation of biosynthetic process GO:0009890 277 0.028
transcription from rna polymerase ii promoter GO:0006366 368 0.028
signal transduction by phosphorylation GO:0023014 107 0.028
cellular catabolic process GO:0044248 372 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
actin mediated cell contraction GO:0070252 21 0.027
regulation of cell morphogenesis GO:0022604 163 0.027
epithelial cell differentiation GO:0030855 322 0.027
small molecule metabolic process GO:0044281 305 0.026
oxoacid metabolic process GO:0043436 103 0.026
growth GO:0040007 359 0.026
phosphorylation GO:0016310 294 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.026
peptide metabolic process GO:0006518 80 0.025
axon development GO:0061564 297 0.025
glycosyl compound metabolic process GO:1901657 127 0.025
learning or memory GO:0007611 141 0.025
behavioral response to pain GO:0048266 3 0.024
compound eye morphogenesis GO:0001745 249 0.024
eye antennal disc development GO:0035214 60 0.024
regulation of tor signaling GO:0032006 21 0.024
cellular response to nitrogen compound GO:1901699 51 0.024
entrainment of circadian clock GO:0009649 16 0.024
regulation of cell development GO:0060284 215 0.024
negative regulation of response to stimulus GO:0048585 258 0.023
spinal cord development GO:0021510 1 0.023
regulation of synaptic activity GO:0060025 9 0.023
cellular response to starvation GO:0009267 61 0.023
positive regulation of apoptotic signaling pathway GO:2001235 4 0.022
cellular macromolecule catabolic process GO:0044265 136 0.022
retina development in camera type eye GO:0060041 4 0.022
negative regulation of cellular biosynthetic process GO:0031327 277 0.022
renal system development GO:0072001 72 0.022
Zebrafish
cranial nerve development GO:0021545 1 0.022
catabolic process GO:0009056 409 0.022
response to nitrogen compound GO:1901698 90 0.022
regulation of protein metabolic process GO:0051246 256 0.022
single organism catabolic process GO:0044712 228 0.021
vesicle mediated transport GO:0016192 381 0.021
organic acid metabolic process GO:0006082 103 0.021
synapse assembly GO:0007416 143 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
cellular response to external stimulus GO:0071496 66 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
aggressive behavior GO:0002118 63 0.020
cellular homeostasis GO:0019725 80 0.020
response to organophosphorus GO:0046683 2 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
gland development GO:0048732 191 0.020
regulation of retinal cell programmed cell death GO:0046668 18 0.020
response to pain GO:0048265 3 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.019
axon guidance GO:0007411 233 0.019
compound eye photoreceptor development GO:0042051 78 0.019
regulation of intracellular transport GO:0032386 64 0.019
taxis GO:0042330 304 0.018
cell death GO:0008219 279 0.018
tissue morphogenesis GO:0048729 297 0.018
Zebrafish
regulation of cellular localization GO:0060341 136 0.018
regulation of programmed cell death GO:0043067 152 0.018
proteolysis GO:0006508 192 0.018
inorganic cation transmembrane transport GO:0098662 61 0.018
cellular amide metabolic process GO:0043603 80 0.018
cellularization GO:0007349 90 0.018
respiratory system development GO:0060541 213 0.018
organelle fission GO:0048285 340 0.017
regulation of cellular response to growth factor stimulus GO:0090287 13 0.017
cellular macromolecule localization GO:0070727 220 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
single organism intracellular transport GO:1902582 207 0.017
neuromuscular process GO:0050905 21 0.017
nucleotide metabolic process GO:0009117 161 0.017
metal ion homeostasis GO:0055065 44 0.017
ion transmembrane transport GO:0034220 122 0.017
microtubule based movement GO:0007018 51 0.016
Zebrafish
detection of stimulus involved in sensory perception GO:0050906 92 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
protein complex assembly GO:0006461 200 0.016
sperm individualization GO:0007291 48 0.016
autophagy GO:0006914 108 0.016
regulation of embryonic development GO:0045995 68 0.016
embryonic pattern specification GO:0009880 174 0.016
regulation of cell cycle GO:0051726 291 0.016
regulation of microtubule based process GO:0032886 49 0.016
eye antennal disc morphogenesis GO:0007455 34 0.016
wound healing spreading of epidermal cells GO:0035313 1 0.016
cellular response to nutrient levels GO:0031669 62 0.016
response to glucose GO:0009749 2 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
regulation of circadian rhythm GO:0042752 49 0.015
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.015
regulation of smoothened signaling pathway GO:0008589 28 0.015
non sensory hair organization GO:0035316 47 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
wing disc morphogenesis GO:0007472 344 0.015
molting cycle chitin based cuticle GO:0007591 56 0.015
cellular response to mechanical stimulus GO:0071260 2 0.015
programmed cell death GO:0012501 257 0.015
dna damage checkpoint GO:0000077 78 0.015
immune effector process GO:0002252 98 0.015
developmental maturation GO:0021700 172 0.015
blastoderm segmentation GO:0007350 159 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.015
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.014
monovalent inorganic cation transport GO:0015672 40 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
cytoskeleton dependent intracellular transport GO:0030705 44 0.014
ion homeostasis GO:0050801 55 0.014
camera type eye development GO:0043010 4 0.014
regulation of cell death GO:0010941 173 0.014
response to biotic stimulus GO:0009607 294 0.014
response to wounding GO:0009611 94 0.014
centriole replication GO:0007099 24 0.014
centriole assembly GO:0098534 24 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
regulation of response to external stimulus GO:0032101 115 0.013
energy derivation by oxidation of organic compounds GO:0015980 32 0.013
response to lipopolysaccharide GO:0032496 4 0.013
exocrine system development GO:0035272 162 0.013
central nervous system development GO:0007417 201 0.013
single organism biosynthetic process GO:0044711 206 0.013
spinal cord patterning GO:0021511 1 0.013
regulation of nervous system development GO:0051960 248 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
protein catabolic process GO:0030163 101 0.013
cell cycle checkpoint GO:0000075 95 0.013
protein modification process GO:0036211 438 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
actin filament organization GO:0007015 126 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.013
wing disc pattern formation GO:0035222 66 0.013
cation homeostasis GO:0055080 51 0.013
positive regulation of cell communication GO:0010647 250 0.013
death GO:0016265 284 0.013
specification of symmetry GO:0009799 13 0.012
Zebrafish
purine nucleotide metabolic process GO:0006163 146 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
cation transport GO:0006812 110 0.012
cellular protein modification process GO:0006464 438 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
lateral inhibition GO:0046331 206 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
cellular protein localization GO:0034613 160 0.012
nucleoside monophosphate metabolic process GO:0009123 52 0.012
actin filament based process GO:0030029 220 0.012
cellular chemical homeostasis GO:0055082 40 0.012
epithelial cell morphogenesis GO:0003382 25 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.012
compound eye retinal cell programmed cell death GO:0046667 23 0.012
learning GO:0007612 75 0.012
regulation of response to extracellular stimulus GO:0032104 18 0.012
drinking behavior GO:0042756 2 0.012
body morphogenesis GO:0010171 2 0.012
associative learning GO:0008306 65 0.012
atp metabolic process GO:0046034 49 0.012
organic substance transport GO:0071702 257 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
positive regulation of axonogenesis GO:0050772 2 0.012
cellular respiration GO:0045333 26 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
epiboly GO:0090504 2 0.011
regulation of growth GO:0040008 233 0.011
response to other organism GO:0051707 293 0.011
photoreceptor cell development GO:0042461 96 0.011
segment polarity determination GO:0007367 25 0.011
regulation of response to nutrient levels GO:0032107 18 0.011
membrane depolarization GO:0051899 4 0.011
developmental programmed cell death GO:0010623 138 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
oxidation reduction process GO:0055114 123 0.011
ribonucleoside monophosphate metabolic process GO:0009161 51 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
response to extracellular stimulus GO:0009991 116 0.011
regulation of response to stress GO:0080134 200 0.011
neurotransmitter metabolic process GO:0042133 2 0.011
imaginal disc derived wing hair organization GO:0035317 45 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
neural retina development GO:0003407 4 0.011
chaeta development GO:0022416 97 0.011
mapk cascade GO:0000165 107 0.011
response to external biotic stimulus GO:0043207 293 0.010
developmental growth GO:0048589 280 0.010
response to heat GO:0009408 63 0.010
l amino acid import GO:0043092 2 0.010
negative regulation of cell death GO:0060548 81 0.010
proteasomal protein catabolic process GO:0010498 59 0.010
regulation of catabolic process GO:0009894 170 0.010
eye photoreceptor cell development GO:0042462 81 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
cation transmembrane transport GO:0098655 88 0.010

tilB disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
respiratory system disease DOID:1579 0 0.195
lower respiratory tract disease DOID:0050161 0 0.195
bronchial disease DOID:1176 0 0.195
disease of anatomical entity DOID:7 0 0.195
nervous system disease DOID:863 0 0.054
renal tubular transport disease DOID:447 0 0.035
kidney disease DOID:557 0 0.035
urinary system disease DOID:18 0 0.035
bronchiectasis DOID:9563 0 0.024
sensory system disease DOID:0050155 0 0.021
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016
auditory system disease DOID:2742 0 0.013
liddle syndrome DOID:0050477 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
heart conduction disease DOID:10273 0 0.011
cardiovascular system disease DOID:1287 0 0.011
eye and adnexa disease DOID:1492 0 0.010