Drosophila melanogaster

96 known processes

Pdp1 (Dmel_CG17888)

PAR-domain protein 1

(Aliases: pdp1epsilon,Pdp1epsilon,pdp1,CG17888,pdp,PDP1,Dmel\CG17888,anon-WO0140519.206)

Pdp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
circadian behavior GO:0048512 76 0.866
circadian rhythm GO:0007623 105 0.725
rhythmic behavior GO:0007622 76 0.714
rhythmic process GO:0048511 106 0.658
purine containing compound biosynthetic process GO:0072522 30 0.391
locomotor rhythm GO:0045475 56 0.337
locomotory behavior GO:0007626 176 0.184
ribonucleotide biosynthetic process GO:0009260 28 0.166
mating behavior GO:0007617 106 0.148
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.144
neuropeptide signaling pathway GO:0007218 45 0.133
single organism behavior GO:0044708 391 0.130
multicellular organismal reproductive behavior GO:0033057 110 0.124
small molecule metabolic process GO:0044281 305 0.120
reproductive behavior GO:0019098 122 0.118
regulation of secretion by cell GO:1903530 39 0.117
organonitrogen compound metabolic process GO:1901564 318 0.109
negative regulation of signaling GO:0023057 219 0.105
purine ribonucleotide biosynthetic process GO:0009152 28 0.104
nucleoside phosphate biosynthetic process GO:1901293 34 0.102
regulation of camp biosynthetic process GO:0030817 12 0.100
cardiovascular system development GO:0072358 82 0.095
ribose phosphate biosynthetic process GO:0046390 28 0.095
positive regulation of cellular biosynthetic process GO:0031328 316 0.091
response to insulin GO:0032868 29 0.088
nucleotide biosynthetic process GO:0009165 34 0.083
ion transport GO:0006811 145 0.083
mating GO:0007618 120 0.080
positive regulation of developmental process GO:0051094 143 0.076
male mating behavior GO:0060179 70 0.073
organelle localization GO:0051640 148 0.069
learning or memory GO:0007611 141 0.067
homeostatic process GO:0042592 199 0.066
transmembrane transport GO:0055085 139 0.064
positive regulation of biosynthetic process GO:0009891 316 0.064
purine nucleotide biosynthetic process GO:0006164 29 0.063
cellular response to dna damage stimulus GO:0006974 223 0.063
nucleotide metabolic process GO:0009117 161 0.062
insulin receptor signaling pathway GO:0008286 25 0.062
nucleobase containing small molecule metabolic process GO:0055086 174 0.061
establishment of localization in cell GO:0051649 402 0.060
multi organism reproductive behavior GO:0044705 121 0.059
neurological system process GO:0050877 358 0.057
mitochondrion organization GO:0007005 65 0.056
kidney development GO:0001822 3 0.056
negative regulation of cell communication GO:0010648 223 0.054
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.054
inorganic cation transmembrane transport GO:0098662 61 0.053
cellular response to peptide GO:1901653 28 0.053
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.052
cellular protein modification process GO:0006464 438 0.050
ribose phosphate metabolic process GO:0019693 145 0.050
positive regulation of macromolecule metabolic process GO:0010604 405 0.050
secretion by cell GO:0032940 101 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.049
positive regulation of phosphate metabolic process GO:0045937 139 0.049
positive regulation of camp metabolic process GO:0030816 8 0.048
aromatic compound catabolic process GO:0019439 166 0.046
cell maturation GO:0048469 144 0.046
cellular response to organonitrogen compound GO:0071417 36 0.046
negative regulation of response to stimulus GO:0048585 258 0.046
notch signaling pathway GO:0007219 120 0.046
purine ribonucleotide metabolic process GO:0009150 145 0.045
regulation of molecular function GO:0065009 217 0.045
regulation of notch signaling pathway GO:0008593 100 0.044
response to nitrogen compound GO:1901698 90 0.044
cellular response to insulin stimulus GO:0032869 28 0.043
spermatid development GO:0007286 98 0.043
nucleoside phosphate metabolic process GO:0006753 162 0.043
regulation of programmed cell death GO:0043067 152 0.043
Worm
generation of precursor metabolites and energy GO:0006091 42 0.042
organophosphate metabolic process GO:0019637 195 0.042
courtship behavior GO:0007619 68 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.042
spermatogenesis GO:0007283 200 0.041
ras protein signal transduction GO:0007265 88 0.041
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.041
cyclic nucleotide metabolic process GO:0009187 28 0.041
monovalent inorganic cation transport GO:0015672 40 0.041
phagocytosis GO:0006909 215 0.041
monocarboxylic acid transport GO:0015718 3 0.040
purine nucleotide metabolic process GO:0006163 146 0.040
regulation of multicellular organism growth GO:0040014 40 0.040
multi multicellular organism process GO:0044706 123 0.040
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.040
proteasomal protein catabolic process GO:0010498 59 0.039
male courtship behavior veined wing generated song production GO:0045433 20 0.039
negative regulation of rna metabolic process GO:0051253 251 0.039
single organism biosynthetic process GO:0044711 206 0.038
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.038
regulation of cyclic nucleotide biosynthetic process GO:0030802 13 0.037
positive regulation of signal transduction GO:0009967 223 0.037
peptidyl threonine phosphorylation GO:0018107 2 0.037
inorganic ion transmembrane transport GO:0098660 73 0.036
protein catabolic process GO:0030163 101 0.035
catabolic process GO:0009056 409 0.035
growth GO:0040007 359 0.035
negative regulation of rna biosynthetic process GO:1902679 240 0.033
small gtpase mediated signal transduction GO:0007264 88 0.033
immune response GO:0006955 246 0.032
regulation of camp metabolic process GO:0030814 12 0.032
multi organism behavior GO:0051705 175 0.032
heterocycle catabolic process GO:0046700 166 0.032
cellular catabolic process GO:0044248 372 0.031
purine containing compound metabolic process GO:0072521 155 0.031
g protein coupled receptor signaling pathway GO:0007186 136 0.030
positive regulation of catalytic activity GO:0043085 118 0.030
organic acid transport GO:0015849 18 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
anatomical structure homeostasis GO:0060249 97 0.030
macromolecule catabolic process GO:0009057 161 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
l amino acid import GO:0043092 2 0.029
nucleoside metabolic process GO:0009116 127 0.029
ribonucleoside catabolic process GO:0042454 112 0.029
positive regulation of cell communication GO:0010647 250 0.028
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.028
transcription from rna polymerase ii promoter GO:0006366 368 0.028
developmental maturation GO:0021700 172 0.028
response to sterol GO:0036314 34 0.028
metal ion transport GO:0030001 74 0.028
negative regulation of cellular biosynthetic process GO:0031327 277 0.028
camera type eye development GO:0043010 4 0.028
actin filament based process GO:0030029 220 0.028
response to bacterium GO:0009617 198 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
ion transmembrane transport GO:0034220 122 0.027
positive regulation of multicellular organismal process GO:0051240 143 0.027
nitrogen compound transport GO:0071705 85 0.027
regulation of gene expression epigenetic GO:0040029 128 0.027
regulation of membrane potential GO:0042391 35 0.026
cell proliferation GO:0008283 299 0.026
organic anion transport GO:0015711 28 0.026
positive regulation of developmental growth GO:0048639 62 0.026
negative regulation of gene expression GO:0010629 387 0.025
peptidyl threonine modification GO:0018210 3 0.025
negative regulation of signal transduction GO:0009968 206 0.025
regulation of purine nucleotide metabolic process GO:1900542 62 0.025
regulation of cellular response to insulin stimulus GO:1900076 17 0.025
cell cycle phase transition GO:0044770 140 0.025
proteolysis GO:0006508 192 0.025
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 9 0.025
nucleoside catabolic process GO:0009164 112 0.025
atp metabolic process GO:0046034 49 0.025
macromolecular complex assembly GO:0065003 256 0.025
chemical homeostasis GO:0048878 92 0.024
regulation of cell development GO:0060284 215 0.024
positive regulation of molecular function GO:0044093 136 0.024
death GO:0016265 284 0.024
Worm
vesicle mediated transport GO:0016192 381 0.024
molting cycle chitin based cuticle GO:0007591 56 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.024
response to alcohol GO:0097305 95 0.024
response to abiotic stimulus GO:0009628 341 0.024
Zebrafish
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.024
cellular response to oxygen containing compound GO:1901701 79 0.024
retina development in camera type eye GO:0060041 4 0.023
cation transport GO:0006812 110 0.023
cellular macromolecule catabolic process GO:0044265 136 0.023
response to alkaloid GO:0043279 26 0.023
cyclic nucleotide biosynthetic process GO:0009190 25 0.023
protein complex biogenesis GO:0070271 201 0.023
potassium ion transport GO:0006813 20 0.023
carboxylic acid transport GO:0046942 18 0.023
regulation of synaptic transmission GO:0050804 69 0.022
imaginal disc derived appendage development GO:0048737 399 0.022
gene silencing GO:0016458 138 0.022
organic substance catabolic process GO:1901575 308 0.022
negative regulation of biosynthetic process GO:0009890 277 0.022
glycosyl compound metabolic process GO:1901657 127 0.021
positive regulation of rna biosynthetic process GO:1902680 266 0.021
regulation of hormone levels GO:0010817 40 0.021
organic acid metabolic process GO:0006082 103 0.021
secretion GO:0046903 109 0.021
positive regulation of cyclic nucleotide metabolic process GO:0030801 9 0.021
body morphogenesis GO:0010171 2 0.020
ribonucleotide catabolic process GO:0009261 109 0.020
chaeta development GO:0022416 97 0.020
organic substance transport GO:0071702 257 0.020
purine ribonucleoside metabolic process GO:0046128 127 0.020
positive regulation of nucleotide metabolic process GO:0045981 55 0.020
carbohydrate derivative catabolic process GO:1901136 118 0.020
hormone metabolic process GO:0042445 33 0.020
taxis GO:0042330 304 0.020
cell division GO:0051301 248 0.020
cortical actin cytoskeleton organization GO:0030866 24 0.020
regulation of intracellular signal transduction GO:1902531 236 0.019
response to oxygen containing compound GO:1901700 200 0.019
multicellular organismal aging GO:0010259 140 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
secondary metabolite biosynthetic process GO:0044550 24 0.019
mitotic nuclear division GO:0007067 213 0.019
spermatid differentiation GO:0048515 114 0.019
regulation of growth GO:0040008 233 0.019
purine nucleoside triphosphate metabolic process GO:0009144 119 0.019
cellular response to nitrogen compound GO:1901699 51 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
mitotic cell cycle phase transition GO:0044772 138 0.019
cellular response to peptide hormone stimulus GO:0071375 28 0.019
protein transport GO:0015031 155 0.019
dna conformation change GO:0071103 105 0.018
fatty acid homeostasis GO:0055089 2 0.018
circulatory system development GO:0072359 82 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
response to glucose GO:0009749 2 0.018
cortical cytoskeleton organization GO:0030865 29 0.018
alpha amino acid metabolic process GO:1901605 20 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
response to hypoxia GO:0001666 53 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
response to other organism GO:0051707 293 0.018
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.017
apoptotic process GO:0006915 159 0.017
Worm
carbohydrate derivative metabolic process GO:1901135 217 0.017
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.017
male gamete generation GO:0048232 201 0.017
regulation of dendrite development GO:0050773 37 0.017
response to decreased oxygen levels GO:0036293 58 0.017
regulation of cell division GO:0051302 72 0.017
cyclic purine nucleotide metabolic process GO:0052652 25 0.017
response to monosaccharide GO:0034284 4 0.017
male courtship behavior veined wing extension GO:0048065 22 0.017
negative regulation of insulin secretion GO:0046676 1 0.017
oxoacid metabolic process GO:0043436 103 0.017
actin polymerization or depolymerization GO:0008154 31 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
nucleus organization GO:0006997 45 0.017
urogenital system development GO:0001655 72 0.017
regulation of cellular component size GO:0032535 98 0.016
response to oxygen levels GO:0070482 59 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
positive regulation of programmed cell death GO:0043068 62 0.016
Worm
nucleotide catabolic process GO:0009166 109 0.016
regulation of transcription regulatory region dna binding GO:2000677 3 0.016
regulation of chromatin silencing GO:0031935 36 0.016
regulation of developmental growth GO:0048638 174 0.016
striated muscle myosin thick filament assembly GO:0071688 3 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
purine containing compound catabolic process GO:0072523 112 0.016
pyridine nucleotide metabolic process GO:0019362 2 0.016
positive regulation of lyase activity GO:0051349 10 0.016
instar larval development GO:0002168 55 0.016
establishment of organelle localization GO:0051656 122 0.016
negative regulation of peptide secretion GO:0002792 1 0.015
positive regulation of gene expression GO:0010628 290 0.015
positive regulation of signaling GO:0023056 243 0.015
l glutamate import GO:0051938 1 0.015
positive regulation of cell migration GO:0030335 2 0.015
regulation of meiosis GO:0040020 3 0.015
cellular carbohydrate catabolic process GO:0044275 2 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
response to organonitrogen compound GO:0010243 75 0.015
olfactory learning GO:0008355 56 0.015
transmission of nerve impulse GO:0019226 12 0.015
glycosyl compound biosynthetic process GO:1901659 3 0.015
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.015
regulation of nucleoside metabolic process GO:0009118 50 0.015
anion transport GO:0006820 41 0.015
oligosaccharide transport GO:0015772 2 0.014
purine nucleoside monophosphate metabolic process GO:0009126 50 0.014
glycosyl compound catabolic process GO:1901658 112 0.014
regulation of organelle organization GO:0033043 196 0.014
cellular protein catabolic process GO:0044257 83 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
intracellular signal transduction GO:0035556 300 0.014
phosphorylation GO:0016310 294 0.014
regulation of lyase activity GO:0051339 14 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
purine ribonucleoside biosynthetic process GO:0046129 3 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
positive regulation of multicellular organism growth GO:0040018 21 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
positive regulation of growth GO:0045927 75 0.014
actin cytoskeleton organization GO:0030036 206 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
regulation of cell death GO:0010941 173 0.014
Worm
protein complex assembly GO:0006461 200 0.014
regulation of circadian rhythm GO:0042752 49 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
epithelial tube morphogenesis GO:0060562 88 0.014
regulation of steroid metabolic process GO:0019218 2 0.013
myotube cell development GO:0014904 3 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
oxidation reduction process GO:0055114 123 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
response to peptide hormone GO:0043434 29 0.013
regulation of apoptotic process GO:0042981 130 0.013
regulation of hydrolase activity GO:0051336 97 0.013
positive regulation of cell projection organization GO:0031346 29 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
striated muscle cell differentiation GO:0051146 90 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
membrane organization GO:0061024 112 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
positive regulation of catabolic process GO:0009896 105 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
nuclear division GO:0000280 332 0.013
peptidyl amino acid modification GO:0018193 105 0.013
energy derivation by oxidation of organic compounds GO:0015980 32 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
cellular response to organic substance GO:0071310 132 0.013
response to hexose GO:0009746 3 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
centrosome localization GO:0051642 14 0.013
organophosphate catabolic process GO:0046434 112 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.013
purine nucleotide catabolic process GO:0006195 109 0.012
renal system development GO:0072001 72 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
cation homeostasis GO:0055080 51 0.012
regulation of translation GO:0006417 56 0.012
regulation of actin cytoskeleton organization GO:0032956 42 0.012
cellular homeostasis GO:0019725 80 0.012
dendrite morphogenesis GO:0048813 199 0.012
cytoskeleton dependent intracellular transport GO:0030705 44 0.012
developmental growth GO:0048589 280 0.012
dopamine receptor signaling pathway GO:0007212 4 0.012
regionalization GO:0003002 416 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
regulation of defense response GO:0031347 102 0.012
hindbrain development GO:0030902 2 0.012
spinal cord development GO:0021510 1 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
organophosphate biosynthetic process GO:0090407 46 0.012
cellular ketone metabolic process GO:0042180 24 0.012
cognition GO:0050890 141 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
negative regulation of cell death GO:0060548 81 0.012
molting cycle GO:0042303 56 0.012
negative regulation of epithelial cell proliferation GO:0050680 4 0.012
camp metabolic process GO:0046058 19 0.012
chromatin organization GO:0006325 207 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
regulation of cellular localization GO:0060341 136 0.012
positive regulation of ras gtpase activity GO:0032320 36 0.012
regulation of cell projection organization GO:0031344 92 0.012
neuromuscular junction development GO:0007528 149 0.012
memory GO:0007613 94 0.011
ommochrome metabolic process GO:0046152 19 0.011
male courtship behavior veined wing vibration GO:0016545 21 0.011
epithelial cell development GO:0002064 274 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
regulation of ion transport GO:0043269 39 0.011
salivary gland morphogenesis GO:0007435 145 0.011
skeletal muscle fiber development GO:0048741 3 0.011
tor signaling GO:0031929 32 0.011
negative regulation of peptide hormone secretion GO:0090278 1 0.011
regulation of anatomical structure size GO:0090066 163 0.011
stem cell differentiation GO:0048863 117 0.011
detection of stimulus involved in sensory perception GO:0050906 92 0.011
multicellular organism growth GO:0035264 46 0.011
wing disc morphogenesis GO:0007472 344 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
axonogenesis GO:0007409 290 0.011
male courtship behavior GO:0008049 63 0.011
ribonucleoside biosynthetic process GO:0042455 3 0.011
heterochromatin organization GO:0070828 25 0.011
eye development GO:0001654 323 0.011
regulation of cell matrix adhesion GO:0001952 1 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
positive regulation of immune system process GO:0002684 68 0.011
positive regulation of lipid metabolic process GO:0045834 4 0.011
positive regulation of cell motility GO:2000147 3 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
positive regulation of notch signaling pathway GO:0045747 34 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
negative regulation of hormone biosynthetic process GO:0032353 1 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
response to ecdysone GO:0035075 34 0.011
dna metabolic process GO:0006259 227 0.011
intracellular transport GO:0046907 228 0.011
defense response GO:0006952 300 0.011
response to anesthetic GO:0072347 9 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
sodium ion transport GO:0006814 22 0.010
regulation of glial cell differentiation GO:0045685 1 0.010
determination of dorsal ventral asymmetry GO:0048262 3 0.010
epithelial cell differentiation GO:0030855 322 0.010
chromosome segregation GO:0007059 157 0.010
axon guidance GO:0007411 233 0.010
regulation of actin filament based process GO:0032970 42 0.010
regulation of neuron differentiation GO:0045664 103 0.010
response to external biotic stimulus GO:0043207 293 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
ribonucleoside monophosphate metabolic process GO:0009161 51 0.010
regulation of behavior GO:0050795 75 0.010
protein modification process GO:0036211 438 0.010
regulation of secretion GO:0051046 44 0.010
regulation of immune system process GO:0002682 176 0.010
sperm individualization GO:0007291 48 0.010

Pdp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.205
disease of cellular proliferation DOID:14566 0 0.035
heart conduction disease DOID:10273 0 0.032
cardiovascular system disease DOID:1287 0 0.032
disease of metabolism DOID:0014667 0 0.027
nervous system disease DOID:863 0 0.027
diabetes mellitus DOID:9351 0 0.022
carbohydrate metabolism disease DOID:0050013 0 0.022
glucose metabolism disease DOID:4194 0 0.022
acquired metabolic disease DOID:0060158 0 0.022
renal tubular transport disease DOID:447 0 0.019
kidney disease DOID:557 0 0.019
urinary system disease DOID:18 0 0.019
musculoskeletal system disease DOID:17 0 0.018
cancer DOID:162 0 0.017
bone disease DOID:0080001 0 0.013
connective tissue disease DOID:65 0 0.013
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011