Drosophila melanogaster

35 known processes

CG6361 (Dmel_CG6361)

CG6361 gene product from transcript CG6361-RA

(Aliases: Dmel\CG6361,c-SP31,SP31)

CG6361 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response to other organism GO:0098542 225 0.888
Fly
innate immune response GO:0045087 144 0.846
regulation of defense response GO:0031347 102 0.753
melanization defense response GO:0035006 45 0.668
immune response GO:0006955 246 0.576
phenol containing compound metabolic process GO:0018958 57 0.575
antibacterial humoral response GO:0019731 44 0.531
secondary metabolic process GO:0019748 75 0.517
positive regulation of defense response GO:0031349 59 0.480
Fly
immune system process GO:0002376 347 0.470
response to bacterium GO:0009617 198 0.451
pigment metabolic process GO:0042440 84 0.439
defense response GO:0006952 300 0.423
response to external biotic stimulus GO:0043207 293 0.387
Fly
melanotic encapsulation of foreign target GO:0035011 30 0.373
defense response to bacterium GO:0042742 178 0.320
response to other organism GO:0051707 293 0.276
Fly
defense response to gram positive bacterium GO:0050830 41 0.271
regulation of secondary metabolic process GO:0043455 7 0.271
regulation of melanization defense response GO:0035007 6 0.249
defense response to gram negative bacterium GO:0050829 94 0.243
regulation of immune system process GO:0002682 176 0.228
regulation of immune response GO:0050776 118 0.222
humoral immune response GO:0006959 117 0.196
Fly
positive regulation of immune system process GO:0002684 68 0.173
Fly
organonitrogen compound metabolic process GO:1901564 318 0.159
Fly
wound healing GO:0042060 75 0.155
cell adhesion involved in heart morphogenesis GO:0061343 12 0.150
response to organic substance GO:0010033 284 0.148
regulation of response to stress GO:0080134 200 0.142
open tracheal system development GO:0007424 204 0.141
hemolymph coagulation GO:0042381 10 0.138
epithelium migration GO:0090132 148 0.134
response to biotic stimulus GO:0009607 294 0.130
Fly
regulation of innate immune response GO:0045088 71 0.129
dorsal ventral pattern formation GO:0009953 133 0.127
melanin metabolic process GO:0006582 47 0.122
negative regulation of gene expression GO:0010629 387 0.119
tracheal outgrowth open tracheal system GO:0007426 18 0.117
negative regulation of defense response GO:0031348 35 0.115
tissue migration GO:0090130 155 0.112
regionalization GO:0003002 416 0.109
small molecule metabolic process GO:0044281 305 0.108
zymogen activation GO:0031638 20 0.107
axis specification GO:0009798 167 0.101
regulation of response to external stimulus GO:0032101 115 0.093
Fly
pattern recognition receptor signaling pathway GO:0002221 2 0.092
regulation of cellular protein metabolic process GO:0032268 243 0.092
regulation of defense response to bacterium GO:1900424 30 0.091
immune effector process GO:0002252 98 0.088
Fly
cell cell signaling involved in cell fate commitment GO:0045168 210 0.087
regulation of antimicrobial peptide production GO:0002784 44 0.084
Fly
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.081
positive regulation of melanization defense response GO:0035008 1 0.080
alpha amino acid metabolic process GO:1901605 20 0.078
positive regulation of response to stimulus GO:0048584 323 0.078
Fly
proteolysis GO:0006508 192 0.077
Fly
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.075
toll signaling pathway GO:0008063 25 0.073
antimicrobial humoral response GO:0019730 99 0.073
Fly
negative regulation of protein metabolic process GO:0051248 85 0.073
regulation of protein metabolic process GO:0051246 256 0.070
respiratory system development GO:0060541 213 0.066
activation of innate immune response GO:0002218 4 0.063
antibacterial peptide production GO:0002778 22 0.063
vesicle mediated transport GO:0016192 381 0.058
response to wounding GO:0009611 94 0.057
positive regulation of antibacterial peptide production GO:0002803 20 0.056
epithelial cell migration GO:0010631 148 0.056
regulation of proteolysis GO:0030162 87 0.056
lateral inhibition GO:0046331 206 0.055
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.054
cellular ketone metabolic process GO:0042180 24 0.053
ocellus pigment metabolic process GO:0046158 19 0.053
regulation of antibacterial peptide production GO:0002786 22 0.052
positive regulation of response to external stimulus GO:0032103 44 0.052
Fly
regulation of multicellular organismal development GO:2000026 414 0.051
dorsal ventral axis specification GO:0009950 66 0.050
positive regulation of signal transduction GO:0009967 223 0.050
taxis GO:0042330 304 0.049
growth GO:0040007 359 0.048
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.048
Fly
cellular response to organic substance GO:0071310 132 0.047
imaginal disc derived wing morphogenesis GO:0007476 337 0.047
cellular amino acid metabolic process GO:0006520 61 0.046
negative regulation of cellular protein metabolic process GO:0032269 85 0.046
protein processing GO:0016485 68 0.046
positive regulation of defense response to bacterium GO:1900426 23 0.046
developmental growth involved in morphogenesis GO:0060560 65 0.045
localization of cell GO:0051674 257 0.045
developmental growth GO:0048589 280 0.044
regulation of transport GO:0051049 181 0.044
antimicrobial peptide production GO:0002775 46 0.043
Fly
establishment of localization in cell GO:0051649 402 0.043
organic acid metabolic process GO:0006082 103 0.043
protein phosphorylation GO:0006468 169 0.043
positive regulation of biosynthetic process GO:0009891 316 0.043
Fly
eye pigmentation GO:0048069 43 0.043
regulation of localization GO:0032879 275 0.042
ocellus pigment biosynthetic process GO:0008055 19 0.041
cellular catabolic process GO:0044248 372 0.040
positive regulation of signaling GO:0023056 243 0.040
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.040
response to fungus GO:0009620 50 0.040
Fly
wing disc morphogenesis GO:0007472 344 0.040
regulation of neuron projection development GO:0010975 69 0.038
embryonic morphogenesis GO:0048598 206 0.038
adult chitin containing cuticle pigmentation GO:0048085 16 0.038
carboxylic acid metabolic process GO:0019752 92 0.038
endocytosis GO:0006897 310 0.037
glycosaminoglycan catabolic process GO:0006027 3 0.037
regulation of molecular function GO:0065009 217 0.037
cell migration GO:0016477 238 0.037
negative regulation of innate immune response GO:0045824 30 0.037
phagocytosis GO:0006909 215 0.037
regulation of response to wounding GO:1903034 19 0.036
oxoacid metabolic process GO:0043436 103 0.036
ameboidal type cell migration GO:0001667 151 0.036
defense response to fungus GO:0050832 48 0.036
Fly
regulation of nervous system development GO:0051960 248 0.035
cellular amine metabolic process GO:0044106 12 0.035
protein maturation GO:0051604 71 0.035
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.035
axon development GO:0061564 297 0.035
axonogenesis GO:0007409 290 0.035
connective tissue development GO:0061448 3 0.035
positive regulation of cellular protein metabolic process GO:0032270 118 0.034
negative regulation of immune system process GO:0002683 50 0.034
regulation of anatomical structure morphogenesis GO:0022603 242 0.034
peptidoglycan metabolic process GO:0000270 3 0.034
regulation of multi organism process GO:0043900 131 0.034
Fly
regulation of cell differentiation GO:0045595 302 0.034
axon guidance GO:0007411 233 0.033
positive regulation of molecular function GO:0044093 136 0.033
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.032
positive regulation of multi organism process GO:0043902 40 0.032
Fly
regulation of mapk cascade GO:0043408 92 0.032
tissue morphogenesis GO:0048729 297 0.032
pigment biosynthetic process GO:0046148 36 0.032
cell motility GO:0048870 251 0.031
neutral lipid biosynthetic process GO:0046460 2 0.031
organophosphate metabolic process GO:0019637 195 0.031
ommochrome metabolic process GO:0046152 19 0.031
positive regulation of immune response GO:0050778 63 0.031
Fly
gene silencing GO:0016458 138 0.031
pigment metabolic process involved in pigmentation GO:0043474 33 0.030
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.030
positive regulation of transport GO:0051050 92 0.030
organic hydroxy compound metabolic process GO:1901615 83 0.030
regulation of neuron differentiation GO:0045664 103 0.030
response to endogenous stimulus GO:0009719 119 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
Fly
photoreceptor cell differentiation GO:0046530 170 0.029
gene silencing by rna GO:0031047 57 0.029
mating GO:0007618 120 0.029
nephron development GO:0072006 3 0.028
epithelial cell migration open tracheal system GO:0007427 32 0.028
response to lipopolysaccharide GO:0032496 4 0.028
cellular modified amino acid metabolic process GO:0006575 45 0.028
developmental pigmentation GO:0048066 68 0.028
compound eye photoreceptor cell differentiation GO:0001751 140 0.028
positive regulation of antimicrobial humoral response GO:0002760 28 0.028
Fly
positive regulation of cell communication GO:0010647 250 0.028
eye photoreceptor cell development GO:0042462 81 0.028
regulation of cell size GO:0008361 63 0.028
embryo development ending in birth or egg hatching GO:0009792 152 0.027
acylglycerol biosynthetic process GO:0046463 2 0.027
amine metabolic process GO:0009308 12 0.027
positive regulation of cell death GO:0010942 69 0.027
embryonic development via the syncytial blastoderm GO:0001700 148 0.026
neuron projection guidance GO:0097485 241 0.026
compound eye development GO:0048749 307 0.026
dendrite development GO:0016358 204 0.026
regulation of cell morphogenesis GO:0022604 163 0.025
catabolic process GO:0009056 409 0.025
cellular protein modification process GO:0006464 438 0.025
body morphogenesis GO:0010171 2 0.025
response to oxygen containing compound GO:1901700 200 0.025
response to organophosphorus GO:0046683 2 0.025
regulation of gene silencing GO:0060968 63 0.025
organic substance catabolic process GO:1901575 308 0.025
regulation of growth GO:0040008 233 0.025
positive regulation of cell migration GO:0030335 2 0.024
single organism catabolic process GO:0044712 228 0.024
cellular response to lipopolysaccharide GO:0071222 3 0.024
chitin based cuticle development GO:0040003 49 0.024
benzene containing compound metabolic process GO:0042537 3 0.024
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.024
response to abiotic stimulus GO:0009628 341 0.024
regulation of anatomical structure size GO:0090066 163 0.024
negative regulation of protein processing GO:0010955 31 0.023
positive regulation of humoral immune response GO:0002922 28 0.023
Fly
regulation of humoral immune response GO:0002920 51 0.023
Fly
negative regulation of proteolysis GO:0045861 31 0.023
encapsulation of foreign target GO:0035010 38 0.023
positive regulation of phosphate metabolic process GO:0045937 139 0.023
negative regulation of developmental process GO:0051093 201 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.022
kidney development GO:0001822 3 0.022
regulation of catalytic activity GO:0050790 185 0.022
cell death GO:0008219 279 0.022
positive regulation of cell motility GO:2000147 3 0.022
chitin based cuticle sclerotization GO:0007593 19 0.022
chromosome segregation GO:0007059 157 0.022
nuclear division GO:0000280 332 0.022
columnar cuboidal epithelial cell development GO:0002066 249 0.022
appendage morphogenesis GO:0035107 397 0.022
cell projection assembly GO:0030031 94 0.022
phosphorylation GO:0016310 294 0.022
stem cell differentiation GO:0048863 117 0.021
regulation of cell development GO:0060284 215 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
positive regulation of response to biotic stimulus GO:0002833 31 0.021
Fly
endomembrane system organization GO:0010256 119 0.021
eye morphogenesis GO:0048592 260 0.021
courtship behavior GO:0007619 68 0.021
nitrogen compound transport GO:0071705 85 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
response to copper ion GO:0046688 4 0.020
innate immune response activating signal transduction GO:0002758 2 0.020
eye development GO:0001654 323 0.020
golgi organization GO:0007030 66 0.020
compound eye photoreceptor development GO:0042051 78 0.020
amide biosynthetic process GO:0043604 42 0.020
Fly
secondary metabolite biosynthetic process GO:0044550 24 0.020
peptide metabolic process GO:0006518 80 0.020
Fly
morphogenesis of an epithelium GO:0002009 276 0.019
chemotaxis GO:0006935 249 0.019
alditol phosphate metabolic process GO:0052646 2 0.019
regulation of transferase activity GO:0051338 58 0.019
regulation of cellular component size GO:0032535 98 0.019
organic substance transport GO:0071702 257 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
cell cell junction assembly GO:0007043 38 0.019
maintenance of location GO:0051235 73 0.019
photoreceptor cell development GO:0042461 96 0.019
pigmentation GO:0043473 75 0.019
regulation of tube architecture open tracheal system GO:0035152 68 0.019
sensory perception of chemical stimulus GO:0007606 116 0.018
segmentation GO:0035282 207 0.018
synaptic transmission GO:0007268 288 0.018
multicellular organismal aging GO:0010259 140 0.018
regulation of toll signaling pathway GO:0008592 17 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
blastoderm segmentation GO:0007350 159 0.018
antibacterial peptide biosynthetic process GO:0002780 22 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
production of molecular mediator of immune response GO:0002440 46 0.018
Fly
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.017
negative regulation of cell differentiation GO:0045596 143 0.017
neurological system process GO:0050877 358 0.017
ommochrome biosynthetic process GO:0006727 19 0.017
appendage development GO:0048736 401 0.017
germ cell migration GO:0008354 43 0.017
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.017
Fly
detection of stimulus GO:0051606 156 0.017
cellular response to endogenous stimulus GO:0071495 80 0.017
regulation of phosphate metabolic process GO:0019220 210 0.017
digestive system development GO:0055123 149 0.017
regulation of cell shape GO:0008360 113 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
developmental maturation GO:0021700 172 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.017
Fly
posttranscriptional regulation of gene expression GO:0010608 145 0.017
protein complex biogenesis GO:0070271 201 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
compound eye morphogenesis GO:0001745 249 0.017
eye photoreceptor cell differentiation GO:0001754 145 0.016
developmental programmed cell death GO:0010623 138 0.016
filopodium assembly GO:0046847 33 0.016
organelle fission GO:0048285 340 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
protein transport GO:0015031 155 0.016
gliogenesis GO:0042063 80 0.016
cellular macromolecular complex assembly GO:0034622 153 0.015
forebrain development GO:0030900 2 0.015
negative regulation of cell development GO:0010721 62 0.015
protein localization GO:0008104 284 0.015
cellular biogenic amine catabolic process GO:0042402 1 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
single organism intracellular transport GO:1902582 207 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
basement membrane organization GO:0071711 10 0.015
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.015
regulation of cell proliferation GO:0042127 163 0.015
regulation of programmed cell death GO:0043067 152 0.015
male meiosis GO:0007140 52 0.015
male courtship behavior GO:0008049 63 0.015
cholesterol homeostasis GO:0042632 3 0.015
regulation of protein processing GO:0070613 32 0.015
protein modification process GO:0036211 438 0.015
peptidyl amino acid modification GO:0018193 105 0.015
lipid storage GO:0019915 38 0.014
ocellus pigmentation GO:0033060 19 0.014
macromolecule catabolic process GO:0009057 161 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
branching involved in open tracheal system development GO:0060446 45 0.014
embryonic pattern specification GO:0009880 174 0.014
anion homeostasis GO:0055081 3 0.014
energy taxis GO:0009453 21 0.014
negative regulation of immune response GO:0050777 39 0.014
hormone catabolic process GO:0042447 3 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
response to organic cyclic compound GO:0014070 89 0.014
cell growth GO:0016049 108 0.014
regulation of tube size open tracheal system GO:0035151 43 0.013
regulation of response to biotic stimulus GO:0002831 63 0.013
Fly
single organism biosynthetic process GO:0044711 206 0.013
protein complex assembly GO:0006461 200 0.013
regulation of cell growth GO:0001558 43 0.013
urogenital system development GO:0001655 72 0.013
regulation of axonogenesis GO:0050770 32 0.013
regulation of protein modification process GO:0031399 112 0.013
regulation of body fluid levels GO:0050878 14 0.013
negative regulation of catalytic activity GO:0043086 42 0.013
intracellular transport GO:0046907 228 0.013
male gamete generation GO:0048232 201 0.013
positive regulation of cellular amide metabolic process GO:0034250 26 0.013
Fly
regulation of phosphorylation GO:0042325 147 0.013
intracellular signal transduction GO:0035556 300 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.012
gland development GO:0048732 191 0.012
antifungal humoral response GO:0019732 12 0.012
Fly
response to oxygen levels GO:0070482 59 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
Fly
indole containing compound biosynthetic process GO:0042435 4 0.012
multi multicellular organism process GO:0044706 123 0.012
glial cell differentiation GO:0010001 35 0.012
locomotory behavior GO:0007626 176 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
regulation of tube size GO:0035150 46 0.012
border follicle cell migration GO:0007298 113 0.012
ion transport GO:0006811 145 0.012
positive regulation of innate immune response GO:0045089 38 0.012
female meiotic division GO:0007143 70 0.012
regulation of wound healing GO:0061041 13 0.012
regulation of chitin based cuticle tanning GO:0007564 14 0.012
regulation of lipid transport GO:0032368 3 0.012
muscle organ development GO:0007517 127 0.012
regulation of chemotaxis GO:0050920 12 0.012
response to radiation GO:0009314 155 0.012
regulation of developmental growth GO:0048638 174 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.012
regulation of locomotion GO:0040012 42 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
cuticle development GO:0042335 86 0.011
negative regulation of signaling GO:0023057 219 0.011
mapk cascade GO:0000165 107 0.011
digestive tract morphogenesis GO:0048546 127 0.011
cell adhesion GO:0007155 136 0.011
death GO:0016265 284 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
cell fate determination GO:0001709 91 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
epiboly involved in wound healing GO:0090505 2 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
embryonic axis specification GO:0000578 107 0.011
synaptic target recognition GO:0008039 45 0.011
wing disc pattern formation GO:0035222 66 0.011
mitotic nuclear division GO:0007067 213 0.011
response to ethanol GO:0045471 59 0.011
oocyte anterior posterior axis specification GO:0007314 72 0.011
glycerolipid catabolic process GO:0046503 3 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
biological adhesion GO:0022610 138 0.011
spindle organization GO:0007051 253 0.011
cell cell junction organization GO:0045216 55 0.011
homeostatic process GO:0042592 199 0.011
cell division GO:0051301 248 0.011
somatic muscle development GO:0007525 66 0.011
rhabdomere development GO:0042052 38 0.011
cellular protein localization GO:0034613 160 0.011
anatomical structure homeostasis GO:0060249 97 0.011
tube development GO:0035295 244 0.011
regulation of neurogenesis GO:0050767 158 0.011
regulation of epithelial cell migration GO:0010632 12 0.011
purine containing compound metabolic process GO:0072521 155 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.010
cuticle pigmentation GO:0048067 22 0.010
cholesterol transport GO:0030301 2 0.010
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.010
carboxylic acid transport GO:0046942 18 0.010
extracellular matrix organization GO:0030198 32 0.010
detection of chemical stimulus GO:0009593 93 0.010
central nervous system development GO:0007417 201 0.010
negative regulation of defense response to bacterium GO:1900425 7 0.010
negative regulation of molecular function GO:0044092 51 0.010
l amino acid import GO:0043092 2 0.010
cell recognition GO:0008037 102 0.010
positive regulation of response to wounding GO:1903036 15 0.010
response to calcium ion GO:0051592 1 0.010
mitotic spindle organization GO:0007052 220 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010

CG6361 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
carbohydrate metabolism disease DOID:0050013 0 0.014
glucose metabolism disease DOID:4194 0 0.014
acquired metabolic disease DOID:0060158 0 0.014
sensory system disease DOID:0050155 0 0.013