Drosophila melanogaster

125 known processes

pho (Dmel_CG17743)

pleiohomeotic

(Aliases: l(4)pho,PHO,CG17743,YY1,dYY1,l(4)BU-2,l(4)29,l(4)OC-1,Pho,l(4)102EFc,Dmel\CG17743)

pho biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dendrite morphogenesis GO:0048813 199 0.984
dendrite development GO:0016358 204 0.964
regulation of gene expression epigenetic GO:0040029 128 0.645
synapse organization GO:0050808 196 0.612
neuromuscular junction development GO:0007528 149 0.587
regulation of localization GO:0032879 275 0.504
camera type eye development GO:0043010 4 0.433
Mouse
chromatin mediated maintenance of transcription GO:0048096 7 0.408
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.349
negative regulation of biosynthetic process GO:0009890 277 0.346
negative regulation of cellular metabolic process GO:0031324 382 0.339
imaginal disc derived appendage development GO:0048737 399 0.329
regulation of multicellular organismal development GO:2000026 414 0.319
appendage morphogenesis GO:0035107 397 0.308
germ line stem cell division GO:0042078 25 0.301
mesenchymal cell differentiation GO:0048762 1 0.278
muscle cell fate commitment GO:0042693 14 0.251
collateral sprouting GO:0048668 3 0.249
axon development GO:0061564 297 0.245
appendage development GO:0048736 401 0.235
chromatin silencing GO:0006342 76 0.232
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.231
regulation of nervous system development GO:0051960 248 0.224
stem cell development GO:0048864 79 0.210
negative regulation of signaling GO:0023057 219 0.207
negative regulation of nucleic acid templated transcription GO:1903507 240 0.206
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.193
growth GO:0040007 359 0.180
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.141
regulation of cellular component biogenesis GO:0044087 201 0.128
negative regulation of cellular biosynthetic process GO:0031327 277 0.122
imaginal disc derived appendage morphogenesis GO:0035114 395 0.116
regulation of cell differentiation GO:0045595 302 0.113
branching morphogenesis of an epithelial tube GO:0048754 45 0.110
single organism intracellular transport GO:1902582 207 0.110
adult locomotory behavior GO:0008344 76 0.104
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.102
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.099
Human Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.097
sex differentiation GO:0007548 81 0.096
Human
synapse assembly GO:0007416 143 0.093
regulation of epithelial cell proliferation GO:0050678 4 0.091
response to organic substance GO:0010033 284 0.090
ras protein signal transduction GO:0007265 88 0.090
negative regulation of developmental process GO:0051093 201 0.087
positive regulation of rna metabolic process GO:0051254 271 0.085
death GO:0016265 284 0.081
protein modification process GO:0036211 438 0.080
positive regulation of phosphate metabolic process GO:0045937 139 0.079
leg disc development GO:0035218 92 0.079
stem cell division GO:0017145 69 0.078
actin cytoskeleton organization GO:0030036 206 0.078
positive regulation of macromolecule metabolic process GO:0010604 405 0.074
stem cell differentiation GO:0048863 117 0.069
developmental growth GO:0048589 280 0.068
negative regulation of response to stimulus GO:0048585 258 0.065
cell proliferation GO:0008283 299 0.064
regulation of cell development GO:0060284 215 0.063
regulation of molecular function GO:0065009 217 0.062
regulation of nucleotide catabolic process GO:0030811 48 0.060
protein localization GO:0008104 284 0.059
negative regulation of signal transduction GO:0009968 206 0.057
negative regulation of transcription dna templated GO:0045892 237 0.057
adult behavior GO:0030534 137 0.057
gene silencing GO:0016458 138 0.057
endocytosis GO:0006897 310 0.054
positive regulation of biosynthetic process GO:0009891 316 0.054
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.053
Human Mouse
programmed cell death GO:0012501 257 0.052
reproductive system development GO:0061458 74 0.052
Human
protein ubiquitination GO:0016567 70 0.050
establishment of localization in cell GO:0051649 402 0.050
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.049
regulation of phosphorus metabolic process GO:0051174 210 0.047
regulation of hemocyte proliferation GO:0035206 37 0.046
regulation of protein localization GO:0032880 76 0.045
eye development GO:0001654 323 0.045
Mouse
cellular response to chemical stimulus GO:0070887 199 0.045
nucleotide catabolic process GO:0009166 109 0.045
small gtpase mediated signal transduction GO:0007264 88 0.045
nucleoside triphosphate catabolic process GO:0009143 108 0.044
ion homeostasis GO:0050801 55 0.044
neuron projection guidance GO:0097485 241 0.042
epithelial tube morphogenesis GO:0060562 88 0.042
neural precursor cell proliferation GO:0061351 75 0.041
oocyte maturation GO:0001556 3 0.041
positive regulation of cellular component organization GO:0051130 156 0.041
regulation of catalytic activity GO:0050790 185 0.041
transcription from rna polymerase ii promoter GO:0006366 368 0.041
Human Mouse
maintenance of location GO:0051235 73 0.040
embryonic organ development GO:0048568 50 0.039
retina development in camera type eye GO:0060041 4 0.039
forebrain development GO:0030900 2 0.039
phagocytosis GO:0006909 215 0.039
negative regulation of rna biosynthetic process GO:1902679 240 0.039
negative regulation of cell communication GO:0010648 223 0.038
negative regulation of epithelial cell proliferation GO:0050680 4 0.037
cellular response to organic substance GO:0071310 132 0.036
tube morphogenesis GO:0035239 191 0.036
regulation of cytoplasmic transport GO:1903649 47 0.036
regulation of axon regeneration GO:0048679 4 0.034
regulation of imaginal disc growth GO:0045570 26 0.034
developmental growth involved in morphogenesis GO:0060560 65 0.034
guanosine containing compound catabolic process GO:1901069 74 0.034
embryo development ending in birth or egg hatching GO:0009792 152 0.034
Mouse
rac protein signal transduction GO:0016601 3 0.034
central nervous system projection neuron axonogenesis GO:0021952 6 0.033
regulation of cellular catabolic process GO:0031329 157 0.033
chromosome organization GO:0051276 360 0.033
positive regulation of nucleic acid templated transcription GO:1903508 266 0.032
regulation of cell proliferation GO:0042127 163 0.032
regulation of synapse assembly GO:0051963 94 0.032
positive regulation of catalytic activity GO:0043085 118 0.030
regulation of hydrolase activity GO:0051336 97 0.030
chemotaxis GO:0006935 249 0.030
nucleocytoplasmic transport GO:0006913 72 0.029
negative regulation of cellular response to growth factor stimulus GO:0090288 6 0.027
dormancy process GO:0022611 2 0.027
cell death GO:0008219 279 0.027
nucleoside catabolic process GO:0009164 112 0.027
positive regulation of gene expression GO:0010628 290 0.026
synaptic growth at neuromuscular junction GO:0051124 119 0.026
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.026
protein modification by small protein conjugation GO:0032446 79 0.026
nucleoside metabolic process GO:0009116 127 0.026
positive regulation of feeding behavior GO:2000253 8 0.025
regulation of small gtpase mediated signal transduction GO:0051056 93 0.025
mesenchymal cell development GO:0014031 1 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
negative regulation of rna metabolic process GO:0051253 251 0.024
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.024
embryonic development via the syncytial blastoderm GO:0001700 148 0.023
positive regulation of catabolic process GO:0009896 105 0.023
neuron remodeling GO:0016322 29 0.023
regulation of dendrite development GO:0050773 37 0.022
purine nucleotide catabolic process GO:0006195 109 0.022
purine nucleoside triphosphate metabolic process GO:0009144 119 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
oxidation reduction process GO:0055114 123 0.021
nucleoside triphosphate metabolic process GO:0009141 120 0.021
regulation of synapse structure and activity GO:0050803 128 0.021
spindle localization GO:0051653 22 0.021
positive regulation of developmental process GO:0051094 143 0.021
development of primary sexual characteristics GO:0045137 50 0.020
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.020
cytoplasmic transport GO:0016482 130 0.020
purine ribonucleoside catabolic process GO:0046130 112 0.020
regulation of ras gtpase activity GO:0032318 38 0.020
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.020
eye antennal disc development GO:0035214 60 0.019
limb development GO:0060173 1 0.019
carbohydrate derivative catabolic process GO:1901136 118 0.019
ubiquitin dependent protein catabolic process GO:0006511 78 0.019
regulation of neuron differentiation GO:0045664 103 0.019
cellular protein modification process GO:0006464 438 0.019
response to carbon dioxide GO:0010037 4 0.019
cellular catabolic process GO:0044248 372 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
negative regulation of cellular component organization GO:0051129 108 0.018
positive regulation of neurogenesis GO:0050769 41 0.018
regulation of programmed cell death GO:0043067 152 0.018
vesicle mediated transport GO:0016192 381 0.018
signal transduction downstream of smoothened GO:0007227 5 0.018
positive regulation of cell projection organization GO:0031346 29 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
imaginal disc growth GO:0007446 37 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
somatic stem cell division GO:0048103 37 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.017
positive regulation of hh target transcription factor activity GO:0007228 5 0.017
taxis GO:0042330 304 0.017
positive regulation of cell development GO:0010720 61 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.016
response to oxygen containing compound GO:1901700 200 0.016
purine containing compound catabolic process GO:0072523 112 0.016
cellular response to carbon dioxide GO:0071244 2 0.016
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 1 0.016
gland development GO:0048732 191 0.015
positive regulation of chromosome segregation GO:0051984 10 0.015
intracellular protein transport GO:0006886 104 0.015
response to bacterium GO:0009617 198 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
cardiovascular system development GO:0072358 82 0.015
heart development GO:0007507 82 0.015
catabolic process GO:0009056 409 0.015
ribonucleoside monophosphate catabolic process GO:0009158 39 0.014
regulation of gene silencing GO:0060968 63 0.014
feeding behavior GO:0007631 50 0.014
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.014
negative regulation of response to oxidative stress GO:1902883 1 0.014
regulation of transport GO:0051049 181 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.014
morphogenesis of a branching epithelium GO:0061138 45 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.014
intracellular signal transduction GO:0035556 300 0.014
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.014
regulation of cell motility GO:2000145 23 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.013
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.013
regulation of locomotion GO:0040012 42 0.013
regulation of glial cell differentiation GO:0045685 1 0.013
macromolecule methylation GO:0043414 45 0.013
regulation of purine nucleotide catabolic process GO:0033121 48 0.013
axonogenesis GO:0007409 290 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
nucleoside monophosphate metabolic process GO:0009123 52 0.013
regulation of dendrite morphogenesis GO:0048814 28 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
apoptotic process GO:0006915 159 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
muscle organ development GO:0007517 127 0.012
stem cell proliferation GO:0072089 88 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
developmental maturation GO:0021700 172 0.012
maternal specification of dorsal ventral axis oocyte germ line encoded GO:0007311 4 0.012
negative regulation of nervous system development GO:0051961 92 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
dna alkylation GO:0006305 4 0.012
regulation of stem cell differentiation GO:2000736 14 0.012
immune system development GO:0002520 57 0.012
organic substance catabolic process GO:1901575 308 0.011
axonal fasciculation GO:0007413 12 0.011
response to growth factor GO:0070848 31 0.011
sensory perception GO:0007600 196 0.011
cytoplasmic microtubule organization GO:0031122 22 0.011
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.011
response to transforming growth factor beta GO:0071559 18 0.011
regulation of cellular localization GO:0060341 136 0.011
cell migration GO:0016477 238 0.011
regulation of cellular component movement GO:0051270 42 0.011
cellular protein catabolic process GO:0044257 83 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
lateral inhibition GO:0046331 206 0.010
response to external biotic stimulus GO:0043207 293 0.010
regulation of neuron projection development GO:0010975 69 0.010
cellular homeostasis GO:0019725 80 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
telencephalon development GO:0021537 2 0.010
positive regulation of binding GO:0051099 4 0.010
tube development GO:0035295 244 0.010

pho disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org