Drosophila melanogaster

33 known processes

spag4 (Dmel_CG6589)

sperm-associated antigen 4

(Aliases: dspag,Dmel\CG6589,giac,Dspag4,CG6589)

spag4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
male gamete generation GO:0048232 201 0.955
spermatogenesis GO:0007283 200 0.934
sperm individualization GO:0007291 48 0.861
cellularization GO:0007349 90 0.770
spermatid development GO:0007286 98 0.730
spermatid differentiation GO:0048515 114 0.616
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.167
positive regulation of macromolecule metabolic process GO:0010604 405 0.124
positive regulation of peptidase activity GO:0010952 29 0.111
regulation of gene expression epigenetic GO:0040029 128 0.103
sensory organ morphogenesis GO:0090596 260 0.085
immune system process GO:0002376 347 0.079
intracellular transport GO:0046907 228 0.078
regulation of protein metabolic process GO:0051246 256 0.077
localization of cell GO:0051674 257 0.077
organelle assembly GO:0070925 198 0.075
locomotory behavior GO:0007626 176 0.074
negative regulation of signaling GO:0023057 219 0.071
neurological system process GO:0050877 358 0.068
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.067
regulation of endopeptidase activity GO:0052548 36 0.066
regulation of anatomical structure morphogenesis GO:0022603 242 0.065
negative regulation of cellular metabolic process GO:0031324 382 0.061
programmed cell death GO:0012501 257 0.060
regulation of catalytic activity GO:0050790 185 0.055
regulation of cellular protein metabolic process GO:0032268 243 0.054
death GO:0016265 284 0.054
single organism membrane fusion GO:0044801 42 0.053
regulation of programmed cell death GO:0043067 152 0.053
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.050
imaginal disc derived appendage development GO:0048737 399 0.050
negative regulation of cell communication GO:0010648 223 0.050
eye morphogenesis GO:0048592 260 0.050
positive regulation of molecular function GO:0044093 136 0.050
photoreceptor cell differentiation GO:0046530 170 0.049
enzyme linked receptor protein signaling pathway GO:0007167 179 0.048
regulation of molecular function GO:0065009 217 0.047
cell death GO:0008219 279 0.046
protein localization GO:0008104 284 0.044
negative regulation of signal transduction GO:0009968 206 0.043
negative regulation of response to stimulus GO:0048585 258 0.043
apoptotic process GO:0006915 159 0.043
regulation of localization GO:0032879 275 0.043
microtubule based movement GO:0007018 51 0.042
negative regulation of rna metabolic process GO:0051253 251 0.042
positive regulation of cellular biosynthetic process GO:0031328 316 0.042
single organism membrane organization GO:0044802 93 0.041
regulation of multi organism process GO:0043900 131 0.041
defense response to other organism GO:0098542 225 0.041
immune response GO:0006955 246 0.040
regulation of multicellular organismal development GO:2000026 414 0.040
response to external biotic stimulus GO:0043207 293 0.039
proteolysis GO:0006508 192 0.039
compound eye morphogenesis GO:0001745 249 0.038
positive regulation of cell communication GO:0010647 250 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.038
regulation of response to stress GO:0080134 200 0.038
regulation of cell death GO:0010941 173 0.038
phosphorylation GO:0016310 294 0.038
negative regulation of rna biosynthetic process GO:1902679 240 0.037
regulation of cellular localization GO:0060341 136 0.037
compound eye development GO:0048749 307 0.037
adult behavior GO:0030534 137 0.036
regulation of apoptotic process GO:0042981 130 0.036
appendage development GO:0048736 401 0.035
developmental programmed cell death GO:0010623 138 0.035
positive regulation of signal transduction GO:0009967 223 0.035
exocrine system development GO:0035272 162 0.035
cellular protein modification process GO:0006464 438 0.034
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.034
membrane organization GO:0061024 112 0.034
sensory perception GO:0007600 196 0.034
eye photoreceptor cell differentiation GO:0001754 145 0.033
positive regulation of cellular protein metabolic process GO:0032270 118 0.033
posttranscriptional regulation of gene expression GO:0010608 145 0.033
microtubule based transport GO:0010970 42 0.033
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
protein modification process GO:0036211 438 0.031
protein maturation GO:0051604 71 0.031
ribonucleoside metabolic process GO:0009119 127 0.031
posttranscriptional gene silencing by rna GO:0035194 45 0.031
negative regulation of gene expression GO:0010629 387 0.031
sperm motility GO:0030317 12 0.031
positive regulation of proteolysis GO:0045862 52 0.030
negative regulation of cellular biosynthetic process GO:0031327 277 0.029
single organism intracellular transport GO:1902582 207 0.029
appendage morphogenesis GO:0035107 397 0.029
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.028
cellular component assembly involved in morphogenesis GO:0010927 151 0.027
regulation of immune system process GO:0002682 176 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.027
negative regulation of biosynthetic process GO:0009890 277 0.027
embryo development ending in birth or egg hatching GO:0009792 152 0.027
vesicle mediated transport GO:0016192 381 0.027
purine containing compound metabolic process GO:0072521 155 0.027
gene silencing GO:0016458 138 0.027
eye development GO:0001654 323 0.027
purine nucleoside metabolic process GO:0042278 127 0.026
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.026
regulation of peptidase activity GO:0052547 39 0.026
cell motility GO:0048870 251 0.026
response to bacterium GO:0009617 198 0.025
glycosyl compound catabolic process GO:1901658 112 0.025
positive regulation of cell death GO:0010942 69 0.025
cellular catabolic process GO:0044248 372 0.025
ribonucleotide metabolic process GO:0009259 145 0.025
cell proliferation GO:0008283 299 0.025
nucleus organization GO:0006997 45 0.025
nucleoside metabolic process GO:0009116 127 0.025
establishment of localization in cell GO:0051649 402 0.025
purine ribonucleoside metabolic process GO:0046128 127 0.025
organic substance catabolic process GO:1901575 308 0.025
negative regulation of transcription dna templated GO:0045892 237 0.024
response to organic substance GO:0010033 284 0.024
regulation of cellular component biogenesis GO:0044087 201 0.024
wnt signaling pathway GO:0016055 98 0.024
glycosyl compound metabolic process GO:1901657 127 0.024
defense response GO:0006952 300 0.024
regionalization GO:0003002 416 0.024
cellular response to chemical stimulus GO:0070887 199 0.024
catabolic process GO:0009056 409 0.024
positive regulation of biosynthetic process GO:0009891 316 0.023
endocytosis GO:0006897 310 0.023
protein catabolic process GO:0030163 101 0.023
developmental growth GO:0048589 280 0.023
regulation of cysteine type endopeptidase activity GO:2000116 27 0.023
embryonic pattern specification GO:0009880 174 0.023
organic substance transport GO:0071702 257 0.023
salivary gland histolysis GO:0035070 88 0.023
endomembrane system organization GO:0010256 119 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
gland development GO:0048732 191 0.022
protein localization to organelle GO:0033365 82 0.022
serotonin uptake GO:0051610 1 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.022
regulation of small gtpase mediated signal transduction GO:0051056 93 0.022
purine nucleotide metabolic process GO:0006163 146 0.021
regulation of hydrolase activity GO:0051336 97 0.021
regulation of cell development GO:0060284 215 0.021
chromosome organization GO:0051276 360 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
nucleoside triphosphate metabolic process GO:0009141 120 0.020
cytoskeleton dependent intracellular transport GO:0030705 44 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
segmentation GO:0035282 207 0.020
protein complex assembly GO:0006461 200 0.020
ribonucleoside triphosphate metabolic process GO:0009199 119 0.020
adult locomotory behavior GO:0008344 76 0.020
salivary gland morphogenesis GO:0007435 145 0.020
hematopoietic progenitor cell differentiation GO:0002244 1 0.020
positive regulation of signaling GO:0023056 243 0.020
positive regulation of catalytic activity GO:0043085 118 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
positive regulation of protein metabolic process GO:0051247 128 0.019
ion transmembrane transport GO:0034220 122 0.019
nucleoside phosphate metabolic process GO:0006753 162 0.019
regulation of organelle organization GO:0033043 196 0.019
single organism behavior GO:0044708 391 0.019
purine nucleoside triphosphate metabolic process GO:0009144 119 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.019
nucleotide metabolic process GO:0009117 161 0.019
positive regulation of hydrolase activity GO:0051345 78 0.019
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
positive regulation of programmed cell death GO:0043068 62 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
organonitrogen compound metabolic process GO:1901564 318 0.018
regulation of proteolysis GO:0030162 87 0.018
lateral inhibition GO:0046331 206 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
male meiosis GO:0007140 52 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
single organism cellular localization GO:1902580 180 0.018
axon development GO:0061564 297 0.017
phagocytosis GO:0006909 215 0.017
sensory perception of sound GO:0007605 56 0.017
cellular macromolecule localization GO:0070727 220 0.017
anterior posterior pattern specification GO:0009952 136 0.017
organophosphate metabolic process GO:0019637 195 0.017
chromatin organization GO:0006325 207 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
axis specification GO:0009798 167 0.017
negative regulation of gene expression epigenetic GO:0045814 77 0.017
cilium organization GO:0044782 41 0.017
intracellular signal transduction GO:0035556 300 0.017
regulation of transport GO:0051049 181 0.017
circadian behavior GO:0048512 76 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
positive regulation of cellular component organization GO:0051130 156 0.016
regulation of developmental growth GO:0048638 174 0.016
central nervous system development GO:0007417 201 0.016
cell projection assembly GO:0030031 94 0.016
response to abiotic stimulus GO:0009628 341 0.016
anterior posterior axis specification embryo GO:0008595 103 0.016
chromatin silencing GO:0006342 76 0.016
camera type eye development GO:0043010 4 0.016
wing disc morphogenesis GO:0007472 344 0.016
regulation of intracellular transport GO:0032386 64 0.016
tube development GO:0035295 244 0.016
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
macromolecular complex assembly GO:0065003 256 0.015
gene silencing by rna GO:0031047 57 0.015
response to other organism GO:0051707 293 0.015
establishment or maintenance of cell polarity GO:0007163 167 0.015
cell maturation GO:0048469 144 0.015
neurotransmitter transport GO:0006836 37 0.015
cellular protein localization GO:0034613 160 0.015
oocyte construction GO:0007308 112 0.015
developmental maturation GO:0021700 172 0.015
cell division GO:0051301 248 0.015
cytoplasmic transport GO:0016482 130 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
monocarboxylic acid transport GO:0015718 3 0.015
posttranscriptional gene silencing GO:0016441 46 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
positive regulation of apoptotic process GO:0043065 47 0.014
positive regulation of endopeptidase activity GO:0010950 26 0.014
regulation of organ morphogenesis GO:2000027 78 0.014
rhythmic process GO:0048511 106 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
establishment of protein localization GO:0045184 163 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
ion transport GO:0006811 145 0.014
regulation of cell cycle GO:0051726 291 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
photoreceptor cell development GO:0042461 96 0.014
axon cargo transport GO:0008088 29 0.014
epithelial cell differentiation GO:0030855 322 0.013
response to biotic stimulus GO:0009607 294 0.013
actin filament organization GO:0007015 126 0.013
small molecule metabolic process GO:0044281 305 0.013
autophagic cell death GO:0048102 83 0.013
protein phosphorylation GO:0006468 169 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
single organism catabolic process GO:0044712 228 0.013
zymogen activation GO:0031638 20 0.013
nucleotide catabolic process GO:0009166 109 0.013
heterocycle catabolic process GO:0046700 166 0.013
regulation of gene silencing GO:0060968 63 0.013
rna interference GO:0016246 27 0.013
nucleoside catabolic process GO:0009164 112 0.013
negative regulation of defense response GO:0031348 35 0.013
ras protein signal transduction GO:0007265 88 0.013
organelle fusion GO:0048284 46 0.012
growth GO:0040007 359 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.012
nucleoside monophosphate metabolic process GO:0009123 52 0.012
protein complex biogenesis GO:0070271 201 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
negative regulation of immune response GO:0050777 39 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
protein transport GO:0015031 155 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
activation of cysteine type endopeptidase activity GO:0097202 17 0.012
dorsal closure GO:0007391 79 0.012
innate immune response GO:0045087 144 0.012
gland morphogenesis GO:0022612 145 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
regulation of cell differentiation GO:0045595 302 0.012
regulation of immune response GO:0050776 118 0.012
regulation of embryonic development GO:0045995 68 0.012
anterior posterior axis specification GO:0009948 109 0.011
translation GO:0006412 69 0.011
protein dna complex subunit organization GO:0071824 86 0.011
aromatic compound catabolic process GO:0019439 166 0.011
tissue death GO:0016271 102 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
purine containing compound catabolic process GO:0072523 112 0.011
response to oxygen containing compound GO:1901700 200 0.011
kidney development GO:0001822 3 0.011
mitochondrion organization GO:0007005 65 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
regulation of chromatin silencing GO:0031935 36 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
histolysis GO:0007559 102 0.011
oocyte differentiation GO:0009994 145 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
regulation of catabolic process GO:0009894 170 0.011
defense response to bacterium GO:0042742 178 0.011
positive regulation of gene expression GO:0010628 290 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
positive regulation of catabolic process GO:0009896 105 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
regulation of actin cytoskeleton organization GO:0032956 42 0.010
purine ribonucleotide catabolic process GO:0009154 109 0.010
dephosphorylation GO:0016311 51 0.010
erbb signaling pathway GO:0038127 58 0.010
rna processing GO:0006396 147 0.010
eye photoreceptor cell development GO:0042462 81 0.010
purine nucleoside monophosphate metabolic process GO:0009126 50 0.010
blastoderm segmentation GO:0007350 159 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010

spag4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.016
central nervous system disease DOID:331 0 0.015