Drosophila melanogaster

32 known processes

His3.3B (Dmel_CG8989)

Histone H3.3B

(Aliases: CG8989,Dmel\CG8989,His3.3,anon-EST:fe1B6,PH3,dH3.3B,H3.3,HisH3-3Q,H3.3B)

His3.3B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin assembly GO:0031497 48 0.437
Human
nucleosome organization GO:0034728 59 0.434
Human
regulation of rna splicing GO:0043484 69 0.426
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.396
nucleosome assembly GO:0006334 35 0.349
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.330
chromosome organization GO:0051276 360 0.318
Human
programmed cell death GO:0012501 257 0.288
cell division GO:0051301 248 0.238
regulation of mrna splicing via spliceosome GO:0048024 64 0.231
rna splicing via transesterification reactions GO:0000375 73 0.228
regulation of protein metabolic process GO:0051246 256 0.193
positive regulation of proteolysis GO:0045862 52 0.178
cell death GO:0008219 279 0.170
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.163
gland morphogenesis GO:0022612 145 0.162
meiotic cell cycle GO:0051321 171 0.157
protein complex assembly GO:0006461 200 0.154
Human
salivary gland development GO:0007431 162 0.152
dna packaging GO:0006323 91 0.147
Human
nuclear division GO:0000280 332 0.147
alternative mrna splicing via spliceosome GO:0000380 60 0.147
positive regulation of protein metabolic process GO:0051247 128 0.144
apoptotic process GO:0006915 159 0.138
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.128
death GO:0016265 284 0.127
mrna splicing via spliceosome GO:0000398 73 0.119
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.118
rna processing GO:0006396 147 0.112
regulation of catalytic activity GO:0050790 185 0.108
organelle fission GO:0048285 340 0.108
regulation of mrna processing GO:0050684 71 0.108
chromatin organization GO:0006325 207 0.108
Human
cellular macromolecular complex assembly GO:0034622 153 0.099
Human
positive regulation of endopeptidase activity GO:0010950 26 0.099
regulation of cell cycle GO:0051726 291 0.096
protein modification process GO:0036211 438 0.093
salivary gland morphogenesis GO:0007435 145 0.087
regulation of cellular protein metabolic process GO:0032268 243 0.082
retina development in camera type eye GO:0060041 4 0.081
macromolecular complex assembly GO:0065003 256 0.080
Human
activation of cysteine type endopeptidase activity GO:0097202 17 0.080
rna splicing GO:0008380 83 0.079
spermatogenesis GO:0007283 200 0.073
developmental programmed cell death GO:0010623 138 0.071
body morphogenesis GO:0010171 2 0.070
regulation of gene expression epigenetic GO:0040029 128 0.069
positive regulation of cellular protein metabolic process GO:0032270 118 0.069
mrna processing GO:0006397 104 0.068
positive regulation of peptidase activity GO:0010952 29 0.065
histolysis GO:0007559 102 0.064
negative regulation of cellular component organization GO:0051129 108 0.064
regulation of dna metabolic process GO:0051052 34 0.063
gland development GO:0048732 191 0.062
autophagic cell death GO:0048102 83 0.061
vesicle mediated transport GO:0016192 381 0.060
tissue death GO:0016271 102 0.060
homeostatic process GO:0042592 199 0.059
positive regulation of response to stimulus GO:0048584 323 0.058
regulation of molecular function GO:0065009 217 0.058
dephosphorylation GO:0016311 51 0.056
cellular catabolic process GO:0044248 372 0.055
negative regulation of rna metabolic process GO:0051253 251 0.055
negative regulation of gene expression GO:0010629 387 0.055
male meiosis GO:0007140 52 0.054
regulation of response to stress GO:0080134 200 0.052
regulation of synapse structure and activity GO:0050803 128 0.052
embryo development ending in birth or egg hatching GO:0009792 152 0.052
organelle assembly GO:0070925 198 0.052
regulation of mitotic cell cycle GO:0007346 190 0.051
organelle localization GO:0051640 148 0.051
positive regulation of developmental process GO:0051094 143 0.050
cellular protein modification process GO:0006464 438 0.050
imaginal disc derived appendage morphogenesis GO:0035114 395 0.050
post embryonic appendage morphogenesis GO:0035120 385 0.050
regulation of endopeptidase activity GO:0052548 36 0.047
establishment of localization in cell GO:0051649 402 0.047
ubiquitin homeostasis GO:0010992 1 0.046
response to oxygen containing compound GO:1901700 200 0.045
cellular homeostasis GO:0019725 80 0.045
regulation of mrna metabolic process GO:1903311 72 0.045
protein complex biogenesis GO:0070271 201 0.044
Human
nucleotide catabolic process GO:0009166 109 0.044
protein dna complex subunit organization GO:0071824 86 0.043
Human
cellular response to dna damage stimulus GO:0006974 223 0.043
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.042
nucleobase containing small molecule metabolic process GO:0055086 174 0.041
mitotic cell cycle phase transition GO:0044772 138 0.041
synaptic growth at neuromuscular junction GO:0051124 119 0.041
regulation of protein modification process GO:0031399 112 0.041
nucleoside phosphate metabolic process GO:0006753 162 0.040
camera type eye development GO:0043010 4 0.040
actin cytoskeleton organization GO:0030036 206 0.040
synapse organization GO:0050808 196 0.040
positive regulation of cellular component organization GO:0051130 156 0.040
catabolic process GO:0009056 409 0.040
translation GO:0006412 69 0.040
cellular macromolecule localization GO:0070727 220 0.040
regulation of cysteine type endopeptidase activity GO:2000116 27 0.040
salivary gland cell autophagic cell death GO:0035071 83 0.040
exocrine system development GO:0035272 162 0.039
regulation of meiosis GO:0040020 3 0.039
regulation of anatomical structure morphogenesis GO:0022603 242 0.039
phagocytosis GO:0006909 215 0.038
histone exchange GO:0043486 21 0.038
regulation of cell shape GO:0008360 113 0.038
locomotory behavior GO:0007626 176 0.037
determination of adult lifespan GO:0008340 137 0.037
imaginal disc derived appendage development GO:0048737 399 0.037
mrna metabolic process GO:0016071 124 0.036
regulation of organelle organization GO:0033043 196 0.036
cellular protein localization GO:0034613 160 0.036
imaginal disc derived wing morphogenesis GO:0007476 337 0.036
chromatin assembly or disassembly GO:0006333 52 0.035
Human
positive regulation of phosphorylation GO:0042327 87 0.035
protein ubiquitination GO:0016567 70 0.035
ribonucleotide metabolic process GO:0009259 145 0.035
dna metabolic process GO:0006259 227 0.034
Human
regulation of cell division GO:0051302 72 0.034
single organism intracellular transport GO:1902582 207 0.034
autophagy GO:0006914 108 0.034
response to hexose GO:0009746 3 0.034
regulation of cell cycle process GO:0010564 181 0.033
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.033
regulation of proteolysis GO:0030162 87 0.033
ribonucleoside metabolic process GO:0009119 127 0.032
multicellular organismal aging GO:0010259 140 0.032
positive regulation of hydrolase activity GO:0051345 78 0.031
regulation of cell morphogenesis GO:0022604 163 0.031
regulation of phosphorus metabolic process GO:0051174 210 0.031
regulation of transport GO:0051049 181 0.030
purine ribonucleotide metabolic process GO:0009150 145 0.030
regulation of apoptotic process GO:0042981 130 0.030
intracellular transport GO:0046907 228 0.030
organic substance catabolic process GO:1901575 308 0.030
regulation of nuclear division GO:0051783 58 0.030
negative regulation of protein metabolic process GO:0051248 85 0.029
meiotic nuclear division GO:0007126 151 0.029
cytoplasmic transport GO:0016482 130 0.029
regulation of phosphate metabolic process GO:0019220 210 0.029
salivary gland histolysis GO:0035070 88 0.029
protein localization GO:0008104 284 0.028
single organism catabolic process GO:0044712 228 0.028
purine nucleoside catabolic process GO:0006152 112 0.028
positive regulation of signaling GO:0023056 243 0.028
mitotic spindle organization GO:0007052 220 0.027
cellular response to chemical stimulus GO:0070887 199 0.027
dna conformation change GO:0071103 105 0.027
Human
cellular nitrogen compound catabolic process GO:0044270 165 0.027
establishment of organelle localization GO:0051656 122 0.027
response to glucose GO:0009749 2 0.027
response to organic substance GO:0010033 284 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.027
response to monosaccharide GO:0034284 4 0.027
regulation of cellular ketone metabolic process GO:0010565 3 0.026
intracellular signal transduction GO:0035556 300 0.026
spindle organization GO:0007051 253 0.026
positive regulation of programmed cell death GO:0043068 62 0.026
response to alcohol GO:0097305 95 0.026
positive regulation of protein modification process GO:0031401 58 0.026
guanosine containing compound catabolic process GO:1901069 74 0.026
epithelial cell differentiation GO:0030855 322 0.026
appendage morphogenesis GO:0035107 397 0.025
forebrain development GO:0030900 2 0.025
cell maturation GO:0048469 144 0.024
cell adhesion GO:0007155 136 0.024
positive regulation of phosphorus metabolic process GO:0010562 139 0.024
regulation of intracellular signal transduction GO:1902531 236 0.024
nucleotide metabolic process GO:0009117 161 0.024
male gamete generation GO:0048232 201 0.024
posttranscriptional regulation of gene expression GO:0010608 145 0.024
appendage development GO:0048736 401 0.024
heterocycle catabolic process GO:0046700 166 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
regulation of nervous system development GO:0051960 248 0.024
ovarian follicle cell development GO:0030707 248 0.024
aging GO:0007568 143 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
regulation of cell differentiation GO:0045595 302 0.024
positive regulation of cell death GO:0010942 69 0.024
regulation of cellular localization GO:0060341 136 0.023
organonitrogen compound metabolic process GO:1901564 318 0.023
ribonucleoside catabolic process GO:0042454 112 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.022
proteolysis GO:0006508 192 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.022
negative regulation of programmed cell death GO:0043069 72 0.022
response to biotic stimulus GO:0009607 294 0.022
chemotaxis GO:0006935 249 0.022
regulation of phosphorylation GO:0042325 147 0.022
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.022
purine containing compound catabolic process GO:0072523 112 0.022
glycosyl compound metabolic process GO:1901657 127 0.022
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
endocytosis GO:0006897 310 0.021
protein transport GO:0015031 155 0.021
biological adhesion GO:0022610 138 0.021
phosphorylation GO:0016310 294 0.021
aromatic compound catabolic process GO:0019439 166 0.021
response to radiation GO:0009314 155 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
muscle organ development GO:0007517 127 0.020
atp catabolic process GO:0006200 38 0.020
nucleoside triphosphate catabolic process GO:0009143 108 0.020
renal system process GO:0003014 12 0.020
cell cycle phase transition GO:0044770 140 0.019
macromolecule catabolic process GO:0009057 161 0.019
positive regulation of cell communication GO:0010647 250 0.019
cytokinesis GO:0000910 90 0.019
cell proliferation GO:0008283 299 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
establishment of protein localization GO:0045184 163 0.019
protein maturation GO:0051604 71 0.019
meiotic cell cycle process GO:1903046 132 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
ribonucleotide catabolic process GO:0009261 109 0.018
regulation of cell death GO:0010941 173 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
mitotic nuclear division GO:0007067 213 0.018
positive regulation of cellular component biogenesis GO:0044089 80 0.018
regulation of protein phosphorylation GO:0001932 64 0.018
negative regulation of cell death GO:0060548 81 0.018
regulation of synapse assembly GO:0051963 94 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
modification dependent macromolecule catabolic process GO:0043632 79 0.017
regulation of programmed cell death GO:0043067 152 0.017
circulatory system development GO:0072359 82 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.017
double strand break repair GO:0006302 26 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
microtubule organizing center organization GO:0031023 168 0.017
regulation of peptidase activity GO:0052547 39 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
wing disc morphogenesis GO:0007472 344 0.017
actin filament based process GO:0030029 220 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.016
dendrite development GO:0016358 204 0.016
detection of abiotic stimulus GO:0009582 66 0.016
protein catabolic process GO:0030163 101 0.016
nucleoside metabolic process GO:0009116 127 0.016
regulation of hydrolase activity GO:0051336 97 0.016
regulation of synapse organization GO:0050807 110 0.016
ribonucleoside triphosphate catabolic process GO:0009203 108 0.016
protein dna complex assembly GO:0065004 63 0.016
Human
protein phosphorylation GO:0006468 169 0.016
gonad development GO:0008406 50 0.016
cellular response to ethanol GO:0071361 4 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
zymogen activation GO:0031638 20 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
positive regulation of signal transduction GO:0009967 223 0.015
protein modification by small protein conjugation GO:0032446 79 0.015
oenocyte development GO:0007438 8 0.015
cellular protein complex assembly GO:0043623 71 0.015
regulation of catabolic process GO:0009894 170 0.015
eye development GO:0001654 323 0.015
g1 s transition of mitotic cell cycle GO:0000082 31 0.015
regulation of growth GO:0040008 233 0.015
Human
gtp catabolic process GO:0006184 72 0.015
macromolecule methylation GO:0043414 45 0.015
negative regulation of developmental process GO:0051093 201 0.015
positive regulation of apoptotic process GO:0043065 47 0.015
regulation of cell cycle phase transition GO:1901987 130 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
growth GO:0040007 359 0.015
Human
developmental maturation GO:0021700 172 0.014
negative regulation of signal transduction GO:0009968 206 0.014
response to external biotic stimulus GO:0043207 293 0.014
positive regulation of organelle organization GO:0010638 65 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
organophosphate metabolic process GO:0019637 195 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
protein processing GO:0016485 68 0.014
regulation of transferase activity GO:0051338 58 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
eye antennal disc development GO:0035214 60 0.014
chromosome segregation GO:0007059 157 0.013
positive regulation of molecular function GO:0044093 136 0.013
regulation of notch signaling pathway GO:0008593 100 0.013
head development GO:0060322 135 0.013
cellularization GO:0007349 90 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
chemical homeostasis GO:0048878 92 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
positive regulation of intracellular transport GO:0032388 42 0.013
protein methylation GO:0006479 43 0.013
segmentation GO:0035282 207 0.013
cellular amine metabolic process GO:0044106 12 0.013
regulation of chromatin modification GO:1903308 28 0.013
organophosphate catabolic process GO:0046434 112 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
single organism cellular localization GO:1902580 180 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
cell motility GO:0048870 251 0.013
amine metabolic process GO:0009308 12 0.012
rna interference GO:0016246 27 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
chromatin modification GO:0016568 147 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
regulation of cellular response to stress GO:0080135 89 0.012
dendrite morphogenesis GO:0048813 199 0.012
larval development GO:0002164 104 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
gtp metabolic process GO:0046039 72 0.012
positive regulation of protein transport GO:0051222 37 0.012
cellular response to organic substance GO:0071310 132 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
response to other organism GO:0051707 293 0.012
negative regulation of cell communication GO:0010648 223 0.012
regulation of cell proliferation GO:0042127 163 0.012
response to oxidative stress GO:0006979 86 0.012
carbohydrate metabolic process GO:0005975 82 0.012
cellular response to radiation GO:0071478 52 0.011
regulation of localization GO:0032879 275 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
sex differentiation GO:0007548 81 0.011
nuclear transport GO:0051169 72 0.011
protein k48 linked ubiquitination GO:0070936 3 0.011
positive regulation of transport GO:0051050 92 0.011
regulation of mapk cascade GO:0043408 92 0.011
cellular response to monosaccharide stimulus GO:0071326 2 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
histone modification GO:0016570 106 0.011
germarium derived egg chamber formation GO:0007293 101 0.011
stem cell differentiation GO:0048863 117 0.011
regulation of multi organism process GO:0043900 131 0.011
chromatin silencing GO:0006342 76 0.011
regulation of protein localization GO:0032880 76 0.011
ribosomal large subunit biogenesis GO:0042273 1 0.011
stem cell development GO:0048864 79 0.011
phagosome acidification GO:0090383 1 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.010
regulation of intracellular protein transport GO:0033157 46 0.010
posttranscriptional gene silencing GO:0016441 46 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.010
positive regulation of cell migration GO:0030335 2 0.010
organic substance transport GO:0071702 257 0.010
notch signaling pathway GO:0007219 120 0.010
compound eye development GO:0048749 307 0.010
signal transduction by phosphorylation GO:0023014 107 0.010

His3.3B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016