Drosophila melanogaster

0 known processes

S2P (Dmel_CG8988)

site-2 protease

(Aliases: CG8988,anon-WO0118547.346,ds2p,Dmel\CG8988,dS2P)

S2P biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification process GO:0036211 438 0.077
cellular protein modification process GO:0006464 438 0.069
organonitrogen compound metabolic process GO:1901564 318 0.056
negative regulation of response to stimulus GO:0048585 258 0.048
single organism behavior GO:0044708 391 0.047
growth GO:0040007 359 0.042
proteolysis GO:0006508 192 0.041
small molecule metabolic process GO:0044281 305 0.040
organic acid metabolic process GO:0006082 103 0.039
xenobiotic catabolic process GO:0042178 1 0.038
defense response to bacterium GO:0042742 178 0.037
cellular catabolic process GO:0044248 372 0.036
single organism catabolic process GO:0044712 228 0.034
oxoacid metabolic process GO:0043436 103 0.033
positive regulation of response to stimulus GO:0048584 323 0.033
positive regulation of cell communication GO:0010647 250 0.032
positive regulation of signaling GO:0023056 243 0.032
negative regulation of cell cycle process GO:0010948 109 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.029
organic substance catabolic process GO:1901575 308 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
carboxylic acid metabolic process GO:0019752 92 0.026
response to other organism GO:0051707 293 0.025
chemical homeostasis GO:0048878 92 0.025
defense response GO:0006952 300 0.025
positive regulation of signal transduction GO:0009967 223 0.025
regulation of proteolysis GO:0030162 87 0.024
single organism intracellular transport GO:1902582 207 0.024
carbohydrate derivative catabolic process GO:1901136 118 0.024
locomotory behavior GO:0007626 176 0.024
purine ribonucleoside metabolic process GO:0046128 127 0.023
regulation of cell cycle GO:0051726 291 0.023
response to organic substance GO:0010033 284 0.023
cellular amino acid metabolic process GO:0006520 61 0.022
intracellular transport GO:0046907 228 0.022
heterocycle catabolic process GO:0046700 166 0.022
regulation of phosphate metabolic process GO:0019220 210 0.021
regionalization GO:0003002 416 0.021
purine nucleoside catabolic process GO:0006152 112 0.021
cellular amine metabolic process GO:0044106 12 0.021
response to external biotic stimulus GO:0043207 293 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
mitotic dna integrity checkpoint GO:0044774 75 0.021
defense response to other organism GO:0098542 225 0.021
synaptic transmission GO:0007268 288 0.021
ion transport GO:0006811 145 0.021
cellular macromolecule catabolic process GO:0044265 136 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
negative regulation of signal transduction GO:0009968 206 0.020
macromolecule catabolic process GO:0009057 161 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
purine nucleotide catabolic process GO:0006195 109 0.020
negative regulation of cell communication GO:0010648 223 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
ubiquitin dependent protein catabolic process GO:0006511 78 0.020
forebrain development GO:0030900 2 0.020
cellular protein catabolic process GO:0044257 83 0.020
nucleoside catabolic process GO:0009164 112 0.020
guanosine containing compound metabolic process GO:1901068 74 0.019
single organism biosynthetic process GO:0044711 206 0.019
vesicle mediated transport GO:0016192 381 0.019
carbohydrate metabolic process GO:0005975 82 0.019
organophosphate metabolic process GO:0019637 195 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
appendage morphogenesis GO:0035107 397 0.019
negative regulation of signaling GO:0023057 219 0.019
nucleoside phosphate catabolic process GO:1901292 110 0.019
homeostatic process GO:0042592 199 0.019
chromatin organization GO:0006325 207 0.019
multi organism behavior GO:0051705 175 0.019
neurological system process GO:0050877 358 0.019
nucleotide catabolic process GO:0009166 109 0.019
purine containing compound catabolic process GO:0072523 112 0.019
regulation of catalytic activity GO:0050790 185 0.019
organic substance transport GO:0071702 257 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.018
hormone catabolic process GO:0042447 3 0.018
cellular homeostasis GO:0019725 80 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
chaeta development GO:0022416 97 0.018
intracellular signal transduction GO:0035556 300 0.018
guanosine containing compound catabolic process GO:1901069 74 0.018
protein catabolic process GO:0030163 101 0.018
sensory organ morphogenesis GO:0090596 260 0.018
taxis GO:0042330 304 0.018
carbohydrate derivative biosynthetic process GO:1901137 85 0.018
innate immune response GO:0045087 144 0.018
positive regulation of apoptotic signaling pathway GO:2001235 4 0.017
ion transmembrane transport GO:0034220 122 0.017
detection of stimulus involved in sensory perception GO:0050906 92 0.017
cation transport GO:0006812 110 0.017
organophosphate catabolic process GO:0046434 112 0.017
catabolic process GO:0009056 409 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
compound eye development GO:0048749 307 0.017
modification dependent protein catabolic process GO:0019941 78 0.017
purine containing compound metabolic process GO:0072521 155 0.017
immune system process GO:0002376 347 0.017
ras protein signal transduction GO:0007265 88 0.016
telencephalon development GO:0021537 2 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
response to bacterium GO:0009617 198 0.016
phagocytosis GO:0006909 215 0.016
regulation of programmed cell death GO:0043067 152 0.016
organelle fission GO:0048285 340 0.016
appendage development GO:0048736 401 0.016
regulation of behavior GO:0050795 75 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
modification dependent macromolecule catabolic process GO:0043632 79 0.016
amine metabolic process GO:0009308 12 0.016
purine nucleotide metabolic process GO:0006163 146 0.015
regulation of organelle organization GO:0033043 196 0.015
developmental growth GO:0048589 280 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
response to nutrient levels GO:0031667 114 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
dna metabolic process GO:0006259 227 0.015
regulation of protein modification process GO:0031399 112 0.015
oocyte axis specification GO:0007309 108 0.015
compound eye morphogenesis GO:0001745 249 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
mitotic nuclear division GO:0007067 213 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
organelle localization GO:0051640 148 0.015
protein heterooligomerization GO:0051291 4 0.015
regulation of molecular function GO:0065009 217 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
ribose phosphate metabolic process GO:0019693 145 0.014
anion homeostasis GO:0055081 3 0.014
defense response to gram negative bacterium GO:0050829 94 0.014
cellular ketone metabolic process GO:0042180 24 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
nucleoside metabolic process GO:0009116 127 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
phosphorylation GO:0016310 294 0.014
gtp metabolic process GO:0046039 72 0.014
wing disc morphogenesis GO:0007472 344 0.014
regulation of protein metabolic process GO:0051246 256 0.014
mitotic cell cycle checkpoint GO:0007093 88 0.014
gene silencing GO:0016458 138 0.014
death GO:0016265 284 0.014
open tracheal system development GO:0007424 204 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
monocarboxylic acid transport GO:0015718 3 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
dorsal ventral axis specification GO:0009950 66 0.013
extrinsic apoptotic signaling pathway GO:0097191 1 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
chromosome organization GO:0051276 360 0.013
cytoplasmic transport GO:0016482 130 0.013
ion homeostasis GO:0050801 55 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
metal ion homeostasis GO:0055065 44 0.012
response to biotic stimulus GO:0009607 294 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
protein transport GO:0015031 155 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
eye morphogenesis GO:0048592 260 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
cell aging GO:0007569 2 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
nucleotide metabolic process GO:0009117 161 0.012
cell death GO:0008219 279 0.012
eye development GO:0001654 323 0.012
regulation of phosphorylation GO:0042325 147 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
mitotic dna damage checkpoint GO:0044773 74 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
regulation of hydrolase activity GO:0051336 97 0.012
response to abiotic stimulus GO:0009628 341 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
inositol lipid mediated signaling GO:0048017 4 0.011
covalent chromatin modification GO:0016569 106 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
cation homeostasis GO:0055080 51 0.011
developmental pigmentation GO:0048066 68 0.011
spindle organization GO:0007051 253 0.011
nuclear division GO:0000280 332 0.011
axis specification GO:0009798 167 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
establishment of protein localization GO:0045184 163 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
response to oxygen containing compound GO:1901700 200 0.011
cellular macromolecule localization GO:0070727 220 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
regulation of innate immune response GO:0045088 71 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
glycoprotein metabolic process GO:0009100 41 0.011
transmembrane transport GO:0055085 139 0.011
glycoprotein biosynthetic process GO:0009101 41 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
pigment metabolic process involved in pigmentation GO:0043474 33 0.011
cell proliferation GO:0008283 299 0.011
protein phosphorylation GO:0006468 169 0.010
regulation of catabolic process GO:0009894 170 0.010
positive regulation of molecular function GO:0044093 136 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.010
cellular response to chemical stimulus GO:0070887 199 0.010
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
establishment of organelle localization GO:0051656 122 0.010
sensory perception of chemical stimulus GO:0007606 116 0.010
negative regulation of cell cycle phase transition GO:1901988 103 0.010
negative regulation of epithelial cell proliferation GO:0050680 4 0.010
vitamin biosynthetic process GO:0009110 1 0.010
regulation of cell differentiation GO:0045595 302 0.010
rhythmic behavior GO:0007622 76 0.010

S2P disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
disease of cellular proliferation DOID:14566 0 0.024
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.015
nervous system disease DOID:863 0 0.014