Drosophila melanogaster

29 known processes

tam (Dmel_CG8987)

tamas

(Aliases: anon-34Dc,l(2)br5,Dmel\CG8987,l(2)34Dc,polgamma-alpha,MtPolA,pol gamma-alpha,l(2)br14,BG:DS00941.6,Polgamma,pol gamma,br5,CG8987,mtPolA,DNApol-gamma,polgamma,D-pol gamma-alpha,l(2)brS,DNApol-gamma125,34Dc,mtDNA pol,Tam,AAC47658,cDNA 2)

tam biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neurological system process GO:0050877 358 0.353
cellular protein modification process GO:0006464 438 0.309
single organism behavior GO:0044708 391 0.231
taxis GO:0042330 304 0.223
axonogenesis GO:0007409 290 0.215
ion transport GO:0006811 145 0.205
locomotory behavior GO:0007626 176 0.193
response to abiotic stimulus GO:0009628 341 0.173
axon guidance GO:0007411 233 0.123
chemotaxis GO:0006935 249 0.121
small molecule metabolic process GO:0044281 305 0.115
sensory perception GO:0007600 196 0.105
positive regulation of molecular function GO:0044093 136 0.104
regulation of growth GO:0040008 233 0.104
immune system process GO:0002376 347 0.103
negative regulation of cellular metabolic process GO:0031324 382 0.098
mitochondrion organization GO:0007005 65 0.092
Mouse Worm
regulation of nervous system development GO:0051960 248 0.090
lateral inhibition GO:0046331 206 0.090
cuticle pigmentation GO:0048067 22 0.083
molting cycle chitin based cuticle GO:0007591 56 0.083
axon development GO:0061564 297 0.076
molting cycle process GO:0022404 29 0.075
chromosome organization GO:0051276 360 0.075
organonitrogen compound metabolic process GO:1901564 318 0.075
protein modification by small protein conjugation or removal GO:0070647 106 0.073
regulation of molecular function GO:0065009 217 0.073
gravitaxis GO:0042332 26 0.073
cation transmembrane transport GO:0098655 88 0.072
protein complex biogenesis GO:0070271 201 0.071
organophosphate metabolic process GO:0019637 195 0.071
regulation of catalytic activity GO:0050790 185 0.068
purine containing compound metabolic process GO:0072521 155 0.066
apoptotic signaling pathway GO:0097190 27 0.065
molting cycle GO:0042303 56 0.064
single organism intracellular transport GO:1902582 207 0.063
multi organism behavior GO:0051705 175 0.062
nucleobase containing small molecule metabolic process GO:0055086 174 0.061
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.061
positive regulation of hydrolase activity GO:0051345 78 0.058
protein modification process GO:0036211 438 0.058
response to inorganic substance GO:0010035 44 0.056
imaginal disc derived appendage morphogenesis GO:0035114 395 0.056
intracellular transport GO:0046907 228 0.054
response to external biotic stimulus GO:0043207 293 0.054
transmembrane transport GO:0055085 139 0.054
regulation of cellular amine metabolic process GO:0033238 3 0.052
imaginal disc derived wing morphogenesis GO:0007476 337 0.051
ribonucleotide metabolic process GO:0009259 145 0.051
regulation of cell cycle GO:0051726 291 0.051
ion transmembrane transport GO:0034220 122 0.049
cellular response to dna damage stimulus GO:0006974 223 0.049
appendage morphogenesis GO:0035107 397 0.048
protein localization GO:0008104 284 0.048
regulation of cell death GO:0010941 173 0.048
positive regulation of catalytic activity GO:0043085 118 0.048
regulation of cellular catabolic process GO:0031329 157 0.047
chromatin organization GO:0006325 207 0.047
programmed cell death GO:0012501 257 0.046
intracellular signal transduction GO:0035556 300 0.046
histone modification GO:0016570 106 0.042
embryo development ending in birth or egg hatching GO:0009792 152 0.041
cell proliferation GO:0008283 299 0.041
response to light stimulus GO:0009416 124 0.041
ribose phosphate metabolic process GO:0019693 145 0.040
cell death GO:0008219 279 0.040
positive regulation of rna biosynthetic process GO:1902680 266 0.039
vesicle mediated transport GO:0016192 381 0.038
positive regulation of protein deacetylation GO:0090312 2 0.037
regulation of response to external stimulus GO:0032101 115 0.036
positive regulation of signaling GO:0023056 243 0.036
positive regulation of cell communication GO:0010647 250 0.036
regulation of hydrolase activity GO:0051336 97 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.036
organonitrogen compound biosynthetic process GO:1901566 117 0.035
open tracheal system development GO:0007424 204 0.034
positive regulation of macromolecule metabolic process GO:0010604 405 0.034
positive regulation of nucleic acid templated transcription GO:1903508 266 0.034
single organism cellular localization GO:1902580 180 0.034
growth GO:0040007 359 0.033
tube development GO:0035295 244 0.033
positive regulation of intracellular signal transduction GO:1902533 116 0.033
cation transport GO:0006812 110 0.033
regulation of erbb signaling pathway GO:1901184 42 0.032
ribonucleoside catabolic process GO:0042454 112 0.031
protein modification by small protein removal GO:0070646 28 0.030
aging GO:0007568 143 0.030
Mouse Worm
developmental growth GO:0048589 280 0.030
membrane organization GO:0061024 112 0.029
cell recognition GO:0008037 102 0.029
nucleoside triphosphate catabolic process GO:0009143 108 0.029
nucleoside phosphate metabolic process GO:0006753 162 0.029
adult chitin containing cuticle pigmentation GO:0048085 16 0.029
response to oxygen containing compound GO:1901700 200 0.028
positive regulation of gene expression GO:0010628 290 0.028
camera type eye development GO:0043010 4 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.028
nucleoside triphosphate metabolic process GO:0009141 120 0.028
enzyme linked receptor protein signaling pathway GO:0007167 179 0.028
inorganic ion transmembrane transport GO:0098660 73 0.027
adult behavior GO:0030534 137 0.027
purine nucleotide metabolic process GO:0006163 146 0.027
organic acid metabolic process GO:0006082 103 0.027
single organism biosynthetic process GO:0044711 206 0.026
nucleoside metabolic process GO:0009116 127 0.026
organelle localization GO:0051640 148 0.026
positive regulation of catabolic process GO:0009896 105 0.026
positive regulation of histone deacetylation GO:0031065 2 0.026
establishment of organelle localization GO:0051656 122 0.025
ubiquitin dependent protein catabolic process GO:0006511 78 0.025
nuclear division GO:0000280 332 0.025
organic substance catabolic process GO:1901575 308 0.025
ribonucleoside triphosphate catabolic process GO:0009203 108 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
cell cell signaling involved in cell fate commitment GO:0045168 210 0.025
regulation of catabolic process GO:0009894 170 0.025
histolysis GO:0007559 102 0.024
cellular amine metabolic process GO:0044106 12 0.024
sensory organ morphogenesis GO:0090596 260 0.024
positive regulation of cellular biosynthetic process GO:0031328 316 0.024
positive regulation of developmental process GO:0051094 143 0.024
protein deubiquitination GO:0016579 17 0.024
chemical homeostasis GO:0048878 92 0.024
death GO:0016265 284 0.023
gastrulation GO:0007369 70 0.023
response to alcohol GO:0097305 95 0.023
protein acylation GO:0043543 42 0.023
digestive tract development GO:0048565 149 0.023
adult locomotory behavior GO:0008344 76 0.023
response to organic substance GO:0010033 284 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
regulation of multi organism process GO:0043900 131 0.022
cellular protein localization GO:0034613 160 0.022
protein complex assembly GO:0006461 200 0.022
ribonucleoside triphosphate metabolic process GO:0009199 119 0.022
covalent chromatin modification GO:0016569 106 0.022
regulation of multicellular organismal development GO:2000026 414 0.021
regulation of cell morphogenesis GO:0022604 163 0.021
homeostatic process GO:0042592 199 0.021
aggressive behavior GO:0002118 63 0.021
response to decreased oxygen levels GO:0036293 58 0.021
regulation of developmental pigmentation GO:0048070 24 0.021
purine nucleoside metabolic process GO:0042278 127 0.021
organic substance transport GO:0071702 257 0.021
purine ribonucleotide metabolic process GO:0009150 145 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
salivary gland histolysis GO:0035070 88 0.020
proteolysis GO:0006508 192 0.020
regulation of cell proliferation GO:0042127 163 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.020
immune effector process GO:0002252 98 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
regulation of chitin based cuticle tanning GO:0007564 14 0.020
cellular protein catabolic process GO:0044257 83 0.019
response to hypoxia GO:0001666 53 0.019
kidney development GO:0001822 3 0.019
innate immune response GO:0045087 144 0.019
dorsal ventral pattern formation GO:0009953 133 0.019
central nervous system development GO:0007417 201 0.019
organophosphate catabolic process GO:0046434 112 0.019
purine nucleoside catabolic process GO:0006152 112 0.019
regulation of organelle organization GO:0033043 196 0.018
phagocytosis GO:0006909 215 0.018
organelle assembly GO:0070925 198 0.018
organelle fission GO:0048285 340 0.018
regulation of endocytosis GO:0030100 37 0.018
neuromuscular process GO:0050905 21 0.018
purine nucleoside monophosphate metabolic process GO:0009126 50 0.018
amine metabolic process GO:0009308 12 0.018
regulation of cell differentiation GO:0045595 302 0.018
histone mrna metabolic process GO:0008334 8 0.018
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.018
skin development GO:0043588 65 0.017
negative regulation of cell communication GO:0010648 223 0.017
spermatid differentiation GO:0048515 114 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
response to endogenous stimulus GO:0009719 119 0.017
larval development GO:0002164 104 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
regulation of response to stress GO:0080134 200 0.016
regulation of immune system process GO:0002682 176 0.016
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
inter male aggressive behavior GO:0002121 60 0.016
regulation of apoptotic process GO:0042981 130 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
nucleotide catabolic process GO:0009166 109 0.016
meiotic nuclear division GO:0007126 151 0.016
intracellular protein transport GO:0006886 104 0.016
dna metabolic process GO:0006259 227 0.016
retina development in camera type eye GO:0060041 4 0.015
cytoplasmic transport GO:0016482 130 0.015
nucleotide metabolic process GO:0009117 161 0.015
chitin based cuticle sclerotization GO:0007593 19 0.015
telencephalon development GO:0021537 2 0.015
branching morphogenesis of an epithelial tube GO:0048754 45 0.015
biological adhesion GO:0022610 138 0.015
negative regulation of defense response GO:0031348 35 0.015
regulation of synaptic transmission GO:0050804 69 0.015
atp metabolic process GO:0046034 49 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.014
nephron epithelium development GO:0072009 3 0.014
catabolic process GO:0009056 409 0.014
regulation of cytoskeleton organization GO:0051493 89 0.014
neuron projection guidance GO:0097485 241 0.014
nucleoside monophosphate metabolic process GO:0009123 52 0.014
chromatin modification GO:0016568 147 0.014
secretion GO:0046903 109 0.014
regulation of transport GO:0051049 181 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
regulation of cellular response to stress GO:0080135 89 0.013
apoptotic process GO:0006915 159 0.013
gland development GO:0048732 191 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
protein ubiquitination GO:0016567 70 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
immune response GO:0006955 246 0.013
regulation of neurotransmitter secretion GO:0046928 14 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
aromatic compound catabolic process GO:0019439 166 0.013
positive regulation of signal transduction GO:0009967 223 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
positive regulation of cell death GO:0010942 69 0.013
purine containing compound catabolic process GO:0072523 112 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
regulation of programmed cell death GO:0043067 152 0.012
post embryonic appendage morphogenesis GO:0035120 385 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
regulation of cuticle pigmentation GO:0048079 16 0.012
endocytosis GO:0006897 310 0.012
establishment of protein localization GO:0045184 163 0.012
autophagy GO:0006914 108 0.012
internal peptidyl lysine acetylation GO:0018393 38 0.012
synaptic transmission GO:0007268 288 0.012
phosphorylation GO:0016310 294 0.012
regulation of neurogenesis GO:0050767 158 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
cardiovascular system development GO:0072358 82 0.012
epithelial tube morphogenesis GO:0060562 88 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
spermatogenesis GO:0007283 200 0.012
response to biotic stimulus GO:0009607 294 0.012
negative regulation of apoptotic process GO:0043066 63 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
necrotic cell death GO:0070265 1 0.011
meiotic cell cycle GO:0051321 171 0.011
actin filament organization GO:0007015 126 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
oxoacid metabolic process GO:0043436 103 0.011
multicellular organismal aging GO:0010259 140 0.011
Worm
defense response to other organism GO:0098542 225 0.011
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.011
wing disc pattern formation GO:0035222 66 0.011
cell fate specification GO:0001708 71 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
guanosine containing compound catabolic process GO:1901069 74 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
morphogenesis of a branching epithelium GO:0061138 45 0.011
regulation of response to biotic stimulus GO:0002831 63 0.010
regulation of proteolysis GO:0030162 87 0.010
macromolecular complex assembly GO:0065003 256 0.010
regulation of vesicle mediated transport GO:0060627 59 0.010
cell adhesion GO:0007155 136 0.010
imaginal disc derived leg morphogenesis GO:0007480 80 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
positive regulation of rna metabolic process GO:0051254 271 0.010

tam disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.080
nervous system disease DOID:863 0 0.035
disease of cellular proliferation DOID:14566 0 0.029
cancer DOID:162 0 0.015
central nervous system disease DOID:331 0 0.015