Drosophila melanogaster

29 known processes

Nup58 (Dmel_CG7360)

Nucleoporin 58

(Aliases: CG7360,Dmel\CG7360,Dm NUP58)

Nup58 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of gene expression GO:0010629 387 0.163
transcription from rna polymerase ii promoter GO:0006366 368 0.143
cellular macromolecule catabolic process GO:0044265 136 0.132
positive regulation of biosynthetic process GO:0009891 316 0.127
nuclear division GO:0000280 332 0.115
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.093
regulation of organelle organization GO:0033043 196 0.090
protein localization GO:0008104 284 0.085
catabolic process GO:0009056 409 0.083
positive regulation of nucleic acid templated transcription GO:1903508 266 0.080
establishment of localization in cell GO:0051649 402 0.078
cell proliferation GO:0008283 299 0.075
organelle fission GO:0048285 340 0.071
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.068
cellular catabolic process GO:0044248 372 0.066
appendage development GO:0048736 401 0.063
regulation of gene silencing GO:0060968 63 0.063
positive regulation of cellular biosynthetic process GO:0031328 316 0.061
dna metabolic process GO:0006259 227 0.060
protein modification process GO:0036211 438 0.053
regulation of cell proliferation GO:0042127 163 0.053
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.052
imaginal disc derived appendage development GO:0048737 399 0.051
positive regulation of macromolecule metabolic process GO:0010604 405 0.050
negative regulation of cellular component organization GO:0051129 108 0.048
establishment of organelle localization GO:0051656 122 0.047
chromosome segregation GO:0007059 157 0.046
single organism cellular localization GO:1902580 180 0.045
cellular protein localization GO:0034613 160 0.044
nucleobase containing compound catabolic process GO:0034655 165 0.044
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.043
establishment or maintenance of cell polarity GO:0007163 167 0.042
organic substance catabolic process GO:1901575 308 0.040
organelle assembly GO:0070925 198 0.040
heterocycle catabolic process GO:0046700 166 0.039
regulation of cell cycle GO:0051726 291 0.038
aromatic compound catabolic process GO:0019439 166 0.038
mrna metabolic process GO:0016071 124 0.038
regulation of chromatin silencing GO:0031935 36 0.038
macromolecule catabolic process GO:0009057 161 0.037
cellular protein modification process GO:0006464 438 0.037
imaginal disc derived appendage morphogenesis GO:0035114 395 0.036
chromosome organization GO:0051276 360 0.035
meiotic cell cycle process GO:1903046 132 0.035
ubiquitin dependent protein catabolic process GO:0006511 78 0.034
wing disc morphogenesis GO:0007472 344 0.033
modification dependent macromolecule catabolic process GO:0043632 79 0.032
negative regulation of signaling GO:0023057 219 0.032
centrosome cycle GO:0007098 137 0.031
meiosis i GO:0007127 59 0.031
appendage morphogenesis GO:0035107 397 0.031
response to oxygen containing compound GO:1901700 200 0.030
embryo development ending in birth or egg hatching GO:0009792 152 0.030
positive regulation of rna metabolic process GO:0051254 271 0.030
mitotic nuclear division GO:0007067 213 0.030
response to biotic stimulus GO:0009607 294 0.029
positive regulation of rna biosynthetic process GO:1902680 266 0.029
compound eye development GO:0048749 307 0.028
intracellular signal transduction GO:0035556 300 0.028
macromolecular complex assembly GO:0065003 256 0.027
positive regulation of transcription dna templated GO:0045893 266 0.027
protein complex biogenesis GO:0070271 201 0.027
embryonic morphogenesis GO:0048598 206 0.026
enzyme linked receptor protein signaling pathway GO:0007167 179 0.026
central nervous system development GO:0007417 201 0.026
regulation of cell differentiation GO:0045595 302 0.026
positive regulation of signaling GO:0023056 243 0.025
negative regulation of cellular metabolic process GO:0031324 382 0.025
regulation of molecular function GO:0065009 217 0.025
protein catabolic process GO:0030163 101 0.025
regulation of cell cycle process GO:0010564 181 0.025
nucleoside catabolic process GO:0009164 112 0.025
mitotic spindle organization GO:0007052 220 0.024
regulation of protein localization GO:0032880 76 0.024
cellularization GO:0007349 90 0.024
meiotic cell cycle GO:0051321 171 0.024
small molecule metabolic process GO:0044281 305 0.024
regulation of cellular component biogenesis GO:0044087 201 0.023
regulation of localization GO:0032879 275 0.023
spindle organization GO:0007051 253 0.022
ribonucleoside catabolic process GO:0042454 112 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
centrosome organization GO:0051297 163 0.022
ribonucleoside metabolic process GO:0009119 127 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
dna packaging GO:0006323 91 0.022
positive regulation of cell communication GO:0010647 250 0.022
protein localization to organelle GO:0033365 82 0.021
positive regulation of response to stimulus GO:0048584 323 0.021
purine nucleoside metabolic process GO:0042278 127 0.021
regulation of catalytic activity GO:0050790 185 0.021
immune effector process GO:0002252 98 0.021
ribonucleotide catabolic process GO:0009261 109 0.021
body morphogenesis GO:0010171 2 0.020
positive regulation of gene expression GO:0010628 290 0.020
nucleoside phosphate catabolic process GO:1901292 110 0.020
regulation of catabolic process GO:0009894 170 0.020
tissue morphogenesis GO:0048729 297 0.020
single organism catabolic process GO:0044712 228 0.020
regulation of mitosis GO:0007088 56 0.020
chromatin organization GO:0006325 207 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
single organism nuclear import GO:1902593 51 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.019
chromatin remodeling GO:0006338 72 0.018
protein modification by small protein conjugation or removal GO:0070647 106 0.018
proteolysis GO:0006508 192 0.018
negative regulation of rna metabolic process GO:0051253 251 0.018
meiotic nuclear division GO:0007126 151 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
rna catabolic process GO:0006401 37 0.018
response to external biotic stimulus GO:0043207 293 0.018
segmentation GO:0035282 207 0.017
microtubule organizing center organization GO:0031023 168 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
sister chromatid segregation GO:0000819 92 0.017
eye development GO:0001654 323 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
negative regulation of signal transduction GO:0009968 206 0.017
cellular macromolecule localization GO:0070727 220 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.017
nucleotide catabolic process GO:0009166 109 0.017
male gamete generation GO:0048232 201 0.016
spermatogenesis GO:0007283 200 0.016
developmental maturation GO:0021700 172 0.016
protein transport GO:0015031 155 0.016
organonitrogen compound metabolic process GO:1901564 318 0.016
phosphorylation GO:0016310 294 0.016
nucleotide metabolic process GO:0009117 161 0.016
negative regulation of protein metabolic process GO:0051248 85 0.015
regulation of cell division GO:0051302 72 0.015
stem cell proliferation GO:0072089 88 0.015
modification dependent protein catabolic process GO:0019941 78 0.015
cellular component assembly involved in morphogenesis GO:0010927 151 0.015
regulation of immune system process GO:0002682 176 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
intracellular protein transport GO:0006886 104 0.014
protein phosphorylation GO:0006468 169 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
protein complex assembly GO:0006461 200 0.014
ribonucleoside monophosphate catabolic process GO:0009158 39 0.014
positive regulation of signal transduction GO:0009967 223 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
regulation of cellular localization GO:0060341 136 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
nucleosome organization GO:0034728 59 0.013
negative regulation of organelle organization GO:0010639 56 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
programmed cell death GO:0012501 257 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
atp metabolic process GO:0046034 49 0.013
response to other organism GO:0051707 293 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
regionalization GO:0003002 416 0.013
establishment of protein localization GO:0045184 163 0.013
microtubule anchoring GO:0034453 11 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
phagocytosis GO:0006909 215 0.013
tube morphogenesis GO:0035239 191 0.012
tube development GO:0035295 244 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
embryonic pattern specification GO:0009880 174 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
nucleoside monophosphate metabolic process GO:0009123 52 0.012
compound eye morphogenesis GO:0001745 249 0.012
mitotic cytokinesis GO:0000281 50 0.012
organophosphate catabolic process GO:0046434 112 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.012
chromosome localization GO:0050000 20 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
organophosphate metabolic process GO:0019637 195 0.012
protein targeting to nucleus GO:0044744 51 0.012
response to abiotic stimulus GO:0009628 341 0.012
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.012
establishment of protein localization to organelle GO:0072594 62 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
positive regulation of protein transport GO:0051222 37 0.012
cellular protein catabolic process GO:0044257 83 0.012
purine containing compound catabolic process GO:0072523 112 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
mrna processing GO:0006397 104 0.011
single organism intracellular transport GO:1902582 207 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
single organism membrane organization GO:0044802 93 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
regulation of transport GO:0051049 181 0.011
negative regulation of cell communication GO:0010648 223 0.011
nuclear import GO:0051170 51 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
gene silencing by rna GO:0031047 57 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
regulation of protein catabolic process GO:0042176 55 0.011
mrna catabolic process GO:0006402 33 0.010
endomembrane system organization GO:0010256 119 0.010
purine nucleotide catabolic process GO:0006195 109 0.010
cell division GO:0051301 248 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
axon development GO:0061564 297 0.010
cell death GO:0008219 279 0.010
regulation of protein modification process GO:0031399 112 0.010
peptidyl amino acid modification GO:0018193 105 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.010
multi organism behavior GO:0051705 175 0.010
regulation of protein transport GO:0051223 57 0.010
purine nucleoside catabolic process GO:0006152 112 0.010
leg disc morphogenesis GO:0007478 80 0.010
negative regulation of cellular biosynthetic process GO:0031327 277 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
chromatin modification GO:0016568 147 0.010

Nup58 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.014
sensory system disease DOID:0050155 0 0.013
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011