Drosophila melanogaster

7 known processes

Rpn3 (Dmel_CG42641)

Regulatory particle non-ATPase 3

(Aliases: DoxA2,CG10484,Dox-A2,DXA2_DROME,CG42641,l(2)37Bf,Dox,l(2)37Bf[+],p58,Dmel\CG42641,Dmel_CG10484)

Rpn3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic spindle organization GO:0007052 220 0.706
multicellular organismal aging GO:0010259 140 0.656
modification dependent macromolecule catabolic process GO:0043632 79 0.615
proteolysis GO:0006508 192 0.475
modification dependent protein catabolic process GO:0019941 78 0.472
dna repair GO:0006281 54 0.463
cellular protein catabolic process GO:0044257 83 0.413
cellular response to dna damage stimulus GO:0006974 223 0.370
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.355
regulation of endopeptidase activity GO:0052548 36 0.351
positive regulation of proteolysis GO:0045862 52 0.279
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.267
cellular catabolic process GO:0044248 372 0.244
catabolic process GO:0009056 409 0.243
ubiquitin dependent protein catabolic process GO:0006511 78 0.228
negative regulation of signaling GO:0023057 219 0.223
determination of adult lifespan GO:0008340 137 0.220
regulation of meiosis GO:0040020 3 0.179
ubiquitin homeostasis GO:0010992 1 0.174
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.173
aging GO:0007568 143 0.167
spindle organization GO:0007051 253 0.166
protein catabolic process GO:0030163 101 0.164
regulation of proteolysis GO:0030162 87 0.136
regulation of peptidase activity GO:0052547 39 0.134
response to radiation GO:0009314 155 0.132
dna metabolic process GO:0006259 227 0.132
positive regulation of endopeptidase activity GO:0010950 26 0.118
regulation of cellular component biogenesis GO:0044087 201 0.112
macromolecule catabolic process GO:0009057 161 0.112
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.102
protein modification by small protein removal GO:0070646 28 0.102
embryo development ending in birth or egg hatching GO:0009792 152 0.097
organonitrogen compound biosynthetic process GO:1901566 117 0.097
proteasomal protein catabolic process GO:0010498 59 0.093
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.092
protein deubiquitination GO:0016579 17 0.089
organelle fission GO:0048285 340 0.088
cellular protein modification process GO:0006464 438 0.088
positive regulation of peptidase activity GO:0010952 29 0.086
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.083
autophagy GO:0006914 108 0.081
organic substance transport GO:0071702 257 0.076
transcription from rna polymerase ii promoter GO:0006366 368 0.072
protein ubiquitination GO:0016567 70 0.069
regulation of catabolic process GO:0009894 170 0.067
protein complex assembly GO:0006461 200 0.066
male gamete generation GO:0048232 201 0.065
nuclear division GO:0000280 332 0.064
cellular macromolecular complex assembly GO:0034622 153 0.061
cellular macromolecule catabolic process GO:0044265 136 0.059
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.058
regulation of protein metabolic process GO:0051246 256 0.058
cell recognition GO:0008037 102 0.057
positive regulation of transcription dna templated GO:0045893 266 0.057
positive regulation of macromolecule metabolic process GO:0010604 405 0.055
spermatogenesis GO:0007283 200 0.055
double strand break repair GO:0006302 26 0.054
regulation of cell cycle process GO:0010564 181 0.053
regulation of cell cycle GO:0051726 291 0.052
gene silencing GO:0016458 138 0.051
vesicle mediated transport GO:0016192 381 0.049
protein modification process GO:0036211 438 0.049
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.048
proteasome assembly GO:0043248 2 0.046
regulation of protein catabolic process GO:0042176 55 0.045
negative regulation of gene expression GO:0010629 387 0.042
dna templated transcription elongation GO:0006354 18 0.042
macromolecular complex assembly GO:0065003 256 0.041
regulation of cellular protein metabolic process GO:0032268 243 0.041
chemotaxis GO:0006935 249 0.040
positive regulation of cellular biosynthetic process GO:0031328 316 0.040
larval development GO:0002164 104 0.039
death GO:0016265 284 0.039
response to light stimulus GO:0009416 124 0.037
regulation of proteasomal protein catabolic process GO:0061136 39 0.036
atp metabolic process GO:0046034 49 0.036
mitotic nuclear division GO:0007067 213 0.035
spindle elongation GO:0051231 83 0.034
programmed cell death GO:0012501 257 0.034
positive regulation of cellular component biogenesis GO:0044089 80 0.034
regulation of gene expression epigenetic GO:0040029 128 0.034
positive regulation of molecular function GO:0044093 136 0.033
regulation of cellular protein catabolic process GO:1903362 44 0.032
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.031
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.031
regulation of transport GO:0051049 181 0.031
positive regulation of nucleic acid templated transcription GO:1903508 266 0.030
cell death GO:0008219 279 0.030
regulation of protein complex assembly GO:0043254 42 0.028
positive regulation of cellular catabolic process GO:0031331 95 0.028
response to abiotic stimulus GO:0009628 341 0.027
small gtpase mediated signal transduction GO:0007264 88 0.027
regulation of localization GO:0032879 275 0.027
apoptotic process GO:0006915 159 0.027
response to organic substance GO:0010033 284 0.027
organonitrogen compound metabolic process GO:1901564 318 0.026
purine ribonucleoside metabolic process GO:0046128 127 0.026
regulation of cellular catabolic process GO:0031329 157 0.026
homeostatic process GO:0042592 199 0.026
immune system process GO:0002376 347 0.025
cellular protein complex assembly GO:0043623 71 0.025
regulation of developmental growth GO:0048638 174 0.024
positive regulation of hydrolase activity GO:0051345 78 0.024
cell proliferation GO:0008283 299 0.024
regulation of vesicle mediated transport GO:0060627 59 0.024
cell cycle phase transition GO:0044770 140 0.024
regulation of defense response GO:0031347 102 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
purine ribonucleotide metabolic process GO:0009150 145 0.023
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 1 0.023
hematopoietic or lymphoid organ development GO:0048534 57 0.023
protein transport GO:0015031 155 0.023
positive regulation of catalytic activity GO:0043085 118 0.022
hormone metabolic process GO:0042445 33 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.021
protein maturation GO:0051604 71 0.021
camera type eye development GO:0043010 4 0.021
protein modification by small protein conjugation or removal GO:0070647 106 0.021
regulation of organelle organization GO:0033043 196 0.021
single organism biosynthetic process GO:0044711 206 0.020
organic substance catabolic process GO:1901575 308 0.020
positive regulation of catabolic process GO:0009896 105 0.020
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.020
entry into cell of other organism involved in symbiotic interaction GO:0051806 3 0.020
positive regulation of rna metabolic process GO:0051254 271 0.019
dna recombination GO:0006310 32 0.019
protein complex biogenesis GO:0070271 201 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
positive regulation of synapse assembly GO:0051965 29 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
positive regulation of protein catabolic process GO:0045732 34 0.019
endocytosis GO:0006897 310 0.018
eggshell formation GO:0030703 105 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
response to hexose GO:0009746 3 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
gene silencing by rna GO:0031047 57 0.017
response to starvation GO:0042594 97 0.017
protein dna complex assembly GO:0065004 63 0.017
ras protein signal transduction GO:0007265 88 0.016
regulation of erk1 and erk2 cascade GO:0070372 39 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
ribose phosphate metabolic process GO:0019693 145 0.015
small molecule metabolic process GO:0044281 305 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
regulation of cell division GO:0051302 72 0.015
protein dna complex subunit organization GO:0071824 86 0.015
regulation of growth GO:0040008 233 0.014
neuron recognition GO:0008038 101 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
regulation of nuclear division GO:0051783 58 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
connective tissue development GO:0061448 3 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
regulation of hydrolase activity GO:0051336 97 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
organelle assembly GO:0070925 198 0.014
single organism catabolic process GO:0044712 228 0.014
single organism intracellular transport GO:1902582 207 0.013
establishment of protein localization GO:0045184 163 0.013
negative regulation of cell communication GO:0010648 223 0.013
phagocytosis GO:0006909 215 0.013
epithelial cell differentiation GO:0030855 322 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
positive regulation of growth GO:0045927 75 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
regulation of programmed cell death GO:0043067 152 0.013
positive regulation of developmental process GO:0051094 143 0.013
response to other organism GO:0051707 293 0.013
cullin deneddylation GO:0010388 3 0.013
lateral inhibition GO:0046331 206 0.012
intracellular signal transduction GO:0035556 300 0.012
apical junction assembly GO:0043297 32 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
regulation of synapse organization GO:0050807 110 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
double strand break repair via homologous recombination GO:0000724 13 0.012
cellular component disassembly GO:0022411 46 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.011
regulation of cellular component size GO:0032535 98 0.011
intracellular transport GO:0046907 228 0.011
developmental programmed cell death GO:0010623 138 0.011
response to nutrient levels GO:0031667 114 0.011
regulation of catalytic activity GO:0050790 185 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
cell maturation GO:0048469 144 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
anatomical structure homeostasis GO:0060249 97 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
wound healing GO:0042060 75 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
regulation of response to external stimulus GO:0032101 115 0.010
imaginal disc derived wing morphogenesis GO:0007476 337 0.010
salivary gland histolysis GO:0035070 88 0.010
ion transport GO:0006811 145 0.010
regulation of cellular response to stress GO:0080135 89 0.010
regulation of humoral immune response GO:0002920 51 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
regulation of intracellular transport GO:0032386 64 0.010
taxis GO:0042330 304 0.010
cell migration GO:0016477 238 0.010
neuron projection guidance GO:0097485 241 0.010

Rpn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.012