Drosophila melanogaster

158 known processes

Mtl (Dmel_CG5588)

Mig-2-like

(Aliases: Rac-like,Rac GTPase,Rac,dMig-2,5588,Mt1/Mig2-like,mtl,MTL,CG5588,Dmel\CG5588)

Mtl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synapse organization GO:0050808 196 0.860
Fly
imaginal disc derived wing hair organization GO:0035317 45 0.817
cell motility GO:0048870 251 0.718
establishment of tissue polarity GO:0007164 87 0.704
establishment of planar polarity GO:0001736 87 0.693
embryonic development via the syncytial blastoderm GO:0001700 148 0.646
morphogenesis of an epithelium GO:0002009 276 0.641
regulation of anatomical structure morphogenesis GO:0022603 242 0.613
positive regulation of macromolecule metabolic process GO:0010604 405 0.611
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.611
tissue morphogenesis GO:0048729 297 0.581
non sensory hair organization GO:0035316 47 0.544
regulation of cell morphogenesis GO:0022604 163 0.525
regulation of molecular function GO:0065009 217 0.510
Fly
purine ribonucleoside metabolic process GO:0046128 127 0.480
Worm Fly
hair cell differentiation GO:0035315 47 0.445
cell projection assembly GO:0030031 94 0.443
morphogenesis of a polarized epithelium GO:0001738 93 0.438
regulation of cell shape GO:0008360 113 0.429
axon midline choice point recognition GO:0016199 26 0.428
Fly
axon choice point recognition GO:0016198 26 0.418
Fly
guanosine containing compound metabolic process GO:1901068 74 0.413
Worm Fly
tube morphogenesis GO:0035239 191 0.383
Worm Fly
embryonic morphogenesis GO:0048598 206 0.361
regulation of multicellular organismal development GO:2000026 414 0.354
actin polymerization or depolymerization GO:0008154 31 0.353
Fly
positive regulation of phosphate metabolic process GO:0045937 139 0.349
Fly
regulation of nervous system development GO:0051960 248 0.344
Fly
brain development GO:0007420 120 0.343
cellular protein complex assembly GO:0043623 71 0.337
Fly
gliogenesis GO:0042063 80 0.334
Fly
regulation of cytoskeleton organization GO:0051493 89 0.330
Fly
regulation of programmed cell death GO:0043067 152 0.320
organonitrogen compound metabolic process GO:1901564 318 0.316
Worm Fly
compound eye morphogenesis GO:0001745 249 0.310
protein complex biogenesis GO:0070271 201 0.304
Fly
protein modification process GO:0036211 438 0.299
Worm Fly
imaginal disc derived appendage development GO:0048737 399 0.286
epithelial cell differentiation GO:0030855 322 0.284
regulation of lamellipodium organization GO:1902743 15 0.281
Fly
localization of cell GO:0051674 257 0.281
glial cell migration GO:0008347 31 0.276
Fly
regulation of phosphate metabolic process GO:0019220 210 0.270
Worm Fly
guanosine containing compound catabolic process GO:1901069 74 0.260
Worm Fly
gland development GO:0048732 191 0.255
actin filament based process GO:0030029 220 0.254
regulation of organ morphogenesis GO:2000027 78 0.252
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.242
nucleotide catabolic process GO:0009166 109 0.239
Worm Fly
regulation of actin cytoskeleton organization GO:0032956 42 0.239
Fly
neuromuscular junction development GO:0007528 149 0.237
Fly
protein polymerization GO:0051258 42 0.235
Fly
synapse assembly GO:0007416 143 0.231
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.229
Worm Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.228
Fly
neuron projection guidance GO:0097485 241 0.225
Worm Fly
regulation of intracellular signal transduction GO:1902531 236 0.221
actin filament bundle organization GO:0061572 28 0.220
aromatic compound catabolic process GO:0019439 166 0.220
Worm Fly
positive regulation of cellular component organization GO:0051130 156 0.217
Fly
cytokinetic cell separation GO:0000920 1 0.208
regulation of cysteine type endopeptidase activity GO:2000116 27 0.201
negative regulation of multicellular organismal process GO:0051241 142 0.200
positive regulation of catabolic process GO:0009896 105 0.199
regulation of phosphorylation GO:0042325 147 0.193
Worm Fly
negative regulation of cell development GO:0010721 62 0.192
nucleobase containing small molecule metabolic process GO:0055086 174 0.189
Worm Fly
head development GO:0060322 135 0.188
nucleobase containing compound catabolic process GO:0034655 165 0.184
Worm Fly
regulation of actin filament polymerization GO:0030833 25 0.183
Fly
rho protein signal transduction GO:0007266 14 0.182
Fly
mushroom body development GO:0016319 70 0.182
synaptic growth at neuromuscular junction GO:0051124 119 0.179
Fly
regulation of cell differentiation GO:0045595 302 0.178
Fly
central nervous system development GO:0007417 201 0.178
Fly
growth GO:0040007 359 0.178
g protein coupled receptor signaling pathway GO:0007186 136 0.176
purine ribonucleoside catabolic process GO:0046130 112 0.174
Worm Fly
nucleoside metabolic process GO:0009116 127 0.170
Worm Fly
regulation of actin polymerization or depolymerization GO:0008064 27 0.169
Fly
regulation of catalytic activity GO:0050790 185 0.168
Fly
proteolysis GO:0006508 192 0.168
carbohydrate derivative metabolic process GO:1901135 217 0.167
Worm Fly
immune effector process GO:0002252 98 0.166
Fly
muscle attachment GO:0016203 36 0.165
Fly
regulation of gtpase activity GO:0043087 44 0.165
regulation of neurogenesis GO:0050767 158 0.164
Fly
macromolecular complex assembly GO:0065003 256 0.164
Fly
actin filament polymerization GO:0030041 27 0.164
Fly
positive regulation of cell motility GO:2000147 3 0.163
morphogenesis of embryonic epithelium GO:0016331 94 0.161
regulation of protein metabolic process GO:0051246 256 0.160
Worm Fly
forebrain development GO:0030900 2 0.159
appendage morphogenesis GO:0035107 397 0.159
imaginal disc derived wing morphogenesis GO:0007476 337 0.158
intracellular signal transduction GO:0035556 300 0.158
axon development GO:0061564 297 0.157
Worm Fly
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.156
cellular catabolic process GO:0044248 372 0.156
Worm Fly
regulation of establishment of planar polarity GO:0090175 22 0.154
positive regulation of nucleotide metabolic process GO:0045981 55 0.154
cell proliferation GO:0008283 299 0.153
Fly
ribonucleotide metabolic process GO:0009259 145 0.149
Worm Fly
cell death GO:0008219 279 0.148
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.147
Worm Fly
programmed cell death GO:0012501 257 0.147
regulation of nucleotide catabolic process GO:0030811 48 0.146
positive regulation of nucleotide catabolic process GO:0030813 46 0.142
wing disc morphogenesis GO:0007472 344 0.140
positive regulation of cellular catabolic process GO:0031331 95 0.139
actin nucleation GO:0045010 8 0.138
regulation of cell death GO:0010941 173 0.138
dorsal closure GO:0007391 79 0.137
axonogenesis GO:0007409 290 0.136
Worm Fly
purine nucleoside catabolic process GO:0006152 112 0.134
Worm Fly
positive regulation of organelle organization GO:0010638 65 0.133
purine ribonucleotide metabolic process GO:0009150 145 0.132
Worm Fly
gtp catabolic process GO:0006184 72 0.131
Worm Fly
regulation of embryonic cell shape GO:0016476 30 0.130
positive regulation of cellular component biogenesis GO:0044089 80 0.130
Fly
regulation of protein polymerization GO:0032271 28 0.130
Fly
chemotaxis GO:0006935 249 0.129
Worm Fly
regulation of cell projection organization GO:0031344 92 0.128
Fly
cellular protein modification process GO:0006464 438 0.128
Worm Fly
response to carbon dioxide GO:0010037 4 0.127
positive regulation of protein complex assembly GO:0031334 22 0.124
neurological system process GO:0050877 358 0.124
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.122
Fly
cellular response to carbon dioxide GO:0071244 2 0.122
cellularization GO:0007349 90 0.121
positive regulation of phosphorus metabolic process GO:0010562 139 0.121
Fly
regulation of cellular component biogenesis GO:0044087 201 0.120
Fly
gastrulation GO:0007369 70 0.117
Worm Fly
regulation of organelle organization GO:0033043 196 0.116
Fly
regulation of synapse organization GO:0050807 110 0.116
Fly
response to organic substance GO:0010033 284 0.115
positive regulation of gtpase activity GO:0043547 43 0.115
establishment or maintenance of cell polarity GO:0007163 167 0.109
nucleoside catabolic process GO:0009164 112 0.108
Worm Fly
regulation of neuron differentiation GO:0045664 103 0.107
Fly
positive regulation of rho gtpase activity GO:0032321 19 0.106
positive regulation of hydrolase activity GO:0051345 78 0.106
positive regulation of catalytic activity GO:0043085 118 0.105
Fly
cortical actin cytoskeleton organization GO:0030866 24 0.103
Fly
purine containing compound catabolic process GO:0072523 112 0.103
Worm Fly
organic substance catabolic process GO:1901575 308 0.102
Worm Fly
regulation of proteolysis GO:0030162 87 0.102
cellular nitrogen compound catabolic process GO:0044270 165 0.101
Worm Fly
positive regulation of transcription dna templated GO:0045893 266 0.101
ameboidal type cell migration GO:0001667 151 0.100
Worm Fly
peptide metabolic process GO:0006518 80 0.100
regulation of ras protein signal transduction GO:0046578 93 0.099
purine nucleoside metabolic process GO:0042278 127 0.098
Worm Fly
epithelial cell development GO:0002064 274 0.097
Fly
regulation of actin filament length GO:0030832 27 0.097
Fly
metarhodopsin inactivation GO:0016060 5 0.096
epidermis development GO:0008544 65 0.096
non canonical wnt signaling pathway GO:0035567 8 0.094
collateral sprouting GO:0048668 3 0.093
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.092
establishment of localization in cell GO:0051649 402 0.091
ribose phosphate metabolic process GO:0019693 145 0.090
Worm Fly
protein modification by small protein conjugation or removal GO:0070647 106 0.088
apoptotic process GO:0006915 159 0.087
death GO:0016265 284 0.086
regulation of cell proliferation GO:0042127 163 0.085
positive regulation of cytoskeleton organization GO:0051495 21 0.085
regulation of cellular protein metabolic process GO:0032268 243 0.085
Worm Fly
negative regulation of cellular component organization GO:0051129 108 0.084
Fly
spindle organization GO:0007051 253 0.083
glycosyl compound catabolic process GO:1901658 112 0.082
Worm Fly
metal ion homeostasis GO:0055065 44 0.081
regulation of cell cell adhesion GO:0022407 21 0.081
regulation of localization GO:0032879 275 0.081
Fly
cellular macromolecular complex assembly GO:0034622 153 0.080
Fly
cell fate determination GO:0001709 91 0.079
regulation of nucleoside metabolic process GO:0009118 50 0.079
regulation of protein complex assembly GO:0043254 42 0.078
Fly
positive regulation of nucleoside metabolic process GO:0045979 47 0.078
protein modification by small protein conjugation GO:0032446 79 0.077
regulation of hydrolase activity GO:0051336 97 0.077
actin filament bundle assembly GO:0051017 26 0.077
convergent extension GO:0060026 2 0.077
ribonucleoside catabolic process GO:0042454 112 0.076
Worm Fly
nucleoside phosphate catabolic process GO:1901292 110 0.076
Worm Fly
epidermal cell differentiation GO:0009913 51 0.076
immune system process GO:0002376 347 0.075
actin cytoskeleton organization GO:0030036 206 0.075
actomyosin structure organization GO:0031032 56 0.075
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.073
positive regulation of molecular function GO:0044093 136 0.072
Fly
actin filament organization GO:0007015 126 0.071
digestive tract morphogenesis GO:0048546 127 0.071
Worm Fly
regulation of apoptotic process GO:0042981 130 0.070
regulation of actin filament based process GO:0032970 42 0.070
Fly
developmental growth involved in morphogenesis GO:0060560 65 0.069
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.069
post embryonic appendage morphogenesis GO:0035120 385 0.068
protein maturation GO:0051604 71 0.068
catabolic process GO:0009056 409 0.067
Worm Fly
regulation of cell development GO:0060284 215 0.067
Fly
regulation of anatomical structure size GO:0090066 163 0.067
Fly
wnt signaling pathway GO:0016055 98 0.067
mapk cascade GO:0000165 107 0.066
chaeta development GO:0022416 97 0.066
negative regulation of programmed cell death GO:0043069 72 0.066
digestive tract development GO:0048565 149 0.064
Worm Fly
homeostatic process GO:0042592 199 0.064
single organism behavior GO:0044708 391 0.064
regulation of rho protein signal transduction GO:0035023 20 0.064
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.063
Fly
negative regulation of neurogenesis GO:0050768 53 0.062
compound eye development GO:0048749 307 0.062
purine ribonucleotide catabolic process GO:0009154 109 0.062
Worm Fly
nucleoside triphosphate metabolic process GO:0009141 120 0.061
Worm Fly
regulation of ras gtpase activity GO:0032318 38 0.061
ovarian follicle cell migration GO:0007297 121 0.060
Fly
single organism intracellular transport GO:1902582 207 0.060
purine nucleotide metabolic process GO:0006163 146 0.060
Worm Fly
positive regulation of ras gtpase activity GO:0032320 36 0.060
phagocytosis GO:0006909 215 0.059
Worm Fly
protein complex assembly GO:0006461 200 0.059
Fly
convergent extension involved in gastrulation GO:0060027 2 0.059
regulation of cellular component size GO:0032535 98 0.059
Fly
positive regulation of cell migration GO:0030335 2 0.058
purine containing compound metabolic process GO:0072521 155 0.057
Worm Fly
asymmetric protein localization GO:0008105 33 0.056
embryo development ending in birth or egg hatching GO:0009792 152 0.056
muscle structure development GO:0061061 224 0.056
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.056
activation of cysteine type endopeptidase activity GO:0097202 17 0.056
pigment metabolic process GO:0042440 84 0.056
Fly
positive regulation of intracellular signal transduction GO:1902533 116 0.055
nucleotide metabolic process GO:0009117 161 0.055
Worm Fly
stem cell proliferation GO:0072089 88 0.055
Fly
regulation of mapk cascade GO:0043408 92 0.054
regulation of cellular amino acid metabolic process GO:0006521 0 0.054
negative regulation of nervous system development GO:0051961 92 0.054
body morphogenesis GO:0010171 2 0.054
organophosphate metabolic process GO:0019637 195 0.053
Worm Fly
negative regulation of developmental process GO:0051093 201 0.053
appendage development GO:0048736 401 0.053
negative regulation of growth GO:0045926 84 0.052
melanin metabolic process GO:0006582 47 0.051
Fly
establishment of proximal distal cell polarity GO:0022606 4 0.051
Fly
positive regulation of calcium ion transport GO:0051928 4 0.051
positive regulation of cell cycle GO:0045787 43 0.050
positive regulation of programmed cell death GO:0043068 62 0.049
positive regulation of signal transduction GO:0009967 223 0.049
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.049
organonitrogen compound catabolic process GO:1901565 128 0.048
Worm Fly
purine nucleoside triphosphate metabolic process GO:0009144 119 0.048
Worm Fly
phosphorylation GO:0016310 294 0.048
cell type specific apoptotic process GO:0097285 38 0.048
regulation of purine nucleotide catabolic process GO:0033121 48 0.047
protein ubiquitination GO:0016567 70 0.047
determination of adult lifespan GO:0008340 137 0.047
regulation of embryonic development GO:0045995 68 0.047
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.047
endosomal transport GO:0016197 44 0.047
response to oxygen containing compound GO:1901700 200 0.046
positive regulation of transferase activity GO:0051347 26 0.046
Fly
negative regulation of cell death GO:0060548 81 0.046
regulation of peptidase activity GO:0052547 39 0.046
single organism catabolic process GO:0044712 228 0.045
Worm Fly
negative regulation of cell differentiation GO:0045596 143 0.045
cellular protein localization GO:0034613 160 0.045
regulation of axonogenesis GO:0050770 32 0.045
Fly
sensory perception GO:0007600 196 0.045
Fly
male gamete generation GO:0048232 201 0.044
Fly
apical constriction involved in gastrulation GO:0003384 7 0.044
neuroblast division GO:0055057 35 0.044
Fly
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.044
sensory organ morphogenesis GO:0090596 260 0.044
positive regulation of actin filament polymerization GO:0030838 11 0.044
regulation of notch signaling pathway GO:0008593 100 0.044
regulation of catabolic process GO:0009894 170 0.043
ribonucleotide catabolic process GO:0009261 109 0.043
Worm Fly
small molecule metabolic process GO:0044281 305 0.043
Worm Fly
neuroblast proliferation GO:0007405 74 0.043
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.042
glycosyl compound metabolic process GO:1901657 127 0.042
Worm Fly
peptidyl threonine phosphorylation GO:0018107 2 0.042
ribonucleoside metabolic process GO:0009119 127 0.042
Worm Fly
vesicle mediated transport GO:0016192 381 0.042
Worm Fly
asymmetric cell division GO:0008356 37 0.042
initiation of dorsal closure GO:0007392 12 0.042
regulation of synapse assembly GO:0051963 94 0.041
Fly
membrane organization GO:0061024 112 0.041
Worm
establishment of ommatidial planar polarity GO:0042067 49 0.041
nucleoside phosphate metabolic process GO:0006753 162 0.041
Worm Fly
gtp metabolic process GO:0046039 72 0.041
Worm Fly
cellular homeostasis GO:0019725 80 0.040
cell migration GO:0016477 238 0.040
regulation of transferase activity GO:0051338 58 0.040
Fly
actin filament based movement GO:0030048 26 0.039
organophosphate catabolic process GO:0046434 112 0.039
Worm Fly
organelle assembly GO:0070925 198 0.039
macromolecule catabolic process GO:0009057 161 0.039
cell growth GO:0016049 108 0.039
positive regulation of gtp catabolic process GO:0033126 43 0.039
positive regulation of response to stimulus GO:0048584 323 0.039
heterocycle catabolic process GO:0046700 166 0.039
Worm Fly
cellular lipid metabolic process GO:0044255 83 0.038
regulation of actin nucleation GO:0051125 3 0.038
oocyte maturation GO:0001556 3 0.038
neuron recognition GO:0008038 101 0.038
Fly
regulation of endopeptidase activity GO:0052548 36 0.037
positive regulation of protein kinase activity GO:0045860 25 0.037
Fly
axis elongation GO:0003401 3 0.037
fusome organization GO:0045478 13 0.037
intercellular bridge organization GO:0043063 14 0.037
regulation of gtp catabolic process GO:0033124 44 0.036
cell adhesion GO:0007155 136 0.036
ribonucleoside triphosphate metabolic process GO:0009199 119 0.036
Worm Fly
carboxylic acid metabolic process GO:0019752 92 0.035
positive regulation of cytosolic calcium ion concentration GO:0007204 10 0.035
response to organonitrogen compound GO:0010243 75 0.034
establishment of monopolar cell polarity GO:0061162 15 0.034
Fly
protein processing GO:0016485 68 0.034
chromosome organization GO:0051276 360 0.033
regulation of cellular component movement GO:0051270 42 0.033
tube development GO:0035295 244 0.033
Worm Fly
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.032
regulation of nucleotide metabolic process GO:0006140 62 0.032
dorsal closure spreading of leading edge cells GO:0007395 4 0.031
camera type eye development GO:0043010 4 0.031
negative regulation of synapse assembly GO:0051964 39 0.031
cytoplasmic transport GO:0016482 130 0.031
regulation of locomotion GO:0040012 42 0.031
axon extension GO:0048675 32 0.031
Worm Fly
regulation of cell adhesion GO:0030155 27 0.031
establishment of cell polarity GO:0030010 40 0.031
Fly
negative regulation of apoptotic process GO:0043066 63 0.031
axon extension involved in axon guidance GO:0048846 10 0.031
Worm
regulation of rho gtpase activity GO:0032319 20 0.031
epithelial cell morphogenesis GO:0003382 25 0.030
chemical homeostasis GO:0048878 92 0.030
positive regulation of phosphorylation GO:0042327 87 0.030
Fly
negative regulation of developmental growth GO:0048640 64 0.030
small gtpase mediated signal transduction GO:0007264 88 0.029
Fly
telencephalon development GO:0021537 2 0.029
actin cytoskeleton reorganization GO:0031532 22 0.029
proteasomal protein catabolic process GO:0010498 59 0.029
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.028
organic cyclic compound catabolic process GO:1901361 168 0.028
Worm Fly
digestive system development GO:0055123 149 0.028
Worm Fly
protein catabolic process GO:0030163 101 0.028
cellular component assembly involved in morphogenesis GO:0010927 151 0.028
Fly
maintenance of location GO:0051235 73 0.028
Fly
positive regulation of jun kinase activity GO:0043507 4 0.028
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.027
extrinsic apoptotic signaling pathway GO:0097191 1 0.027
melanotic encapsulation of foreign target GO:0035011 30 0.027
Fly
positive regulation of mapk cascade GO:0043410 63 0.027
mitotic spindle organization GO:0007052 220 0.027
positive regulation of cellular protein metabolic process GO:0032270 118 0.027
Fly
negative regulation of phosphorus metabolic process GO:0010563 45 0.027
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.027
Fly
carbohydrate derivative catabolic process GO:1901136 118 0.027
Worm Fly
purine nucleotide catabolic process GO:0006195 109 0.027
Worm Fly
lipid metabolic process GO:0006629 121 0.026
positive regulation of lipid metabolic process GO:0045834 4 0.026
eye morphogenesis GO:0048592 260 0.026
negative regulation of cellular metabolic process GO:0031324 382 0.026
jnk cascade GO:0007254 50 0.026
positive regulation of rna biosynthetic process GO:1902680 266 0.025
protein localization GO:0008104 284 0.025
Fly
positive regulation of cell death GO:0010942 69 0.025
multicellular organismal aging GO:0010259 140 0.025
response to other organism GO:0051707 293 0.024
Fly
signal transduction by phosphorylation GO:0023014 107 0.024
cation homeostasis GO:0055080 51 0.024
cilium organization GO:0044782 41 0.024
dendrite development GO:0016358 204 0.024
Fly
cell division GO:0051301 248 0.024
Fly
regulation of cellular catabolic process GO:0031329 157 0.024
response to axon injury GO:0048678 12 0.024
cellular amide metabolic process GO:0043603 80 0.023
imaginal disc fusion GO:0046528 19 0.023
hematopoietic or lymphoid organ development GO:0048534 57 0.023
muscle cell differentiation GO:0042692 103 0.023
Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.023
regulation of purine nucleotide metabolic process GO:1900542 62 0.022
humoral immune response GO:0006959 117 0.022
dorsal ventral axon guidance GO:0033563 2 0.022
Worm
regulation of proteasomal protein catabolic process GO:0061136 39 0.022
endocytosis GO:0006897 310 0.022
Worm Fly
female germline ring canal formation GO:0007301 9 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.021
Worm Fly
cell recognition GO:0008037 102 0.021
Fly
calcium ion transport into cytosol GO:0060402 2 0.021
ras protein signal transduction GO:0007265 88 0.021
Fly
skin development GO:0043588 65 0.021
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.021
reproductive system development GO:0061458 74 0.021
olfactory learning GO:0008355 56 0.020
positive regulation of proteolysis GO:0045862 52 0.020
regulation of microtubule based process GO:0032886 49 0.020
developmental growth GO:0048589 280 0.020
response to lipopolysaccharide GO:0032496 4 0.020
negative regulation of protein metabolic process GO:0051248 85 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.020
cell migration involved in gastrulation GO:0042074 9 0.020
Worm Fly
positive regulation of apoptotic process GO:0043065 47 0.020
positive regulation of cell projection organization GO:0031346 29 0.020
Fly
regulation of response to external stimulus GO:0032101 115 0.020
striated muscle myosin thick filament assembly GO:0071688 3 0.020
endoderm formation GO:0001706 3 0.019
glial cell differentiation GO:0010001 35 0.019
reproductive behavior GO:0019098 122 0.019
Fly
cytosolic calcium ion transport GO:0060401 2 0.019
regulation of lamellipodium assembly GO:0010591 15 0.019
Fly
regulation of axon regeneration GO:0048679 4 0.019
positive regulation of protein metabolic process GO:0051247 128 0.019
Fly
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
regulation of behavior GO:0050795 75 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
hemocyte migration GO:0035099 19 0.019
response to external biotic stimulus GO:0043207 293 0.018
Fly
regulation of cellular amine metabolic process GO:0033238 3 0.018
germline ring canal formation GO:0030725 13 0.018
embryonic pattern specification GO:0009880 174 0.018
Fly
regulation of cell cycle process GO:0010564 181 0.018
positive regulation of nervous system development GO:0051962 69 0.018
blastoderm segmentation GO:0007350 159 0.018
Fly
positive regulation of protein polymerization GO:0032273 14 0.018
regulation of protein phosphorylation GO:0001932 64 0.018
Worm Fly
cellular macromolecule localization GO:0070727 220 0.018
Fly
negative regulation of homeostatic process GO:0032845 2 0.018
lamellipodium organization GO:0097581 21 0.017
regulation of response to stress GO:0080134 200 0.017
gastrulation with mouth forming first GO:0001703 36 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
regulation of protein serine threonine kinase activity GO:0071900 25 0.017
Fly
organic substance transport GO:0071702 257 0.017
negative regulation of molecular function GO:0044092 51 0.017
positive regulation of rac gtpase activity GO:0032855 8 0.017
response to radiation GO:0009314 155 0.017
eye development GO:0001654 323 0.017
male gonad development GO:0008584 9 0.017
biological adhesion GO:0022610 138 0.017
positive regulation of stress fiber assembly GO:0051496 3 0.017
positive regulation of response to wounding GO:1903036 15 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
negative regulation of retinal cell programmed cell death GO:0046671 7 0.017
parallel actin filament bundle assembly GO:0030046 2 0.017
ubiquitin dependent protein catabolic process GO:0006511 78 0.017
regulation of production of molecular mediator of immune response GO:0002700 44 0.017
golgi vesicle transport GO:0048193 27 0.017
regulation of small gtpase mediated signal transduction GO:0051056 93 0.016
positive regulation of kinase activity GO:0033674 25 0.016
Fly
sensory perception of mechanical stimulus GO:0050954 72 0.016
Fly
defense response to other organism GO:0098542 225 0.016
Fly
modification dependent protein catabolic process GO:0019941 78 0.016
cilium assembly GO:0042384 38 0.016
response to nutrient levels GO:0031667 114 0.016
positive regulation of endopeptidase activity GO:0010950 26 0.016
pericardial nephrocyte differentiation GO:0061320 9 0.016
oxoacid metabolic process GO:0043436 103 0.016
limb morphogenesis GO:0035108 1 0.016
positive regulation of mitotic cell cycle GO:0045931 34 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
Worm
positive regulation of cell differentiation GO:0045597 64 0.016
establishment of spindle orientation GO:0051294 18 0.016
developmental induction GO:0031128 3 0.016
cellular response to chemical stimulus GO:0070887 199 0.015
chromosome segregation GO:0007059 157 0.015
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.015
organelle localization GO:0051640 148 0.015
formation of primary germ layer GO:0001704 24 0.015
Worm Fly
single organism cell adhesion GO:0098602 47 0.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.015
Worm Fly
organic acid metabolic process GO:0006082 103 0.015
positive regulation of cell proliferation GO:0008284 47 0.015
negative regulation of signaling GO:0023057 219 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.015
skeletal muscle fiber development GO:0048741 3 0.015
anterior posterior pattern specification GO:0009952 136 0.015
Fly
microtubule based movement GO:0007018 51 0.015
ovarian follicle cell development GO:0030707 248 0.015
Fly
epithelial cell migration GO:0010631 148 0.014
Fly
chaeta morphogenesis GO:0008407 42 0.014
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.014
response to abiotic stimulus GO:0009628 341 0.014
photoreceptor cell development GO:0042461 96 0.014
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.014
sensory perception of pain GO:0019233 4 0.014
apical constriction GO:0003383 18 0.014
regulation of protein modification process GO:0031399 112 0.014
Worm Fly
regulation of cytokinesis GO:0032465 3 0.014
nuclear transcribed mrna poly a tail shortening GO:0000289 12 0.014

Mtl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.073
nervous system disease DOID:863 0 0.056
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
eye disease DOID:5614 0 0.020