Drosophila melanogaster

55 known processes

cln3 (Dmel_CG5582)

CG5582 gene product from transcript CG5582-RA

(Aliases: CLN3,CG5582,Dmel\CG5582)

cln3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of adult lifespan GO:0008340 137 0.370
apoptotic process GO:0006915 159 0.300
intracellular signal transduction GO:0035556 300 0.295
positive regulation of macromolecule metabolic process GO:0010604 405 0.288
ameboidal type cell migration GO:0001667 151 0.279
multicellular organismal aging GO:0010259 140 0.271
small molecule metabolic process GO:0044281 305 0.268
regulation of intracellular signal transduction GO:1902531 236 0.249
epithelial cell development GO:0002064 274 0.233
homeostatic process GO:0042592 199 0.226
single organism biosynthetic process GO:0044711 206 0.220
regulation of programmed cell death GO:0043067 152 0.203
programmed cell death GO:0012501 257 0.202
response to oxidative stress GO:0006979 86 0.196
aging GO:0007568 143 0.188
death GO:0016265 284 0.186
epithelial cell differentiation GO:0030855 322 0.186
lipid metabolic process GO:0006629 121 0.182
response to organic substance GO:0010033 284 0.179
organonitrogen compound metabolic process GO:1901564 318 0.179
regulation of apoptotic process GO:0042981 130 0.175
catabolic process GO:0009056 409 0.169
compound eye morphogenesis GO:0001745 249 0.168
endocytosis GO:0006897 310 0.156
tissue morphogenesis GO:0048729 297 0.153
regulation of cell death GO:0010941 173 0.149
growth GO:0040007 359 0.149
eye development GO:0001654 323 0.147
cell death GO:0008219 279 0.144
cellular protein modification process GO:0006464 438 0.143
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.142
localization of cell GO:0051674 257 0.141
tube development GO:0035295 244 0.141
positive regulation of response to stimulus GO:0048584 323 0.137
embryonic development via the syncytial blastoderm GO:0001700 148 0.136
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.134
response to oxygen containing compound GO:1901700 200 0.134
response to radiation GO:0009314 155 0.130
negative regulation of cell communication GO:0010648 223 0.129
establishment of localization in cell GO:0051649 402 0.127
cellular catabolic process GO:0044248 372 0.126
organophosphate metabolic process GO:0019637 195 0.124
negative regulation of cellular metabolic process GO:0031324 382 0.122
sensory organ morphogenesis GO:0090596 260 0.118
columnar cuboidal epithelial cell development GO:0002066 249 0.117
regulation of anatomical structure morphogenesis GO:0022603 242 0.116
negative regulation of signal transduction GO:0009968 206 0.115
organic hydroxy compound metabolic process GO:1901615 83 0.114
regulation of cellular catabolic process GO:0031329 157 0.113
cell migration GO:0016477 238 0.112
regulation of cell differentiation GO:0045595 302 0.112
regulation of protein metabolic process GO:0051246 256 0.110
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.110
regulation of catabolic process GO:0009894 170 0.110
regulation of cellular protein metabolic process GO:0032268 243 0.110
cellular amino acid metabolic process GO:0006520 61 0.110
chemotaxis GO:0006935 249 0.109
defense response GO:0006952 300 0.109
epithelium migration GO:0090132 148 0.105
organic substance catabolic process GO:1901575 308 0.102
phosphorylation GO:0016310 294 0.100
tissue migration GO:0090130 155 0.100
positive regulation of rna metabolic process GO:0051254 271 0.098
positive regulation of cellular protein metabolic process GO:0032270 118 0.096
protein modification process GO:0036211 438 0.096
oxoacid metabolic process GO:0043436 103 0.095
vesicle mediated transport GO:0016192 381 0.094
taxis GO:0042330 304 0.093
protein phosphorylation GO:0006468 169 0.092
response to alcohol GO:0097305 95 0.090
positive regulation of signal transduction GO:0009967 223 0.088
epithelial cell migration GO:0010631 148 0.086
negative regulation of response to stimulus GO:0048585 258 0.086
positive regulation of molecular function GO:0044093 136 0.085
response to abiotic stimulus GO:0009628 341 0.084
posttranscriptional regulation of gene expression GO:0010608 145 0.083
regulation of transport GO:0051049 181 0.082
developmental growth GO:0048589 280 0.081
cellular response to chemical stimulus GO:0070887 199 0.079
positive regulation of catalytic activity GO:0043085 118 0.079
signal transduction by phosphorylation GO:0023014 107 0.079
positive regulation of peptidase activity GO:0010952 29 0.078
response to oxygen radical GO:0000305 3 0.078
negative regulation of signaling GO:0023057 219 0.078
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.077
positive regulation of signaling GO:0023056 243 0.077
regulation of localization GO:0032879 275 0.077
positive regulation of catabolic process GO:0009896 105 0.077
morphogenesis of embryonic epithelium GO:0016331 94 0.077
regulation of phosphate metabolic process GO:0019220 210 0.076
oxidation reduction process GO:0055114 123 0.076
eye morphogenesis GO:0048592 260 0.076
cellular response to oxygen containing compound GO:1901701 79 0.075
carboxylic acid metabolic process GO:0019752 92 0.075
neurological system process GO:0050877 358 0.073
dorsal closure GO:0007391 79 0.071
positive regulation of phosphate metabolic process GO:0045937 139 0.071
organic acid metabolic process GO:0006082 103 0.071
regulation of multicellular organismal development GO:2000026 414 0.070
cellular ketone metabolic process GO:0042180 24 0.069
single organism catabolic process GO:0044712 228 0.069
organic substance transport GO:0071702 257 0.068
regulation of phosphorylation GO:0042325 147 0.067
appendage development GO:0048736 401 0.067
connective tissue development GO:0061448 3 0.067
response to lipopolysaccharide GO:0032496 4 0.065
axonogenesis GO:0007409 290 0.063
axon guidance GO:0007411 233 0.063
purine containing compound metabolic process GO:0072521 155 0.063
kidney development GO:0001822 3 0.062
immune response regulating signaling pathway GO:0002764 2 0.062
regulation of molecular function GO:0065009 217 0.061
positive regulation of protein metabolic process GO:0051247 128 0.061
wnt signaling pathway GO:0016055 98 0.060
immune response activating signal transduction GO:0002757 2 0.060
negative regulation of multicellular organismal process GO:0051241 142 0.059
morphogenesis of an epithelium GO:0002009 276 0.059
proteolysis GO:0006508 192 0.059
response to nitrogen compound GO:1901698 90 0.058
cell division GO:0051301 248 0.058
locomotory behavior GO:0007626 176 0.057
heterocycle catabolic process GO:0046700 166 0.057
positive regulation of cellular biosynthetic process GO:0031328 316 0.057
transcription from rna polymerase ii promoter GO:0006366 368 0.056
carbohydrate derivative metabolic process GO:1901135 217 0.056
single organism intracellular transport GO:1902582 207 0.056
positive regulation of phosphorus metabolic process GO:0010562 139 0.056
regulation of cellular ketone metabolic process GO:0010565 3 0.056
negative regulation of developmental process GO:0051093 201 0.055
ovarian follicle cell development GO:0030707 248 0.054
regulation of cellular localization GO:0060341 136 0.053
response to bacterium GO:0009617 198 0.053
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.053
ribonucleotide metabolic process GO:0009259 145 0.053
negative regulation of cell differentiation GO:0045596 143 0.053
nucleobase containing small molecule metabolic process GO:0055086 174 0.053
intracellular transport GO:0046907 228 0.051
compound eye development GO:0048749 307 0.050
regulation of cellular amine metabolic process GO:0033238 3 0.050
regulation of catalytic activity GO:0050790 185 0.050
multicellular organism growth GO:0035264 46 0.050
response to nutrient levels GO:0031667 114 0.049
positive regulation of biosynthetic process GO:0009891 316 0.049
apoptotic signaling pathway GO:0097190 27 0.049
response to other organism GO:0051707 293 0.049
positive regulation of proteolysis GO:0045862 52 0.049
response to organic cyclic compound GO:0014070 89 0.049
regulation of cellular response to stress GO:0080135 89 0.049
actin cytoskeleton organization GO:0030036 206 0.048
cellular response to abiotic stimulus GO:0071214 58 0.048
phagocytosis GO:0006909 215 0.048
cell type specific apoptotic process GO:0097285 38 0.048
regulation of cellular amino acid metabolic process GO:0006521 0 0.048
purine ribonucleoside metabolic process GO:0046128 127 0.047
nuclear division GO:0000280 332 0.047
embryonic morphogenesis GO:0048598 206 0.047
purine ribonucleotide metabolic process GO:0009150 145 0.047
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.047
intrinsic apoptotic signaling pathway GO:0097193 16 0.047
regulation of growth GO:0040008 233 0.046
g protein coupled receptor signaling pathway GO:0007186 136 0.046
detection of stimulus GO:0051606 156 0.046
detection of abiotic stimulus GO:0009582 66 0.045
regulation of mapk cascade GO:0043408 92 0.045
organelle fission GO:0048285 340 0.045
nucleobase containing compound catabolic process GO:0034655 165 0.045
regulation of autophagy GO:0010506 62 0.045
regulation of neuron death GO:1901214 26 0.044
chemical homeostasis GO:0048878 92 0.044
cell adhesion GO:0007155 136 0.044
regulation of phosphorus metabolic process GO:0051174 210 0.044
reactive oxygen species metabolic process GO:0072593 22 0.043
camera type eye development GO:0043010 4 0.043
regulation of wnt signaling pathway GO:0030111 68 0.043
gland development GO:0048732 191 0.043
response to organonitrogen compound GO:0010243 75 0.043
macromolecule catabolic process GO:0009057 161 0.043
negative regulation of biosynthetic process GO:0009890 277 0.042
cellular response to dna damage stimulus GO:0006974 223 0.042
ribonucleoside metabolic process GO:0009119 127 0.042
nucleotide metabolic process GO:0009117 161 0.042
energy derivation by oxidation of organic compounds GO:0015980 32 0.042
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.042
positive regulation of cell migration GO:0030335 2 0.041
cellular response to organic substance GO:0071310 132 0.041
positive regulation of hydrolase activity GO:0051345 78 0.041
positive regulation of apoptotic signaling pathway GO:2001235 4 0.041
molting cycle process GO:0022404 29 0.041
negative regulation of programmed cell death GO:0043069 72 0.041
positive regulation of gene expression GO:0010628 290 0.041
enzyme linked receptor protein signaling pathway GO:0007167 179 0.041
cell growth GO:0016049 108 0.041
positive regulation of multicellular organismal process GO:0051240 143 0.040
cell motility GO:0048870 251 0.040
response to reactive oxygen species GO:0000302 24 0.040
immune system process GO:0002376 347 0.040
regulation of protein phosphorylation GO:0001932 64 0.040
positive regulation of endopeptidase activity GO:0010950 26 0.040
response to biotic stimulus GO:0009607 294 0.040
neuron projection guidance GO:0097485 241 0.039
positive regulation of programmed cell death GO:0043068 62 0.039
cellular response to radiation GO:0071478 52 0.039
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.038
positive regulation of cellular catabolic process GO:0031331 95 0.038
positive regulation of cell communication GO:0010647 250 0.038
organic cyclic compound catabolic process GO:1901361 168 0.038
defense response to other organism GO:0098542 225 0.038
single organism cell adhesion GO:0098602 47 0.038
protein complex biogenesis GO:0070271 201 0.038
cation homeostasis GO:0055080 51 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.037
positive regulation of cellular amine metabolic process GO:0033240 0 0.037
negative regulation of cell death GO:0060548 81 0.037
positive regulation of transcription dna templated GO:0045893 266 0.037
cellular lipid metabolic process GO:0044255 83 0.036
appendage morphogenesis GO:0035107 397 0.036
mapk cascade GO:0000165 107 0.036
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.036
secondary metabolic process GO:0019748 75 0.036
regulation of developmental growth GO:0048638 174 0.036
developmental pigmentation GO:0048066 68 0.036
morphogenesis of a polarized epithelium GO:0001738 93 0.036
response to monosaccharide GO:0034284 4 0.036
small gtpase mediated signal transduction GO:0007264 88 0.036
response to superoxide GO:0000303 3 0.036
amine metabolic process GO:0009308 12 0.036
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.035
cellular amine metabolic process GO:0044106 12 0.035
protein localization GO:0008104 284 0.035
response to extracellular stimulus GO:0009991 116 0.035
ras protein signal transduction GO:0007265 88 0.035
cell proliferation GO:0008283 299 0.034
positive regulation of cell motility GO:2000147 3 0.034
negative regulation of wnt signaling pathway GO:0030178 28 0.034
regulation of cell development GO:0060284 215 0.034
negative regulation of growth GO:0045926 84 0.034
cellular protein localization GO:0034613 160 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.033
extrinsic apoptotic signaling pathway GO:0097191 1 0.033
purine nucleotide catabolic process GO:0006195 109 0.033
autophagy GO:0006914 108 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.033
developmental programmed cell death GO:0010623 138 0.033
learning or memory GO:0007611 141 0.033
mrna metabolic process GO:0016071 124 0.033
cellular nitrogen compound catabolic process GO:0044270 165 0.032
aromatic compound catabolic process GO:0019439 166 0.032
imaginal disc derived appendage development GO:0048737 399 0.032
epidermal growth factor receptor signaling pathway GO:0007173 58 0.032
response to external biotic stimulus GO:0043207 293 0.032
nucleoside triphosphate metabolic process GO:0009141 120 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.032
regulation of cell cycle GO:0051726 291 0.032
regulation of immune system process GO:0002682 176 0.032
negative regulation of cellular biosynthetic process GO:0031327 277 0.032
biological adhesion GO:0022610 138 0.031
glycosyl compound metabolic process GO:1901657 127 0.031
positive regulation of immune system process GO:0002684 68 0.031
ribonucleoside catabolic process GO:0042454 112 0.031
purine nucleoside metabolic process GO:0042278 127 0.031
anatomical structure homeostasis GO:0060249 97 0.031
paracrine signaling GO:0038001 7 0.031
regionalization GO:0003002 416 0.031
single organism carbohydrate metabolic process GO:0044723 72 0.031
negative regulation of gene expression GO:0010629 387 0.030
peptidyl threonine phosphorylation GO:0018107 2 0.030
cellular macromolecule catabolic process GO:0044265 136 0.030
cellular response to oxidative stress GO:0034599 28 0.030
cellular response to nitrogen compound GO:1901699 51 0.030
positive regulation of transport GO:0051050 92 0.030
imaginal disc derived appendage morphogenesis GO:0035114 395 0.030
regulation of cell proliferation GO:0042127 163 0.030
cellular macromolecule localization GO:0070727 220 0.030
regulation of cell morphogenesis GO:0022604 163 0.030
cellular response to peptide hormone stimulus GO:0071375 28 0.029
lipid biosynthetic process GO:0008610 46 0.029
cellular response to lipopolysaccharide GO:0071222 3 0.029
single organism behavior GO:0044708 391 0.029
response to ethanol GO:0045471 59 0.029
purine nucleotide metabolic process GO:0006163 146 0.029
regulation of small gtpase mediated signal transduction GO:0051056 93 0.029
regulation of kinase activity GO:0043549 53 0.029
tube morphogenesis GO:0035239 191 0.029
response to endogenous stimulus GO:0009719 119 0.029
regulation of ras protein signal transduction GO:0046578 93 0.028
dephosphorylation GO:0016311 51 0.028
wing disc morphogenesis GO:0007472 344 0.028
regulation of sequestering of triglyceride GO:0010889 3 0.028
carbohydrate metabolic process GO:0005975 82 0.028
hemopoiesis GO:0030097 46 0.028
membrane organization GO:0061024 112 0.028
phenol containing compound metabolic process GO:0018958 57 0.028
cellular respiration GO:0045333 26 0.028
immune response GO:0006955 246 0.028
myotube cell development GO:0014904 3 0.028
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.028
macromolecular complex assembly GO:0065003 256 0.028
regulation of cellular response to oxidative stress GO:1900407 4 0.028
embryo development ending in birth or egg hatching GO:0009792 152 0.028
negative regulation of rna biosynthetic process GO:1902679 240 0.028
nitrogen compound transport GO:0071705 85 0.027
imaginal disc derived wing vein specification GO:0007474 48 0.027
eggshell formation GO:0030703 105 0.027
protein complex assembly GO:0006461 200 0.027
regulation of protein modification process GO:0031399 112 0.027
cellular response to endogenous stimulus GO:0071495 80 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.027
response to copper ion GO:0046688 4 0.027
negative regulation of cell proliferation GO:0008285 69 0.027
digestive system development GO:0055123 149 0.027
mitochondrion organization GO:0007005 65 0.027
regulation of stress activated mapk cascade GO:0032872 41 0.027
regulation of cytoplasmic transport GO:1903649 47 0.027
ribonucleoside triphosphate metabolic process GO:0009199 119 0.026
chaeta development GO:0022416 97 0.026
ion transport GO:0006811 145 0.026
retina development in camera type eye GO:0060041 4 0.026
cell cycle phase transition GO:0044770 140 0.026
mitotic nuclear division GO:0007067 213 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.026
peptidyl amino acid modification GO:0018193 105 0.026
cellular response to growth factor stimulus GO:0071363 30 0.026
positive regulation of developmental process GO:0051094 143 0.026
adult behavior GO:0030534 137 0.026
response to glucose GO:0009749 2 0.026
nucleoside triphosphate catabolic process GO:0009143 108 0.026
actin filament based process GO:0030029 220 0.026
negative regulation of phosphorus metabolic process GO:0010563 45 0.026
cellular response to molecule of bacterial origin GO:0071219 3 0.026
erbb signaling pathway GO:0038127 58 0.026
gland morphogenesis GO:0022612 145 0.025
regulation of cellular component biogenesis GO:0044087 201 0.025
cell cycle arrest GO:0007050 4 0.025
organic hydroxy compound biosynthetic process GO:1901617 21 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
head involution GO:0008258 35 0.025
metal ion homeostasis GO:0055065 44 0.025
eye photoreceptor cell differentiation GO:0001754 145 0.025
imaginal disc derived leg morphogenesis GO:0007480 80 0.025
glycosyl compound catabolic process GO:1901658 112 0.025
neutral lipid catabolic process GO:0046461 3 0.025
negative regulation of phosphorylation GO:0042326 35 0.025
nucleoside metabolic process GO:0009116 127 0.024
regulation of reactive oxygen species metabolic process GO:2000377 8 0.024
positive regulation of intracellular signal transduction GO:1902533 116 0.024
positive regulation of cellular component organization GO:0051130 156 0.024
single organism cellular localization GO:1902580 180 0.024
regulation of epithelial cell proliferation GO:0050678 4 0.024
nucleoside catabolic process GO:0009164 112 0.024
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.024
guanosine containing compound metabolic process GO:1901068 74 0.024
purine ribonucleotide catabolic process GO:0009154 109 0.024
regulation of steroid metabolic process GO:0019218 2 0.024
somatic muscle development GO:0007525 66 0.024
small molecule biosynthetic process GO:0044283 37 0.024
detection of light stimulus GO:0009583 58 0.024
regulation of protein transport GO:0051223 57 0.023
forebrain development GO:0030900 2 0.023
head development GO:0060322 135 0.023
regulation of hydrolase activity GO:0051336 97 0.023
negative regulation of protein metabolic process GO:0051248 85 0.023
regulation of transferase activity GO:0051338 58 0.023
negative regulation of cellular protein metabolic process GO:0032269 85 0.023
cellular response to peptide GO:1901653 28 0.023
ribose phosphate metabolic process GO:0019693 145 0.023
l amino acid import GO:0043092 2 0.023
regulation of response to oxidative stress GO:1902882 4 0.023
exocrine system development GO:0035272 162 0.023
negative regulation of neuron death GO:1901215 18 0.023
response to peptide hormone GO:0043434 29 0.023
cellular modified amino acid metabolic process GO:0006575 45 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
regulation of peptidase activity GO:0052547 39 0.022
regulation of cell cycle process GO:0010564 181 0.022
transmembrane transport GO:0055085 139 0.022
cellular response to external stimulus GO:0071496 66 0.022
negative regulation of peptide hormone secretion GO:0090278 1 0.022
cation transport GO:0006812 110 0.022
leg disc morphogenesis GO:0007478 80 0.022
positive regulation of apoptotic process GO:0043065 47 0.022
central nervous system development GO:0007417 201 0.022
purine containing compound catabolic process GO:0072523 112 0.022
nucleotide catabolic process GO:0009166 109 0.022
purine containing compound biosynthetic process GO:0072522 30 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.022
metal ion transport GO:0030001 74 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.021
establishment or maintenance of cell polarity GO:0007163 167 0.021
negative regulation of intracellular signal transduction GO:1902532 57 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
body morphogenesis GO:0010171 2 0.021
single organismal cell cell adhesion GO:0016337 45 0.021
defense response to bacterium GO:0042742 178 0.021
negative regulation of developmental growth GO:0048640 64 0.021
regulation of neuron apoptotic process GO:0043523 16 0.021
pigmentation GO:0043473 75 0.021
organophosphate catabolic process GO:0046434 112 0.021
response to hexose GO:0009746 3 0.021
phototransduction GO:0007602 52 0.021
regulation of response to stress GO:0080134 200 0.021
leg disc development GO:0035218 92 0.021
cellular component assembly involved in morphogenesis GO:0010927 151 0.021
cellular response to biotic stimulus GO:0071216 4 0.021
positive regulation of phosphorylation GO:0042327 87 0.021
hindbrain development GO:0030902 2 0.020
salivary gland cell autophagic cell death GO:0035071 83 0.020
cellular homeostasis GO:0019725 80 0.020
regulation of ras gtpase activity GO:0032318 38 0.020
positive regulation of protein phosphorylation GO:0001934 34 0.020
response to ionizing radiation GO:0010212 32 0.020
immune effector process GO:0002252 98 0.020
activation of innate immune response GO:0002218 4 0.020
positive regulation of cell death GO:0010942 69 0.020
jak stat cascade GO:0007259 49 0.020
regulation of neurogenesis GO:0050767 158 0.020
regulation of nucleoside metabolic process GO:0009118 50 0.020
neuron death GO:0070997 27 0.020
cellular response to hexose stimulus GO:0071331 1 0.020
carbohydrate derivative catabolic process GO:1901136 118 0.020
camera type eye morphogenesis GO:0048593 2 0.020
cellular response to nutrient levels GO:0031669 62 0.019
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.019
translation GO:0006412 69 0.019
response to light stimulus GO:0009416 124 0.019
monocarboxylic acid transport GO:0015718 3 0.019
dendrite development GO:0016358 204 0.019
purine nucleoside catabolic process GO:0006152 112 0.019
learning GO:0007612 75 0.019
response to hydrogen peroxide GO:0042542 11 0.019
regulation of purine nucleotide metabolic process GO:1900542 62 0.019
regulation of intracellular transport GO:0032386 64 0.019
positive regulation of nucleic acid templated transcription GO:1903508 266 0.019
pyridine containing compound metabolic process GO:0072524 3 0.019
negative regulation of insulin secretion GO:0046676 1 0.019
regulation of anatomical structure size GO:0090066 163 0.019
regulation of protein localization GO:0032880 76 0.019
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.019
larval development GO:0002164 104 0.019
positive regulation of immune response GO:0050778 63 0.019
neuron apoptotic process GO:0051402 17 0.019
photoreceptor cell differentiation GO:0046530 170 0.019
dendrite morphogenesis GO:0048813 199 0.019
response to peptide GO:1901652 29 0.019
salivary gland histolysis GO:0035070 88 0.018
regulation of purine nucleotide catabolic process GO:0033121 48 0.018
positive regulation of neuron apoptotic process GO:0043525 1 0.018
transmission of nerve impulse GO:0019226 12 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
positive regulation of protein modification process GO:0031401 58 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
positive regulation of lipid metabolic process GO:0045834 4 0.018
wound healing GO:0042060 75 0.018
multicellular organismal homeostasis GO:0048871 41 0.018
intracellular protein transport GO:0006886 104 0.018
cytoplasmic transport GO:0016482 130 0.018
regulation of membrane potential GO:0042391 35 0.018
regulation of nucleotide metabolic process GO:0006140 62 0.018
hormone metabolic process GO:0042445 33 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
protein import into nucleus GO:0006606 51 0.018
developmental maturation GO:0021700 172 0.018
pigment metabolic process GO:0042440 84 0.018
detection of external stimulus GO:0009581 66 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
inorganic ion transmembrane transport GO:0098660 73 0.017
response to insulin GO:0032868 29 0.017
establishment of protein localization GO:0045184 163 0.017
cellular response to starvation GO:0009267 61 0.017
chorion containing eggshell formation GO:0007304 105 0.017
regulation of nucleotide catabolic process GO:0030811 48 0.017
response to organophosphorus GO:0046683 2 0.017
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.017
cellular response to organonitrogen compound GO:0071417 36 0.017
muscle organ development GO:0007517 127 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
cognition GO:0050890 141 0.017
endoderm formation GO:0001706 3 0.017
regulation of multi organism process GO:0043900 131 0.017
immune system development GO:0002520 57 0.017
cellular protein catabolic process GO:0044257 83 0.017
regulation of nervous system development GO:0051960 248 0.017
molting cycle GO:0042303 56 0.017
multi organism behavior GO:0051705 175 0.017

cln3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.130
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.026
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
nervous system disease DOID:863 0 0.024
urinary system disease DOID:18 0 0.018
carbohydrate metabolism disease DOID:0050013 0 0.017
acquired metabolic disease DOID:0060158 0 0.017