Drosophila melanogaster

15 known processes

Npc2c (Dmel_CG3934)

Niemann-Pick type C-2c

(Aliases: Dmel\CG3934,npc2c,DmML5A,CG3934)

Npc2c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gland development GO:0048732 191 0.100
response to biotic stimulus GO:0009607 294 0.095
Fly
response to external biotic stimulus GO:0043207 293 0.084
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.081
phosphatidylethanolamine metabolic process GO:0046337 1 0.079
defense response GO:0006952 300 0.079
Fly
organic acid metabolic process GO:0006082 103 0.078
wing disc morphogenesis GO:0007472 344 0.078
imaginal disc derived appendage development GO:0048737 399 0.070
benzene containing compound metabolic process GO:0042537 3 0.069
appendage development GO:0048736 401 0.068
post embryonic appendage morphogenesis GO:0035120 385 0.067
small molecule metabolic process GO:0044281 305 0.065
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.062
appendage morphogenesis GO:0035107 397 0.061
response to organic substance GO:0010033 284 0.060
negative regulation of gene expression GO:0010629 387 0.060
salivary gland development GO:0007431 162 0.060
gland morphogenesis GO:0022612 145 0.058
oxoacid metabolic process GO:0043436 103 0.058
organonitrogen compound metabolic process GO:1901564 318 0.057
death GO:0016265 284 0.055
endocytosis GO:0006897 310 0.054
vesicle mediated transport GO:0016192 381 0.053
acylglycerol catabolic process GO:0046464 3 0.051
positive regulation of response to stimulus GO:0048584 323 0.050
response to other organism GO:0051707 293 0.049
Fly
catabolic process GO:0009056 409 0.048
regulation of localization GO:0032879 275 0.048
cellular catabolic process GO:0044248 372 0.048
carboxylic acid metabolic process GO:0019752 92 0.047
organic substance catabolic process GO:1901575 308 0.046
cell death GO:0008219 279 0.046
regulation of sequestering of triglyceride GO:0010889 3 0.045
developmental programmed cell death GO:0010623 138 0.044
response to bacterium GO:0009617 198 0.044
Fly
ethanolamine containing compound metabolic process GO:0042439 4 0.043
axon development GO:0061564 297 0.042
response to lipopolysaccharide GO:0032496 4 0.042
exocrine system development GO:0035272 162 0.041
acylglycerol biosynthetic process GO:0046463 2 0.041
single organism biosynthetic process GO:0044711 206 0.041
Fly
salivary gland morphogenesis GO:0007435 145 0.041
dendrite development GO:0016358 204 0.041
positive regulation of lipid storage GO:0010884 4 0.040
morphogenesis of an epithelium GO:0002009 276 0.039
cellular amine metabolic process GO:0044106 12 0.039
phagocytosis GO:0006909 215 0.039
positive regulation of cell communication GO:0010647 250 0.038
secondary metabolic process GO:0019748 75 0.038
triglyceride biosynthetic process GO:0019432 2 0.038
multi organism behavior GO:0051705 175 0.038
phospholipid homeostasis GO:0055091 1 0.038
tissue death GO:0016271 102 0.038
cellular response to organic substance GO:0071310 132 0.037
histolysis GO:0007559 102 0.036
cellular protein modification process GO:0006464 438 0.035
axonogenesis GO:0007409 290 0.035
cholesterol homeostasis GO:0042632 3 0.035
triglyceride catabolic process GO:0019433 3 0.035
negative regulation of cellular metabolic process GO:0031324 382 0.035
positive regulation of signal transduction GO:0009967 223 0.035
mating GO:0007618 120 0.034
cell proliferation GO:0008283 299 0.034
neurological system process GO:0050877 358 0.034
ommochrome metabolic process GO:0046152 19 0.034
cellular ketone metabolic process GO:0042180 24 0.034
Fly
amine metabolic process GO:0009308 12 0.033
neuron recognition GO:0008038 101 0.033
Fly
salivary gland cell autophagic cell death GO:0035071 83 0.033
protein modification process GO:0036211 438 0.033
cellular amino acid metabolic process GO:0006520 61 0.033
tissue morphogenesis GO:0048729 297 0.032
regionalization GO:0003002 416 0.032
organelle fission GO:0048285 340 0.032
forebrain development GO:0030900 2 0.032
response to abiotic stimulus GO:0009628 341 0.031
response to endogenous stimulus GO:0009719 119 0.031
positive regulation of signaling GO:0023056 243 0.031
sterol homeostasis GO:0055092 4 0.031
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.030
cellular response to chemical stimulus GO:0070887 199 0.030
salivary gland histolysis GO:0035070 88 0.030
epithelial cell differentiation GO:0030855 322 0.030
nuclear division GO:0000280 332 0.030
response to copper ion GO:0046688 4 0.030
single organism behavior GO:0044708 391 0.030
ovarian follicle cell development GO:0030707 248 0.030
phosphorylation GO:0016310 294 0.030
immune system process GO:0002376 347 0.029
Fly
neutral lipid catabolic process GO:0046461 3 0.029
phosphatidic acid metabolic process GO:0046473 1 0.029
epithelial cell development GO:0002064 274 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
programmed cell death GO:0012501 257 0.029
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.029
cellular response to endogenous stimulus GO:0071495 80 0.029
gene silencing GO:0016458 138 0.028
response to oxygen containing compound GO:1901700 200 0.028
positive regulation of gene expression GO:0010628 290 0.028
glycerolipid catabolic process GO:0046503 3 0.028
response to extracellular stimulus GO:0009991 116 0.027
positive regulation of transcription dna templated GO:0045893 266 0.027
protein complex biogenesis GO:0070271 201 0.027
single organism catabolic process GO:0044712 228 0.027
secondary metabolite biosynthetic process GO:0044550 24 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
cellular modified amino acid metabolic process GO:0006575 45 0.027
autophagic cell death GO:0048102 83 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.026
positive regulation of rna biosynthetic process GO:1902680 266 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
hormone catabolic process GO:0042447 3 0.026
macromolecular complex assembly GO:0065003 256 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
reproductive behavior GO:0019098 122 0.026
pigmentation GO:0043473 75 0.025
protein localization GO:0008104 284 0.025
regulation of neurogenesis GO:0050767 158 0.025
transcription from rna polymerase ii promoter GO:0006366 368 0.025
cellular macromolecule localization GO:0070727 220 0.025
intracellular signal transduction GO:0035556 300 0.025
growth GO:0040007 359 0.025
negative regulation of cellular biosynthetic process GO:0031327 277 0.025
chromosome organization GO:0051276 360 0.025
body morphogenesis GO:0010171 2 0.025
dendrite morphogenesis GO:0048813 199 0.025
regulation of cell cycle GO:0051726 291 0.025
taxis GO:0042330 304 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.025
neutral lipid biosynthetic process GO:0046460 2 0.024
regulation of transport GO:0051049 181 0.024
proteolysis GO:0006508 192 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
columnar cuboidal epithelial cell development GO:0002066 249 0.024
cellular response to dna damage stimulus GO:0006974 223 0.024
negative regulation of transcription dna templated GO:0045892 237 0.024
ocellus pigmentation GO:0033060 19 0.024
embryonic morphogenesis GO:0048598 206 0.023
positive regulation of rna metabolic process GO:0051254 271 0.023
immune response GO:0006955 246 0.023
Fly
defense response to other organism GO:0098542 225 0.023
Fly
compound eye morphogenesis GO:0001745 249 0.023
mating behavior GO:0007617 106 0.023
response to nutrient levels GO:0031667 114 0.023
anion homeostasis GO:0055081 3 0.023
androgen metabolic process GO:0008209 1 0.023
negative regulation of biosynthetic process GO:0009890 277 0.023
transmembrane transport GO:0055085 139 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
defense response to bacterium GO:0042742 178 0.022
Fly
innate immune response GO:0045087 144 0.022
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.022
negative regulation of response to stimulus GO:0048585 258 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
ion transmembrane transport GO:0034220 122 0.022
regulation of immune system process GO:0002682 176 0.022
regulation of mitotic cell cycle GO:0007346 190 0.022
maintenance of location GO:0051235 73 0.022
xenobiotic catabolic process GO:0042178 1 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.021
cholesterol transport GO:0030301 2 0.021
organic substance transport GO:0071702 257 0.021
Fly
steroid catabolic process GO:0006706 1 0.021
estrogen metabolic process GO:0008210 1 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
courtship behavior GO:0007619 68 0.021
chorion containing eggshell formation GO:0007304 105 0.021
carbohydrate derivative biosynthetic process GO:1901137 85 0.020
mitotic nuclear division GO:0007067 213 0.020
camera type eye development GO:0043010 4 0.020
negative regulation of signaling GO:0023057 219 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
regulation of cell death GO:0010941 173 0.020
chemical homeostasis GO:0048878 92 0.020
Fly
dna metabolic process GO:0006259 227 0.020
gene silencing by rna GO:0031047 57 0.020
response to nitrogen compound GO:1901698 90 0.020
regulation of lipid storage GO:0010883 22 0.020
negative regulation of signal transduction GO:0009968 206 0.020
photoreceptor cell differentiation GO:0046530 170 0.020
imaginal disc pattern formation GO:0007447 91 0.020
developmental growth GO:0048589 280 0.020
regulation of cellular protein metabolic process GO:0032268 243 0.020
protein heterooligomerization GO:0051291 4 0.019
ion transport GO:0006811 145 0.019
pigment metabolic process involved in pigmentation GO:0043474 33 0.019
compound eye photoreceptor cell differentiation GO:0001751 140 0.019
sulfur compound metabolic process GO:0006790 59 0.019
lipid storage GO:0019915 38 0.019
response to alcohol GO:0097305 95 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
response to organophosphorus GO:0046683 2 0.019
neuron projection guidance GO:0097485 241 0.019
compound eye development GO:0048749 307 0.019
mitotic spindle organization GO:0007052 220 0.019
establishment of localization in cell GO:0051649 402 0.019
lateral inhibition GO:0046331 206 0.019
synaptic transmission GO:0007268 288 0.019
immune response activating signal transduction GO:0002757 2 0.019
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
lipid metabolic process GO:0006629 121 0.018
Fly
eggshell formation GO:0030703 105 0.018
wound healing GO:0042060 75 0.018
Fly
negative regulation of developmental process GO:0051093 201 0.018
cell recognition GO:0008037 102 0.018
Fly
response to wounding GO:0009611 94 0.018
Fly
organophosphate metabolic process GO:0019637 195 0.018
positive regulation of sequestering of triglyceride GO:0010890 1 0.018
lipid localization GO:0010876 54 0.018
Fly
dorsal ventral pattern formation GO:0009953 133 0.018
regulation of synapse structure and activity GO:0050803 128 0.018
single organism intracellular transport GO:1902582 207 0.018
negative regulation of cell cycle process GO:0010948 109 0.018
response to organic cyclic compound GO:0014070 89 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
alditol phosphate metabolic process GO:0052646 2 0.018
adult behavior GO:0030534 137 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
axon guidance GO:0007411 233 0.017
aggressive behavior GO:0002118 63 0.017
cellular response to hormone stimulus GO:0032870 44 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
synapse organization GO:0050808 196 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
humoral immune response GO:0006959 117 0.017
Fly
sensory organ morphogenesis GO:0090596 260 0.017
regulation of epithelial cell differentiation GO:0030856 4 0.017
regulation of neuron differentiation GO:0045664 103 0.017
long chain fatty acid metabolic process GO:0001676 3 0.017
tube morphogenesis GO:0035239 191 0.017
protein complex assembly GO:0006461 200 0.017
intracellular transport GO:0046907 228 0.017
synapse assembly GO:0007416 143 0.017
regulation of nervous system development GO:0051960 248 0.017
central nervous system development GO:0007417 201 0.017
gliogenesis GO:0042063 80 0.017
regulation of organelle organization GO:0033043 196 0.017
negative regulation of cell communication GO:0010648 223 0.017
non sensory hair organization GO:0035316 47 0.016
regulation of sterol transport GO:0032371 1 0.016
regulation of mitotic cell cycle phase transition GO:1901990 130 0.016
regulation of cell cycle process GO:0010564 181 0.016
immune response regulating signaling pathway GO:0002764 2 0.016
ocellus pigment biosynthetic process GO:0008055 19 0.016
chaeta development GO:0022416 97 0.016
phosphatidylcholine metabolic process GO:0046470 3 0.016
protein maturation GO:0051604 71 0.016
mitotic cell cycle phase transition GO:0044772 138 0.016
circadian rhythm GO:0007623 105 0.016
regulation of multi organism process GO:0043900 131 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
respiratory system development GO:0060541 213 0.016
developmental maturation GO:0021700 172 0.016
regulation of protein metabolic process GO:0051246 256 0.016
regulation of response to stress GO:0080134 200 0.016
chromatin modification GO:0016568 147 0.016
neurotransmitter metabolic process GO:0042133 2 0.016
eye morphogenesis GO:0048592 260 0.016
cell cycle checkpoint GO:0000075 95 0.016
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
cell motility GO:0048870 251 0.016
heterocycle catabolic process GO:0046700 166 0.016
mitotic dna integrity checkpoint GO:0044774 75 0.016
anterior posterior pattern specification GO:0009952 136 0.016
wnt signaling pathway GO:0016055 98 0.016
axis specification GO:0009798 167 0.015
chromatin organization GO:0006325 207 0.015
establishment of tissue polarity GO:0007164 87 0.015
retina development in camera type eye GO:0060041 4 0.015
nephron tubule morphogenesis GO:0072078 3 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
regulation of lipid transport GO:0032368 3 0.015
acetylcholine catabolic process GO:0006581 1 0.015
organophosphate catabolic process GO:0046434 112 0.015
meiotic cell cycle GO:0051321 171 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.015
organelle localization GO:0051640 148 0.015
homeostatic process GO:0042592 199 0.015
Fly
defense response to gram negative bacterium GO:0050829 94 0.015
mitotic g2 m transition checkpoint GO:0044818 70 0.015
regulation of cell cycle phase transition GO:1901987 130 0.015
mitotic cell cycle checkpoint GO:0007093 88 0.015
hindbrain development GO:0030902 2 0.015
nephron tubule development GO:0072080 3 0.015
mitotic dna damage checkpoint GO:0044773 74 0.015
photoreceptor cell development GO:0042461 96 0.015
ameboidal type cell migration GO:0001667 151 0.015
secretion by cell GO:0032940 101 0.015
chromosome segregation GO:0007059 157 0.015
multi multicellular organism process GO:0044706 123 0.015
cellular protein localization GO:0034613 160 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
limb morphogenesis GO:0035108 1 0.015
limb development GO:0060173 1 0.014
aromatic compound catabolic process GO:0019439 166 0.014
telencephalon development GO:0021537 2 0.014
dna integrity checkpoint GO:0031570 81 0.014
regulation of cell differentiation GO:0045595 302 0.014
eye development GO:0001654 323 0.014
stem cell differentiation GO:0048863 117 0.014
cellular response to carbohydrate stimulus GO:0071322 4 0.014
eye photoreceptor cell development GO:0042462 81 0.014
protein processing GO:0016485 68 0.014
single organism cellular localization GO:1902580 180 0.014
connective tissue development GO:0061448 3 0.014
genital disc development GO:0035215 44 0.014
nephron epithelium development GO:0072009 3 0.014
cell cycle phase transition GO:0044770 140 0.014
actin filament based process GO:0030029 220 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
negative regulation of cell cycle GO:0045786 116 0.014
imaginal disc derived wing hair organization GO:0035317 45 0.014
regulation of phosphorylation GO:0042325 147 0.014
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.014
cell division GO:0051301 248 0.014
autophagy GO:0006914 108 0.014
cellular response to ethanol GO:0071361 4 0.014
kidney development GO:0001822 3 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
multicellular organismal reproductive behavior GO:0033057 110 0.014
response to hormone GO:0009725 45 0.014
apoptotic process GO:0006915 159 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
positive regulation of transport GO:0051050 92 0.014
segmentation GO:0035282 207 0.014
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
male mating behavior GO:0060179 70 0.013
mapk cascade GO:0000165 107 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
regulation of molecular function GO:0065009 217 0.013
g2 dna damage checkpoint GO:0031572 69 0.013
camera type eye morphogenesis GO:0048593 2 0.013
nephron development GO:0072006 3 0.013
localization of cell GO:0051674 257 0.013
tube development GO:0035295 244 0.013
small molecule biosynthetic process GO:0044283 37 0.013
Fly
regulation of apoptotic process GO:0042981 130 0.013
spindle organization GO:0007051 253 0.013
brain development GO:0007420 120 0.013
innate immune response activating signal transduction GO:0002758 2 0.013
response to organonitrogen compound GO:0010243 75 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
nephron epithelium morphogenesis GO:0072088 3 0.013
dna damage checkpoint GO:0000077 78 0.013
open tracheal system development GO:0007424 204 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
kidney morphogenesis GO:0060993 3 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of cell proliferation GO:0042127 163 0.013
mitotic cytokinesis GO:0000281 50 0.013
positive regulation of cell migration GO:0030335 2 0.013
peptidyl amino acid modification GO:0018193 105 0.013
response to hexose GO:0009746 3 0.013
cytokinesis GO:0000910 90 0.013
positive regulation of cell death GO:0010942 69 0.013
regulation of mapk cascade GO:0043408 92 0.013
protein phosphorylation GO:0006468 169 0.013
membrane organization GO:0061024 112 0.013
peptide metabolic process GO:0006518 80 0.013
kidney epithelium development GO:0072073 3 0.013
anterior posterior axis specification GO:0009948 109 0.013
organic cyclic compound catabolic process GO:1901361 168 0.012
chemotaxis GO:0006935 249 0.012
antimicrobial humoral response GO:0019730 99 0.012
cognition GO:0050890 141 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.012
macromolecule catabolic process GO:0009057 161 0.012
cellular biogenic amine catabolic process GO:0042402 1 0.012
response to oxygen levels GO:0070482 59 0.012
morphogenesis of a polarized epithelium GO:0001738 93 0.012
membrane depolarization GO:0051899 4 0.012
adult locomotory behavior GO:0008344 76 0.012
positive regulation of cell motility GO:2000147 3 0.012
regulation of programmed cell death GO:0043067 152 0.012
locomotory behavior GO:0007626 176 0.012
regulation of epithelial cell proliferation GO:0050678 4 0.012
positive regulation of exocytosis GO:0045921 4 0.012
inorganic ion transmembrane transport GO:0098660 73 0.012
meiotic chromosome segregation GO:0045132 59 0.012
embryonic axis specification GO:0000578 107 0.012
rna localization GO:0006403 115 0.012
nephron morphogenesis GO:0072028 3 0.012
cellular lipid metabolic process GO:0044255 83 0.012
mitotic g2 dna damage checkpoint GO:0007095 69 0.012
cytoplasmic transport GO:0016482 130 0.012
l glutamate import GO:0051938 1 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
cellular amide metabolic process GO:0043603 80 0.012
regulation of wnt signaling pathway GO:0030111 68 0.012
amine catabolic process GO:0009310 1 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
long chain fatty acid biosynthetic process GO:0042759 1 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
response to light stimulus GO:0009416 124 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
regulation of hormone levels GO:0010817 40 0.012
Fly
eye pigment metabolic process GO:0042441 33 0.012
pheromone biosynthetic process GO:0042811 3 0.012
regulation of cell development GO:0060284 215 0.012
inter male aggressive behavior GO:0002121 60 0.012
cell projection assembly GO:0030031 94 0.012
eye pigmentation GO:0048069 43 0.012
cell adhesion GO:0007155 136 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
tripartite regional subdivision GO:0007351 103 0.012
regulation of cellular localization GO:0060341 136 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
male gamete generation GO:0048232 201 0.012
regulation of cellular response to stress GO:0080135 89 0.012
ras protein signal transduction GO:0007265 88 0.012
protein transport GO:0015031 155 0.012
cellular response to monosaccharide stimulus GO:0071326 2 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
regulation of catalytic activity GO:0050790 185 0.011
nucleotide metabolic process GO:0009117 161 0.011
pigment biosynthetic process GO:0046148 36 0.011
ocellus pigment metabolic process GO:0046158 19 0.011
meiotic nuclear division GO:0007126 151 0.011
regulation of immune response GO:0050776 118 0.011
hindgut morphogenesis GO:0007442 58 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
peripheral nervous system development GO:0007422 52 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
establishment of protein localization GO:0045184 163 0.011
organelle fusion GO:0048284 46 0.011
olfactory behavior GO:0042048 97 0.011
cell maturation GO:0048469 144 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
response to temperature stimulus GO:0009266 106 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
covalent chromatin modification GO:0016569 106 0.011
endomembrane system organization GO:0010256 119 0.011
rrna processing GO:0006364 3 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
carbohydrate metabolic process GO:0005975 82 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
establishment of planar polarity GO:0001736 87 0.011
regulation of synapse organization GO:0050807 110 0.011
acetate ester metabolic process GO:1900619 2 0.011
peptidyl lysine modification GO:0018205 57 0.011
response to radiation GO:0009314 155 0.011
embryonic pattern specification GO:0009880 174 0.011
negative regulation of insulin secretion GO:0046676 1 0.011
spindle elongation GO:0051231 83 0.011
compound eye photoreceptor development GO:0042051 78 0.011
photoreceptor cell fate commitment GO:0046552 41 0.011
negative regulation of homeostatic process GO:0032845 2 0.011
dorsal ventral axis specification GO:0009950 66 0.011
anatomical structure homeostasis GO:0060249 97 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
response to decreased oxygen levels GO:0036293 58 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
vitamin metabolic process GO:0006766 2 0.011
lipid biosynthetic process GO:0008610 46 0.011
Fly
rna processing GO:0006396 147 0.011
hair cell differentiation GO:0035315 47 0.011
acetylcholine metabolic process GO:0008291 2 0.011
neuropeptide signaling pathway GO:0007218 45 0.011
glycoprotein biosynthetic process GO:0009101 41 0.011
leg disc development GO:0035218 92 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.010

Npc2c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.077
familial hyperlipidemia DOID:1168 0 0.077
lipid metabolism disorder DOID:3146 0 0.077
familial combined hyperlipidemia DOID:13809 0 0.077
inherited metabolic disorder DOID:655 0 0.077
familial hypertriglyceridemia DOID:0050527 0 0.075
acquired metabolic disease DOID:0060158 0 0.071
disease of anatomical entity DOID:7 0 0.054
familial lipoprotein lipase deficiency DOID:14118 0 0.052
hair disease DOID:421 0 0.052
integumentary system disease DOID:16 0 0.052
hypotrichosis DOID:4535 0 0.052
carbohydrate metabolism disease DOID:0050013 0 0.027
glucose metabolism disease DOID:4194 0 0.027
diabetes mellitus DOID:9351 0 0.022
type 2 diabetes mellitus DOID:9352 0 0.022
hypophosphatasia DOID:14213 0 0.019
nervous system disease DOID:863 0 0.016
cardiovascular system disease DOID:1287 0 0.015
sensory system disease DOID:0050155 0 0.015
musculoskeletal system disease DOID:17 0 0.013