Drosophila melanogaster

37 known processes

emp (Dmel_CG2727)

epithelial membrane protein

(Aliases: Dmel\CG2727,CG2727)

emp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to abiotic stimulus GO:0009628 341 0.163
Fly
carboxylic acid metabolic process GO:0019752 92 0.121
response to radiation GO:0009314 155 0.090
Fly
lipid metabolic process GO:0006629 121 0.081
Rat Fly
phagocytosis GO:0006909 215 0.081
Human Rat
long chain fatty acid metabolic process GO:0001676 3 0.078
very long chain fatty acid metabolic process GO:0000038 4 0.076
organic acid metabolic process GO:0006082 103 0.072
appendage morphogenesis GO:0035107 397 0.063
cell death GO:0008219 279 0.063
cellular protein modification process GO:0006464 438 0.061
regulation of hormone levels GO:0010817 40 0.061
Rat
very long chain fatty acid biosynthetic process GO:0042761 2 0.058
response to external biotic stimulus GO:0043207 293 0.057
Human
organonitrogen compound metabolic process GO:1901564 318 0.056
detection of stimulus GO:0051606 156 0.056
Human Fly
appendage development GO:0048736 401 0.055
single organism biosynthetic process GO:0044711 206 0.051
Rat Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.049
post embryonic appendage morphogenesis GO:0035120 385 0.049
homeostatic process GO:0042592 199 0.046
defense response to other organism GO:0098542 225 0.046
negative regulation of gene expression GO:0010629 387 0.046
cellular lipid metabolic process GO:0044255 83 0.045
Fly
organonitrogen compound biosynthetic process GO:1901566 117 0.043
small molecule biosynthetic process GO:0044283 37 0.042
ovarian follicle cell development GO:0030707 248 0.042
regulation of protein metabolic process GO:0051246 256 0.042
long chain fatty acid biosynthetic process GO:0042759 1 0.040
microtubule organizing center organization GO:0031023 168 0.040
vitamin metabolic process GO:0006766 2 0.039
regulation of cell death GO:0010941 173 0.038
tube morphogenesis GO:0035239 191 0.038
immune system process GO:0002376 347 0.036
Human
regulation of molecular function GO:0065009 217 0.035
Human
wing disc morphogenesis GO:0007472 344 0.035
monocarboxylic acid metabolic process GO:0032787 29 0.035
connective tissue development GO:0061448 3 0.034
regulation of cellular protein metabolic process GO:0032268 243 0.034
neuron recognition GO:0008038 101 0.034
apoptotic process GO:0006915 159 0.034
regulation of cell cycle GO:0051726 291 0.034
regulation of localization GO:0032879 275 0.034
Human Rat
small molecule metabolic process GO:0044281 305 0.033
regulation of catalytic activity GO:0050790 185 0.032
Human
intracellular signal transduction GO:0035556 300 0.032
response to bacterium GO:0009617 198 0.030
Human
positive regulation of response to stimulus GO:0048584 323 0.030
Human
spindle organization GO:0007051 253 0.030
lipid biosynthetic process GO:0008610 46 0.029
Rat
kidney development GO:0001822 3 0.029
detection of external stimulus GO:0009581 66 0.027
Fly
mating behavior GO:0007617 106 0.027
cellular response to radiation GO:0071478 52 0.027
Fly
protein modification process GO:0036211 438 0.027
phosphorylation GO:0016310 294 0.027
imaginal disc derived appendage morphogenesis GO:0035114 395 0.027
fatty acid elongation unsaturated fatty acid GO:0019368 1 0.026
imaginal disc derived appendage development GO:0048737 399 0.026
organic substance transport GO:0071702 257 0.026
Human Rat Fly
single organism catabolic process GO:0044712 228 0.026
neurological system process GO:0050877 358 0.026
catabolic process GO:0009056 409 0.026
secondary metabolite biosynthetic process GO:0044550 24 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
cell proliferation GO:0008283 299 0.025
open tracheal system development GO:0007424 204 0.025
regulation of transport GO:0051049 181 0.025
Rat
positive regulation of signal transduction GO:0009967 223 0.024
response to biotic stimulus GO:0009607 294 0.023
Human
organic substance catabolic process GO:1901575 308 0.023
programmed cell death GO:0012501 257 0.023
phototransduction GO:0007602 52 0.022
Fly
cellular catabolic process GO:0044248 372 0.022
defense response to bacterium GO:0042742 178 0.021
oxoacid metabolic process GO:0043436 103 0.021
endocytosis GO:0006897 310 0.021
Human Rat Fly
death GO:0016265 284 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
renal system development GO:0072001 72 0.021
carboxylic acid biosynthetic process GO:0046394 15 0.021
cellular response to chemical stimulus GO:0070887 199 0.020
Human
response to other organism GO:0051707 293 0.020
Human
cellular protein localization GO:0034613 160 0.020
chemical homeostasis GO:0048878 92 0.020
negative regulation of cell death GO:0060548 81 0.020
ras protein signal transduction GO:0007265 88 0.020
sensory organ morphogenesis GO:0090596 260 0.020
cellular macromolecule localization GO:0070727 220 0.020
cell migration GO:0016477 238 0.020
response to organic substance GO:0010033 284 0.020
Human
vesicle mediated transport GO:0016192 381 0.020
Human Rat Fly
lipid localization GO:0010876 54 0.020
Human Rat Fly
respiratory system development GO:0060541 213 0.020
positive regulation of cell communication GO:0010647 250 0.020
spindle assembly GO:0051225 80 0.020
cell division GO:0051301 248 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
secondary metabolic process GO:0019748 75 0.019
synaptic target recognition GO:0008039 45 0.019
regulation of cell differentiation GO:0045595 302 0.019
negative regulation of extracellular matrix disassembly GO:0010716 1 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
organelle assembly GO:0070925 198 0.019
positive regulation of molecular function GO:0044093 136 0.019
Human
organelle fission GO:0048285 340 0.019
aging GO:0007568 143 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
epithelial cell differentiation GO:0030855 322 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
meiotic nuclear division GO:0007126 151 0.018
macromolecular complex assembly GO:0065003 256 0.018
regulation of cell development GO:0060284 215 0.017
defense response GO:0006952 300 0.017
regulation of programmed cell death GO:0043067 152 0.017
rhodopsin metabolic process GO:0046154 10 0.017
Fly
single organism cellular localization GO:1902580 180 0.017
response to oxygen containing compound GO:1901700 200 0.017
Human
cell motility GO:0048870 251 0.017
mesoderm development GO:0007498 78 0.017
eye morphogenesis GO:0048592 260 0.017
response to extracellular stimulus GO:0009991 116 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
actin cytoskeleton organization GO:0030036 206 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
epithelium migration GO:0090132 148 0.016
centrosome organization GO:0051297 163 0.016
positive regulation of signaling GO:0023056 243 0.016
sterol homeostasis GO:0055092 4 0.016
actin filament based process GO:0030029 220 0.016
mating GO:0007618 120 0.016
biological adhesion GO:0022610 138 0.016
Human
segmentation GO:0035282 207 0.016
fatty acid elongation GO:0030497 3 0.016
meiotic cell cycle GO:0051321 171 0.016
regulation of mitotic cell cycle GO:0007346 190 0.015
regionalization GO:0003002 416 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
nuclear division GO:0000280 332 0.015
ovarian follicle cell migration GO:0007297 121 0.015
response to reactive oxygen species GO:0000302 24 0.015
single organism intracellular transport GO:1902582 207 0.015
protein phosphorylation GO:0006468 169 0.015
aromatic compound catabolic process GO:0019439 166 0.015
regulation of hydrolase activity GO:0051336 97 0.015
regulation of tube architecture open tracheal system GO:0035152 68 0.015
taxis GO:0042330 304 0.015
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
epithelial cell development GO:0002064 274 0.015
regulation of apoptotic process GO:0042981 130 0.014
maintenance of location GO:0051235 73 0.014
Human
negative regulation of cell communication GO:0010648 223 0.014
axonogenesis GO:0007409 290 0.014
response to nutrient levels GO:0031667 114 0.014
organic acid biosynthetic process GO:0016053 15 0.014
negative regulation of cell cycle phase transition GO:1901988 103 0.014
response to ionizing radiation GO:0010212 32 0.014
heart development GO:0007507 82 0.014
cellular amine metabolic process GO:0044106 12 0.014
body morphogenesis GO:0010171 2 0.014
response to lipopolysaccharide GO:0032496 4 0.014
Human
response to oxidative stress GO:0006979 86 0.014
organonitrogen compound catabolic process GO:1901565 128 0.013
tissue migration GO:0090130 155 0.013
axis specification GO:0009798 167 0.013
detection of abiotic stimulus GO:0009582 66 0.013
Fly
regulation of neuron differentiation GO:0045664 103 0.013
cellular response to abiotic stimulus GO:0071214 58 0.013
Fly
tissue morphogenesis GO:0048729 297 0.013
camera type eye development GO:0043010 4 0.013
xenobiotic catabolic process GO:0042178 1 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
regulation of intracellular transport GO:0032386 64 0.013
synaptic transmission GO:0007268 288 0.013
regulation of nervous system development GO:0051960 248 0.013
male gamete generation GO:0048232 201 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.013
cytoskeleton dependent cytokinesis GO:0061640 81 0.013
stem cell differentiation GO:0048863 117 0.013
amine metabolic process GO:0009308 12 0.013
lateral inhibition GO:0046331 206 0.013
neuron projection guidance GO:0097485 241 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
tube formation GO:0035148 21 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
fatty acid metabolic process GO:0006631 20 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
regulation of response to stress GO:0080134 200 0.012
Human
protein localization GO:0008104 284 0.012
forebrain development GO:0030900 2 0.012
immune effector process GO:0002252 98 0.012
reproductive behavior GO:0019098 122 0.012
compound eye morphogenesis GO:0001745 249 0.012
cytokinesis GO:0000910 90 0.012
response to organophosphorus GO:0046683 2 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
negative regulation of extracellular matrix organization GO:1903054 1 0.012
cell recognition GO:0008037 102 0.012
Human Rat
protein complex assembly GO:0006461 200 0.012
multi organism reproductive behavior GO:0044705 121 0.012
gland development GO:0048732 191 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
regulation of defense response GO:0031347 102 0.011
Human
positive regulation of lipid storage GO:0010884 4 0.011
Human
skin development GO:0043588 65 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
Human
axon development GO:0061564 297 0.011
antimicrobial humoral response GO:0019730 99 0.011
pigmentation GO:0043473 75 0.011
Fly
carbohydrate derivative metabolic process GO:1901135 217 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
androgen metabolic process GO:0008209 1 0.011
Rat
response to glucose GO:0009749 2 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
cellular ketone metabolic process GO:0042180 24 0.011
protein localization to organelle GO:0033365 82 0.011
response to alcohol GO:0097305 95 0.011
protein complex biogenesis GO:0070271 201 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
cell adhesion GO:0007155 136 0.011
epithelial cell migration GO:0010631 148 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
eye development GO:0001654 323 0.010
cytoplasmic transport GO:0016482 130 0.010
spermatogenesis GO:0007283 200 0.010
localization of cell GO:0051674 257 0.010
positive regulation of cellular biosynthetic process GO:0031328 316 0.010
regulation of neurogenesis GO:0050767 158 0.010
synapse assembly GO:0007416 143 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
regulation of proteolysis GO:0030162 87 0.010
blastoderm segmentation GO:0007350 159 0.010
regulation of cellular catabolic process GO:0031329 157 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
negative regulation of developmental process GO:0051093 201 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.010

emp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.129
nervous system disease DOID:863 0 0.041
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
musculoskeletal system disease DOID:17 0 0.013
central nervous system disease DOID:331 0 0.011
neurodegenerative disease DOID:1289 0 0.011