Drosophila melanogaster

77 known processes

tomb (Dmel_CG14016)

tombola

(Aliases: Tomb,Dmel\CG14016,CG14016)

tomb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 151 0.526
meiosis i GO:0007127 59 0.373
nuclear division GO:0000280 332 0.362
meiotic cell cycle GO:0051321 171 0.316
meiotic cell cycle process GO:1903046 132 0.249
organelle fission GO:0048285 340 0.127
positive regulation of rna metabolic process GO:0051254 271 0.110
positive regulation of transcription dna templated GO:0045893 266 0.105
positive regulation of gene expression GO:0010628 290 0.104
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.098
positive regulation of nucleic acid templated transcription GO:1903508 266 0.097
positive regulation of biosynthetic process GO:0009891 316 0.093
positive regulation of cellular biosynthetic process GO:0031328 316 0.088
positive regulation of rna biosynthetic process GO:1902680 266 0.086
imaginal disc derived appendage development GO:0048737 399 0.074
male gamete generation GO:0048232 201 0.063
imaginal disc derived wing morphogenesis GO:0007476 337 0.060
imaginal disc derived appendage morphogenesis GO:0035114 395 0.058
meiosis ii GO:0007135 23 0.058
meiotic cytokinesis GO:0033206 33 0.058
appendage development GO:0048736 401 0.058
appendage morphogenesis GO:0035107 397 0.057
positive regulation of macromolecule metabolic process GO:0010604 405 0.054
male meiosis GO:0007140 52 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.049
wing disc morphogenesis GO:0007472 344 0.046
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.045
transcription from rna polymerase ii promoter GO:0006366 368 0.043
chromosome organization GO:0051276 360 0.043
small molecule metabolic process GO:0044281 305 0.038
regulation of localization GO:0032879 275 0.038
regionalization GO:0003002 416 0.037
post embryonic appendage morphogenesis GO:0035120 385 0.037
regulation of microtubule based process GO:0032886 49 0.036
macromolecular complex assembly GO:0065003 256 0.035
regulation of multicellular organismal development GO:2000026 414 0.035
regulation of cellular protein metabolic process GO:0032268 243 0.034
single organism behavior GO:0044708 391 0.034
organonitrogen compound metabolic process GO:1901564 318 0.034
cell division GO:0051301 248 0.033
cellular protein modification process GO:0006464 438 0.032
body morphogenesis GO:0010171 2 0.032
protein depolymerization GO:0051261 31 0.031
eye photoreceptor cell differentiation GO:0001754 145 0.030
columnar cuboidal epithelial cell development GO:0002066 249 0.030
neurological system process GO:0050877 358 0.030
salivary gland morphogenesis GO:0007435 145 0.030
negative regulation of cellular metabolic process GO:0031324 382 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.030
taxis GO:0042330 304 0.029
nucleobase containing small molecule metabolic process GO:0055086 174 0.029
cell migration GO:0016477 238 0.029
vesicle mediated transport GO:0016192 381 0.029
male meiosis i GO:0007141 9 0.028
photoreceptor cell differentiation GO:0046530 170 0.028
protein localization GO:0008104 284 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.027
developmental growth GO:0048589 280 0.027
exocrine system development GO:0035272 162 0.027
regulation of cell cycle process GO:0010564 181 0.026
salivary gland development GO:0007431 162 0.026
positive regulation of cell communication GO:0010647 250 0.026
forebrain development GO:0030900 2 0.026
pigmentation GO:0043473 75 0.026
gland morphogenesis GO:0022612 145 0.026
cytoskeleton dependent cytokinesis GO:0061640 81 0.026
microtubule based transport GO:0010970 42 0.026
sister chromatid segregation GO:0000819 92 0.026
segmentation GO:0035282 207 0.025
posttranscriptional regulation of gene expression GO:0010608 145 0.025
meiotic spindle organization GO:0000212 36 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
regulation of protein metabolic process GO:0051246 256 0.025
histolysis GO:0007559 102 0.025
regulation of cellular component biogenesis GO:0044087 201 0.025
establishment of localization in cell GO:0051649 402 0.024
response to glucose GO:0009749 2 0.024
gland development GO:0048732 191 0.024
blastoderm segmentation GO:0007350 159 0.024
response to organic substance GO:0010033 284 0.024
developmental programmed cell death GO:0010623 138 0.023
oxoacid metabolic process GO:0043436 103 0.023
nucleobase containing compound catabolic process GO:0034655 165 0.023
chromosome segregation GO:0007059 157 0.023
positive regulation of cell migration GO:0030335 2 0.023
homeostatic process GO:0042592 199 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.022
eye morphogenesis GO:0048592 260 0.022
kidney development GO:0001822 3 0.022
cellular catabolic process GO:0044248 372 0.022
cell cycle phase transition GO:0044770 140 0.021
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
nucleoside metabolic process GO:0009116 127 0.021
compound eye development GO:0048749 307 0.021
camera type eye development GO:0043010 4 0.021
negative regulation of microtubule depolymerization GO:0007026 21 0.021
negative regulation of developmental process GO:0051093 201 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
endocytosis GO:0006897 310 0.021
compound eye morphogenesis GO:0001745 249 0.021
regulation of anatomical structure size GO:0090066 163 0.020
purine containing compound metabolic process GO:0072521 155 0.020
regulation of protein complex disassembly GO:0043244 29 0.020
aromatic compound catabolic process GO:0019439 166 0.020
connective tissue development GO:0061448 3 0.020
catabolic process GO:0009056 409 0.020
single organism catabolic process GO:0044712 228 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
tissue death GO:0016271 102 0.020
embryonic development via the syncytial blastoderm GO:0001700 148 0.020
phagocytosis GO:0006909 215 0.020
cell death GO:0008219 279 0.020
intracellular signal transduction GO:0035556 300 0.020
anatomical structure homeostasis GO:0060249 97 0.020
response to oxygen containing compound GO:1901700 200 0.020
positive regulation of signaling GO:0023056 243 0.020
response to hexose GO:0009746 3 0.020
organophosphate metabolic process GO:0019637 195 0.020
carboxylic acid metabolic process GO:0019752 92 0.019
purine ribonucleoside catabolic process GO:0046130 112 0.019
purine nucleoside catabolic process GO:0006152 112 0.019
response to monosaccharide GO:0034284 4 0.019
single organism biosynthetic process GO:0044711 206 0.019
organic substance catabolic process GO:1901575 308 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
programmed cell death GO:0012501 257 0.019
eye development GO:0001654 323 0.019
reproductive behavior GO:0019098 122 0.019
organic acid metabolic process GO:0006082 103 0.019
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
regulation of translation GO:0006417 56 0.019
ovarian follicle cell development GO:0030707 248 0.019
detection of stimulus GO:0051606 156 0.019
open tracheal system development GO:0007424 204 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
adult behavior GO:0030534 137 0.019
regulation of cell cycle GO:0051726 291 0.019
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.018
cellular protein complex disassembly GO:0043624 35 0.018
cellular amine metabolic process GO:0044106 12 0.018
negative regulation of cytoskeleton organization GO:0051494 30 0.018
negative regulation of gene expression GO:0010629 387 0.018
embryonic pattern specification GO:0009880 174 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.018
regulation of cell differentiation GO:0045595 302 0.018
purine nucleotide catabolic process GO:0006195 109 0.018
regulation of imaginal disc derived wing size GO:0044719 20 0.018
growth GO:0040007 359 0.018
telencephalon development GO:0021537 2 0.018
gene silencing GO:0016458 138 0.018
spermatogenesis GO:0007283 200 0.018
cytokinesis GO:0000910 90 0.018
multi organism behavior GO:0051705 175 0.017
salivary gland cell autophagic cell death GO:0035071 83 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
androgen metabolic process GO:0008209 1 0.017
anterior posterior pattern specification GO:0009952 136 0.017
spermatid differentiation GO:0048515 114 0.017
cellular macromolecule localization GO:0070727 220 0.017
response to other organism GO:0051707 293 0.017
cellular component assembly involved in morphogenesis GO:0010927 151 0.017
kidney epithelium development GO:0072073 3 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
cell proliferation GO:0008283 299 0.017
multicellular organismal reproductive behavior GO:0033057 110 0.017
ribonucleoside catabolic process GO:0042454 112 0.017
purine nucleoside triphosphate metabolic process GO:0009144 119 0.017
nucleotide metabolic process GO:0009117 161 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
morphogenesis of an epithelium GO:0002009 276 0.016
autophagic cell death GO:0048102 83 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
actin filament based process GO:0030029 220 0.016
nucleoside triphosphate catabolic process GO:0009143 108 0.016
regulation of transport GO:0051049 181 0.016
heterocycle catabolic process GO:0046700 166 0.016
organic substance transport GO:0071702 257 0.016
axon development GO:0061564 297 0.016
positive regulation of cell motility GO:2000147 3 0.016
localization of cell GO:0051674 257 0.016
cellular ketone metabolic process GO:0042180 24 0.016
axon guidance GO:0007411 233 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
ras protein signal transduction GO:0007265 88 0.016
anterior posterior axis specification GO:0009948 109 0.016
translation GO:0006412 69 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
axis specification GO:0009798 167 0.016
regulation of nervous system development GO:0051960 248 0.016
amine metabolic process GO:0009308 12 0.016
single organism intracellular transport GO:1902582 207 0.015
axonogenesis GO:0007409 290 0.015
phosphorylation GO:0016310 294 0.015
chromatin organization GO:0006325 207 0.015
immune system process GO:0002376 347 0.015
ameboidal type cell migration GO:0001667 151 0.015
kidney morphogenesis GO:0060993 3 0.015
chemotaxis GO:0006935 249 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
very long chain fatty acid metabolic process GO:0000038 4 0.015
dendrite development GO:0016358 204 0.015
olfactory behavior GO:0042048 97 0.015
regulation of response to stress GO:0080134 200 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
cell motility GO:0048870 251 0.015
apoptotic process GO:0006915 159 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
regulation of growth GO:0040008 233 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
spindle organization GO:0007051 253 0.014
intracellular transport GO:0046907 228 0.014
tissue morphogenesis GO:0048729 297 0.014
regulation of catalytic activity GO:0050790 185 0.014
male meiosis cytokinesis GO:0007112 26 0.014
single organism cellular localization GO:1902580 180 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
respiratory system development GO:0060541 213 0.014
spermatocyte division GO:0048137 13 0.014
protein modification process GO:0036211 438 0.014
stem cell proliferation GO:0072089 88 0.014
limb development GO:0060173 1 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
tube development GO:0035295 244 0.014
regulation of microtubule depolymerization GO:0031114 24 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
cellular response to organic substance GO:0071310 132 0.014
embryonic morphogenesis GO:0048598 206 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
nephron development GO:0072006 3 0.014
photoreceptor cell development GO:0042461 96 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
tripartite regional subdivision GO:0007351 103 0.014
secretion GO:0046903 109 0.014
regulation of spindle organization GO:0090224 17 0.014
hematopoietic progenitor cell differentiation GO:0002244 1 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
response to lipopolysaccharide GO:0032496 4 0.014
nephron tubule development GO:0072080 3 0.014
eye photoreceptor cell development GO:0042462 81 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
purine containing compound catabolic process GO:0072523 112 0.014
regulation of organelle organization GO:0033043 196 0.014
chemosensory behavior GO:0007635 106 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
regulation of gene expression epigenetic GO:0040029 128 0.013
sister chromatid cohesion GO:0007062 18 0.013
positive regulation of signal transduction GO:0009967 223 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of cell development GO:0060284 215 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
developmental pigmentation GO:0048066 68 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
lateral inhibition GO:0046331 206 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
sensory perception of salty taste GO:0050914 3 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
synapse assembly GO:0007416 143 0.013
secretion by cell GO:0032940 101 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
salivary gland histolysis GO:0035070 88 0.013
nucleoside catabolic process GO:0009164 112 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
oocyte differentiation GO:0009994 145 0.013
detection of external stimulus GO:0009581 66 0.013
xenobiotic catabolic process GO:0042178 1 0.013
actin cytoskeleton organization GO:0030036 206 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
regulation of synapse organization GO:0050807 110 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
response to organophosphorus GO:0046683 2 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
cellular protein localization GO:0034613 160 0.013
microtubule depolymerization GO:0007019 25 0.013
mating GO:0007618 120 0.013
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.013
response to radiation GO:0009314 155 0.013
regulation of multi organism process GO:0043900 131 0.013
mesenchymal cell differentiation GO:0048762 1 0.013
nephron epithelium development GO:0072009 3 0.013
rhythmic behavior GO:0007622 76 0.013
regulation of microtubule cytoskeleton organization GO:0070507 41 0.013
negative regulation of cell communication GO:0010648 223 0.013
mitotic nuclear division GO:0007067 213 0.012
sensory perception GO:0007600 196 0.012
mesenchymal cell development GO:0014031 1 0.012
epithelial cell development GO:0002064 274 0.012
digestive tract morphogenesis GO:0048546 127 0.012
detection of abiotic stimulus GO:0009582 66 0.012
actomyosin structure organization GO:0031032 56 0.012
central nervous system development GO:0007417 201 0.012
sensory organ morphogenesis GO:0090596 260 0.012
protein transport GO:0015031 155 0.012
epithelial cell differentiation GO:0030855 322 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
regulation of cellular localization GO:0060341 136 0.012
cholesterol homeostasis GO:0042632 3 0.012
organophosphate catabolic process GO:0046434 112 0.012
nephron morphogenesis GO:0072028 3 0.012
regulation of synapse assembly GO:0051963 94 0.012
learning or memory GO:0007611 141 0.012
embryonic axis specification GO:0000578 107 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
epiboly involved in wound healing GO:0090505 2 0.012
nephron epithelium morphogenesis GO:0072088 3 0.012
nucleotide catabolic process GO:0009166 109 0.012
cytoplasmic transport GO:0016482 130 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
cuticle development GO:0042335 86 0.012
wound healing spreading of epidermal cells GO:0035313 1 0.012
drinking behavior GO:0042756 2 0.012
chemical homeostasis GO:0048878 92 0.012
stem cell development GO:0048864 79 0.012
protein acylation GO:0043543 42 0.012
multi multicellular organism process GO:0044706 123 0.012
germ line stem cell maintenance GO:0030718 50 0.012
neuromuscular junction development GO:0007528 149 0.012
salt aversion GO:0035199 3 0.012
positive regulation of transport GO:0051050 92 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
sterol homeostasis GO:0055092 4 0.012
retina development in camera type eye GO:0060041 4 0.012
negative regulation of cell development GO:0010721 62 0.012
detection of light stimulus GO:0009583 58 0.012
negative regulation of organelle organization GO:0010639 56 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
response to alcohol GO:0097305 95 0.012
negative regulation of translation GO:0017148 28 0.012
regulation of apoptotic process GO:0042981 130 0.012
developmental maturation GO:0021700 172 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.011
regulation of cell proliferation GO:0042127 163 0.011
macromolecule catabolic process GO:0009057 161 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
apoptotic process involved in morphogenesis GO:0060561 3 0.011
dorsal closure GO:0007391 79 0.011
anion homeostasis GO:0055081 3 0.011
establishment of protein localization GO:0045184 163 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
macromolecular complex disassembly GO:0032984 37 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of molecular function GO:0065009 217 0.011
multi organism reproductive behavior GO:0044705 121 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
vitamin biosynthetic process GO:0009110 1 0.011
response to abiotic stimulus GO:0009628 341 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
fat soluble vitamin biosynthetic process GO:0042362 1 0.011
synaptic transmission GO:0007268 288 0.011
negative regulation of cell cycle GO:0045786 116 0.011
response to light stimulus GO:0009416 124 0.011
regulation of protein depolymerization GO:1901879 27 0.011
detection of stimulus involved in sensory perception GO:0050906 92 0.011
ion transport GO:0006811 145 0.011
cell recognition GO:0008037 102 0.011
dephosphorylation GO:0016311 51 0.011
memory GO:0007613 94 0.011
positive regulation of molecular function GO:0044093 136 0.011
digestive tract development GO:0048565 149 0.011
defense response to other organism GO:0098542 225 0.011
female meiotic division GO:0007143 70 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
lipid metabolic process GO:0006629 121 0.011
extracellular structure organization GO:0043062 46 0.011
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.011
fat soluble vitamin metabolic process GO:0006775 1 0.011
negative regulation of signal transduction GO:0009968 206 0.011
sensory perception of smell GO:0007608 80 0.011
epiboly GO:0090504 2 0.011
hormone catabolic process GO:0042447 3 0.010
microtubule based movement GO:0007018 51 0.010
epithelial cell migration open tracheal system GO:0007427 32 0.010
neuron recognition GO:0008038 101 0.010
tissue migration GO:0090130 155 0.010
rhythmic process GO:0048511 106 0.010
hindgut morphogenesis GO:0007442 58 0.010
acyl coa metabolic process GO:0006637 3 0.010
estrogen metabolic process GO:0008210 1 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
negative regulation of protein depolymerization GO:1901880 23 0.010
locomotory behavior GO:0007626 176 0.010
regulation of cellular component size GO:0032535 98 0.010
microtubule polymerization or depolymerization GO:0031109 39 0.010
cognition GO:0050890 141 0.010
positive regulation of lipid storage GO:0010884 4 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
cellular response to radiation GO:0071478 52 0.010
wnt signaling pathway GO:0016055 98 0.010
triglyceride biosynthetic process GO:0019432 2 0.010
sensory perception of pain GO:0019233 4 0.010
male courtship behavior GO:0008049 63 0.010
posttranscriptional gene silencing by rna GO:0035194 45 0.010
transmembrane transport GO:0055085 139 0.010
long term memory GO:0007616 62 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
morphogenesis of embryonic epithelium GO:0016331 94 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010

tomb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.023
sensory system disease DOID:0050155 0 0.015
disease of metabolism DOID:0014667 0 0.013
urinary system disease DOID:18 0 0.013
cardiovascular system disease DOID:1287 0 0.013
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
musculoskeletal system disease DOID:17 0 0.012
inherited metabolic disorder DOID:655 0 0.011
central nervous system disease DOID:331 0 0.011