Drosophila melanogaster

0 known processes

hubl (Dmel_CG30364)

hug-bell

(Aliases: anon-WO0140519.168,CG2149,CG30364,Dmel\CG30364)

hubl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.041
appendage development GO:0048736 401 0.037
imaginal disc derived appendage development GO:0048737 399 0.035
wing disc morphogenesis GO:0007472 344 0.033
response to external biotic stimulus GO:0043207 293 0.033
imaginal disc derived appendage morphogenesis GO:0035114 395 0.033
negative regulation of gene expression GO:0010629 387 0.031
catabolic process GO:0009056 409 0.031
cellular catabolic process GO:0044248 372 0.031
small molecule metabolic process GO:0044281 305 0.031
body morphogenesis GO:0010171 2 0.031
imaginal disc derived wing morphogenesis GO:0007476 337 0.031
post embryonic appendage morphogenesis GO:0035120 385 0.031
protein modification process GO:0036211 438 0.030
vesicle mediated transport GO:0016192 381 0.030
defense response GO:0006952 300 0.029
homeostatic process GO:0042592 199 0.029
oxoacid metabolic process GO:0043436 103 0.029
cellular protein modification process GO:0006464 438 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.028
response to abiotic stimulus GO:0009628 341 0.028
positive regulation of response to stimulus GO:0048584 323 0.027
response to other organism GO:0051707 293 0.027
negative regulation of cellular metabolic process GO:0031324 382 0.027
response to biotic stimulus GO:0009607 294 0.027
organic acid metabolic process GO:0006082 103 0.027
appendage morphogenesis GO:0035107 397 0.026
cell death GO:0008219 279 0.026
endocytosis GO:0006897 310 0.026
lateral inhibition GO:0046331 206 0.026
organic substance catabolic process GO:1901575 308 0.026
death GO:0016265 284 0.025
regionalization GO:0003002 416 0.025
nuclear division GO:0000280 332 0.025
single organism behavior GO:0044708 391 0.025
intracellular signal transduction GO:0035556 300 0.024
programmed cell death GO:0012501 257 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
immune system process GO:0002376 347 0.023
positive regulation of biosynthetic process GO:0009891 316 0.023
defense response to other organism GO:0098542 225 0.023
macromolecular complex assembly GO:0065003 256 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
phagocytosis GO:0006909 215 0.022
organic substance transport GO:0071702 257 0.022
gland development GO:0048732 191 0.022
positive regulation of cell communication GO:0010647 250 0.022
defense response to bacterium GO:0042742 178 0.022
organelle fission GO:0048285 340 0.022
compound eye development GO:0048749 307 0.022
cellular amino acid metabolic process GO:0006520 61 0.021
cholesterol homeostasis GO:0042632 3 0.021
protein complex biogenesis GO:0070271 201 0.021
regulation of anatomical structure size GO:0090066 163 0.021
response to organic substance GO:0010033 284 0.021
developmental growth GO:0048589 280 0.021
single organism catabolic process GO:0044712 228 0.021
eye development GO:0001654 323 0.021
regulation of cell cycle GO:0051726 291 0.021
positive regulation of signal transduction GO:0009967 223 0.020
compound eye morphogenesis GO:0001745 249 0.020
positive regulation of signaling GO:0023056 243 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
sterol homeostasis GO:0055092 4 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
single organism biosynthetic process GO:0044711 206 0.020
chaeta development GO:0022416 97 0.020
sensory organ morphogenesis GO:0090596 260 0.020
exocrine system development GO:0035272 162 0.020
protein localization GO:0008104 284 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.020
response to oxygen containing compound GO:1901700 200 0.020
negative regulation of response to stimulus GO:0048585 258 0.019
response to lipopolysaccharide GO:0032496 4 0.019
positive regulation of gene expression GO:0010628 290 0.019
phosphorylation GO:0016310 294 0.019
salivary gland development GO:0007431 162 0.019
open tracheal system development GO:0007424 204 0.019
growth GO:0040007 359 0.019
immune response GO:0006955 246 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
forebrain development GO:0030900 2 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
chromosome organization GO:0051276 360 0.019
establishment of localization in cell GO:0051649 402 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
locomotory behavior GO:0007626 176 0.019
regulation of immune system process GO:0002682 176 0.018
gland morphogenesis GO:0022612 145 0.018
cell proliferation GO:0008283 299 0.018
neurological system process GO:0050877 358 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
eye morphogenesis GO:0048592 260 0.018
developmental programmed cell death GO:0010623 138 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
salivary gland morphogenesis GO:0007435 145 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
regulation of protein metabolic process GO:0051246 256 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
regulation of response to stress GO:0080134 200 0.018
antimicrobial humoral response GO:0019730 99 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
response to bacterium GO:0009617 198 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
regulation of gene expression epigenetic GO:0040029 128 0.017
regulation of localization GO:0032879 275 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
regulation of molecular function GO:0065009 217 0.017
amine metabolic process GO:0009308 12 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
camera type eye development GO:0043010 4 0.017
macromolecule catabolic process GO:0009057 161 0.017
anion homeostasis GO:0055081 3 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
response to organophosphorus GO:0046683 2 0.017
heterocycle catabolic process GO:0046700 166 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
regulation of catalytic activity GO:0050790 185 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
cellular amine metabolic process GO:0044106 12 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
histolysis GO:0007559 102 0.016
respiratory system development GO:0060541 213 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
regulation of transport GO:0051049 181 0.016
gene silencing GO:0016458 138 0.016
segmentation GO:0035282 207 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
tissue morphogenesis GO:0048729 297 0.016
aromatic compound catabolic process GO:0019439 166 0.016
organophosphate metabolic process GO:0019637 195 0.016
tissue death GO:0016271 102 0.016
regulation of cell death GO:0010941 173 0.016
cell division GO:0051301 248 0.016
embryonic development via the syncytial blastoderm GO:0001700 148 0.016
adult behavior GO:0030534 137 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
mitotic spindle organization GO:0007052 220 0.016
ethanolamine containing compound metabolic process GO:0042439 4 0.016
defense response to gram negative bacterium GO:0050829 94 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
protein complex assembly GO:0006461 200 0.016
positive regulation of transcription dna templated GO:0045893 266 0.015
regulation of cell differentiation GO:0045595 302 0.015
xenobiotic catabolic process GO:0042178 1 0.015
epithelial cell development GO:0002064 274 0.015
proteolysis GO:0006508 192 0.015
ras protein signal transduction GO:0007265 88 0.015
humoral immune response GO:0006959 117 0.015
axis specification GO:0009798 167 0.015
endomembrane system organization GO:0010256 119 0.015
sensory perception of chemical stimulus GO:0007606 116 0.015
nucleotide metabolic process GO:0009117 161 0.015
spindle organization GO:0007051 253 0.015
intracellular transport GO:0046907 228 0.015
regulation of organelle organization GO:0033043 196 0.015
cellular macromolecule localization GO:0070727 220 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
telencephalon development GO:0021537 2 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
tube development GO:0035295 244 0.014
steroid catabolic process GO:0006706 1 0.014
cation transmembrane transport GO:0098655 88 0.014
mitotic nuclear division GO:0007067 213 0.014
epithelial cell differentiation GO:0030855 322 0.014
ion transport GO:0006811 145 0.014
multi organism behavior GO:0051705 175 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
detection of stimulus involved in sensory perception GO:0050906 92 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
salivary gland histolysis GO:0035070 88 0.014
meiotic cell cycle GO:0051321 171 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
developmental maturation GO:0021700 172 0.014
response to copper ion GO:0046688 4 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
negative regulation of gene expression epigenetic GO:0045814 77 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
salt aversion GO:0035199 3 0.014
epiboly involved in wound healing GO:0090505 2 0.014
regulation of cell cycle process GO:0010564 181 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
chromatin organization GO:0006325 207 0.013
vitamin metabolic process GO:0006766 2 0.013
cation transport GO:0006812 110 0.013
regulation of developmental growth GO:0048638 174 0.013
dna metabolic process GO:0006259 227 0.013
chromosome segregation GO:0007059 157 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
cell motility GO:0048870 251 0.013
response to radiation GO:0009314 155 0.013
single organism intracellular transport GO:1902582 207 0.013
taxis GO:0042330 304 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
cellular ketone metabolic process GO:0042180 24 0.013
positive regulation of lipid storage GO:0010884 4 0.013
anatomical structure homeostasis GO:0060249 97 0.013
response to temperature stimulus GO:0009266 106 0.013
monocarboxylic acid transport GO:0015718 3 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
response to monosaccharide GO:0034284 4 0.013
regulation of catabolic process GO:0009894 170 0.013
localization of cell GO:0051674 257 0.013
cell recognition GO:0008037 102 0.013
synaptic transmission GO:0007268 288 0.013
transmembrane transport GO:0055085 139 0.013
regulation of programmed cell death GO:0043067 152 0.013
autophagic cell death GO:0048102 83 0.013
establishment of protein localization GO:0045184 163 0.013
detection of stimulus GO:0051606 156 0.013
connective tissue development GO:0061448 3 0.013
muscle structure development GO:0061061 224 0.013
kidney development GO:0001822 3 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
metal ion transport GO:0030001 74 0.012
cholesterol transport GO:0030301 2 0.012
actin filament based process GO:0030029 220 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
negative regulation of developmental process GO:0051093 201 0.012
chemical homeostasis GO:0048878 92 0.012
neuron recognition GO:0008038 101 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
ion transmembrane transport GO:0034220 122 0.012
apoptotic process GO:0006915 159 0.012
response to hexose GO:0009746 3 0.012
triglyceride catabolic process GO:0019433 3 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
chemotaxis GO:0006935 249 0.012
negative regulation of cell communication GO:0010648 223 0.012
purine containing compound metabolic process GO:0072521 155 0.012
multicellular organismal reproductive behavior GO:0033057 110 0.012
regulation of multi organism process GO:0043900 131 0.012
sensory perception GO:0007600 196 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
negative regulation of signal transduction GO:0009968 206 0.012
axon development GO:0061564 297 0.012
aggressive behavior GO:0002118 63 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
regulation of lipid transport GO:0032368 3 0.012
regulation of immune response GO:0050776 118 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
negative regulation of signaling GO:0023057 219 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
sensory perception of pain GO:0019233 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
cell cycle phase transition GO:0044770 140 0.012
ovarian follicle cell development GO:0030707 248 0.012
tripartite regional subdivision GO:0007351 103 0.012
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.012
cellular protein localization GO:0034613 160 0.012
regulation of cell development GO:0060284 215 0.012
meiotic cell cycle process GO:1903046 132 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
regulation of defense response GO:0031347 102 0.012
regulation of growth GO:0040008 233 0.012
dendrite morphogenesis GO:0048813 199 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
androgen metabolic process GO:0008209 1 0.012
triglyceride biosynthetic process GO:0019432 2 0.012
embryonic pattern specification GO:0009880 174 0.012
protein phosphorylation GO:0006468 169 0.012
rna processing GO:0006396 147 0.011
cell migration GO:0016477 238 0.011
chromatin silencing GO:0006342 76 0.011
water homeostasis GO:0030104 3 0.011
axonogenesis GO:0007409 290 0.011
protein transport GO:0015031 155 0.011
male gamete generation GO:0048232 201 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
blastoderm segmentation GO:0007350 159 0.011
central nervous system development GO:0007417 201 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
actin cytoskeleton organization GO:0030036 206 0.011
regulation of hydrolase activity GO:0051336 97 0.011
cytoplasmic transport GO:0016482 130 0.011
peptidyl amino acid modification GO:0018193 105 0.011
response to nutrient levels GO:0031667 114 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
mrna metabolic process GO:0016071 124 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
benzene containing compound metabolic process GO:0042537 3 0.011
spermatogenesis GO:0007283 200 0.011
cellular amide metabolic process GO:0043603 80 0.011
larval behavior GO:0030537 42 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
acylglycerol catabolic process GO:0046464 3 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
organophosphate catabolic process GO:0046434 112 0.011
response to extracellular stimulus GO:0009991 116 0.011
response to alcohol GO:0097305 95 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
positive regulation of catabolic process GO:0009896 105 0.011
sensory perception of salty taste GO:0050914 3 0.011
drinking behavior GO:0042756 2 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
regulation of apoptotic process GO:0042981 130 0.011
hindbrain development GO:0030902 2 0.011
wound healing GO:0042060 75 0.011
protein heterooligomerization GO:0051291 4 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
innate immune response GO:0045087 144 0.011
regulation of cellular component size GO:0032535 98 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
positive regulation of molecular function GO:0044093 136 0.011
tube morphogenesis GO:0035239 191 0.011
membrane organization GO:0061024 112 0.011
cell adhesion GO:0007155 136 0.011
meiotic nuclear division GO:0007126 151 0.010
inorganic ion transmembrane transport GO:0098660 73 0.010
response to wounding GO:0009611 94 0.010
regulation of cell proliferation GO:0042127 163 0.010
single organism membrane organization GO:0044802 93 0.010
single organism cellular localization GO:1902580 180 0.010
response to endogenous stimulus GO:0009719 119 0.010
multicellular organismal aging GO:0010259 140 0.010
positive regulation of cell motility GO:2000147 3 0.010
carbohydrate metabolic process GO:0005975 82 0.010
embryonic morphogenesis GO:0048598 206 0.010
axon guidance GO:0007411 233 0.010
phosphatidylethanolamine metabolic process GO:0046337 1 0.010
inter male aggressive behavior GO:0002121 60 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
aging GO:0007568 143 0.010
synapse organization GO:0050808 196 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
response to starvation GO:0042594 97 0.010
response to organic cyclic compound GO:0014070 89 0.010
neuron projection guidance GO:0097485 241 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
protein maturation GO:0051604 71 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
fat soluble vitamin metabolic process GO:0006775 1 0.010
cellular response to organic substance GO:0071310 132 0.010
synapse assembly GO:0007416 143 0.010
acylglycerol biosynthetic process GO:0046463 2 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
immune response activating signal transduction GO:0002757 2 0.010
protein processing GO:0016485 68 0.010

hubl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.018
nervous system disease DOID:863 0 0.017
acquired metabolic disease DOID:0060158 0 0.016
cardiovascular system disease DOID:1287 0 0.012
diabetes mellitus DOID:9351 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
glucose metabolism disease DOID:4194 0 0.011
hypertension DOID:10763 0 0.010
artery disease DOID:0050828 0 0.010
vascular disease DOID:178 0 0.010
type 2 diabetes mellitus DOID:9352 0 0.010