Drosophila melanogaster

45 known processes

Pka-C3 (Dmel_CG6117)

cAMP-dependent protein kinase 3

(Aliases: Pk?5,Pk72A,PKA-C-3,Dmel\CG6117,PKA-C3,Dpck,CG6117,PKA C3,PKA,5-23,DC2)

Pka-C3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
morphogenesis of an epithelium GO:0002009 276 0.113
Human
wing disc morphogenesis GO:0007472 344 0.089
regulation of multicellular organismal development GO:2000026 414 0.085
Human Fly
appendage morphogenesis GO:0035107 397 0.083
regulation of cellular component biogenesis GO:0044087 201 0.082
Fly
single organism intracellular transport GO:1902582 207 0.078
imaginal disc derived appendage morphogenesis GO:0035114 395 0.070
single organism cellular localization GO:1902580 180 0.065
Fly
protein localization GO:0008104 284 0.063
appendage development GO:0048736 401 0.060
tissue morphogenesis GO:0048729 297 0.060
Human
regulation of localization GO:0032879 275 0.059
Human Fly
intracellular transport GO:0046907 228 0.058
regulation of developmental growth GO:0048638 174 0.056
regionalization GO:0003002 416 0.054
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.053
cell cell signaling involved in cell fate commitment GO:0045168 210 0.052
cell motility GO:0048870 251 0.052
Human
post embryonic appendage morphogenesis GO:0035120 385 0.051
embryonic development via the syncytial blastoderm GO:0001700 148 0.050
cellular protein localization GO:0034613 160 0.050
catabolic process GO:0009056 409 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.048
lateral inhibition GO:0046331 206 0.047
positive regulation of cellular biosynthetic process GO:0031328 316 0.047
embryo development ending in birth or egg hatching GO:0009792 152 0.046
epithelial cell differentiation GO:0030855 322 0.045
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.045
carboxylic acid metabolic process GO:0019752 92 0.045
developmental growth GO:0048589 280 0.043
body morphogenesis GO:0010171 2 0.042
negative regulation of response to stimulus GO:0048585 258 0.042
Fly
dorsal closure GO:0007391 79 0.041
positive regulation of gene expression GO:0010628 290 0.041
positive regulation of signaling GO:0023056 243 0.041
intracellular protein transport GO:0006886 104 0.040
detection of stimulus GO:0051606 156 0.040
regulation of microtubule based process GO:0032886 49 0.036
response to radiation GO:0009314 155 0.036
locomotory behavior GO:0007626 176 0.036
positive regulation of nucleic acid templated transcription GO:1903508 266 0.036
morphogenesis of embryonic epithelium GO:0016331 94 0.036
axon development GO:0061564 297 0.035
establishment of localization in cell GO:0051649 402 0.035
imaginal disc derived appendage development GO:0048737 399 0.035
organelle assembly GO:0070925 198 0.035
protein transport GO:0015031 155 0.034
phosphorylation GO:0016310 294 0.034
cell migration GO:0016477 238 0.034
Human
transmembrane transport GO:0055085 139 0.034
developmental pigmentation GO:0048066 68 0.033
chaeta development GO:0022416 97 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.032
sensory organ morphogenesis GO:0090596 260 0.031
regulation of cell differentiation GO:0045595 302 0.031
Human Fly
endocytosis GO:0006897 310 0.031
death GO:0016265 284 0.031
Fly
microtubule organizing center organization GO:0031023 168 0.031
cell projection assembly GO:0030031 94 0.031
positive regulation of cell communication GO:0010647 250 0.031
dendrite morphogenesis GO:0048813 199 0.031
establishment of protein localization GO:0045184 163 0.030
forebrain development GO:0030900 2 0.030
regulation of transport GO:0051049 181 0.030
detection of abiotic stimulus GO:0009582 66 0.030
response to organic substance GO:0010033 284 0.030
regulation of cell cycle GO:0051726 291 0.030
positive regulation of rna biosynthetic process GO:1902680 266 0.030
response to abiotic stimulus GO:0009628 341 0.029
Fly
cellular catabolic process GO:0044248 372 0.029
negative regulation of gene expression GO:0010629 387 0.029
regulation of epithelial cell differentiation GO:0030856 4 0.029
Human
organic substance catabolic process GO:1901575 308 0.029
cellular protein modification process GO:0006464 438 0.028
protein complex biogenesis GO:0070271 201 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.028
axon guidance GO:0007411 233 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.028
inorganic ion transmembrane transport GO:0098660 73 0.028
small molecule metabolic process GO:0044281 305 0.028
growth GO:0040007 359 0.028
Yeast
regulation of cytoskeleton organization GO:0051493 89 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
neuron projection guidance GO:0097485 241 0.027
regulation of cellular amine metabolic process GO:0033238 3 0.027
notch signaling pathway GO:0007219 120 0.027
centrosome organization GO:0051297 163 0.026
epidermal cell differentiation GO:0009913 51 0.026
organic acid metabolic process GO:0006082 103 0.026
male gamete generation GO:0048232 201 0.026
single organism biosynthetic process GO:0044711 206 0.025
cellular response to light stimulus GO:0071482 37 0.025
vesicle mediated transport GO:0016192 381 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
ribonucleotide metabolic process GO:0009259 145 0.025
nicotinamide nucleotide metabolic process GO:0046496 2 0.025
cellular macromolecule localization GO:0070727 220 0.024
Fly
positive regulation of protein complex assembly GO:0031334 22 0.024
vacuolar transport GO:0007034 13 0.024
response to light stimulus GO:0009416 124 0.024
taxis GO:0042330 304 0.024
localization of cell GO:0051674 257 0.024
Human
regulation of molecular function GO:0065009 217 0.024
Fly
regulation of embryonic development GO:0045995 68 0.024
Fly
positive regulation of rna metabolic process GO:0051254 271 0.023
regulation of growth GO:0040008 233 0.023
regulation of notch signaling pathway GO:0008593 100 0.023
photoreceptor cell differentiation GO:0046530 170 0.023
embryonic morphogenesis GO:0048598 206 0.023
oxoacid metabolic process GO:0043436 103 0.023
oxidoreduction coenzyme metabolic process GO:0006733 2 0.023
positive regulation of biosynthetic process GO:0009891 316 0.023
synapse organization GO:0050808 196 0.023
regulation of nervous system development GO:0051960 248 0.023
cation transport GO:0006812 110 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
neurological system process GO:0050877 358 0.023
Fly
cation transmembrane transport GO:0098655 88 0.023
nucleobase containing small molecule metabolic process GO:0055086 174 0.023
protein phosphorylation GO:0006468 169 0.023
macromolecular complex assembly GO:0065003 256 0.023
negative regulation of transcription dna templated GO:0045892 237 0.022
dendrite development GO:0016358 204 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.022
response to nutrient levels GO:0031667 114 0.022
cytoplasmic transport GO:0016482 130 0.022
chemotaxis GO:0006935 249 0.022
developmental maturation GO:0021700 172 0.022
Fly
negative regulation of developmental process GO:0051093 201 0.022
nucleotide metabolic process GO:0009117 161 0.022
spermatogenesis GO:0007283 200 0.022
synaptic transmission GO:0007268 288 0.022
Fly
cellular response to chemical stimulus GO:0070887 199 0.022
positive regulation of signal transduction GO:0009967 223 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
regulation of cellular localization GO:0060341 136 0.021
Fly
programmed cell death GO:0012501 257 0.021
Fly
telencephalon development GO:0021537 2 0.021
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.020
negative regulation of multicellular organismal process GO:0051241 142 0.020
imaginal disc pattern formation GO:0007447 91 0.020
Fly
ion transport GO:0006811 145 0.020
cell adhesion GO:0007155 136 0.020
Human Mouse
macromolecule catabolic process GO:0009057 161 0.020
regulation of organelle organization GO:0033043 196 0.020
regulation of microtubule cytoskeleton organization GO:0070507 41 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
skin development GO:0043588 65 0.019
autophagy GO:0006914 108 0.019
detection of chemical stimulus GO:0009593 93 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
regulation of cellular response to stress GO:0080135 89 0.019
regulation of protein metabolic process GO:0051246 256 0.019
negative regulation of growth GO:0045926 84 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
protein localization to organelle GO:0033365 82 0.018
protein complex assembly GO:0006461 200 0.018
protein modification process GO:0036211 438 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.018
amine metabolic process GO:0009308 12 0.018
cellular response to organic substance GO:0071310 132 0.018
hair cell differentiation GO:0035315 47 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
cellular response to extracellular stimulus GO:0031668 64 0.017
dorsal ventral pattern formation GO:0009953 133 0.017
regulation of cell development GO:0060284 215 0.017
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.017
negative regulation of rna metabolic process GO:0051253 251 0.017
segmentation GO:0035282 207 0.017
Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
salivary gland morphogenesis GO:0007435 145 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
cellular ketone metabolic process GO:0042180 24 0.017
negative regulation of nervous system development GO:0051961 92 0.017
chromosome organization GO:0051276 360 0.017
gland morphogenesis GO:0022612 145 0.017
response to organophosphorus GO:0046683 2 0.017
positive regulation of multicellular organismal process GO:0051240 143 0.017
respiratory system development GO:0060541 213 0.017
neuron recognition GO:0008038 101 0.017
actin filament based process GO:0030029 220 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
single organism behavior GO:0044708 391 0.017
Fly
axonogenesis GO:0007409 290 0.017
detection of stimulus involved in sensory perception GO:0050906 92 0.017
single organism catabolic process GO:0044712 228 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
peptidyl amino acid modification GO:0018193 105 0.016
Human
pigmentation GO:0043473 75 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
non sensory hair organization GO:0035316 47 0.016
cellular amine metabolic process GO:0044106 12 0.016
cell recognition GO:0008037 102 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
protein catabolic process GO:0030163 101 0.016
epithelial cell development GO:0002064 274 0.016
eye morphogenesis GO:0048592 260 0.016
homeostatic process GO:0042592 199 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
detection of light stimulus GO:0009583 58 0.016
nuclear division GO:0000280 332 0.016
organelle fission GO:0048285 340 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
mapk cascade GO:0000165 107 0.016
microtubule polymerization or depolymerization GO:0031109 39 0.016
regulation of protein localization GO:0032880 76 0.016
defense response GO:0006952 300 0.016
positive regulation of nervous system development GO:0051962 69 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
kidney development GO:0001822 3 0.016
Human
organonitrogen compound metabolic process GO:1901564 318 0.015
medium chain fatty acid metabolic process GO:0051791 1 0.015
organic substance transport GO:0071702 257 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
protein targeting GO:0006605 64 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
regulation of cell shape GO:0008360 113 0.015
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.015
anterior posterior axis specification GO:0009948 109 0.015
Fly
negative regulation of developmental growth GO:0048640 64 0.015
salivary gland development GO:0007431 162 0.015
inorganic cation transmembrane transport GO:0098662 61 0.015
secretion by cell GO:0032940 101 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
positive regulation of cellular component biogenesis GO:0044089 80 0.015
embryonic axis specification GO:0000578 107 0.015
Fly
ras protein signal transduction GO:0007265 88 0.015
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.015
regulation of catabolic process GO:0009894 170 0.015
dna metabolic process GO:0006259 227 0.015
monovalent inorganic cation transport GO:0015672 40 0.015
tissue death GO:0016271 102 0.015
response to other organism GO:0051707 293 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.015
regulation of protein polymerization GO:0032271 28 0.014
aromatic compound catabolic process GO:0019439 166 0.014
heterocycle catabolic process GO:0046700 166 0.014
detection of external stimulus GO:0009581 66 0.014
camera type eye development GO:0043010 4 0.014
connective tissue development GO:0061448 3 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
regulation of cell cycle process GO:0010564 181 0.014
compound eye morphogenesis GO:0001745 249 0.014
pyridine nucleotide metabolic process GO:0019362 2 0.014
regulation of neuron differentiation GO:0045664 103 0.014
exocrine system development GO:0035272 162 0.014
single organism membrane organization GO:0044802 93 0.014
sterol homeostasis GO:0055092 4 0.014
muscle organ development GO:0007517 127 0.014
limb morphogenesis GO:0035108 1 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
pigment metabolic process GO:0042440 84 0.013
positive regulation of developmental process GO:0051094 143 0.013
spermatid development GO:0007286 98 0.013
establishment of protein localization to organelle GO:0072594 62 0.013
response to biotic stimulus GO:0009607 294 0.013
response to lipopolysaccharide GO:0032496 4 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
organophosphate metabolic process GO:0019637 195 0.013
cellular response to nutrient levels GO:0031669 62 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.013
maintenance of location GO:0051235 73 0.013
cytoskeleton dependent intracellular transport GO:0030705 44 0.013
biological adhesion GO:0022610 138 0.013
Human Mouse
adult behavior GO:0030534 137 0.013
negative regulation of organelle organization GO:0010639 56 0.013
epithelium migration GO:0090132 148 0.013
Human
cellular response to external stimulus GO:0071496 66 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
negative regulation of signaling GO:0023057 219 0.013
Fly
chromatin organization GO:0006325 207 0.013
establishment of tissue polarity GO:0007164 87 0.013
negative regulation of cell communication GO:0010648 223 0.013
Fly
positive regulation of cell motility GO:2000147 3 0.013
protein complex disassembly GO:0043241 36 0.013
imaginal disc growth GO:0007446 37 0.013
jak stat cascade GO:0007259 49 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
regulation of phosphorylation GO:0042325 147 0.012
cyclic nucleotide metabolic process GO:0009187 28 0.012
regulation of catalytic activity GO:0050790 185 0.012
ameboidal type cell migration GO:0001667 151 0.012
Human
eye development GO:0001654 323 0.012
spindle organization GO:0007051 253 0.012
signal release GO:0023061 49 0.012
hindbrain development GO:0030902 2 0.012
rna processing GO:0006396 147 0.012
golgi organization GO:0007030 66 0.012
regulation of anatomical structure size GO:0090066 163 0.012
secretion GO:0046903 109 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
regulation of wnt signaling pathway GO:0030111 68 0.012
histolysis GO:0007559 102 0.012
phagocytosis GO:0006909 215 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
negative regulation of signal transduction GO:0009968 206 0.012
Fly
mesenchymal cell differentiation GO:0048762 1 0.012
cyclic nucleotide biosynthetic process GO:0009190 25 0.012
steroid catabolic process GO:0006706 1 0.012
neuromuscular junction development GO:0007528 149 0.012
camera type eye morphogenesis GO:0048593 2 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
cell cycle phase transition GO:0044770 140 0.012
regulation of vesicle mediated transport GO:0060627 59 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
synapse assembly GO:0007416 143 0.011
cell death GO:0008219 279 0.011
Fly
molting cycle GO:0042303 56 0.011
cell growth GO:0016049 108 0.011
chemical homeostasis GO:0048878 92 0.011
positive regulation of transport GO:0051050 92 0.011
protein import GO:0017038 55 0.011
regulation of neurogenesis GO:0050767 158 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
pigment biosynthetic process GO:0046148 36 0.011
regulation of intracellular transport GO:0032386 64 0.011
photoreceptor cell development GO:0042461 96 0.011
cellularization GO:0007349 90 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
wing disc pattern formation GO:0035222 66 0.011
morphogenesis of a polarized epithelium GO:0001738 93 0.011
aging GO:0007568 143 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
positive regulation of growth GO:0045927 75 0.011
cell proliferation GO:0008283 299 0.011
Human Mouse
developmental programmed cell death GO:0010623 138 0.011
metal ion transport GO:0030001 74 0.011
actin cytoskeleton organization GO:0030036 206 0.011
nucleoside catabolic process GO:0009164 112 0.011
limb development GO:0060173 1 0.011
peptidyl tyrosine phosphorylation GO:0018108 24 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
actin polymerization or depolymerization GO:0008154 31 0.011
regulation of response to stress GO:0080134 200 0.011
proteolysis GO:0006508 192 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
tissue migration GO:0090130 155 0.011
Human
central nervous system development GO:0007417 201 0.011
positive regulation of molecular function GO:0044093 136 0.011
Fly
salivary gland histolysis GO:0035070 88 0.011
eye pigment metabolic process GO:0042441 33 0.011
cell cycle arrest GO:0007050 4 0.011
cellular protein complex disassembly GO:0043624 35 0.011
protein processing GO:0016485 68 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
anatomical structure homeostasis GO:0060249 97 0.011
regulation of protein catabolic process GO:0042176 55 0.011
microtubule based transport GO:0010970 42 0.011
tube morphogenesis GO:0035239 191 0.010
Human
sensory perception of smell GO:0007608 80 0.010
autophagic cell death GO:0048102 83 0.010
microtubule bundle formation GO:0001578 27 0.010
salivary gland cell autophagic cell death GO:0035071 83 0.010
cell fate determination GO:0001709 91 0.010
response to trehalose GO:0010353 3 0.010
response to extracellular stimulus GO:0009991 116 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
epidermis development GO:0008544 65 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
gland development GO:0048732 191 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
response to endogenous stimulus GO:0009719 119 0.010
cell junction organization GO:0034330 57 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
endomembrane system organization GO:0010256 119 0.010
eye pigment biosynthetic process GO:0006726 32 0.010

Pka-C3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
cardiovascular system disease DOID:1287 0 0.030
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
nervous system disease DOID:863 0 0.013
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.011
artery disease DOID:0050828 0 0.011
vascular disease DOID:178 0 0.011
musculoskeletal system disease DOID:17 0 0.011