Drosophila melanogaster

0 known processes

Eno (Dmel_CG17654)

Enolase

(Aliases: BEST:LD15491,ENOA,CT32526,Dmel\CG17654,eno,anon-WO0153538.76,Eno2,CG17654,T18)

Eno biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 103 0.896
nad metabolic process GO:0019674 1 0.885
pyridine containing compound metabolic process GO:0072524 3 0.817
spermatid development GO:0007286 98 0.727
intracellular transport GO:0046907 228 0.690
glycolytic process GO:0006096 6 0.678
generation of precursor metabolites and energy GO:0006091 42 0.661
organonitrogen compound biosynthetic process GO:1901566 117 0.629
small molecule metabolic process GO:0044281 305 0.612
pyruvate metabolic process GO:0006090 7 0.590
spermatogenesis GO:0007283 200 0.560
pyridine nucleotide metabolic process GO:0019362 2 0.518
cellular respiration GO:0045333 26 0.485
organonitrogen compound metabolic process GO:1901564 318 0.484
nicotinamide nucleotide metabolic process GO:0046496 2 0.482
single organism biosynthetic process GO:0044711 206 0.454
carbohydrate catabolic process GO:0016052 7 0.451
nadh metabolic process GO:0006734 1 0.441
oxoacid metabolic process GO:0043436 103 0.415
oxidation reduction process GO:0055114 123 0.413
tricarboxylic acid metabolic process GO:0072350 1 0.375
catabolic process GO:0009056 409 0.374
single organism intracellular transport GO:1902582 207 0.355
organic substance catabolic process GO:1901575 308 0.348
single organism catabolic process GO:0044712 228 0.346
multicellular organismal aging GO:0010259 140 0.337
ribonucleoside biosynthetic process GO:0042455 3 0.332
establishment of localization in cell GO:0051649 402 0.330
energy derivation by oxidation of organic compounds GO:0015980 32 0.328
atp biosynthetic process GO:0006754 2 0.324
single organism carbohydrate catabolic process GO:0044724 7 0.311
atp metabolic process GO:0046034 49 0.299
aging GO:0007568 143 0.297
cytoplasmic microtubule organization GO:0031122 22 0.274
ribose phosphate metabolic process GO:0019693 145 0.266
determination of adult lifespan GO:0008340 137 0.266
carbohydrate biosynthetic process GO:0016051 17 0.261
regulation of imaginal disc derived wing size GO:0044719 20 0.247
carboxylic acid metabolic process GO:0019752 92 0.244
carbohydrate metabolic process GO:0005975 82 0.235
inorganic cation transmembrane transport GO:0098662 61 0.234
monocarboxylic acid metabolic process GO:0032787 29 0.230
nucleobase containing small molecule metabolic process GO:0055086 174 0.225
single organism carbohydrate metabolic process GO:0044723 72 0.217
cellular macromolecular complex assembly GO:0034622 153 0.210
acyl coa metabolic process GO:0006637 3 0.198
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.192
nucleotide metabolic process GO:0009117 161 0.183
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.183
negative regulation of cell cycle GO:0045786 116 0.179
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.179
cell proliferation GO:0008283 299 0.168
negative regulation of biosynthetic process GO:0009890 277 0.152
nucleoside metabolic process GO:0009116 127 0.150
spermatid differentiation GO:0048515 114 0.148
striated muscle myosin thick filament assembly GO:0071688 3 0.146
cellular response to chemical stimulus GO:0070887 199 0.141
endosomal transport GO:0016197 44 0.140
negative regulation of gene expression GO:0010629 387 0.139
male gamete generation GO:0048232 201 0.138
response to metal ion GO:0010038 23 0.131
organophosphate metabolic process GO:0019637 195 0.131
purine nucleoside monophosphate metabolic process GO:0009126 50 0.130
ribose phosphate biosynthetic process GO:0046390 28 0.130
muscle cell differentiation GO:0042692 103 0.124
negative regulation of cellular biosynthetic process GO:0031327 277 0.124
purine ribonucleotide metabolic process GO:0009150 145 0.122
purine nucleoside metabolic process GO:0042278 127 0.118
larval midgut histolysis GO:0035069 22 0.118
chaeta development GO:0022416 97 0.116
glutamate metabolic process GO:0006536 5 0.113
nucleoside monophosphate metabolic process GO:0009123 52 0.111
oxidoreduction coenzyme metabolic process GO:0006733 2 0.105
regulation of cell development GO:0060284 215 0.102
lipid localization GO:0010876 54 0.100
purine nucleoside triphosphate metabolic process GO:0009144 119 0.099
negative regulation of transcription dna templated GO:0045892 237 0.099
purine ribonucleoside metabolic process GO:0046128 127 0.097
larval development GO:0002164 104 0.097
organonitrogen compound catabolic process GO:1901565 128 0.096
regulation of cell differentiation GO:0045595 302 0.095
purine ribonucleotide biosynthetic process GO:0009152 28 0.090
pupal development GO:0035209 11 0.090
response to abiotic stimulus GO:0009628 341 0.088
regulation of cell proliferation GO:0042127 163 0.088
nucleoside phosphate metabolic process GO:0006753 162 0.086
syncytium formation GO:0006949 43 0.085
response to gravity GO:0009629 26 0.084
cellular modified amino acid metabolic process GO:0006575 45 0.084
proteolysis GO:0006508 192 0.084
chromatin silencing GO:0006342 76 0.082
organelle assembly GO:0070925 198 0.082
cellular protein complex assembly GO:0043623 71 0.082
negative regulation of gene expression epigenetic GO:0045814 77 0.081
negative regulation of response to stimulus GO:0048585 258 0.081
myofibril assembly GO:0030239 36 0.081
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.080
purine nucleoside biosynthetic process GO:0042451 3 0.078
respiratory electron transport chain GO:0022904 11 0.077
negative regulation of translation GO:0017148 28 0.076
rna localization GO:0006403 115 0.074
regulation of organ morphogenesis GO:2000027 78 0.073
posttranscriptional regulation of gene expression GO:0010608 145 0.072
neurotransmitter receptor metabolic process GO:0045213 3 0.070
cytoplasmic transport GO:0016482 130 0.069
homeostatic process GO:0042592 199 0.068
protein complex biogenesis GO:0070271 201 0.067
purine nucleotide metabolic process GO:0006163 146 0.067
ribonucleoside triphosphate metabolic process GO:0009199 119 0.066
centrosome cycle GO:0007098 137 0.066
myoblast fusion GO:0007520 43 0.062
negative regulation of cellular metabolic process GO:0031324 382 0.060
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.060
purine ribonucleoside biosynthetic process GO:0046129 3 0.059
imaginal disc derived wing morphogenesis GO:0007476 337 0.059
actin cytoskeleton organization GO:0030036 206 0.058
cell aging GO:0007569 2 0.056
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.056
organic substance transport GO:0071702 257 0.056
somatic muscle development GO:0007525 66 0.056
vesicle mediated transport GO:0016192 381 0.055
negative regulation of nucleic acid templated transcription GO:1903507 240 0.055
negative regulation of rna biosynthetic process GO:1902679 240 0.054
immune response GO:0006955 246 0.054
carbohydrate derivative metabolic process GO:1901135 217 0.052
phagocytosis GO:0006909 215 0.051
response to organic cyclic compound GO:0014070 89 0.051
carbohydrate derivative biosynthetic process GO:1901137 85 0.050
nucleoside triphosphate metabolic process GO:0009141 120 0.049
response to inorganic substance GO:0010035 44 0.048
ribonucleoside metabolic process GO:0009119 127 0.048
tube morphogenesis GO:0035239 191 0.048
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.047
glycosyl compound biosynthetic process GO:1901659 3 0.047
purine containing compound metabolic process GO:0072521 155 0.047
thioester metabolic process GO:0035383 3 0.046
response to organic substance GO:0010033 284 0.046
cellular amino acid metabolic process GO:0006520 61 0.045
cellular component assembly involved in morphogenesis GO:0010927 151 0.045
nucleotide biosynthetic process GO:0009165 34 0.045
protein localization GO:0008104 284 0.045
alpha amino acid biosynthetic process GO:1901607 4 0.045
maintenance of location GO:0051235 73 0.044
macromolecule catabolic process GO:0009057 161 0.044
cellular response to peptide GO:1901653 28 0.044
ribonucleoside monophosphate metabolic process GO:0009161 51 0.044
purine nucleotide catabolic process GO:0006195 109 0.044
embryo development ending in birth or egg hatching GO:0009792 152 0.043
cellular macromolecule localization GO:0070727 220 0.042
sulfur compound metabolic process GO:0006790 59 0.042
cellular response to hormone stimulus GO:0032870 44 0.042
ribonucleotide biosynthetic process GO:0009260 28 0.042
regulation of cell cycle GO:0051726 291 0.042
negative regulation of multicellular organismal process GO:0051241 142 0.039
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.038
growth GO:0040007 359 0.038
death GO:0016265 284 0.038
positive regulation of response to stimulus GO:0048584 323 0.038
nucleoside phosphate biosynthetic process GO:1901293 34 0.037
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.037
endocytosis GO:0006897 310 0.037
carboxylic acid biosynthetic process GO:0046394 15 0.037
negative regulation of cell differentiation GO:0045596 143 0.036
carboxylic acid catabolic process GO:0046395 16 0.036
macromolecular complex assembly GO:0065003 256 0.036
organic cyclic compound catabolic process GO:1901361 168 0.035
glutathione metabolic process GO:0006749 37 0.035
response to decreased oxygen levels GO:0036293 58 0.035
muscle structure development GO:0061061 224 0.035
small molecule biosynthetic process GO:0044283 37 0.035
tube development GO:0035295 244 0.035
purine nucleotide biosynthetic process GO:0006164 29 0.034
response to hypoxia GO:0001666 53 0.033
response to temperature stimulus GO:0009266 106 0.033
negative regulation of cell development GO:0010721 62 0.033
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.032
myosin filament organization GO:0031033 5 0.032
response to lithium ion GO:0010226 1 0.032
response to hexose GO:0009746 3 0.032
regulation of programmed cell death GO:0043067 152 0.032
cation transmembrane transport GO:0098655 88 0.031
positive regulation of proteolysis GO:0045862 52 0.031
striated muscle cell development GO:0055002 50 0.031
negative regulation of nervous system development GO:0051961 92 0.030
positive regulation of multicellular organismal process GO:0051240 143 0.030
aromatic compound catabolic process GO:0019439 166 0.030
actin filament based process GO:0030029 220 0.030
regulation of multicellular organismal development GO:2000026 414 0.030
heterocycle catabolic process GO:0046700 166 0.029
cellular metal ion homeostasis GO:0006875 31 0.029
gastrulation GO:0007369 70 0.029
cellular aldehyde metabolic process GO:0006081 10 0.029
inorganic ion transmembrane transport GO:0098660 73 0.029
response to oxygen levels GO:0070482 59 0.028
ion transport GO:0006811 145 0.028
head development GO:0060322 135 0.028
organophosphate biosynthetic process GO:0090407 46 0.028
positive regulation of cell communication GO:0010647 250 0.027
cellular amino acid biosynthetic process GO:0008652 9 0.027
cellular response to organic substance GO:0071310 132 0.027
ribonucleoside monophosphate catabolic process GO:0009158 39 0.027
regulation of apoptotic process GO:0042981 130 0.025
developmental programmed cell death GO:0010623 138 0.025
protein transport GO:0015031 155 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
citrate metabolic process GO:0006101 0 0.025
peptide metabolic process GO:0006518 80 0.025
response to nitrogen compound GO:1901698 90 0.025
carbohydrate derivative catabolic process GO:1901136 118 0.024
gene silencing GO:0016458 138 0.024
nucleoside biosynthetic process GO:0009163 3 0.024
protein complex assembly GO:0006461 200 0.024
cellular protein localization GO:0034613 160 0.024
negative regulation of signal transduction GO:0009968 206 0.024
regulation of translation GO:0006417 56 0.024
negative regulation of developmental process GO:0051093 201 0.023
response to organophosphorus GO:0046683 2 0.023
programmed cell death GO:0012501 257 0.023
membrane organization GO:0061024 112 0.023
ribonucleoside catabolic process GO:0042454 112 0.023
defense response GO:0006952 300 0.023
developmental growth GO:0048589 280 0.023
connective tissue development GO:0061448 3 0.023
apoptotic process GO:0006915 159 0.022
cytosolic calcium ion transport GO:0060401 2 0.022
cellular nitrogen compound catabolic process GO:0044270 165 0.022
negative regulation of epithelial cell proliferation GO:0050680 4 0.021
activation of cysteine type endopeptidase activity GO:0097202 17 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
biological adhesion GO:0022610 138 0.021
positive regulation of signaling GO:0023056 243 0.021
protein localization to nucleus GO:0034504 55 0.021
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.021
response to monosaccharide GO:0034284 4 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
negative regulation of cellular protein metabolic process GO:0032269 85 0.021
positive regulation of apoptotic process GO:0043065 47 0.021
androgen metabolic process GO:0008209 1 0.021
intracellular protein transport GO:0006886 104 0.021
regulation of localization GO:0032879 275 0.020
microtubule organizing center organization GO:0031023 168 0.020
nucleotide catabolic process GO:0009166 109 0.020
negative regulation of neurogenesis GO:0050768 53 0.020
negative regulation of cell communication GO:0010648 223 0.020
nucleoside monophosphate biosynthetic process GO:0009124 4 0.020
locomotory behavior GO:0007626 176 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
myosin filament assembly GO:0031034 5 0.019
dorsal ventral pattern formation GO:0009953 133 0.019
reproductive structure development GO:0048608 74 0.019
sex differentiation GO:0007548 81 0.019
regulation of nervous system development GO:0051960 248 0.019
immune system process GO:0002376 347 0.019
protein targeting GO:0006605 64 0.019
olfactory behavior GO:0042048 97 0.019
regulation of retinal cell programmed cell death GO:0046668 18 0.019
monocarboxylic acid biosynthetic process GO:0072330 7 0.018
cellular homeostasis GO:0019725 80 0.018
wing disc morphogenesis GO:0007472 344 0.018
cation homeostasis GO:0055080 51 0.018
kidney development GO:0001822 3 0.018
protein localization to organelle GO:0033365 82 0.018
cell maturation GO:0048469 144 0.018
synaptic transmission GO:0007268 288 0.018
nuclear transport GO:0051169 72 0.018
positive regulation of cell proliferation GO:0008284 47 0.018
organic acid biosynthetic process GO:0016053 15 0.018
cellular cation homeostasis GO:0030003 38 0.018
cell death GO:0008219 279 0.017
regeneration GO:0031099 16 0.017
intracellular signal transduction GO:0035556 300 0.017
centrosome organization GO:0051297 163 0.017
response to glucose GO:0009749 2 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
cellular response to decreased oxygen levels GO:0036294 30 0.017
actomyosin structure organization GO:0031032 56 0.017
negative regulation of cellular component organization GO:0051129 108 0.016
regulation of cell death GO:0010941 173 0.016
muscle cell development GO:0055001 50 0.016
organophosphate catabolic process GO:0046434 112 0.016
single organism cellular localization GO:1902580 180 0.016
monosaccharide metabolic process GO:0005996 9 0.016
maternal determination of anterior posterior axis embryo GO:0008358 74 0.016
aerobic respiration GO:0009060 11 0.016
gland development GO:0048732 191 0.016
glycosyl compound metabolic process GO:1901657 127 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
metal ion homeostasis GO:0055065 44 0.015
negative regulation of signaling GO:0023057 219 0.015
atp catabolic process GO:0006200 38 0.015
forebrain development GO:0030900 2 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
ion transmembrane transport GO:0034220 122 0.015
purine nucleoside monophosphate catabolic process GO:0009128 38 0.015
transmembrane transport GO:0055085 139 0.015
striated muscle cell differentiation GO:0051146 90 0.015
phosphorylation GO:0016310 294 0.015
mitochondrial transport GO:0006839 8 0.015
muscle system process GO:0003012 21 0.015
regulation of neuroblast proliferation GO:1902692 34 0.014
sensory perception GO:0007600 196 0.014
nucleoside catabolic process GO:0009164 112 0.014
centrosome duplication GO:0051298 121 0.014
nucleoside triphosphate biosynthetic process GO:0009142 2 0.014
development of primary sexual characteristics GO:0045137 50 0.014
g protein coupled receptor signaling pathway GO:0007186 136 0.014
innate immune response GO:0045087 144 0.014
response to biotic stimulus GO:0009607 294 0.014
negative regulation of neuroblast proliferation GO:0007406 27 0.014
digestive system development GO:0055123 149 0.014
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.014
chemotaxis GO:0006935 249 0.014
brain development GO:0007420 120 0.013
glutamine family amino acid catabolic process GO:0009065 3 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
regulation of membrane potential GO:0042391 35 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
small molecule catabolic process GO:0044282 21 0.013
purine containing compound catabolic process GO:0072523 112 0.013
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
response to endogenous stimulus GO:0009719 119 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
cellularization GO:0007349 90 0.013
protein targeting to nucleus GO:0044744 51 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
monovalent inorganic cation transport GO:0015672 40 0.012
atp synthesis coupled electron transport GO:0042773 8 0.012
response to nutrient levels GO:0031667 114 0.012
lipid metabolic process GO:0006629 121 0.012
establishment of protein localization to organelle GO:0072594 62 0.012
reproductive system development GO:0061458 74 0.012
synapse assembly GO:0007416 143 0.012
rna processing GO:0006396 147 0.012
cellular response to oxygen levels GO:0071453 30 0.012
response to lipid GO:0033993 38 0.012
response to external biotic stimulus GO:0043207 293 0.012
regulation of molecular function GO:0065009 217 0.012
gonad development GO:0008406 50 0.012
cofactor metabolic process GO:0051186 13 0.011
developmental pigmentation GO:0048066 68 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
negative regulation of stem cell proliferation GO:2000647 30 0.011
response to calcium ion GO:0051592 1 0.011
regulation of catalytic activity GO:0050790 185 0.011
establishment of protein localization GO:0045184 163 0.011
wing disc dorsal ventral pattern formation GO:0048190 47 0.011
positive regulation of developmental process GO:0051094 143 0.011
protein processing GO:0016485 68 0.011
digestive tract development GO:0048565 149 0.011
nucleoside monophosphate catabolic process GO:0009125 39 0.011
glucose metabolic process GO:0006006 5 0.011
positive regulation of growth GO:0045927 75 0.011
positive regulation of signal transduction GO:0009967 223 0.011
lipid storage GO:0019915 38 0.011
regulation of developmental growth GO:0048638 174 0.011
body morphogenesis GO:0010171 2 0.011
ocellus pigment metabolic process GO:0046158 19 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.010
regulation of neurogenesis GO:0050767 158 0.010
cellular amide metabolic process GO:0043603 80 0.010
calcium ion homeostasis GO:0055074 23 0.010
chromosome organization GO:0051276 360 0.010
digestive tract morphogenesis GO:0048546 127 0.010
estrogen metabolic process GO:0008210 1 0.010
regionalization GO:0003002 416 0.010
cell cycle arrest GO:0007050 4 0.010

Eno disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.177
disease of metabolism DOID:0014667 0 0.099
inherited metabolic disorder DOID:655 0 0.099
musculoskeletal system disease DOID:17 0 0.032
nervous system disease DOID:863 0 0.023
disease of cellular proliferation DOID:14566 0 0.022
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.014
muscular disease DOID:0080000 0 0.010