Drosophila melanogaster

61 known processes

frtz (Dmel_CG17657)

fritz

(Aliases: CG17657,Dmel\CG17657,anon-WO0118547.105)

frtz biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
morphogenesis of a polarized epithelium GO:0001738 93 0.906
imaginal disc derived wing hair organization GO:0035317 45 0.874
regulation of establishment of planar polarity GO:0090175 22 0.848
hair cell differentiation GO:0035315 47 0.755
establishment of tissue polarity GO:0007164 87 0.731
skin development GO:0043588 65 0.705
non sensory hair organization GO:0035316 47 0.664
establishment of planar polarity GO:0001736 87 0.616
actin cytoskeleton organization GO:0030036 206 0.610
establishment of monopolar cell polarity GO:0061162 15 0.446
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.434
regulation of organ morphogenesis GO:2000027 78 0.398
regulation of anatomical structure morphogenesis GO:0022603 242 0.368
proteolysis GO:0006508 192 0.329
negative regulation of cell communication GO:0010648 223 0.271
regulation of multicellular organismal development GO:2000026 414 0.240
negative regulation of response to stimulus GO:0048585 258 0.232
regulation of proteolysis GO:0030162 87 0.224
regulation of endopeptidase activity GO:0052548 36 0.206
negative regulation of gene expression GO:0010629 387 0.190
appendage morphogenesis GO:0035107 397 0.189
negative regulation of signal transduction GO:0009968 206 0.186
tissue morphogenesis GO:0048729 297 0.179
negative regulation of cellular metabolic process GO:0031324 382 0.159
wing disc morphogenesis GO:0007472 344 0.158
cellular macromolecule catabolic process GO:0044265 136 0.145
regulation of cellular protein metabolic process GO:0032268 243 0.139
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.138
imaginal disc derived appendage development GO:0048737 399 0.126
morphogenesis of an epithelium GO:0002009 276 0.126
negative regulation of notch signaling pathway GO:0045746 41 0.125
programmed cell death GO:0012501 257 0.123
modification dependent macromolecule catabolic process GO:0043632 79 0.123
epidermal cell differentiation GO:0009913 51 0.108
negative regulation of signaling GO:0023057 219 0.106
nephron development GO:0072006 3 0.106
appendage segmentation GO:0035285 26 0.106
vesicle mediated transport GO:0016192 381 0.102
positive regulation of cellular protein metabolic process GO:0032270 118 0.099
regulation of epithelial cell proliferation GO:0050678 4 0.096
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.093
determination of digestive tract left right asymmetry GO:0071907 6 0.091
positive regulation of macromolecule metabolic process GO:0010604 405 0.090
establishment or maintenance of cell polarity GO:0007163 167 0.086
cellular catabolic process GO:0044248 372 0.084
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.081
regulation of anatomical structure size GO:0090066 163 0.079
negative regulation of programmed cell death GO:0043069 72 0.076
regulation of cellular component biogenesis GO:0044087 201 0.073
regulation of cell morphogenesis GO:0022604 163 0.073
protein processing GO:0016485 68 0.070
cellular pigmentation GO:0033059 12 0.070
camera type eye morphogenesis GO:0048593 2 0.067
endocytosis GO:0006897 310 0.066
negative regulation of protein metabolic process GO:0051248 85 0.065
regulation of cysteine type endopeptidase activity GO:2000116 27 0.064
dendrite self avoidance GO:0070593 8 0.060
protein complex assembly GO:0006461 200 0.059
post embryonic appendage morphogenesis GO:0035120 385 0.059
positive regulation of proteolysis GO:0045862 52 0.059
striated muscle cell differentiation GO:0051146 90 0.059
regulation of peptidase activity GO:0052547 39 0.058
cell cell signaling involved in cell fate commitment GO:0045168 210 0.057
germarium derived egg chamber formation GO:0007293 101 0.053
heart development GO:0007507 82 0.053
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.052
death GO:0016265 284 0.051
skeletal muscle fiber development GO:0048741 3 0.051
negative regulation of cellular protein metabolic process GO:0032269 85 0.050
regulation of apoptotic process GO:0042981 130 0.049
phagocytosis GO:0006909 215 0.048
imaginal disc derived leg joint morphogenesis GO:0016348 15 0.048
vesicle organization GO:0016050 44 0.047
apoptotic process GO:0006915 159 0.045
wnt signaling pathway GO:0016055 98 0.044
positive regulation of cell migration GO:0030335 2 0.044
positive regulation of endopeptidase activity GO:0010950 26 0.044
compound eye development GO:0048749 307 0.043
establishment of epithelial cell apical basal polarity GO:0045198 10 0.042
cell death GO:0008219 279 0.042
regulation of tube size GO:0035150 46 0.042
protein modification by small protein conjugation GO:0032446 79 0.041
regulation of cell death GO:0010941 173 0.041
protein catabolic process GO:0030163 101 0.041
positive regulation of protein metabolic process GO:0051247 128 0.040
negative regulation of proteolysis GO:0045861 31 0.040
formation of anatomical boundary GO:0048859 37 0.040
appendage development GO:0048736 401 0.039
regionalization GO:0003002 416 0.039
negative regulation of protein processing GO:0010955 31 0.039
cell junction organization GO:0034330 57 0.039
imaginal disc derived wing hair site selection GO:0035320 4 0.038
biological adhesion GO:0022610 138 0.038
morphogenesis of a branching epithelium GO:0061138 45 0.038
chaeta morphogenesis GO:0008407 42 0.038
cell division GO:0051301 248 0.038
regulation of protein metabolic process GO:0051246 256 0.038
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.036
leg disc development GO:0035218 92 0.036
regulation of epithelial cell differentiation GO:0030856 4 0.034
synapse organization GO:0050808 196 0.034
skeletal muscle organ development GO:0060538 48 0.034
protein maturation GO:0051604 71 0.034
neural retina development GO:0003407 4 0.033
gland development GO:0048732 191 0.032
positive regulation of response to stimulus GO:0048584 323 0.032
establishment of ommatidial planar polarity GO:0042067 49 0.032
notch signaling pathway GO:0007219 120 0.031
regulation of programmed cell death GO:0043067 152 0.031
regulation of catalytic activity GO:0050790 185 0.031
intracellular signal transduction GO:0035556 300 0.031
imaginal disc derived appendage morphogenesis GO:0035114 395 0.031
endomembrane system organization GO:0010256 119 0.031
cellular protein catabolic process GO:0044257 83 0.031
positive regulation of cell cycle GO:0045787 43 0.031
negative regulation of wnt signaling pathway GO:0030178 28 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.030
eye photoreceptor cell differentiation GO:0001754 145 0.030
positive regulation of mitotic cell cycle GO:0045931 34 0.029
macromolecular complex assembly GO:0065003 256 0.029
regulation of mitotic cell cycle GO:0007346 190 0.029
regulation of cellular component size GO:0032535 98 0.029
neuromuscular junction development GO:0007528 149 0.029
kidney morphogenesis GO:0060993 3 0.029
positive regulation of catalytic activity GO:0043085 118 0.029
cellular protein modification process GO:0006464 438 0.028
ubiquitin dependent protein catabolic process GO:0006511 78 0.028
regulation of embryonic development GO:0045995 68 0.028
eye development GO:0001654 323 0.028
negative regulation of apoptotic process GO:0043066 63 0.028
kidney epithelium development GO:0072073 3 0.028
positive regulation of cell motility GO:2000147 3 0.027
imaginal disc derived leg segmentation GO:0036011 26 0.027
exocrine system development GO:0035272 162 0.027
neuron recognition GO:0008038 101 0.027
amine metabolic process GO:0009308 12 0.027
developmental growth involved in morphogenesis GO:0060560 65 0.026
protein modification process GO:0036211 438 0.026
cilium morphogenesis GO:0060271 39 0.026
regulation of cellular catabolic process GO:0031329 157 0.026
epidermis development GO:0008544 65 0.026
nephron tubule development GO:0072080 3 0.026
regulation of notch signaling pathway GO:0008593 100 0.025
mapk cascade GO:0000165 107 0.025
regulation of cell cycle GO:0051726 291 0.025
regulation of smoothened signaling pathway GO:0008589 28 0.025
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.025
response to bacterium GO:0009617 198 0.025
protein complex biogenesis GO:0070271 201 0.025
positive regulation of cellular component biogenesis GO:0044089 80 0.025
positive regulation of transcription dna templated GO:0045893 266 0.025
regulation of organelle organization GO:0033043 196 0.025
cell recognition GO:0008037 102 0.024
negative regulation of neuron death GO:1901215 18 0.024
eye morphogenesis GO:0048592 260 0.024
positive regulation of cellular catabolic process GO:0031331 95 0.024
hematopoietic progenitor cell differentiation GO:0002244 1 0.024
organic substance transport GO:0071702 257 0.024
organic substance catabolic process GO:1901575 308 0.024
establishment of body hair or bristle planar orientation GO:0048104 6 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.023
catabolic process GO:0009056 409 0.023
negative regulation of rna biosynthetic process GO:1902679 240 0.023
antennal morphogenesis GO:0048800 14 0.023
actin filament polymerization GO:0030041 27 0.023
salivary gland development GO:0007431 162 0.022
kidney development GO:0001822 3 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
regulation of protein processing GO:0070613 32 0.022
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.022
organelle assembly GO:0070925 198 0.022
cuticle pattern formation GO:0035017 27 0.022
cell cell junction organization GO:0045216 55 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
regulation of nervous system development GO:0051960 248 0.021
cellular component assembly involved in morphogenesis GO:0010927 151 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.021
determination of bilateral symmetry GO:0009855 13 0.021
photoreceptor cell differentiation GO:0046530 170 0.020
regulation of cell division GO:0051302 72 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
epithelial cell differentiation GO:0030855 322 0.020
muscle fiber development GO:0048747 12 0.020
regulation of cellular response to growth factor stimulus GO:0090287 13 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
cell adhesion GO:0007155 136 0.019
response to other organism GO:0051707 293 0.019
embryonic morphogenesis GO:0048598 206 0.019
growth GO:0040007 359 0.018
regulation of synapse organization GO:0050807 110 0.018
single organism carbohydrate metabolic process GO:0044723 72 0.018
malpighian tubule morphogenesis GO:0007443 44 0.018
membrane organization GO:0061024 112 0.018
sensory organ morphogenesis GO:0090596 260 0.018
regulation of neural precursor cell proliferation GO:2000177 35 0.018
regulation of imaginal disc derived wing size GO:0044719 20 0.018
regulation of neuron projection development GO:0010975 69 0.018
limb development GO:0060173 1 0.018
negative regulation of protein maturation GO:1903318 31 0.018
response to wounding GO:0009611 94 0.017
camera type eye development GO:0043010 4 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
negative regulation of neuron apoptotic process GO:0043524 14 0.017
eye pigment granule organization GO:0008057 12 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
regulation of actin cytoskeleton organization GO:0032956 42 0.017
spinal cord development GO:0021510 1 0.017
regulation of mitotic cell cycle phase transition GO:1901990 130 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
pigmentation GO:0043473 75 0.017
developmental pigmentation GO:0048066 68 0.017
protein phosphorylation GO:0006468 169 0.017
synaptic growth at neuromuscular junction GO:0051124 119 0.017
neurological system process GO:0050877 358 0.017
mucopolysaccharide metabolic process GO:1903510 5 0.016
inositol lipid mediated signaling GO:0048017 4 0.016
regulation of response to stress GO:0080134 200 0.016
lateral inhibition GO:0046331 206 0.016
central nervous system development GO:0007417 201 0.016
positive regulation of transferase activity GO:0051347 26 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
retina development in camera type eye GO:0060041 4 0.016
hindbrain development GO:0030902 2 0.016
gonad development GO:0008406 50 0.016
axon extension GO:0048675 32 0.016
wound healing GO:0042060 75 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
gland morphogenesis GO:0022612 145 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
positive regulation of lipid metabolic process GO:0045834 4 0.015
stress activated mapk cascade GO:0051403 52 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
regulation of protein complex assembly GO:0043254 42 0.015
non canonical wnt signaling pathway GO:0035567 8 0.015
developmental cell growth GO:0048588 52 0.015
cell growth GO:0016049 108 0.015
muscle structure development GO:0061061 224 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
ameboidal type cell migration GO:0001667 151 0.015
positive regulation of cellular component organization GO:0051130 156 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
cuticle pigmentation GO:0048067 22 0.014
defense response GO:0006952 300 0.014
regulation of hydrolase activity GO:0051336 97 0.014
regulation of tube size open tracheal system GO:0035151 43 0.014
salivary gland morphogenesis GO:0007435 145 0.014
actin filament organization GO:0007015 126 0.014
developmental growth GO:0048589 280 0.014
positive regulation of signal transduction GO:0009967 223 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
regulation of tube architecture open tracheal system GO:0035152 68 0.014
stem cell proliferation GO:0072089 88 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
muscle cell differentiation GO:0042692 103 0.014
regulation of stress activated mapk cascade GO:0032872 41 0.014
macromolecule catabolic process GO:0009057 161 0.013
establishment of apical basal cell polarity GO:0035089 12 0.013
branching involved in open tracheal system development GO:0060446 45 0.013
regulation of cell development GO:0060284 215 0.013
regulation of cellular response to stress GO:0080135 89 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
nucleus localization GO:0051647 34 0.013
response to organophosphorus GO:0046683 2 0.013
endosomal transport GO:0016197 44 0.013
positive regulation of protein modification process GO:0031401 58 0.013
regulation of cell shape GO:0008360 113 0.013
retinal ganglion cell axon guidance GO:0031290 12 0.013
regulation of cell size GO:0008361 63 0.013
tube formation GO:0035148 21 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
regulation of phosphorylation GO:0042325 147 0.012
actin polymerization or depolymerization GO:0008154 31 0.012
positive regulation of kinase activity GO:0033674 25 0.012
imaginal disc derived leg morphogenesis GO:0007480 80 0.012
convergent extension involved in gastrulation GO:0060027 2 0.012
oxoacid metabolic process GO:0043436 103 0.012
positive regulation of protein kinase activity GO:0045860 25 0.012
negative regulation of peptidase activity GO:0010466 11 0.012
positive regulation of protein complex assembly GO:0031334 22 0.012
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.012
body morphogenesis GO:0010171 2 0.012
protein ubiquitination GO:0016567 70 0.012
regulation of mitosis GO:0007088 56 0.012
regulation of cell cycle process GO:0010564 181 0.012
protein transport GO:0015031 155 0.012
activation of protein kinase activity GO:0032147 12 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
equator specification GO:0045317 4 0.011
retina morphogenesis in camera type eye GO:0060042 2 0.011
lamellipodium organization GO:0097581 21 0.011
positive regulation of molecular function GO:0044093 136 0.011
jnk cascade GO:0007254 50 0.011
organelle localization GO:0051640 148 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
response to biotic stimulus GO:0009607 294 0.011
regulation of wound healing GO:0061041 13 0.011
regulation of endocytosis GO:0030100 37 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
regulation of map kinase activity GO:0043405 17 0.011
regulation of tube length open tracheal system GO:0035159 24 0.011
pigment granule organization GO:0048753 12 0.011
negative regulation of cell fate specification GO:0009996 15 0.011
protein localization to organelle GO:0033365 82 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
positive regulation of gene expression GO:0010628 290 0.010
positive regulation of cell cycle process GO:0090068 28 0.010
polarized epithelial cell differentiation GO:0030859 10 0.010
positive regulation of phosphorylation GO:0042327 87 0.010

frtz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.046
central nervous system disease DOID:331 0 0.015