Drosophila melanogaster

31 known processes

Fpps (Dmel_CG12389)

Farnesyl pyrophosphate synthase

(Aliases: Dmel\CG12389,l(2)k06103,fps,DmFPPS,fpps,FPS,CG12389,v(2)k03514)

Fpps biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.376
ribonucleoside catabolic process GO:0042454 112 0.355
ribonucleoside metabolic process GO:0009119 127 0.256
germ cell migration GO:0008354 43 0.187
organonitrogen compound metabolic process GO:1901564 318 0.185
purine ribonucleoside metabolic process GO:0046128 127 0.183
purine ribonucleoside catabolic process GO:0046130 112 0.177
glycosyl compound metabolic process GO:1901657 127 0.166
ribonucleoside triphosphate catabolic process GO:0009203 108 0.154
nucleoside metabolic process GO:0009116 127 0.143
purine nucleotide catabolic process GO:0006195 109 0.142
organophosphate metabolic process GO:0019637 195 0.141
negative regulation of rna biosynthetic process GO:1902679 240 0.134
negative regulation of gene expression GO:0010629 387 0.127
peptide metabolic process GO:0006518 80 0.126
nucleoside catabolic process GO:0009164 112 0.123
purine nucleoside metabolic process GO:0042278 127 0.122
protein modification process GO:0036211 438 0.115
glycosyl compound catabolic process GO:1901658 112 0.115
purine nucleoside catabolic process GO:0006152 112 0.114
nucleotide metabolic process GO:0009117 161 0.112
negative regulation of cellular biosynthetic process GO:0031327 277 0.112
purine containing compound metabolic process GO:0072521 155 0.111
nucleobase containing small molecule metabolic process GO:0055086 174 0.110
cellularization GO:0007349 90 0.110
response to abiotic stimulus GO:0009628 341 0.105
purine ribonucleotide metabolic process GO:0009150 145 0.102
regionalization GO:0003002 416 0.099
nucleoside phosphate metabolic process GO:0006753 162 0.097
catabolic process GO:0009056 409 0.092
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.091
transcription from rna polymerase ii promoter GO:0006366 368 0.090
purine nucleotide metabolic process GO:0006163 146 0.088
purine ribonucleotide catabolic process GO:0009154 109 0.087
carbohydrate derivative metabolic process GO:1901135 217 0.087
organic substance catabolic process GO:1901575 308 0.085
epithelial cell differentiation GO:0030855 322 0.084
mrna processing GO:0006397 104 0.083
ribonucleotide metabolic process GO:0009259 145 0.083
nucleoside triphosphate metabolic process GO:0009141 120 0.083
purine nucleoside triphosphate catabolic process GO:0009146 108 0.082
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.080
response to nutrient levels GO:0031667 114 0.073
purine containing compound catabolic process GO:0072523 112 0.071
neuron projection guidance GO:0097485 241 0.071
microtubule organizing center organization GO:0031023 168 0.070
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.065
organophosphate catabolic process GO:0046434 112 0.062
sulfur compound metabolic process GO:0006790 59 0.061
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.060
mushroom body development GO:0016319 70 0.060
cellular protein modification process GO:0006464 438 0.059
establishment of localization in cell GO:0051649 402 0.058
ethanolamine containing compound metabolic process GO:0042439 4 0.058
cellular amino acid metabolic process GO:0006520 61 0.056
regulation of protein metabolic process GO:0051246 256 0.056
nucleotide catabolic process GO:0009166 109 0.056
negative regulation of transcription dna templated GO:0045892 237 0.056
ribonucleoside triphosphate metabolic process GO:0009199 119 0.056
nucleoside phosphate catabolic process GO:1901292 110 0.055
negative regulation of protein metabolic process GO:0051248 85 0.055
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.055
ribose phosphate metabolic process GO:0019693 145 0.054
nucleoside triphosphate catabolic process GO:0009143 108 0.053
negative regulation of rna metabolic process GO:0051253 251 0.053
negative regulation of cellular metabolic process GO:0031324 382 0.052
ribonucleotide catabolic process GO:0009261 109 0.051
cellular nitrogen compound catabolic process GO:0044270 165 0.051
aromatic compound catabolic process GO:0019439 166 0.050
response to extracellular stimulus GO:0009991 116 0.049
organonitrogen compound catabolic process GO:1901565 128 0.049
regulation of molecular function GO:0065009 217 0.049
purine nucleoside triphosphate metabolic process GO:0009144 119 0.048
response to radiation GO:0009314 155 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.047
oxoacid metabolic process GO:0043436 103 0.046
positive regulation of macromolecule metabolic process GO:0010604 405 0.044
negative regulation of cell cycle GO:0045786 116 0.044
cell death GO:0008219 279 0.044
central nervous system development GO:0007417 201 0.043
positive regulation of biosynthetic process GO:0009891 316 0.043
regulation of cellular ketone metabolic process GO:0010565 3 0.043
rna localization GO:0006403 115 0.043
death GO:0016265 284 0.042
cell motility GO:0048870 251 0.042
regulation of phosphate metabolic process GO:0019220 210 0.042
cell maturation GO:0048469 144 0.042
oocyte axis specification GO:0007309 108 0.042
rna splicing via transesterification reactions GO:0000375 73 0.042
single organism catabolic process GO:0044712 228 0.042
carboxylic acid metabolic process GO:0019752 92 0.041
organelle assembly GO:0070925 198 0.041
telencephalon development GO:0021537 2 0.040
positive regulation of cellular component biogenesis GO:0044089 80 0.040
carbohydrate derivative catabolic process GO:1901136 118 0.040
oocyte anterior posterior axis specification GO:0007314 72 0.040
regulation of multi organism process GO:0043900 131 0.039
guanosine containing compound metabolic process GO:1901068 74 0.038
phenol containing compound metabolic process GO:0018958 57 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.038
cytokinesis GO:0000910 90 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.036
regulation of catabolic process GO:0009894 170 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.035
guanosine containing compound catabolic process GO:1901069 74 0.035
carbohydrate metabolic process GO:0005975 82 0.035
oocyte construction GO:0007308 112 0.035
brain development GO:0007420 120 0.035
programmed cell death GO:0012501 257 0.035
negative regulation of biosynthetic process GO:0009890 277 0.034
cation transport GO:0006812 110 0.034
cellular catabolic process GO:0044248 372 0.034
protein import GO:0017038 55 0.034
positive regulation of phosphate metabolic process GO:0045937 139 0.034
organonitrogen compound biosynthetic process GO:1901566 117 0.034
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.034
organic acid metabolic process GO:0006082 103 0.033
pole cell formation GO:0007279 19 0.033
apoptotic process GO:0006915 159 0.033
negative regulation of nucleic acid templated transcription GO:1903507 240 0.033
cellular amide metabolic process GO:0043603 80 0.032
growth GO:0040007 359 0.032
cullin deneddylation GO:0010388 3 0.032
organic hydroxy compound metabolic process GO:1901615 83 0.032
purine nucleoside monophosphate metabolic process GO:0009126 50 0.031
intracellular protein transport GO:0006886 104 0.030
melanization defense response GO:0035006 45 0.030
chaeta development GO:0022416 97 0.029
positive regulation of cellular catabolic process GO:0031331 95 0.028
axis specification GO:0009798 167 0.028
atp metabolic process GO:0046034 49 0.028
rna splicing GO:0008380 83 0.027
multicellular organism growth GO:0035264 46 0.027
response to ionizing radiation GO:0010212 32 0.027
localization of cell GO:0051674 257 0.027
regulation of cell cycle process GO:0010564 181 0.027
defense response to other organism GO:0098542 225 0.027
gtp catabolic process GO:0006184 72 0.027
regulation of catalytic activity GO:0050790 185 0.027
leg disc morphogenesis GO:0007478 80 0.027
pole cell development GO:0007277 26 0.027
positive regulation of cell communication GO:0010647 250 0.027
regulation of cellular catabolic process GO:0031329 157 0.026
segmentation GO:0035282 207 0.026
ribonucleoside monophosphate catabolic process GO:0009158 39 0.026
nitrogen compound transport GO:0071705 85 0.026
organic cyclic compound catabolic process GO:1901361 168 0.026
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.025
cellular component assembly involved in morphogenesis GO:0010927 151 0.024
positive regulation of transport GO:0051050 92 0.024
intracellular signal transduction GO:0035556 300 0.024
forebrain development GO:0030900 2 0.024
dorsal ventral pattern formation GO:0009953 133 0.024
nucleobase containing compound catabolic process GO:0034655 165 0.024
single organism intracellular transport GO:1902582 207 0.023
response to heat GO:0009408 63 0.023
ribonucleoside monophosphate metabolic process GO:0009161 51 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
positive regulation of cell death GO:0010942 69 0.023
nucleoside monophosphate catabolic process GO:0009125 39 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
columnar cuboidal epithelial cell development GO:0002066 249 0.022
gtp metabolic process GO:0046039 72 0.022
cytoskeleton dependent cytokinesis GO:0061640 81 0.022
positive regulation of signal transduction GO:0009967 223 0.022
larval development GO:0002164 104 0.022
Worm
embryo development ending in birth or egg hatching GO:0009792 152 0.021
Worm
embryonic pattern specification GO:0009880 174 0.021
cellular macromolecular complex assembly GO:0034622 153 0.021
intracellular transport GO:0046907 228 0.021
regulation of protein complex disassembly GO:0043244 29 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
antimicrobial peptide production GO:0002775 46 0.021
heterocycle catabolic process GO:0046700 166 0.021
regulation of mrna metabolic process GO:1903311 72 0.020
response to other organism GO:0051707 293 0.020
oocyte differentiation GO:0009994 145 0.020
cellular protein complex disassembly GO:0043624 35 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
posttranscriptional gene silencing by rna GO:0035194 45 0.020
maintenance of location GO:0051235 73 0.020
regulation of cell death GO:0010941 173 0.020
negative regulation of cellular protein metabolic process GO:0032269 85 0.020
protein deneddylation GO:0000338 8 0.020
regulation of localization GO:0032879 275 0.019
ras protein signal transduction GO:0007265 88 0.019
establishment of protein localization GO:0045184 163 0.019
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.019
positive regulation of exocytosis GO:0045921 4 0.019
hemocyte differentiation GO:0042386 38 0.018
kidney morphogenesis GO:0060993 3 0.018
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.018
eggshell formation GO:0030703 105 0.018
pole plasm assembly GO:0007315 61 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
axon development GO:0061564 297 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
chemotaxis GO:0006935 249 0.018
oocyte microtubule cytoskeleton organization GO:0016325 35 0.018
nucleoside monophosphate metabolic process GO:0009123 52 0.018
regulation of cellular amide metabolic process GO:0034248 39 0.018
g protein coupled receptor signaling pathway GO:0007186 136 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
organic substance transport GO:0071702 257 0.017
immune system process GO:0002376 347 0.017
protein localization GO:0008104 284 0.017
imaginal disc pattern formation GO:0007447 91 0.017
axon guidance GO:0007411 233 0.017
mitochondrion organization GO:0007005 65 0.017
developmental maturation GO:0021700 172 0.017
secretion GO:0046903 109 0.017
negative regulation of cytoskeleton organization GO:0051494 30 0.017
body morphogenesis GO:0010171 2 0.017
positive regulation of multicellular organismal process GO:0051240 143 0.017
macromolecular complex assembly GO:0065003 256 0.017
response to temperature stimulus GO:0009266 106 0.017
imaginal disc derived leg morphogenesis GO:0007480 80 0.016
molting cycle chitin based cuticle GO:0007591 56 0.016
defense response to bacterium GO:0042742 178 0.016
regulation of pole plasm oskar mrna localization GO:0007317 27 0.016
response to organic substance GO:0010033 284 0.016
cellular modified amino acid metabolic process GO:0006575 45 0.016
response to biotic stimulus GO:0009607 294 0.016
pole plasm oskar mrna localization GO:0045451 46 0.016
innate immune response GO:0045087 144 0.016
mitotic dna integrity checkpoint GO:0044774 75 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
cellular macromolecule localization GO:0070727 220 0.016
regulation of hydrolase activity GO:0051336 97 0.015
hematopoietic progenitor cell differentiation GO:0002244 1 0.015
muscle system process GO:0003012 21 0.015
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.015
regulation of neurotransmitter levels GO:0001505 38 0.015
spermatogenesis GO:0007283 200 0.015
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.015
regulation of synapse structure and activity GO:0050803 128 0.015
muscle organ development GO:0007517 127 0.015
single organism biosynthetic process GO:0044711 206 0.015
cellular component disassembly GO:0022411 46 0.015
detection of stimulus GO:0051606 156 0.015
positive regulation of developmental growth GO:0048639 62 0.015
protein targeting GO:0006605 64 0.014
oocyte development GO:0048599 124 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
protein complex biogenesis GO:0070271 201 0.014
ion transport GO:0006811 145 0.014
microtubule polymerization or depolymerization GO:0031109 39 0.014
tube morphogenesis GO:0035239 191 0.014
spliceosomal snrnp assembly GO:0000387 2 0.014
protein phosphorylation GO:0006468 169 0.014
determination of adult lifespan GO:0008340 137 0.014
positive regulation of signaling GO:0023056 243 0.014
endomembrane system organization GO:0010256 119 0.014
peptide biosynthetic process GO:0043043 42 0.014
nuclear import GO:0051170 51 0.014
cytoplasmic transport GO:0016482 130 0.014
positive regulation of gene expression GO:0010628 290 0.014
regulation of cell division GO:0051302 72 0.014
regulation of transport GO:0051049 181 0.014
response to external biotic stimulus GO:0043207 293 0.014
membrane organization GO:0061024 112 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
rna processing GO:0006396 147 0.013
negative regulation of cell death GO:0060548 81 0.013
inorganic cation transmembrane transport GO:0098662 61 0.013
establishment of rna localization GO:0051236 47 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
regulation of nuclear division GO:0051783 58 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.013
negative regulation of developmental process GO:0051093 201 0.013
pole plasm protein localization GO:0007318 10 0.013
chitin based cuticle sclerotization GO:0007593 19 0.013
positive regulation of synapse assembly GO:0051965 29 0.013
developmental growth GO:0048589 280 0.013
regulation of ion transport GO:0043269 39 0.013
atp catabolic process GO:0006200 38 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.013
post embryonic appendage morphogenesis GO:0035120 385 0.013
multicellular organismal aging GO:0010259 140 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.013
regulation of intracellular protein transport GO:0033157 46 0.013
negative regulation of phosphorus metabolic process GO:0010563 45 0.013
peptidyl amino acid modification GO:0018193 105 0.012
cellular response to organic substance GO:0071310 132 0.012
protein modification by small protein removal GO:0070646 28 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
proteolysis GO:0006508 192 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
regulation of nucleotide metabolic process GO:0006140 62 0.012
protein transport GO:0015031 155 0.012
regulation of autophagy GO:0010506 62 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.012
protein import into nucleus GO:0006606 51 0.012
regulation of mrna 3 end processing GO:0031440 7 0.012
melanin metabolic process GO:0006582 47 0.012
nephron morphogenesis GO:0072028 3 0.012
male gamete generation GO:0048232 201 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
retina development in camera type eye GO:0060041 4 0.012
mrna metabolic process GO:0016071 124 0.012
negative regulation of molecular function GO:0044092 51 0.011
blastoderm segmentation GO:0007350 159 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
regulation of developmental growth GO:0048638 174 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
cell migration GO:0016477 238 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
molting cycle GO:0042303 56 0.011
striated muscle cell development GO:0055002 50 0.011
ovarian follicle cell development GO:0030707 248 0.011
cation transmembrane transport GO:0098655 88 0.011
nucleobase containing compound transport GO:0015931 56 0.011
oocyte maturation GO:0001556 3 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
positive regulation of catabolic process GO:0009896 105 0.011
rna interference GO:0016246 27 0.011
phagocytosis GO:0006909 215 0.011
pteridine metabolic process GO:0019889 5 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
wing disc morphogenesis GO:0007472 344 0.010
regulation of antimicrobial peptide production GO:0002784 44 0.010
dorsal ventral axis specification GO:0009950 66 0.010
regulation of phosphorus metabolic process GO:0051174 210 0.010
taxis GO:0042330 304 0.010
response to dsrna GO:0043331 15 0.010
regulation of protein modification process GO:0031399 112 0.010
regulation of response to biotic stimulus GO:0002831 63 0.010
single organism nuclear import GO:1902593 51 0.010
connective tissue development GO:0061448 3 0.010
regulation of dna templated transcription elongation GO:0032784 17 0.010
epithelial cell development GO:0002064 274 0.010
hindbrain development GO:0030902 2 0.010
sex differentiation GO:0007548 81 0.010
centriole replication GO:0007099 24 0.010
amide biosynthetic process GO:0043604 42 0.010
regulation of programmed cell death GO:0043067 152 0.010
regulation of synapse organization GO:0050807 110 0.010
phosphorylation GO:0016310 294 0.010
regulation of protein complex assembly GO:0043254 42 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010

Fpps disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.024
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
central nervous system disease DOID:331 0 0.018
neurodegenerative disease DOID:1289 0 0.018
motor neuron disease DOID:231 0 0.015
cardiovascular system disease DOID:1287 0 0.012
organ system cancer DOID:0050686 0 0.010