Drosophila melanogaster

15 known processes

CG42588 (Dmel_CG42588)

CG42588 gene product from transcript CG42588-RA

(Aliases: CG32108,Dmel_CG32108,BP1016,BcDNA:SD20456,CG34017,Dmel_CG11008,Dmel_CG34017,Dmel\CG42588,CG11008)

CG42588 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular biosynthetic process GO:0031328 316 0.103
chromosome organization GO:0051276 360 0.095
cellular catabolic process GO:0044248 372 0.086
establishment of localization in cell GO:0051649 402 0.080
regulation of multicellular organismal development GO:2000026 414 0.079
chromatin organization GO:0006325 207 0.072
catabolic process GO:0009056 409 0.070
organic substance catabolic process GO:1901575 308 0.068
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.068
vesicle mediated transport GO:0016192 381 0.067
positive regulation of macromolecule metabolic process GO:0010604 405 0.067
imaginal disc derived appendage development GO:0048737 399 0.065
positive regulation of biosynthetic process GO:0009891 316 0.064
response to organic substance GO:0010033 284 0.064
triglyceride biosynthetic process GO:0019432 2 0.060
gene silencing GO:0016458 138 0.056
organelle fission GO:0048285 340 0.056
regulation of cell differentiation GO:0045595 302 0.055
dna conformation change GO:0071103 105 0.054
positive regulation of gene expression GO:0010628 290 0.053
imaginal disc derived appendage morphogenesis GO:0035114 395 0.052
meiotic cell cycle GO:0051321 171 0.051
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.051
positive regulation of rna metabolic process GO:0051254 271 0.050
negative regulation of gene expression GO:0010629 387 0.049
wing disc morphogenesis GO:0007472 344 0.049
heterocycle catabolic process GO:0046700 166 0.048
single organism biosynthetic process GO:0044711 206 0.048
negative regulation of nucleic acid templated transcription GO:1903507 240 0.048
macromolecular complex assembly GO:0065003 256 0.047
neurological system process GO:0050877 358 0.047
transcription from rna polymerase ii promoter GO:0006366 368 0.046
response to abiotic stimulus GO:0009628 341 0.045
appendage morphogenesis GO:0035107 397 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.044
homeostatic process GO:0042592 199 0.043
aromatic compound catabolic process GO:0019439 166 0.043
regulation of protein metabolic process GO:0051246 256 0.042
cellular response to dna damage stimulus GO:0006974 223 0.041
imaginal disc derived wing morphogenesis GO:0007476 337 0.041
acylglycerol catabolic process GO:0046464 3 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.039
small molecule metabolic process GO:0044281 305 0.038
negative regulation of biosynthetic process GO:0009890 277 0.038
appendage development GO:0048736 401 0.038
negative regulation of cellular metabolic process GO:0031324 382 0.038
protein localization GO:0008104 284 0.036
regulation of localization GO:0032879 275 0.036
positive regulation of rna biosynthetic process GO:1902680 266 0.036
mitotic cell cycle phase transition GO:0044772 138 0.036
organonitrogen compound metabolic process GO:1901564 318 0.036
cellular nitrogen compound catabolic process GO:0044270 165 0.036
cell proliferation GO:0008283 299 0.036
cellular macromolecular complex assembly GO:0034622 153 0.035
positive regulation of nucleic acid templated transcription GO:1903508 266 0.035
organonitrogen compound catabolic process GO:1901565 128 0.035
dna packaging GO:0006323 91 0.035
regulation of nervous system development GO:0051960 248 0.035
protein modification process GO:0036211 438 0.035
regulation of cell development GO:0060284 215 0.034
cholesterol homeostasis GO:0042632 3 0.034
endocytosis GO:0006897 310 0.034
taxis GO:0042330 304 0.033
gland development GO:0048732 191 0.033
response to nitrogen compound GO:1901698 90 0.033
regionalization GO:0003002 416 0.033
cellular macromolecule localization GO:0070727 220 0.032
regulation of mitotic cell cycle GO:0007346 190 0.032
proteolysis GO:0006508 192 0.032
positive regulation of cellular catabolic process GO:0031331 95 0.031
chromatin modification GO:0016568 147 0.031
regulation of cellular catabolic process GO:0031329 157 0.031
intracellular transport GO:0046907 228 0.031
negative regulation of developmental process GO:0051093 201 0.030
response to temperature stimulus GO:0009266 106 0.030
organic substance transport GO:0071702 257 0.030
protein complex assembly GO:0006461 200 0.030
death GO:0016265 284 0.030
phagocytosis GO:0006909 215 0.029
regulation of gene expression epigenetic GO:0040029 128 0.029
single organism intracellular transport GO:1902582 207 0.029
positive regulation of cellular protein metabolic process GO:0032270 118 0.029
histone modification GO:0016570 106 0.029
cell death GO:0008219 279 0.028
mrna processing GO:0006397 104 0.028
regulation of phosphorus metabolic process GO:0051174 210 0.028
regulation of catabolic process GO:0009894 170 0.028
regulation of cell cycle phase transition GO:1901987 130 0.028
regulation of mitotic cell cycle phase transition GO:1901990 130 0.028
rna processing GO:0006396 147 0.028
cytoplasmic transport GO:0016482 130 0.027
post embryonic appendage morphogenesis GO:0035120 385 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
nuclear division GO:0000280 332 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
positive regulation of transcription dna templated GO:0045893 266 0.027
dna metabolic process GO:0006259 227 0.026
organelle assembly GO:0070925 198 0.026
response to oxygen containing compound GO:1901700 200 0.026
central nervous system development GO:0007417 201 0.026
spindle organization GO:0007051 253 0.026
positive regulation of cell communication GO:0010647 250 0.026
positive regulation of protein metabolic process GO:0051247 128 0.026
negative regulation of gene expression epigenetic GO:0045814 77 0.026
organic cyclic compound catabolic process GO:1901361 168 0.026
regulation of cell cycle GO:0051726 291 0.025
regulation of response to stress GO:0080134 200 0.025
negative regulation of nervous system development GO:0051961 92 0.025
positive regulation of signaling GO:0023056 243 0.025
cellular response to chemical stimulus GO:0070887 199 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
nucleobase containing compound catabolic process GO:0034655 165 0.024
regulation of proteolysis GO:0030162 87 0.024
meiotic cell cycle process GO:1903046 132 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.024
glycerolipid catabolic process GO:0046503 3 0.024
rhythmic process GO:0048511 106 0.024
negative regulation of multicellular organismal process GO:0051241 142 0.024
dna repair GO:0006281 54 0.024
mitotic dna integrity checkpoint GO:0044774 75 0.024
protein complex biogenesis GO:0070271 201 0.024
single organism catabolic process GO:0044712 228 0.024
developmental growth GO:0048589 280 0.024
organophosphate metabolic process GO:0019637 195 0.023
developmental maturation GO:0021700 172 0.023
negative regulation of transcription dna templated GO:0045892 237 0.023
chemical homeostasis GO:0048878 92 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
mitotic nuclear division GO:0007067 213 0.023
growth GO:0040007 359 0.023
axon development GO:0061564 297 0.023
protein targeting to nucleus GO:0044744 51 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
negative regulation of signaling GO:0023057 219 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.023
protein transport GO:0015031 155 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
glycosyl compound catabolic process GO:1901658 112 0.022
phosphorylation GO:0016310 294 0.022
regulation of cell death GO:0010941 173 0.022
establishment of protein localization GO:0045184 163 0.022
response to external biotic stimulus GO:0043207 293 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
neutral lipid catabolic process GO:0046461 3 0.022
chromatin remodeling GO:0006338 72 0.021
single organism behavior GO:0044708 391 0.021
nucleocytoplasmic transport GO:0006913 72 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
cellular macromolecule catabolic process GO:0044265 136 0.021
locomotory behavior GO:0007626 176 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
purine nucleotide metabolic process GO:0006163 146 0.021
posttranscriptional gene silencing by rna GO:0035194 45 0.021
oxoacid metabolic process GO:0043436 103 0.021
intracellular signal transduction GO:0035556 300 0.021
regulation of organelle organization GO:0033043 196 0.021
cellular response to organic substance GO:0071310 132 0.021
regulation of cell cycle process GO:0010564 181 0.020
organic acid metabolic process GO:0006082 103 0.020
macromolecule catabolic process GO:0009057 161 0.020
ras protein signal transduction GO:0007265 88 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
mrna metabolic process GO:0016071 124 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
axonogenesis GO:0007409 290 0.020
response to other organism GO:0051707 293 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.020
positive regulation of catabolic process GO:0009896 105 0.020
amine metabolic process GO:0009308 12 0.020
cation transmembrane transport GO:0098655 88 0.020
cellular protein modification process GO:0006464 438 0.020
programmed cell death GO:0012501 257 0.020
nucleoside triphosphate metabolic process GO:0009141 120 0.020
response to organonitrogen compound GO:0010243 75 0.020
response to endogenous stimulus GO:0009719 119 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
posttranscriptional gene silencing GO:0016441 46 0.019
secretion by cell GO:0032940 101 0.019
nucleotide metabolic process GO:0009117 161 0.019
cell fate determination GO:0001709 91 0.019
small gtpase mediated signal transduction GO:0007264 88 0.019
posttranscriptional regulation of gene expression GO:0010608 145 0.019
single organism cellular localization GO:1902580 180 0.019
organophosphate catabolic process GO:0046434 112 0.019
response to radiation GO:0009314 155 0.019
forebrain development GO:0030900 2 0.019
nucleotide catabolic process GO:0009166 109 0.019
triglyceride catabolic process GO:0019433 3 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
axon guidance GO:0007411 233 0.018
nucleoside metabolic process GO:0009116 127 0.018
ribonucleotide metabolic process GO:0009259 145 0.018
cation transport GO:0006812 110 0.018
ion transport GO:0006811 145 0.018
learning or memory GO:0007611 141 0.018
chemosensory behavior GO:0007635 106 0.018
acylglycerol biosynthetic process GO:0046463 2 0.018
segmentation GO:0035282 207 0.018
purine nucleotide catabolic process GO:0006195 109 0.018
response to decreased oxygen levels GO:0036293 58 0.018
negative regulation of cell communication GO:0010648 223 0.018
response to organic cyclic compound GO:0014070 89 0.018
sterol homeostasis GO:0055092 4 0.018
axis specification GO:0009798 167 0.018
mitotic cell cycle checkpoint GO:0007093 88 0.018
regulation of cellular localization GO:0060341 136 0.018
regulation of transport GO:0051049 181 0.018
cellular homeostasis GO:0019725 80 0.018
regulation of cell proliferation GO:0042127 163 0.018
circadian behavior GO:0048512 76 0.018
blastoderm segmentation GO:0007350 159 0.017
spermatogenesis GO:0007283 200 0.017
mitotic dna damage checkpoint GO:0044773 74 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
glycosyl compound metabolic process GO:1901657 127 0.017
embryonic pattern specification GO:0009880 174 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
establishment or maintenance of cell polarity GO:0007163 167 0.017
intracellular protein transport GO:0006886 104 0.017
meiosis i GO:0007127 59 0.017
transmembrane transport GO:0055085 139 0.017
cell cycle phase transition GO:0044770 140 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
chromosome condensation GO:0030261 41 0.017
cellular amine metabolic process GO:0044106 12 0.017
telencephalon development GO:0021537 2 0.017
salivary gland development GO:0007431 162 0.017
regulation of neurogenesis GO:0050767 158 0.017
antimicrobial humoral response GO:0019730 99 0.017
response to organophosphorus GO:0046683 2 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
regulation of molecular function GO:0065009 217 0.016
positive regulation of developmental process GO:0051094 143 0.016
regulation of sequestering of triglyceride GO:0010889 3 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
dna integrity checkpoint GO:0031570 81 0.016
regulation of immune system process GO:0002682 176 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
nuclear transport GO:0051169 72 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
cognition GO:0050890 141 0.016
response to monosaccharide GO:0034284 4 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
negative regulation of cell development GO:0010721 62 0.016
purine containing compound catabolic process GO:0072523 112 0.016
regulation of programmed cell death GO:0043067 152 0.016
cell maturation GO:0048469 144 0.015
response to bacterium GO:0009617 198 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
lipid metabolic process GO:0006629 121 0.015
cell cycle checkpoint GO:0000075 95 0.015
protein maturation GO:0051604 71 0.015
oocyte development GO:0048599 124 0.015
response to lipopolysaccharide GO:0032496 4 0.015
meiotic nuclear division GO:0007126 151 0.015
nucleoside catabolic process GO:0009164 112 0.015
olfactory learning GO:0008355 56 0.015
regulation of catalytic activity GO:0050790 185 0.015
response to hexose GO:0009746 3 0.015
immune system process GO:0002376 347 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
regulation of mrna metabolic process GO:1903311 72 0.015
dorsal ventral pattern formation GO:0009953 133 0.014
chromatin assembly or disassembly GO:0006333 52 0.014
inorganic ion transmembrane transport GO:0098660 73 0.014
positive regulation of signal transduction GO:0009967 223 0.014
neuron projection guidance GO:0097485 241 0.014
compound eye development GO:0048749 307 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
establishment of protein localization to organelle GO:0072594 62 0.014
nuclear import GO:0051170 51 0.014
synapse organization GO:0050808 196 0.014
defense response to other organism GO:0098542 225 0.014
purine containing compound metabolic process GO:0072521 155 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
defense response GO:0006952 300 0.014
rhythmic behavior GO:0007622 76 0.014
regulation of response to external stimulus GO:0032101 115 0.014
phenol containing compound metabolic process GO:0018958 57 0.014
gene silencing by rna GO:0031047 57 0.014
response to hypoxia GO:0001666 53 0.014
protein targeting GO:0006605 64 0.014
biological adhesion GO:0022610 138 0.014
maintenance of location GO:0051235 73 0.014
tissue death GO:0016271 102 0.014
pigmentation GO:0043473 75 0.014
mitotic spindle organization GO:0007052 220 0.014
response to glucose GO:0009749 2 0.014
translation GO:0006412 69 0.014
chromosome segregation GO:0007059 157 0.014
muscle organ development GO:0007517 127 0.014
epithelial cell development GO:0002064 274 0.014
photoreceptor cell development GO:0042461 96 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
protein dna complex subunit organization GO:0071824 86 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
negative regulation of neurogenesis GO:0050768 53 0.013
regulation of multi organism process GO:0043900 131 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
negative regulation of signal transduction GO:0009968 206 0.013
chemotaxis GO:0006935 249 0.013
dna damage checkpoint GO:0000077 78 0.013
organic hydroxy compound metabolic process GO:1901615 83 0.013
cellular protein localization GO:0034613 160 0.013
cell motility GO:0048870 251 0.013
regulation of growth GO:0040008 233 0.013
anatomical structure homeostasis GO:0060249 97 0.013
rna localization GO:0006403 115 0.013
alternative mrna splicing via spliceosome GO:0000380 60 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
regulation of hydrolase activity GO:0051336 97 0.013
immune response GO:0006955 246 0.012
cellular amide metabolic process GO:0043603 80 0.012
signal release GO:0023061 49 0.012
mitotic sister chromatid segregation GO:0000070 87 0.012
regulation of immune response GO:0050776 118 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
rna splicing via transesterification reactions GO:0000375 73 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
protein localization to organelle GO:0033365 82 0.012
mapk cascade GO:0000165 107 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
synaptic transmission GO:0007268 288 0.012
positive regulation of lipid metabolic process GO:0045834 4 0.012
protein import into nucleus GO:0006606 51 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
eye development GO:0001654 323 0.012
molting cycle GO:0042303 56 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
compound eye morphogenesis GO:0001745 249 0.012
memory GO:0007613 94 0.012
ion homeostasis GO:0050801 55 0.012
regulation of gtpase activity GO:0043087 44 0.012
regulation of neuron differentiation GO:0045664 103 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
kidney development GO:0001822 3 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
tissue morphogenesis GO:0048729 297 0.012
regulation of gene silencing GO:0060968 63 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
body morphogenesis GO:0010171 2 0.012
mating GO:0007618 120 0.012
salivary gland histolysis GO:0035070 88 0.012
regulation of translation GO:0006417 56 0.012
response to oxygen levels GO:0070482 59 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
anterior posterior axis specification GO:0009948 109 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
regulation of phosphorylation GO:0042325 147 0.011
positive regulation of transport GO:0051050 92 0.011
tripartite regional subdivision GO:0007351 103 0.011
neuronal stem cell division GO:0036445 35 0.011
actin filament based process GO:0030029 220 0.011
spindle elongation GO:0051231 83 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
stem cell differentiation GO:0048863 117 0.011
male gamete generation GO:0048232 201 0.011
exocrine system development GO:0035272 162 0.011
rna splicing GO:0008380 83 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
pigment metabolic process GO:0042440 84 0.011
zymogen activation GO:0031638 20 0.011
circadian rhythm GO:0007623 105 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of cellular response to stress GO:0080135 89 0.011
compound eye photoreceptor development GO:0042051 78 0.011
apoptotic process GO:0006915 159 0.011
gliogenesis GO:0042063 80 0.011
defense response to bacterium GO:0042742 178 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
connective tissue development GO:0061448 3 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
regulation of synaptic transmission GO:0050804 69 0.011
multi organism behavior GO:0051705 175 0.011
protein processing GO:0016485 68 0.011
lipid localization GO:0010876 54 0.011
cellular lipid metabolic process GO:0044255 83 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
regulation of production of molecular mediator of immune response GO:0002700 44 0.011
oocyte construction GO:0007308 112 0.010
positive regulation of molecular function GO:0044093 136 0.010
adult behavior GO:0030534 137 0.010
regulation of mrna processing GO:0050684 71 0.010
chromatin silencing GO:0006342 76 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.010
sensory perception of chemical stimulus GO:0007606 116 0.010
protein localization to nucleus GO:0034504 55 0.010
regulation of protein modification process GO:0031399 112 0.010
negative regulation of cell cycle phase transition GO:1901988 103 0.010
eye photoreceptor cell development GO:0042462 81 0.010
monovalent inorganic cation transport GO:0015672 40 0.010
protein catabolic process GO:0030163 101 0.010
regulation of developmental growth GO:0048638 174 0.010
single organism nuclear import GO:1902593 51 0.010
neural precursor cell proliferation GO:0061351 75 0.010
sister chromatid segregation GO:0000819 92 0.010
ameboidal type cell migration GO:0001667 151 0.010
regulation of cell division GO:0051302 72 0.010
protein dna complex assembly GO:0065004 63 0.010

CG42588 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.079
nervous system disease DOID:863 0 0.025
disease of metabolism DOID:0014667 0 0.019
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
inherited metabolic disorder DOID:655 0 0.014
musculoskeletal system disease DOID:17 0 0.013
central nervous system disease DOID:331 0 0.013
neurodegenerative disease DOID:1289 0 0.013