Drosophila melanogaster

48 known processes

nito (Dmel_CG2910)

spenito

(Aliases: cg2910,Dmel\CG2910,Dm44A/spenito,dOTT,BcDNA:GH11110,CG2910,DmSSp)

nito biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 0.509
regulation of anatomical structure morphogenesis GO:0022603 242 0.351
compound eye development GO:0048749 307 0.316
compound eye morphogenesis GO:0001745 249 0.278
eye photoreceptor cell development GO:0042462 81 0.244
eye morphogenesis GO:0048592 260 0.239
photoreceptor cell differentiation GO:0046530 170 0.225
eye photoreceptor cell differentiation GO:0001754 145 0.218
sensory organ morphogenesis GO:0090596 260 0.173
tube morphogenesis GO:0035239 191 0.145
Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.133
tube development GO:0035295 244 0.132
Mouse
morphogenesis of a polarized epithelium GO:0001738 93 0.127
Fly
regulation of multicellular organismal development GO:2000026 414 0.120
Mouse
photoreceptor cell development GO:0042461 96 0.118
compound eye photoreceptor development GO:0042051 78 0.117
negative regulation of cellular metabolic process GO:0031324 382 0.109
Mouse
epithelial cell differentiation GO:0030855 322 0.103
Fly
establishment or maintenance of cell polarity GO:0007163 167 0.091
regulation of organ morphogenesis GO:2000027 78 0.079
death GO:0016265 284 0.077
cell proliferation GO:0008283 299 0.074
embryonic morphogenesis GO:0048598 206 0.072
regionalization GO:0003002 416 0.070
small gtpase mediated signal transduction GO:0007264 88 0.070
positive regulation of signal transduction GO:0009967 223 0.069
single organism behavior GO:0044708 391 0.066
intracellular signal transduction GO:0035556 300 0.066
positive regulation of response to stimulus GO:0048584 323 0.064
digestive system development GO:0055123 149 0.063
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.063
Mouse
regulation of cell differentiation GO:0045595 302 0.060
Mouse
neural precursor cell proliferation GO:0061351 75 0.058
tissue morphogenesis GO:0048729 297 0.057
Mouse Fly
protein modification process GO:0036211 438 0.056
regulation of mitotic cell cycle GO:0007346 190 0.054
transcription from rna polymerase ii promoter GO:0006366 368 0.053
Mouse
regulation of ras protein signal transduction GO:0046578 93 0.053
morphogenesis of an epithelium GO:0002009 276 0.053
Mouse Fly
establishment of tissue polarity GO:0007164 87 0.053
Fly
cell division GO:0051301 248 0.051
catabolic process GO:0009056 409 0.051
regulation of cell morphogenesis GO:0022604 163 0.049
regulation of small gtpase mediated signal transduction GO:0051056 93 0.048
retina development in camera type eye GO:0060041 4 0.047
regulation of phosphorus metabolic process GO:0051174 210 0.047
apoptotic process GO:0006915 159 0.047
positive regulation of rna biosynthetic process GO:1902680 266 0.047
Mouse
notch signaling pathway GO:0007219 120 0.047
Mouse
nuclear division GO:0000280 332 0.046
neuroblast proliferation GO:0007405 74 0.045
ras protein signal transduction GO:0007265 88 0.044
cellular catabolic process GO:0044248 372 0.044
regulation of nervous system development GO:0051960 248 0.044
cellular macromolecule catabolic process GO:0044265 136 0.043
phosphorylation GO:0016310 294 0.042
organonitrogen compound metabolic process GO:1901564 318 0.042
negative regulation of developmental process GO:0051093 201 0.041
Mouse
organelle fission GO:0048285 340 0.041
negative regulation of nucleic acid templated transcription GO:1903507 240 0.040
Mouse
cell death GO:0008219 279 0.040
neuronal stem cell division GO:0036445 35 0.040
programmed cell death GO:0012501 257 0.040
antimicrobial humoral response GO:0019730 99 0.040
negative regulation of cellular biosynthetic process GO:0031327 277 0.040
Mouse
regulation of cell death GO:0010941 173 0.039
establishment of planar polarity GO:0001736 87 0.039
Fly
regulation of neurogenesis GO:0050767 158 0.039
mapk cascade GO:0000165 107 0.039
kidney development GO:0001822 3 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.039
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.038
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.038
digestive tract morphogenesis GO:0048546 127 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.037
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.037
Mouse
digestive tract development GO:0048565 149 0.036
negative regulation of transcription dna templated GO:0045892 237 0.036
Mouse
eye photoreceptor cell fate commitment GO:0042706 37 0.036
establishment of ommatidial planar polarity GO:0042067 49 0.035
negative regulation of signaling GO:0023057 219 0.035
regulation of intracellular signal transduction GO:1902531 236 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.034
Mouse
regulation of cell cycle phase transition GO:1901987 130 0.034
purine ribonucleoside metabolic process GO:0046128 127 0.033
organelle localization GO:0051640 148 0.033
regulation of cell cycle GO:0051726 291 0.032
cell cycle phase transition GO:0044770 140 0.032
positive regulation of biosynthetic process GO:0009891 316 0.031
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.031
negative regulation of signal transduction GO:0009968 206 0.031
positive regulation of catabolic process GO:0009896 105 0.031
regulation of localization GO:0032879 275 0.029
regulation of apoptotic process GO:0042981 130 0.029
embryonic pattern specification GO:0009880 174 0.029
positive regulation of rna metabolic process GO:0051254 271 0.029
Mouse
synapse assembly GO:0007416 143 0.029
negative regulation of gene expression GO:0010629 387 0.029
Mouse
positive regulation of signaling GO:0023056 243 0.029
nucleobase containing compound catabolic process GO:0034655 165 0.029
compound eye photoreceptor fate commitment GO:0001752 36 0.028
chaeta development GO:0022416 97 0.027
Fly
developmental programmed cell death GO:0010623 138 0.027
establishment of localization in cell GO:0051649 402 0.027
positive regulation of cellular catabolic process GO:0031331 95 0.027
organic substance catabolic process GO:1901575 308 0.026
camera type eye morphogenesis GO:0048593 2 0.026
negative regulation of programmed cell death GO:0043069 72 0.026
positive regulation of cell communication GO:0010647 250 0.026
epithelial tube morphogenesis GO:0060562 88 0.026
Mouse
regulation of phosphorylation GO:0042325 147 0.025
single organism catabolic process GO:0044712 228 0.025
neurological system process GO:0050877 358 0.025
neuroblast division GO:0055057 35 0.025
synaptic transmission GO:0007268 288 0.025
endocytosis GO:0006897 310 0.025
purine containing compound catabolic process GO:0072523 112 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.025
Mouse
stem cell differentiation GO:0048863 117 0.024
Fly
negative regulation of cell communication GO:0010648 223 0.024
cognition GO:0050890 141 0.024
rna splicing GO:0008380 83 0.024
Human
compound eye cone cell fate commitment GO:0042676 5 0.024
regulation of cellular component biogenesis GO:0044087 201 0.023
spermatogenesis GO:0007283 200 0.023
nucleobase containing small molecule metabolic process GO:0055086 174 0.023
response to oxygen containing compound GO:1901700 200 0.023
imaginal disc derived appendage development GO:0048737 399 0.023
Fly
purine nucleoside metabolic process GO:0042278 127 0.023
respiratory system development GO:0060541 213 0.023
regulation of behavior GO:0050795 75 0.023
adult behavior GO:0030534 137 0.023
regulation of catabolic process GO:0009894 170 0.023
proteolysis GO:0006508 192 0.022
immune response GO:0006955 246 0.022
negative regulation of erbb signaling pathway GO:1901185 29 0.022
asymmetric stem cell division GO:0098722 49 0.022
organelle fusion GO:0048284 46 0.022
axis specification GO:0009798 167 0.022
organelle membrane fusion GO:0090174 16 0.022
establishment of organelle localization GO:0051656 122 0.022
positive regulation of gtpase activity GO:0043547 43 0.022
locomotory behavior GO:0007626 176 0.022
anatomical structure homeostasis GO:0060249 97 0.022
cellular response to external stimulus GO:0071496 66 0.021
regulation of catalytic activity GO:0050790 185 0.021
regulation of cell division GO:0051302 72 0.021
enzyme linked receptor protein signaling pathway GO:0007167 179 0.021
Fly
purine nucleoside catabolic process GO:0006152 112 0.021
erbb signaling pathway GO:0038127 58 0.021
Fly
phagocytosis GO:0006909 215 0.021
macromolecule catabolic process GO:0009057 161 0.021
associative learning GO:0008306 65 0.020
epithelial cell development GO:0002064 274 0.020
protein localization GO:0008104 284 0.020
appendage development GO:0048736 401 0.020
Fly
glycosyl compound catabolic process GO:1901658 112 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
camera type eye development GO:0043010 4 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
cellular response to extracellular stimulus GO:0031668 64 0.019
glycosyl compound metabolic process GO:1901657 127 0.019
signal transduction by phosphorylation GO:0023014 107 0.019
epidermal growth factor receptor signaling pathway GO:0007173 58 0.019
Fly
nucleotide metabolic process GO:0009117 161 0.019
regulation of embryonic development GO:0045995 68 0.019
cellular response to nutrient levels GO:0031669 62 0.019
dendrite morphogenesis GO:0048813 199 0.019
somatic muscle development GO:0007525 66 0.019
embryonic hindgut morphogenesis GO:0048619 48 0.019
regulation of mapk cascade GO:0043408 92 0.019
vesicle mediated transport GO:0016192 381 0.018
appendage morphogenesis GO:0035107 397 0.018
Fly
carbohydrate derivative metabolic process GO:1901135 217 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
Mouse
leg disc development GO:0035218 92 0.018
negative regulation of cell death GO:0060548 81 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
regulation of multi organism process GO:0043900 131 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
cell fate specification GO:0001708 71 0.018
cell migration GO:0016477 238 0.018
Fly
retina morphogenesis in camera type eye GO:0060042 2 0.018
regulation of erbb signaling pathway GO:1901184 42 0.018
regulation of molecular function GO:0065009 217 0.018
regulation of organelle organization GO:0033043 196 0.017
regulation of epithelial cell differentiation GO:0030856 4 0.017
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.017
regulation of notch signaling pathway GO:0008593 100 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
Fly
regulation of photoreceptor cell differentiation GO:0046532 34 0.017
neural retina development GO:0003407 4 0.017
aromatic compound catabolic process GO:0019439 166 0.017
rhabdomere development GO:0042052 38 0.017
regulation of wnt signaling pathway GO:0030111 68 0.017
regulation of establishment of planar polarity GO:0090175 22 0.017
synapse organization GO:0050808 196 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.016
learning GO:0007612 75 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
regulation of rna splicing GO:0043484 69 0.016
Human
renal system development GO:0072001 72 0.016
stem cell proliferation GO:0072089 88 0.016
nucleoside catabolic process GO:0009164 112 0.016
response to extracellular stimulus GO:0009991 116 0.016
compound eye cone cell differentiation GO:0042675 13 0.016
innate immune response activating signal transduction GO:0002758 2 0.016
eye antennal disc development GO:0035214 60 0.016
gtp catabolic process GO:0006184 72 0.016
regulation of programmed cell death GO:0043067 152 0.016
mitotic nuclear division GO:0007067 213 0.015
regulation of cellular response to stress GO:0080135 89 0.015
gtp metabolic process GO:0046039 72 0.015
positive regulation of gene expression GO:0010628 290 0.015
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
regulation of neuron differentiation GO:0045664 103 0.015
asymmetric protein localization GO:0008105 33 0.015
ion transport GO:0006811 145 0.015
regulation of mrna processing GO:0050684 71 0.015
Human
germarium derived egg chamber formation GO:0007293 101 0.015
cell maturation GO:0048469 144 0.015
negative regulation of neurogenesis GO:0050768 53 0.015
negative regulation of nervous system development GO:0051961 92 0.015
renal tubule development GO:0061326 64 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
Mouse
regulation of cell development GO:0060284 215 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.014
Mouse
ribonucleotide catabolic process GO:0009261 109 0.014
cellular protein modification process GO:0006464 438 0.014
macroautophagy GO:0016236 42 0.014
small molecule metabolic process GO:0044281 305 0.014
regulation of transport GO:0051049 181 0.014
ommatidial rotation GO:0016318 20 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
r3 r4 cell differentiation GO:0048056 12 0.014
urogenital system development GO:0001655 72 0.014
membrane fusion GO:0061025 42 0.014
humoral immune response GO:0006959 117 0.014
eggshell formation GO:0030703 105 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
nephron epithelium development GO:0072009 3 0.014
cell motility GO:0048870 251 0.014
Fly
heterocycle catabolic process GO:0046700 166 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
protein ubiquitination GO:0016567 70 0.014
spermatid development GO:0007286 98 0.014
cellular homeostasis GO:0019725 80 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
Mouse
regulation of mrna splicing via spliceosome GO:0048024 64 0.014
Human
regulation of cellular protein metabolic process GO:0032268 243 0.014
dendrite development GO:0016358 204 0.014
positive regulation of ras gtpase activity GO:0032320 36 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.013
regulation of cell shape GO:0008360 113 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
nitrogen compound transport GO:0071705 85 0.013
kidney epithelium development GO:0072073 3 0.013
stem cell maintenance GO:0019827 67 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
positive regulation of gtp catabolic process GO:0033126 43 0.013
mitotic dna integrity checkpoint GO:0044774 75 0.013
positive regulation of nucleoside metabolic process GO:0045979 47 0.013
olfactory behavior GO:0042048 97 0.013
stem cell division GO:0017145 69 0.013
pole plasm mrna localization GO:0019094 49 0.013
peripheral nervous system development GO:0007422 52 0.013
Fly
organic cyclic compound catabolic process GO:1901361 168 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
protein phosphorylation GO:0006468 169 0.013
positive regulation of nucleotide catabolic process GO:0030813 46 0.013
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
purine containing compound metabolic process GO:0072521 155 0.013
rna processing GO:0006396 147 0.013
Human
mitotic sister chromatid segregation GO:0000070 87 0.013
oocyte anterior posterior axis specification GO:0007314 72 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
neuron fate commitment GO:0048663 50 0.012
ovarian follicle cell development GO:0030707 248 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
regulation of hydrolase activity GO:0051336 97 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
gastrulation GO:0007369 70 0.012
anterior posterior axis specification GO:0009948 109 0.012
cellular response to carbohydrate stimulus GO:0071322 4 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
macromolecular complex assembly GO:0065003 256 0.012
chromatin organization GO:0006325 207 0.012
dna templated transcription initiation GO:0006352 25 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
homeostatic process GO:0042592 199 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
actin filament based process GO:0030029 220 0.012
gastrulation with mouth forming first GO:0001703 36 0.012
positive regulation of molecular function GO:0044093 136 0.012
negative regulation of cell cycle GO:0045786 116 0.012
chromosome organization GO:0051276 360 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
nephron epithelium morphogenesis GO:0072088 3 0.012
centrosome duplication GO:0051298 121 0.012
asymmetric neuroblast division GO:0055059 33 0.012
apical constriction GO:0003383 18 0.012
mitotic g2 dna damage checkpoint GO:0007095 69 0.012
dna metabolic process GO:0006259 227 0.012
regulation of cell proliferation GO:0042127 163 0.012
cellular pigmentation GO:0033059 12 0.012
rhythmic behavior GO:0007622 76 0.011
mitotic cytokinesis GO:0000281 50 0.011
negative regulation of notch signaling pathway GO:0045746 41 0.011
photoreceptor cell fate commitment GO:0046552 41 0.011
malpighian tubule development GO:0072002 64 0.011
nephron development GO:0072006 3 0.011
mitotic spindle organization GO:0007052 220 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
regulation of response to stress GO:0080134 200 0.011
sister chromatid segregation GO:0000819 92 0.011
glial cell differentiation GO:0010001 35 0.011
Fly
guanosine containing compound metabolic process GO:1901068 74 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
guanosine containing compound catabolic process GO:1901069 74 0.011
regulation of mitosis GO:0007088 56 0.011
regulation of synaptic transmission GO:0050804 69 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
single organism membrane fusion GO:0044801 42 0.011
oocyte differentiation GO:0009994 145 0.011
positive regulation of response to external stimulus GO:0032103 44 0.011
meiotic cell cycle GO:0051321 171 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
antibacterial peptide biosynthetic process GO:0002780 22 0.011
regulation of protein metabolic process GO:0051246 256 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
gland morphogenesis GO:0022612 145 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
salivary gland morphogenesis GO:0007435 145 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
renal tubule morphogenesis GO:0061333 44 0.011
cellular response to starvation GO:0009267 61 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
axon development GO:0061564 297 0.011
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
Mouse
meiotic nuclear division GO:0007126 151 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
nucleotide catabolic process GO:0009166 109 0.010
cell fate determination GO:0001709 91 0.010
Fly
response to external biotic stimulus GO:0043207 293 0.010
Fly
embryonic organ development GO:0048568 50 0.010
germ line stem cell maintenance GO:0030718 50 0.010
retinal cell programmed cell death GO:0046666 25 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
positive regulation of retinal cell programmed cell death GO:0046670 9 0.010
morphogenesis of embryonic epithelium GO:0016331 94 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
regulation of protein modification process GO:0031399 112 0.010
mitotic dna damage checkpoint GO:0044773 74 0.010
regulation of ras gtpase activity GO:0032318 38 0.010
protein catabolic process GO:0030163 101 0.010
regulation of cellular localization GO:0060341 136 0.010
positive regulation of cell death GO:0010942 69 0.010
regulation of cell cycle process GO:0010564 181 0.010

nito disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.010
cancer DOID:162 0 0.010