Drosophila melanogaster

102 known processes

Smox (Dmel_CG2262)

Smad on X

(Aliases: dsmad2,dSmad2,Dmel\CG2262,SMOX,dSMAD2,DSmad2,l(1)G0348,ted,SMAD2,Sad,DSMAD2,Smad2,smad2,sad,CG2262,tmp,smox)

Smox biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic morphogenesis GO:0048598 206 0.991
Fly
axon guidance GO:0007411 233 0.976
phosphorylation GO:0016310 294 0.976
Fly
taxis GO:0042330 304 0.974
stem cell differentiation GO:0048863 117 0.972
Fly
regulation of intracellular signal transduction GO:1902531 236 0.970
intracellular signal transduction GO:0035556 300 0.966
Fly
growth GO:0040007 359 0.954
Worm Fly
cell migration GO:0016477 238 0.953
Fly
embryonic development via the syncytial blastoderm GO:0001700 148 0.952
developmental growth GO:0048589 280 0.939
Worm Fly
regulation of growth GO:0040008 233 0.938
Worm Fly
muscle cell differentiation GO:0042692 103 0.926
extracellular structure organization GO:0043062 46 0.922
chemotaxis GO:0006935 249 0.921
cell motility GO:0048870 251 0.914
Fly
multicellular organismal aging GO:0010259 140 0.899
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.890
Fly
determination of adult lifespan GO:0008340 137 0.887
regulation of mitotic cell cycle GO:0007346 190 0.880
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.880
Fly
regulation of developmental growth GO:0048638 174 0.870
Worm Fly
eye development GO:0001654 323 0.861
Fly
protein modification process GO:0036211 438 0.858
regulation of localization GO:0032879 275 0.854
regulation of cell differentiation GO:0045595 302 0.849
Fly
positive regulation of cell communication GO:0010647 250 0.847
ameboidal type cell migration GO:0001667 151 0.845
actin filament based process GO:0030029 220 0.829
oxoacid metabolic process GO:0043436 103 0.827
regulation of multicellular organism growth GO:0040014 40 0.818
Worm
positive regulation of response to stimulus GO:0048584 323 0.817
epithelial cell migration GO:0010631 148 0.817
cellular protein modification process GO:0006464 438 0.814
response to organic substance GO:0010033 284 0.806
Fly
embryo development ending in birth or egg hatching GO:0009792 152 0.796
positive regulation of developmental process GO:0051094 143 0.783
Worm Fly
regulation of gtpase activity GO:0043087 44 0.780
stem cell division GO:0017145 69 0.761
Fly
regulation of cellular amine metabolic process GO:0033238 3 0.744
stem cell proliferation GO:0072089 88 0.730
immune system process GO:0002376 347 0.729
positive regulation of molecular function GO:0044093 136 0.723
negative regulation of cell communication GO:0010648 223 0.722
Fly
regulation of mapk cascade GO:0043408 92 0.709
catabolic process GO:0009056 409 0.697
regulation of cellular protein metabolic process GO:0032268 243 0.697
regulation of phosphorylation GO:0042325 147 0.670
Fly
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.660
positive regulation of multicellular organismal process GO:0051240 143 0.657
Worm Fly
regulation of phosphorus metabolic process GO:0051174 210 0.649
Fly
negative regulation of developmental process GO:0051093 201 0.645
Fly
aging GO:0007568 143 0.644
regulation of phosphate metabolic process GO:0019220 210 0.621
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.615
Fly
cellular response to chemical stimulus GO:0070887 199 0.610
Fly
cardiocyte differentiation GO:0035051 29 0.608
regulation of catabolic process GO:0009894 170 0.603
polysaccharide metabolic process GO:0005976 11 0.601
digestive system development GO:0055123 149 0.597
Fly
positive regulation of signaling GO:0023056 243 0.592
regulation of cellular localization GO:0060341 136 0.588
cell division GO:0051301 248 0.588
Fly
morphogenesis of embryonic epithelium GO:0016331 94 0.584
positive regulation of signal transduction GO:0009967 223 0.583
regulation of imaginal disc growth GO:0045570 26 0.581
axonogenesis GO:0007409 290 0.577
regionalization GO:0003002 416 0.553
Fly
negative regulation of signal transduction GO:0009968 206 0.550
Fly
positive regulation of phosphorus metabolic process GO:0010562 139 0.544
heart development GO:0007507 82 0.537
extracellular matrix organization GO:0030198 32 0.531
immune system development GO:0002520 57 0.517
positive regulation of proteolysis GO:0045862 52 0.512
negative regulation of cell cycle phase transition GO:1901988 103 0.507
Fly
posttranscriptional regulation of gene expression GO:0010608 145 0.500
regulation of protein metabolic process GO:0051246 256 0.496
cell death GO:0008219 279 0.493
enzyme linked receptor protein signaling pathway GO:0007167 179 0.491
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.487
Fly
central nervous system development GO:0007417 201 0.487
protein phosphorylation GO:0006468 169 0.481
defense response GO:0006952 300 0.466
positive regulation of transcription dna templated GO:0045893 266 0.462
Fly
localization of cell GO:0051674 257 0.461
Fly
digestive tract development GO:0048565 149 0.450
Fly
regulation of cellular catabolic process GO:0031329 157 0.446
embryonic organ development GO:0048568 50 0.427
organic acid metabolic process GO:0006082 103 0.427
organelle fission GO:0048285 340 0.426
response to abiotic stimulus GO:0009628 341 0.423
developmental pigmentation GO:0048066 68 0.417
mitotic cell cycle phase transition GO:0044772 138 0.400
Fly
gland development GO:0048732 191 0.399
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.397
Fly
protein localization to nucleus GO:0034504 55 0.397
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.396
Fly
cellular ketone metabolic process GO:0042180 24 0.394
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.389
Fly
mesenchymal cell differentiation GO:0048762 1 0.387
single organism catabolic process GO:0044712 228 0.387
cellular response to organic substance GO:0071310 132 0.384
Fly
neural precursor cell proliferation GO:0061351 75 0.380
signal transduction by phosphorylation GO:0023014 107 0.372
cell growth GO:0016049 108 0.370
Fly
eye morphogenesis GO:0048592 260 0.370
Fly
macromolecule catabolic process GO:0009057 161 0.365
axon development GO:0061564 297 0.365
positive regulation of cellular protein metabolic process GO:0032270 118 0.362
cellular catabolic process GO:0044248 372 0.362
cell projection assembly GO:0030031 94 0.361
protein localization GO:0008104 284 0.353
regulation of wnt signaling pathway GO:0030111 68 0.352
dorsal ventral pattern formation GO:0009953 133 0.347
Fly
positive regulation of lipid metabolic process GO:0045834 4 0.343
tissue morphogenesis GO:0048729 297 0.333
Fly
hemopoiesis GO:0030097 46 0.325
regulation of cellular amino acid metabolic process GO:0006521 0 0.321
regulation of cell growth GO:0001558 43 0.321
pigmentation GO:0043473 75 0.308
protein complex biogenesis GO:0070271 201 0.306
cell adhesion GO:0007155 136 0.300
cell junction organization GO:0034330 57 0.296
hematopoietic progenitor cell differentiation GO:0002244 1 0.294
developmental maturation GO:0021700 172 0.286
cardiovascular system development GO:0072358 82 0.285
positive regulation of multicellular organism growth GO:0040018 21 0.281
Worm
muscle structure development GO:0061061 224 0.278
Fly
brain development GO:0007420 120 0.271
regulation of anatomical structure morphogenesis GO:0022603 242 0.270
cellular response to dna damage stimulus GO:0006974 223 0.269
regulation of gtp catabolic process GO:0033124 44 0.266
negative regulation of catabolic process GO:0009895 36 0.265
epithelium migration GO:0090132 148 0.263
regulation of bmp signaling pathway GO:0030510 23 0.263
negative regulation of growth GO:0045926 84 0.262
Fly
anterior posterior pattern specification imaginal disc GO:0007448 16 0.260
Fly
amine metabolic process GO:0009308 12 0.260
stem cell maintenance GO:0019827 67 0.258
Fly
camera type eye development GO:0043010 4 0.256
positive regulation of protein metabolic process GO:0051247 128 0.255
negative regulation of cell differentiation GO:0045596 143 0.255
Fly
positive regulation of hydrolase activity GO:0051345 78 0.252
positive regulation of intracellular signal transduction GO:1902533 116 0.251
tissue migration GO:0090130 155 0.248
segmentation GO:0035282 207 0.246
Fly
regulation of cell cycle GO:0051726 291 0.242
imaginal disc derived appendage morphogenesis GO:0035114 395 0.240
positive regulation of phosphate metabolic process GO:0045937 139 0.239
cell fate determination GO:0001709 91 0.238
regulation of protein localization GO:0032880 76 0.236
circulatory system development GO:0072359 82 0.234
cellular macromolecule localization GO:0070727 220 0.232
retinal ganglion cell axon guidance GO:0031290 12 0.227
Fly
exocrine system development GO:0035272 162 0.226
larval development GO:0002164 104 0.224
Fly
positive regulation of developmental growth GO:0048639 62 0.223
Worm Fly
carboxylic acid metabolic process GO:0019752 92 0.217
positive regulation of biosynthetic process GO:0009891 316 0.215
Fly
positive regulation of cell development GO:0010720 61 0.215
regulation of cysteine type endopeptidase activity GO:2000116 27 0.214
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.213
protein modification by small protein conjugation or removal GO:0070647 106 0.209
regulation of innate immune response GO:0045088 71 0.208
connective tissue development GO:0061448 3 0.207
neuron projection guidance GO:0097485 241 0.206
neuroblast proliferation GO:0007405 74 0.206
regulation of intracellular protein transport GO:0033157 46 0.206
stem cell development GO:0048864 79 0.205
Fly
regulation of nucleotide catabolic process GO:0030811 48 0.202
cellular amino acid metabolic process GO:0006520 61 0.202
mapk cascade GO:0000165 107 0.197
innate immune response GO:0045087 144 0.195
proteolysis GO:0006508 192 0.194
molting cycle process GO:0022404 29 0.191
cell fate specification GO:0001708 71 0.189
Fly
positive regulation of phosphorylation GO:0042327 87 0.188
phenol containing compound metabolic process GO:0018958 57 0.185
protein catabolic process GO:0030163 101 0.185
regulation of synapse structure and activity GO:0050803 128 0.184
Fly
biological adhesion GO:0022610 138 0.184
gastrulation GO:0007369 70 0.184
Fly
striated muscle cell differentiation GO:0051146 90 0.184
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.183
Fly
molting cycle GO:0042303 56 0.182
macromolecular complex assembly GO:0065003 256 0.182
regulation of transferase activity GO:0051338 58 0.178
gliogenesis GO:0042063 80 0.178
immune response regulating signaling pathway GO:0002764 2 0.172
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.172
organonitrogen compound metabolic process GO:1901564 318 0.172
regulation of molecular function GO:0065009 217 0.170
protein targeting to nucleus GO:0044744 51 0.168
cell proliferation GO:0008283 299 0.166
regulation of cell cycle phase transition GO:1901987 130 0.166
Fly
camera type eye morphogenesis GO:0048593 2 0.164
activin receptor signaling pathway GO:0032924 6 0.164
extrinsic apoptotic signaling pathway GO:0097191 1 0.163
positive regulation of cell adhesion GO:0045785 10 0.163
actin cytoskeleton reorganization GO:0031532 22 0.163
regulation of protein modification process GO:0031399 112 0.162
negative regulation of phosphorylation GO:0042326 35 0.160
negative regulation of signaling GO:0023057 219 0.159
Fly
cellular protein catabolic process GO:0044257 83 0.153
negative regulation of cellular protein metabolic process GO:0032269 85 0.152
regulation of transport GO:0051049 181 0.151
stress activated mapk cascade GO:0051403 52 0.148
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.148
regulation of hydrolase activity GO:0051336 97 0.146
positive regulation of bmp signaling pathway GO:0030513 5 0.145
regulation of stress activated mapk cascade GO:0032872 41 0.144
regulation of mitotic cell cycle phase transition GO:1901990 130 0.142
Fly
regulation of small gtpase mediated signal transduction GO:0051056 93 0.142
protein complex assembly GO:0006461 200 0.142
immune response GO:0006955 246 0.142
regulation of immune system process GO:0002682 176 0.141
cellular amine metabolic process GO:0044106 12 0.141
regulation of stem cell proliferation GO:0072091 40 0.140
positive regulation of cellular component organization GO:0051130 156 0.139
Fly
organic substance catabolic process GO:1901575 308 0.138
establishment of nucleus localization GO:0040023 26 0.137
polysaccharide biosynthetic process GO:0000271 7 0.137
regulation of response to stress GO:0080134 200 0.137
regulation of cell cycle process GO:0010564 181 0.135
Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.134
Fly
regulation of cell proliferation GO:0042127 163 0.133
regulation of neurogenesis GO:0050767 158 0.132
regulation of organ morphogenesis GO:2000027 78 0.131
nucleus localization GO:0051647 34 0.130
stress activated protein kinase signaling cascade GO:0031098 55 0.129
cellular response to growth factor stimulus GO:0071363 30 0.129
Fly
regulation of protein serine threonine kinase activity GO:0071900 25 0.128
ras protein signal transduction GO:0007265 88 0.127
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.127
regulation of cellular response to stress GO:0080135 89 0.127
secretion GO:0046903 109 0.125
positive regulation of catabolic process GO:0009896 105 0.125
protein import into nucleus GO:0006606 51 0.124
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.124
cell cycle checkpoint GO:0000075 95 0.124
negative regulation of epithelial cell proliferation GO:0050680 4 0.123
chitin based cuticle sclerotization GO:0007593 19 0.123
positive regulation of rna metabolic process GO:0051254 271 0.122
Fly
purine nucleoside triphosphate metabolic process GO:0009144 119 0.122
positive regulation of nucleic acid templated transcription GO:1903508 266 0.122
Fly
positive regulation of catalytic activity GO:0043085 118 0.120
positive regulation of cellular catabolic process GO:0031331 95 0.119
pigment metabolic process GO:0042440 84 0.119
tube development GO:0035295 244 0.118
Fly
membrane organization GO:0061024 112 0.117
positive regulation of growth GO:0045927 75 0.116
Worm Fly
cell junction assembly GO:0034329 42 0.115
cellular response to endogenous stimulus GO:0071495 80 0.115
Fly
gtp catabolic process GO:0006184 72 0.115
regulation of protein phosphorylation GO:0001932 64 0.115
peptidyl threonine phosphorylation GO:0018107 2 0.114
nucleoside phosphate catabolic process GO:1901292 110 0.114
hindbrain development GO:0030902 2 0.114
death GO:0016265 284 0.111
dorsal closure GO:0007391 79 0.110
response to lipopolysaccharide GO:0032496 4 0.109
mitotic cell cycle checkpoint GO:0007093 88 0.108
nephron development GO:0072006 3 0.107
regulation of nucleoside metabolic process GO:0009118 50 0.107
secretion by cell GO:0032940 101 0.106
regulation of cellular response to insulin stimulus GO:1900076 17 0.106
positive regulation of cell migration GO:0030335 2 0.105
meiotic nuclear division GO:0007126 151 0.105
hematopoietic or lymphoid organ development GO:0048534 57 0.104
protein modification by small protein conjugation GO:0032446 79 0.104
carbohydrate derivative catabolic process GO:1901136 118 0.102
regulation of epithelial cell proliferation GO:0050678 4 0.102
salivary gland development GO:0007431 162 0.101
positive regulation of peptidase activity GO:0010952 29 0.100
cellular lipid metabolic process GO:0044255 83 0.100
positive regulation of jun kinase activity GO:0043507 4 0.100
positive regulation of cell growth GO:0030307 19 0.099
positive regulation of protein complex assembly GO:0031334 22 0.099
purine nucleotide catabolic process GO:0006195 109 0.098
ribonucleoside triphosphate metabolic process GO:0009199 119 0.097
mesenchymal cell development GO:0014031 1 0.096
body morphogenesis GO:0010171 2 0.094
activation of protein kinase activity GO:0032147 12 0.094
regulation of programmed cell death GO:0043067 152 0.094
gtp metabolic process GO:0046039 72 0.093
single organism cellular localization GO:1902580 180 0.093
organic hydroxy compound metabolic process GO:1901615 83 0.092
guanosine containing compound catabolic process GO:1901069 74 0.092
phagocytosis GO:0006909 215 0.090
regulation of ras protein signal transduction GO:0046578 93 0.090
response to organonitrogen compound GO:0010243 75 0.089
small molecule metabolic process GO:0044281 305 0.088
small gtpase mediated signal transduction GO:0007264 88 0.088
actin cytoskeleton organization GO:0030036 206 0.087
cellular carbohydrate metabolic process GO:0044262 22 0.087
single organismal cell cell adhesion GO:0016337 45 0.086
glycosyl compound metabolic process GO:1901657 127 0.085
negative regulation of immune system process GO:0002683 50 0.084
homeostatic process GO:0042592 199 0.084
axis specification GO:0009798 167 0.082
Fly
regulation of cell death GO:0010941 173 0.082
response to nutrient levels GO:0031667 114 0.082
kidney development GO:0001822 3 0.081
regulation of kinase activity GO:0043549 53 0.080
posttranscriptional gene silencing GO:0016441 46 0.080
unidimensional cell growth GO:0009826 15 0.080
Fly
regulation of nervous system development GO:0051960 248 0.079
Fly
regulation of protein kinase activity GO:0045859 51 0.078
regulation of catalytic activity GO:0050790 185 0.078
response to glucose GO:0009749 2 0.077
purine nucleoside catabolic process GO:0006152 112 0.076
positive regulation of mapk cascade GO:0043410 63 0.075
organelle localization GO:0051640 148 0.074
negative regulation of autophagy GO:0010507 16 0.073
cellular protein localization GO:0034613 160 0.073
renal system development GO:0072001 72 0.073
Fly
regulation of jnk cascade GO:0046328 40 0.073
nucleoside metabolic process GO:0009116 127 0.072
endomembrane system organization GO:0010256 119 0.072
negative regulation of protein metabolic process GO:0051248 85 0.072
cell cell junction organization GO:0045216 55 0.072
peptidyl amino acid modification GO:0018193 105 0.071
jak stat cascade GO:0007259 49 0.071
gene silencing by mirna GO:0035195 22 0.071
posttranscriptional gene silencing by rna GO:0035194 45 0.071
oviposition GO:0018991 19 0.071
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.071
chromosome organization GO:0051276 360 0.070
compound eye development GO:0048749 307 0.070
Fly
striated muscle tissue development GO:0014706 27 0.070
regulation of neuron differentiation GO:0045664 103 0.069
chromatin organization GO:0006325 207 0.069
regulation of immune response GO:0050776 118 0.069
regulation of cellular ketone metabolic process GO:0010565 3 0.068
positive regulation of rna biosynthetic process GO:1902680 266 0.068
Fly
positive regulation of gtpase activity GO:0043547 43 0.067
regulation of histone acetylation GO:0035065 7 0.067
purine nucleoside triphosphate catabolic process GO:0009146 108 0.067
negative regulation of phosphate metabolic process GO:0045936 45 0.067
gene silencing by rna GO:0031047 57 0.067
response to extracellular stimulus GO:0009991 116 0.067
nuclear division GO:0000280 332 0.066
regulation of cell development GO:0060284 215 0.066
regulation of cytoplasmic transport GO:1903649 47 0.066
digestive tract morphogenesis GO:0048546 127 0.066
Fly
ribonucleoside metabolic process GO:0009119 127 0.066
endocytosis GO:0006897 310 0.066
compound eye photoreceptor cell differentiation GO:0001751 140 0.065
bmp signaling pathway GO:0030509 27 0.065
Fly
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.065
mesoderm development GO:0007498 78 0.064
carbohydrate derivative metabolic process GO:1901135 217 0.064
regulation of vesicle mediated transport GO:0060627 59 0.064
response to monosaccharide GO:0034284 4 0.064
cellular protein complex assembly GO:0043623 71 0.064
dendrite development GO:0016358 204 0.061
regulation of intracellular transport GO:0032386 64 0.061
retina development in camera type eye GO:0060041 4 0.061
maintenance of protein location in cell GO:0032507 26 0.060
negative regulation of mitotic cell cycle GO:0045930 109 0.058
Worm Fly
endodermal cell fate commitment GO:0001711 3 0.058
Fly
regulation of glial cell proliferation GO:0060251 11 0.058
regulation of translation GO:0006417 56 0.058
negative regulation of phosphorus metabolic process GO:0010563 45 0.057
negative regulation of cell proliferation GO:0008285 69 0.057
endodermal cell differentiation GO:0035987 3 0.057
Fly
purine ribonucleotide metabolic process GO:0009150 145 0.057
spinal cord development GO:0021510 1 0.057
organophosphate metabolic process GO:0019637 195 0.057
negative regulation of cell death GO:0060548 81 0.057
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.055
regulation of epithelial cell differentiation GO:0030856 4 0.055
positive regulation of cell motility GO:2000147 3 0.055
positive regulation of cellular biosynthetic process GO:0031328 316 0.054
Fly
regulation of carbohydrate metabolic process GO:0006109 10 0.054
positive regulation of transport GO:0051050 92 0.053
dorsal ventral axon guidance GO:0033563 2 0.053
cardioblast differentiation GO:0010002 20 0.053
ribonucleoside catabolic process GO:0042454 112 0.052
regulation of epithelial cell migration GO:0010632 12 0.051
regulation of gliogenesis GO:0014013 11 0.051
vesicle mediated transport GO:0016192 381 0.051
erk1 and erk2 cascade GO:0070371 39 0.051
positive regulation of kinase activity GO:0033674 25 0.051
nucleoside triphosphate metabolic process GO:0009141 120 0.050
regulation of organelle organization GO:0033043 196 0.050
ribonucleoside triphosphate catabolic process GO:0009203 108 0.050
negative regulation of protein modification process GO:0031400 29 0.050
nucleoside catabolic process GO:0009164 112 0.049
establishment of protein localization GO:0045184 163 0.049
positive regulation of gtp catabolic process GO:0033126 43 0.049
negative regulation of gene expression GO:0010629 387 0.049
Fly
regulation of protein catabolic process GO:0042176 55 0.048
aromatic compound catabolic process GO:0019439 166 0.048
response to heat GO:0009408 63 0.047
regulation of ras gtpase activity GO:0032318 38 0.047
regulation of purine nucleotide catabolic process GO:0033121 48 0.047
regulation of protein acetylation GO:1901983 7 0.047
myotube differentiation GO:0014902 46 0.046
smad protein import into nucleus GO:0007184 11 0.046
multicellular organism growth GO:0035264 46 0.046
Worm
regulation of apoptotic process GO:0042981 130 0.046
glycosyl compound catabolic process GO:1901658 112 0.045
positive regulation of cellular component biogenesis GO:0044089 80 0.045
Fly
positive regulation of transferase activity GO:0051347 26 0.045
single organism nuclear import GO:1902593 51 0.045
cellular nitrogen compound catabolic process GO:0044270 165 0.045
guanosine containing compound metabolic process GO:1901068 74 0.045
response to radiation GO:0009314 155 0.044
ubiquitin dependent protein catabolic process GO:0006511 78 0.044
regulation of glial cell differentiation GO:0045685 1 0.044
epithelial cell differentiation GO:0030855 322 0.044
Fly
peptidyl tyrosine phosphorylation GO:0018108 24 0.044
regulation of neuron death GO:1901214 26 0.044
nucleocytoplasmic transport GO:0006913 72 0.043
mitotic nuclear division GO:0007067 213 0.043
positive regulation of protein phosphorylation GO:0001934 34 0.043
heterocycle catabolic process GO:0046700 166 0.043
programmed cell death GO:0012501 257 0.043
regulation of activin receptor signaling pathway GO:0032925 4 0.042
establishment of localization in cell GO:0051649 402 0.042
regulation of defense response GO:0031347 102 0.042
cell cycle phase transition GO:0044770 140 0.042
Fly
salivary gland morphogenesis GO:0007435 145 0.042
response to hormone GO:0009725 45 0.041
positive regulation of rab gtpase activity GO:0032851 7 0.041
defense response to bacterium GO:0042742 178 0.041
negative regulation of neurogenesis GO:0050768 53 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.041
positive regulation of protein kinase activity GO:0045860 25 0.040
developmental growth involved in morphogenesis GO:0060560 65 0.040
Fly
wing disc anterior posterior pattern formation GO:0048100 5 0.040
Fly
positive regulation of cellular component movement GO:0051272 11 0.039
regulation of developmental pigmentation GO:0048070 24 0.039
adult chitin containing cuticle pigmentation GO:0048085 16 0.038
adult behavior GO:0030534 137 0.038
regulation of neuron apoptotic process GO:0043523 16 0.038
cellular macromolecule catabolic process GO:0044265 136 0.038
wnt signaling pathway GO:0016055 98 0.038
cellular component disassembly GO:0022411 46 0.037
carbohydrate metabolic process GO:0005975 82 0.037
positive regulation of ras gtpase activity GO:0032320 36 0.037
response to wounding GO:0009611 94 0.036
response to growth factor GO:0070848 31 0.036
Fly
nucleoside triphosphate catabolic process GO:0009143 108 0.036
maintenance of location GO:0051235 73 0.036
adherens junction assembly GO:0034333 11 0.036
nerve development GO:0021675 6 0.036
ribonucleotide catabolic process GO:0009261 109 0.036
regulation of multicellular organismal development GO:2000026 414 0.036
neuron projection extension GO:1990138 32 0.035
anterior malpighian tubule development GO:0061327 12 0.035
positive regulation of immune system process GO:0002684 68 0.035
regulation of stem cell differentiation GO:2000736 14 0.035
somatic stem cell division GO:0048103 37 0.035
regulation of hemocyte proliferation GO:0035206 37 0.035
positive regulation of mitotic cell cycle GO:0045931 34 0.035
imaginal disc growth GO:0007446 37 0.035
respiratory system development GO:0060541 213 0.034
negative regulation of nervous system development GO:0051961 92 0.034
Fly
regulation of membrane potential GO:0042391 35 0.034
syncytium formation by plasma membrane fusion GO:0000768 43 0.034
positive regulation of organelle organization GO:0010638 65 0.034
chromatin modification GO:0016568 147 0.034
nucleoside phosphate metabolic process GO:0006753 162 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.034
protein acetylation GO:0006473 39 0.033
mushroom body development GO:0016319 70 0.033
locomotory behavior GO:0007626 176 0.033
response to endogenous stimulus GO:0009719 119 0.032
Fly
positive regulation of response to external stimulus GO:0032103 44 0.032
modification dependent macromolecule catabolic process GO:0043632 79 0.032
organ growth GO:0035265 56 0.032
chromosome separation GO:0051304 42 0.032
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.032
asymmetric stem cell division GO:0098722 49 0.032
rho protein signal transduction GO:0007266 14 0.031
regulation of insulin receptor signaling pathway GO:0046626 17 0.031
embryonic digestive tract development GO:0048566 5 0.031
purine containing compound metabolic process GO:0072521 155 0.031
negative regulation of cell cycle process GO:0010948 109 0.031
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.030
r7 cell differentiation GO:0045466 43 0.030
reproductive behavior GO:0019098 122 0.030
nitrogen compound transport GO:0071705 85 0.030
kidney epithelium development GO:0072073 3 0.030
negative regulation of molecular function GO:0044092 51 0.030
reactive oxygen species metabolic process GO:0072593 22 0.030
germ cell migration GO:0008354 43 0.030
response to biotic stimulus GO:0009607 294 0.030
filopodium assembly GO:0046847 33 0.030
tube morphogenesis GO:0035239 191 0.030
Fly
response to bacterium GO:0009617 198 0.030
stress fiber assembly GO:0043149 6 0.030
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.029
anterior posterior pattern specification GO:0009952 136 0.029
Fly
dna replication GO:0006260 48 0.029

Smox disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047