Drosophila melanogaster

24 known processes

Orc4 (Dmel_CG2917)

Origin recognition complex subunit 4

(Aliases: Dmel\CG2917,ORC4,ORC,DmORC4,CG2917,orc4,rDmORC)

Orc4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 227 0.229
dna conformation change GO:0071103 105 0.183
organelle fission GO:0048285 340 0.179
regulation of nervous system development GO:0051960 248 0.170
regulation of developmental growth GO:0048638 174 0.155
cellular response to dna damage stimulus GO:0006974 223 0.136
cellular catabolic process GO:0044248 372 0.133
meiosis i GO:0007127 59 0.129
catabolic process GO:0009056 409 0.127
regulation of cell cycle phase transition GO:1901987 130 0.115
negative regulation of gene expression GO:0010629 387 0.110
cellular macromolecule catabolic process GO:0044265 136 0.105
negative regulation of developmental process GO:0051093 201 0.095
negative regulation of rna metabolic process GO:0051253 251 0.094
organic substance catabolic process GO:1901575 308 0.082
reciprocal dna recombination GO:0035825 19 0.079
nucleobase containing compound catabolic process GO:0034655 165 0.076
nuclear division GO:0000280 332 0.073
organic cyclic compound catabolic process GO:1901361 168 0.067
dna packaging GO:0006323 91 0.065
regulation of anatomical structure morphogenesis GO:0022603 242 0.064
mitotic cytokinesis GO:0000281 50 0.064
regulation of molecular function GO:0065009 217 0.063
heterocycle catabolic process GO:0046700 166 0.060
cell death GO:0008219 279 0.058
cytoskeleton dependent cytokinesis GO:0061640 81 0.058
positive regulation of macromolecule metabolic process GO:0010604 405 0.057
dna repair GO:0006281 54 0.056
regulation of phosphorus metabolic process GO:0051174 210 0.054
organonitrogen compound metabolic process GO:1901564 318 0.054
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.054
columnar cuboidal epithelial cell development GO:0002066 249 0.053
small molecule metabolic process GO:0044281 305 0.053
cell proliferation GO:0008283 299 0.053
regulation of multicellular organismal development GO:2000026 414 0.052
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.051
regulation of double strand break repair GO:2000779 3 0.051
negative regulation of cellular component organization GO:0051129 108 0.050
regulation of cell cycle GO:0051726 291 0.050
death GO:0016265 284 0.049
chromatin modification GO:0016568 147 0.049
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.049
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.049
regulation of cellular component biogenesis GO:0044087 201 0.048
aromatic compound catabolic process GO:0019439 166 0.048
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.048
double strand break repair GO:0006302 26 0.048
negative regulation of multicellular organismal process GO:0051241 142 0.047
dna recombination GO:0006310 32 0.046
purine ribonucleoside catabolic process GO:0046130 112 0.046
axonogenesis GO:0007409 290 0.046
mitotic nuclear division GO:0007067 213 0.046
organonitrogen compound catabolic process GO:1901565 128 0.046
purine nucleoside metabolic process GO:0042278 127 0.046
purine containing compound metabolic process GO:0072521 155 0.045
protein modification process GO:0036211 438 0.045
regulation of mitotic cell cycle phase transition GO:1901990 130 0.044
establishment of localization in cell GO:0051649 402 0.044
negative regulation of cellular biosynthetic process GO:0031327 277 0.043
regulation of cell differentiation GO:0045595 302 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.041
cellular nitrogen compound catabolic process GO:0044270 165 0.041
heart development GO:0007507 82 0.040
negative regulation of transcription dna templated GO:0045892 237 0.040
regulation of neurogenesis GO:0050767 158 0.040
negative regulation of response to stimulus GO:0048585 258 0.039
regulation of mitotic cell cycle GO:0007346 190 0.039
nucleotide metabolic process GO:0009117 161 0.039
phosphorylation GO:0016310 294 0.038
purine containing compound catabolic process GO:0072523 112 0.038
meiotic cell cycle process GO:1903046 132 0.038
ribose phosphate metabolic process GO:0019693 145 0.038
macromolecule catabolic process GO:0009057 161 0.037
regulation of dna recombination GO:0000018 4 0.037
single organism biosynthetic process GO:0044711 206 0.037
carbohydrate derivative catabolic process GO:1901136 118 0.035
regulation of cell cycle process GO:0010564 181 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.035
cell cycle phase transition GO:0044770 140 0.035
modification dependent protein catabolic process GO:0019941 78 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.034
purine nucleoside triphosphate catabolic process GO:0009146 108 0.034
negative regulation of nucleic acid templated transcription GO:1903507 240 0.034
post embryonic appendage morphogenesis GO:0035120 385 0.034
nucleotide catabolic process GO:0009166 109 0.034
negative regulation of nervous system development GO:0051961 92 0.033
purine ribonucleoside metabolic process GO:0046128 127 0.033
protein phosphorylation GO:0006468 169 0.033
meiotic cell cycle GO:0051321 171 0.033
mitotic cell cycle phase transition GO:0044772 138 0.032
positive regulation of molecular function GO:0044093 136 0.032
axon development GO:0061564 297 0.032
ribonucleoside triphosphate metabolic process GO:0009199 119 0.032
negative regulation of biosynthetic process GO:0009890 277 0.031
protein catabolic process GO:0030163 101 0.031
protein dna complex assembly GO:0065004 63 0.031
chromatin remodeling GO:0006338 72 0.031
meiotic dna double strand break formation involved in reciprocal meiotic recombination GO:0010780 1 0.030
single organism catabolic process GO:0044712 228 0.030
nucleoside triphosphate metabolic process GO:0009141 120 0.030
ribonucleoside catabolic process GO:0042454 112 0.030
spindle organization GO:0007051 253 0.029
reciprocal meiotic recombination GO:0007131 19 0.029
response to organic substance GO:0010033 284 0.029
positive regulation of gene expression GO:0010628 290 0.029
double strand break repair via nonhomologous end joining GO:0006303 5 0.029
ubiquitin dependent protein catabolic process GO:0006511 78 0.029
regulation of gene silencing GO:0060968 63 0.029
positive regulation of biosynthetic process GO:0009891 316 0.028
establishment or maintenance of cell polarity GO:0007163 167 0.028
nucleoside catabolic process GO:0009164 112 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
transcription from rna polymerase ii promoter GO:0006366 368 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
mitotic cell cycle embryonic GO:0045448 38 0.028
developmental growth GO:0048589 280 0.028
apoptotic process GO:0006915 159 0.027
proteolysis GO:0006508 192 0.027
organophosphate metabolic process GO:0019637 195 0.027
spermatogenesis GO:0007283 200 0.026
camera type eye development GO:0043010 4 0.026
vesicle mediated transport GO:0016192 381 0.026
neurological system process GO:0050877 358 0.026
regulation of catabolic process GO:0009894 170 0.026
cellular protein modification process GO:0006464 438 0.026
segmentation GO:0035282 207 0.026
nucleobase containing small molecule metabolic process GO:0055086 174 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.026
mitotic spindle organization GO:0007052 220 0.025
purine nucleotide catabolic process GO:0006195 109 0.025
appendage morphogenesis GO:0035107 397 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.025
chromatin organization GO:0006325 207 0.024
nucleoside metabolic process GO:0009116 127 0.024
nucleoside phosphate catabolic process GO:1901292 110 0.024
ribonucleotide catabolic process GO:0009261 109 0.024
dna replication GO:0006260 48 0.024
appendage development GO:0048736 401 0.024
eye development GO:0001654 323 0.024
mrna metabolic process GO:0016071 124 0.023
regulation of chromosome organization GO:0033044 64 0.023
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.022
regulation of catalytic activity GO:0050790 185 0.022
negative regulation of mitotic cell cycle GO:0045930 109 0.022
cell division GO:0051301 248 0.022
centrosome organization GO:0051297 163 0.022
negative regulation of growth GO:0045926 84 0.022
central nervous system development GO:0007417 201 0.022
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.022
ribonucleoside metabolic process GO:0009119 127 0.022
negative regulation of organelle organization GO:0010639 56 0.022
dna duplex unwinding GO:0032508 16 0.022
response to abiotic stimulus GO:0009628 341 0.021
g1 s transition of mitotic cell cycle GO:0000082 31 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.021
gene silencing GO:0016458 138 0.021
gliogenesis GO:0042063 80 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
positive regulation of catalytic activity GO:0043085 118 0.020
purine ribonucleotide catabolic process GO:0009154 109 0.020
chromosome segregation GO:0007059 157 0.019
organelle assembly GO:0070925 198 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
positive regulation of transcription dna templated GO:0045893 266 0.019
mrna processing GO:0006397 104 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
regulation of organelle organization GO:0033043 196 0.019
oxoacid metabolic process GO:0043436 103 0.018
positive regulation of catabolic process GO:0009896 105 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.018
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.018
response to other organism GO:0051707 293 0.017
spindle assembly GO:0051225 80 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.017
negative regulation of developmental growth GO:0048640 64 0.017
body morphogenesis GO:0010171 2 0.017
macromolecular complex assembly GO:0065003 256 0.017
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.017
cellular protein localization GO:0034613 160 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
regulation of cell development GO:0060284 215 0.017
positive regulation of cellular biosynthetic process GO:0031328 316 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
blastoderm segmentation GO:0007350 159 0.017
phagocytosis GO:0006909 215 0.017
regulation of protein depolymerization GO:1901879 27 0.017
glycosyl compound metabolic process GO:1901657 127 0.016
regulation of cell division GO:0051302 72 0.016
spindle assembly involved in mitosis GO:0090307 50 0.016
regulation of hydrolase activity GO:0051336 97 0.016
dna damage checkpoint GO:0000077 78 0.016
response to bacterium GO:0009617 198 0.015
negative regulation of microtubule depolymerization GO:0007026 21 0.015
positive regulation of cell communication GO:0010647 250 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
establishment of organelle localization GO:0051656 122 0.015
cell cycle g1 s phase transition GO:0044843 31 0.015
regulation of synapse structure and activity GO:0050803 128 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.015
regulation of growth GO:0040008 233 0.015
response to biotic stimulus GO:0009607 294 0.015
guanosine containing compound catabolic process GO:1901069 74 0.015
compound eye morphogenesis GO:0001745 249 0.015
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
regulation of phosphorylation GO:0042325 147 0.015
positive regulation of nucleoside metabolic process GO:0045979 47 0.015
negative regulation of gene expression epigenetic GO:0045814 77 0.014
chromosome condensation GO:0030261 41 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
response to organonitrogen compound GO:0010243 75 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
response to oxygen containing compound GO:1901700 200 0.014
sister chromatid segregation GO:0000819 92 0.014
mitotic dna damage checkpoint GO:0044773 74 0.014
regulation of mitosis GO:0007088 56 0.014
organic substance transport GO:0071702 257 0.014
nucleoside monophosphate metabolic process GO:0009123 52 0.014
regulation of nucleotide catabolic process GO:0030811 48 0.014
sensory organ morphogenesis GO:0090596 260 0.013
chromosome organization GO:0051276 360 0.013
cellular macromolecule localization GO:0070727 220 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
regulation of cell death GO:0010941 173 0.013
nuclear dna replication GO:0033260 1 0.013
endocytosis GO:0006897 310 0.013
gtp catabolic process GO:0006184 72 0.013
mitotic g2 m transition checkpoint GO:0044818 70 0.013
cellular protein catabolic process GO:0044257 83 0.013
defense response to other organism GO:0098542 225 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
chromatin silencing GO:0006342 76 0.013
chromosome separation GO:0051304 42 0.013
response to endogenous stimulus GO:0009719 119 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
regulation of nucleoside metabolic process GO:0009118 50 0.013
regulation of purine nucleotide catabolic process GO:0033121 48 0.013
regulation of synapse organization GO:0050807 110 0.012
stem cell differentiation GO:0048863 117 0.012
dna biosynthetic process GO:0071897 24 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
growth GO:0040007 359 0.012
negative regulation of protein depolymerization GO:1901880 23 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
sex differentiation GO:0007548 81 0.012
protein localization GO:0008104 284 0.012
regulation of dna metabolic process GO:0051052 34 0.012
recombinational repair GO:0000725 13 0.012
synapse assembly GO:0007416 143 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.012
notch signaling pathway GO:0007219 120 0.012
positive regulation of gtpase activity GO:0043547 43 0.012
mitotic dna integrity checkpoint GO:0044774 75 0.012
regulation of synapse assembly GO:0051963 94 0.011
regulation of response to stress GO:0080134 200 0.011
homeostatic process GO:0042592 199 0.011
chromosome localization GO:0050000 20 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
wing disc morphogenesis GO:0007472 344 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
centrosome separation GO:0051299 20 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
meiotic chromosome segregation GO:0045132 59 0.011
intracellular protein transport GO:0006886 104 0.011
ribonucleoside monophosphate metabolic process GO:0009161 51 0.011
organophosphate catabolic process GO:0046434 112 0.010
mitotic chromosome condensation GO:0007076 22 0.010
dna replication initiation GO:0006270 6 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
programmed cell death GO:0012501 257 0.010
regulation of gtpase activity GO:0043087 44 0.010
cellular response to nitrogen compound GO:1901699 51 0.010
g2 dna damage checkpoint GO:0031572 69 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
immune system process GO:0002376 347 0.010
dna integrity checkpoint GO:0031570 81 0.010
regulation of glial cell differentiation GO:0045685 1 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010

Orc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
disease of anatomical entity DOID:7 0 0.018