Drosophila melanogaster

71 known processes

Prosalpha6T (Dmel_CG5648)

Proteasome alpha6T subunit

(Aliases: 5648,Dmel\CG5648,prosalpha6T,Alpha6T,CG5648)

Prosalpha6T biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sperm motility GO:0030317 12 0.756
male gamete generation GO:0048232 201 0.754
sperm individualization GO:0007291 48 0.677
spermatid differentiation GO:0048515 114 0.535
spermatid development GO:0007286 98 0.522
spermatogenesis GO:0007283 200 0.497
cellularization GO:0007349 90 0.366
copulation GO:0007620 26 0.262
insemination GO:0007320 22 0.239
cellular protein modification process GO:0006464 438 0.183
cell cell signaling involved in cell fate commitment GO:0045168 210 0.160
localization of cell GO:0051674 257 0.146
posttranscriptional regulation of gene expression GO:0010608 145 0.119
cell motility GO:0048870 251 0.103
mating GO:0007618 120 0.097
intracellular transport GO:0046907 228 0.084
spindle organization GO:0007051 253 0.082
microtubule bundle formation GO:0001578 27 0.079
protein modification process GO:0036211 438 0.075
cell projection assembly GO:0030031 94 0.075
lateral inhibition GO:0046331 206 0.073
cilium organization GO:0044782 41 0.068
axoneme assembly GO:0035082 18 0.067
proteolysis GO:0006508 192 0.066
Yeast
regulation of localization GO:0032879 275 0.064
establishment of localization in cell GO:0051649 402 0.064
programmed cell death GO:0012501 257 0.062
organelle assembly GO:0070925 198 0.059
negative regulation of response to stimulus GO:0048585 258 0.059
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.059
regulation of protein metabolic process GO:0051246 256 0.056
cellular component assembly involved in morphogenesis GO:0010927 151 0.055
regionalization GO:0003002 416 0.054
single organism cellular localization GO:1902580 180 0.054
response to temperature stimulus GO:0009266 106 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.050
regulation of response to stress GO:0080134 200 0.048
multi multicellular organism process GO:0044706 123 0.048
regulation of catalytic activity GO:0050790 185 0.047
microtubule based movement GO:0007018 51 0.047
chromosome organization GO:0051276 360 0.044
response to abiotic stimulus GO:0009628 341 0.044
death GO:0016265 284 0.044
wing disc morphogenesis GO:0007472 344 0.040
negative regulation of signal transduction GO:0009968 206 0.040
cell death GO:0008219 279 0.040
cytoplasmic transport GO:0016482 130 0.040
regulation of phosphate metabolic process GO:0019220 210 0.039
sperm competition GO:0046692 21 0.039
catabolic process GO:0009056 409 0.039
Yeast
single organism intracellular transport GO:1902582 207 0.039
negative regulation of cell communication GO:0010648 223 0.039
defense response GO:0006952 300 0.038
neurological system process GO:0050877 358 0.036
cellular catabolic process GO:0044248 372 0.035
Yeast
cation transmembrane transport GO:0098655 88 0.035
microtubule based transport GO:0010970 42 0.034
dephosphorylation GO:0016311 51 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.034
regulation of protein modification process GO:0031399 112 0.032
regulation of molecular function GO:0065009 217 0.032
cilium morphogenesis GO:0060271 39 0.032
organelle localization GO:0051640 148 0.032
response to external biotic stimulus GO:0043207 293 0.031
gene silencing GO:0016458 138 0.031
regulation of gene expression epigenetic GO:0040029 128 0.031
phagocytosis GO:0006909 215 0.031
regulation of cellular protein metabolic process GO:0032268 243 0.029
negative regulation of signaling GO:0023057 219 0.029
phosphorylation GO:0016310 294 0.029
mitochondrion organization GO:0007005 65 0.029
sleep GO:0030431 49 0.028
negative regulation of gene expression GO:0010629 387 0.028
organic substance transport GO:0071702 257 0.028
endocytosis GO:0006897 310 0.028
single organism biosynthetic process GO:0044711 206 0.028
appendage morphogenesis GO:0035107 397 0.027
cilium assembly GO:0042384 38 0.026
establishment or maintenance of cell polarity GO:0007163 167 0.026
imaginal disc derived appendage morphogenesis GO:0035114 395 0.026
response to biotic stimulus GO:0009607 294 0.025
eye photoreceptor cell differentiation GO:0001754 145 0.025
regulation of cell cycle GO:0051726 291 0.025
post embryonic appendage morphogenesis GO:0035120 385 0.025
imaginal disc derived appendage development GO:0048737 399 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
regulation of cellular component biogenesis GO:0044087 201 0.024
negative regulation of cellular biosynthetic process GO:0031327 277 0.024
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
regulation of phosphorus metabolic process GO:0051174 210 0.023
protein localization GO:0008104 284 0.023
rna localization GO:0006403 115 0.022
protein transport GO:0015031 155 0.022
small gtpase mediated signal transduction GO:0007264 88 0.022
cation transport GO:0006812 110 0.022
chromatin silencing GO:0006342 76 0.022
protein localization to organelle GO:0033365 82 0.022
response to wounding GO:0009611 94 0.022
single organism catabolic process GO:0044712 228 0.022
wound healing GO:0042060 75 0.021
regulation of defense response GO:0031347 102 0.021
regulation of immune response GO:0050776 118 0.021
cell division GO:0051301 248 0.021
endomembrane system organization GO:0010256 119 0.021
regulation of proteolysis GO:0030162 87 0.020
cell maturation GO:0048469 144 0.020
innate immune response GO:0045087 144 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
cellular macromolecule localization GO:0070727 220 0.020
response to oxidative stress GO:0006979 86 0.020
defense response to bacterium GO:0042742 178 0.020
vesicle mediated transport GO:0016192 381 0.020
response to starvation GO:0042594 97 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
embryo development ending in birth or egg hatching GO:0009792 152 0.019
nuclear division GO:0000280 332 0.019
single organism behavior GO:0044708 391 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
nucleocytoplasmic transport GO:0006913 72 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
protein complex assembly GO:0006461 200 0.019
axon cargo transport GO:0008088 29 0.018
organic substance catabolic process GO:1901575 308 0.018
Yeast
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
developmental growth GO:0048589 280 0.018
body morphogenesis GO:0010171 2 0.018
negative regulation of gene expression epigenetic GO:0045814 77 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
photoreceptor cell differentiation GO:0046530 170 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.017
cellular protein complex assembly GO:0043623 71 0.017
positive regulation of protein metabolic process GO:0051247 128 0.017
regulation of nervous system development GO:0051960 248 0.017
lipid localization GO:0010876 54 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
adult locomotory behavior GO:0008344 76 0.017
adult behavior GO:0030534 137 0.016
hematopoietic progenitor cell differentiation GO:0002244 1 0.016
macromolecule catabolic process GO:0009057 161 0.016
Yeast
negative regulation of transcription dna templated GO:0045892 237 0.016
tissue morphogenesis GO:0048729 297 0.016
homeostatic process GO:0042592 199 0.016
protein phosphorylation GO:0006468 169 0.016
sensory organ morphogenesis GO:0090596 260 0.016
positive regulation of molecular function GO:0044093 136 0.016
single organism membrane organization GO:0044802 93 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
eye morphogenesis GO:0048592 260 0.016
regulation of cellular localization GO:0060341 136 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
Yeast
nuclear transport GO:0051169 72 0.016
cellular macromolecular complex assembly GO:0034622 153 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
Yeast
regulation of immune system process GO:0002682 176 0.015
salivary gland development GO:0007431 162 0.015
nuclear import GO:0051170 51 0.015
autophagic cell death GO:0048102 83 0.015
centrosome organization GO:0051297 163 0.015
endoplasmic reticulum organization GO:0007029 13 0.015
dna integrity checkpoint GO:0031570 81 0.015
establishment of protein localization GO:0045184 163 0.015
regulation of catabolic process GO:0009894 170 0.015
developmental maturation GO:0021700 172 0.015
somatic muscle development GO:0007525 66 0.015
sterol homeostasis GO:0055092 4 0.015
transmembrane transport GO:0055085 139 0.014
carboxylic acid transport GO:0046942 18 0.014
regulation of intracellular transport GO:0032386 64 0.014
multicellular organismal aging GO:0010259 140 0.014
fertilization GO:0009566 26 0.014
growth GO:0040007 359 0.014
oxoacid metabolic process GO:0043436 103 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of protein import into nucleus GO:0042306 28 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
circadian sleep wake cycle GO:0042745 28 0.014
embryonic pattern specification GO:0009880 174 0.014
appendage development GO:0048736 401 0.014
macromolecular complex assembly GO:0065003 256 0.014
axis specification GO:0009798 167 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
serotonin uptake GO:0051610 1 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
organelle fission GO:0048285 340 0.013
posttranscriptional gene silencing by rna GO:0035194 45 0.013
cellular protein localization GO:0034613 160 0.013
regulation of lipid transport GO:0032368 3 0.013
ion transport GO:0006811 145 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
Yeast
single organism nuclear import GO:1902593 51 0.013
mitotic nuclear division GO:0007067 213 0.013
anion transport GO:0006820 41 0.013
ras protein signal transduction GO:0007265 88 0.013
establishment of protein localization to organelle GO:0072594 62 0.013
regulation of nucleocytoplasmic transport GO:0046822 35 0.013
protein targeting GO:0006605 64 0.013
rhythmic behavior GO:0007622 76 0.013
locomotory behavior GO:0007626 176 0.013
compound eye development GO:0048749 307 0.013
segmentation GO:0035282 207 0.013
response to bacterium GO:0009617 198 0.013
intracellular signal transduction GO:0035556 300 0.013
mitotic spindle organization GO:0007052 220 0.013
regulation of cellular response to stress GO:0080135 89 0.013
regulation of hydrolase activity GO:0051336 97 0.013
positive regulation of cell motility GO:2000147 3 0.013
protein targeting to nucleus GO:0044744 51 0.012
feeding behavior GO:0007631 50 0.012
protein complex biogenesis GO:0070271 201 0.012
positive regulation of proteolysis GO:0045862 52 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
positive regulation of cell death GO:0010942 69 0.012
positive regulation of peptidase activity GO:0010952 29 0.012
nitrogen compound transport GO:0071705 85 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
oocyte construction GO:0007308 112 0.012
forebrain development GO:0030900 2 0.012
regulation of multi organism process GO:0043900 131 0.012
oocyte microtubule cytoskeleton organization GO:0016325 35 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
regulation of protein localization GO:0032880 76 0.012
sensory perception GO:0007600 196 0.012
spindle assembly GO:0051225 80 0.012
circadian behavior GO:0048512 76 0.012
exocrine system development GO:0035272 162 0.012
aromatic compound catabolic process GO:0019439 166 0.012
imaginal disc pattern formation GO:0007447 91 0.012
response to lipopolysaccharide GO:0032496 4 0.012
carbohydrate metabolic process GO:0005975 82 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
immune system process GO:0002376 347 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
cell growth GO:0016049 108 0.012
anterior posterior pattern specification GO:0009952 136 0.012
mapk cascade GO:0000165 107 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
regulation of immune effector process GO:0002697 52 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
regulation of protein transport GO:0051223 57 0.011
protein catabolic process GO:0030163 101 0.011
Yeast
positive regulation of catalytic activity GO:0043085 118 0.011
oocyte differentiation GO:0009994 145 0.011
regulation of protein stability GO:0031647 43 0.011
regulation of cell death GO:0010941 173 0.011
oocyte development GO:0048599 124 0.011
negative regulation of developmental process GO:0051093 201 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
regulation of innate immune response GO:0045088 71 0.011
small molecule metabolic process GO:0044281 305 0.011
oocyte axis specification GO:0007309 108 0.011
dna damage checkpoint GO:0000077 78 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
jnk cascade GO:0007254 50 0.011
regulation of organelle organization GO:0033043 196 0.011
cell aging GO:0007569 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
protein processing GO:0016485 68 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
peptidyl amino acid modification GO:0018193 105 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
Yeast
cellular amino acid metabolic process GO:0006520 61 0.010
cognition GO:0050890 141 0.010
salivary gland cell autophagic cell death GO:0035071 83 0.010
positive regulation of signaling GO:0023056 243 0.010
sperm axoneme assembly GO:0007288 13 0.010
regulation of apoptotic process GO:0042981 130 0.010
intracellular protein transport GO:0006886 104 0.010
morphogenesis of an epithelium GO:0002009 276 0.010
positive regulation of catabolic process GO:0009896 105 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
wnt signaling pathway GO:0016055 98 0.010
organic acid metabolic process GO:0006082 103 0.010
positive regulation of endopeptidase activity GO:0010950 26 0.010
salivary gland morphogenesis GO:0007435 145 0.010
protein localization to nucleus GO:0034504 55 0.010
regulation of programmed cell death GO:0043067 152 0.010

Prosalpha6T disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.017
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
disease of metabolism DOID:0014667 0 0.013
acquired metabolic disease DOID:0060158 0 0.013
musculoskeletal system disease DOID:17 0 0.011