Drosophila melanogaster

41 known processes

tub (Dmel_CG10520)

tube

(Aliases: Dmel\CG10520,CG10520)

tub biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle structure development GO:0061061 224 0.836
small molecule metabolic process GO:0044281 305 0.497
embryo development ending in birth or egg hatching GO:0009792 152 0.351
muscle organ development GO:0007517 127 0.311
regulation of nervous system development GO:0051960 248 0.262
larval development GO:0002164 104 0.254
protein phosphorylation GO:0006468 169 0.241
muscle cell differentiation GO:0042692 103 0.219
negative regulation of signaling GO:0023057 219 0.217
regulation of defense response GO:0031347 102 0.196
dendrite morphogenesis GO:0048813 199 0.174
regulation of cell development GO:0060284 215 0.172
negative regulation of multicellular organismal process GO:0051241 142 0.162
regulation of cell differentiation GO:0045595 302 0.154
regulation of multicellular organismal development GO:2000026 414 0.151
defense response GO:0006952 300 0.150
positive regulation of molecular function GO:0044093 136 0.143
oxoacid metabolic process GO:0043436 103 0.136
humoral immune response GO:0006959 117 0.131
protein import GO:0017038 55 0.130
organic substance catabolic process GO:1901575 308 0.124
response to radiation GO:0009314 155 0.124
catabolic process GO:0009056 409 0.116
organonitrogen compound metabolic process GO:1901564 318 0.113
cellular catabolic process GO:0044248 372 0.112
regulation of cell projection organization GO:0031344 92 0.107
lipid localization GO:0010876 54 0.106
eye morphogenesis GO:0048592 260 0.104
negative regulation of cellular metabolic process GO:0031324 382 0.102
intracellular signal transduction GO:0035556 300 0.100
carbohydrate derivative metabolic process GO:1901135 217 0.099
negative regulation of rna metabolic process GO:0051253 251 0.097
synapse organization GO:0050808 196 0.096
mitotic cell cycle checkpoint GO:0007093 88 0.095
taxis GO:0042330 304 0.094
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.093
positive regulation of developmental process GO:0051094 143 0.092
cell motility GO:0048870 251 0.087
gene silencing GO:0016458 138 0.086
cellular response to dna damage stimulus GO:0006974 223 0.085
regulation of immune response GO:0050776 118 0.084
regulation of phosphate metabolic process GO:0019220 210 0.084
response to light stimulus GO:0009416 124 0.079
cell migration GO:0016477 238 0.078
regulation of notch signaling pathway GO:0008593 100 0.078
establishment of localization in cell GO:0051649 402 0.075
negative regulation of signal transduction GO:0009968 206 0.074
nucleoside phosphate metabolic process GO:0006753 162 0.074
nucleobase containing compound catabolic process GO:0034655 165 0.074
anatomical structure homeostasis GO:0060249 97 0.073
regulation of neurogenesis GO:0050767 158 0.071
phosphorylation GO:0016310 294 0.071
actin cytoskeleton organization GO:0030036 206 0.063
single organism biosynthetic process GO:0044711 206 0.063
regulation of cellular catabolic process GO:0031329 157 0.062
positive regulation of cellular biosynthetic process GO:0031328 316 0.061
positive regulation of cell migration GO:0030335 2 0.060
cell division GO:0051301 248 0.060
carbohydrate metabolic process GO:0005975 82 0.058
dendrite development GO:0016358 204 0.057
localization of cell GO:0051674 257 0.057
positive regulation of nucleic acid templated transcription GO:1903508 266 0.056
negative regulation of cell communication GO:0010648 223 0.056
cellular ketone metabolic process GO:0042180 24 0.056
tube morphogenesis GO:0035239 191 0.056
negative regulation of cellular biosynthetic process GO:0031327 277 0.055
positive regulation of nervous system development GO:0051962 69 0.055
regulation of neuron differentiation GO:0045664 103 0.054
cell maturation GO:0048469 144 0.053
gliogenesis GO:0042063 80 0.053
spermatid differentiation GO:0048515 114 0.050
carbohydrate derivative biosynthetic process GO:1901137 85 0.050
response to external biotic stimulus GO:0043207 293 0.049
positive regulation of intracellular signal transduction GO:1902533 116 0.049
nucleoside catabolic process GO:0009164 112 0.049
posttranscriptional gene silencing GO:0016441 46 0.049
positive regulation of immune system process GO:0002684 68 0.048
negative regulation of response to stimulus GO:0048585 258 0.048
regulation of localization GO:0032879 275 0.048
chemotaxis GO:0006935 249 0.048
neuron projection guidance GO:0097485 241 0.047
positive regulation of cell motility GO:2000147 3 0.046
small gtpase mediated signal transduction GO:0007264 88 0.046
regulation of catabolic process GO:0009894 170 0.046
negative regulation of developmental process GO:0051093 201 0.045
digestive system development GO:0055123 149 0.045
carbohydrate derivative catabolic process GO:1901136 118 0.045
regulation of response to stress GO:0080134 200 0.045
negative regulation of gene expression GO:0010629 387 0.045
regulation of cellular protein metabolic process GO:0032268 243 0.044
axon guidance GO:0007411 233 0.043
skeletal muscle organ development GO:0060538 48 0.042
cytoplasmic transport GO:0016482 130 0.042
vesicle mediated transport GO:0016192 381 0.042
tube development GO:0035295 244 0.042
single organism catabolic process GO:0044712 228 0.041
regulation of hydrolase activity GO:0051336 97 0.041
positive regulation of response to stimulus GO:0048584 323 0.040
regulation of map kinase activity GO:0043405 17 0.040
cellular protein modification process GO:0006464 438 0.040
immune system process GO:0002376 347 0.040
positive regulation of cell size GO:0045793 21 0.040
ribonucleotide metabolic process GO:0009259 145 0.039
nucleobase containing small molecule metabolic process GO:0055086 174 0.039
notch signaling pathway GO:0007219 120 0.039
activation of innate immune response GO:0002218 4 0.038
respiratory system development GO:0060541 213 0.038
immune effector process GO:0002252 98 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.038
purine containing compound metabolic process GO:0072521 155 0.038
organophosphate catabolic process GO:0046434 112 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
regulation of anatomical structure morphogenesis GO:0022603 242 0.037
regulation of phosphorylation GO:0042325 147 0.037
actin filament based process GO:0030029 220 0.036
open tracheal system development GO:0007424 204 0.036
biological adhesion GO:0022610 138 0.035
hematopoietic or lymphoid organ development GO:0048534 57 0.035
antimicrobial humoral response GO:0019730 99 0.035
positive regulation of catalytic activity GO:0043085 118 0.035
heterocycle catabolic process GO:0046700 166 0.035
salivary gland development GO:0007431 162 0.035
regulation of cellular amine metabolic process GO:0033238 3 0.034
regulation of protein metabolic process GO:0051246 256 0.034
regulation of intracellular signal transduction GO:1902531 236 0.034
regulation of purine nucleotide metabolic process GO:1900542 62 0.034
purine nucleoside catabolic process GO:0006152 112 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
synaptic transmission GO:0007268 288 0.033
negative regulation of biosynthetic process GO:0009890 277 0.033
response to other organism GO:0051707 293 0.033
regulation of cellular localization GO:0060341 136 0.033
positive regulation of phosphorus metabolic process GO:0010562 139 0.032
negative regulation of protein metabolic process GO:0051248 85 0.032
synapse assembly GO:0007416 143 0.032
somatic stem cell division GO:0048103 37 0.032
positive regulation of multicellular organismal process GO:0051240 143 0.032
aromatic compound catabolic process GO:0019439 166 0.031
response to wounding GO:0009611 94 0.031
striated muscle cell differentiation GO:0051146 90 0.031
ribonucleoside triphosphate metabolic process GO:0009199 119 0.030
developmental growth GO:0048589 280 0.030
spermatid development GO:0007286 98 0.030
cellular response to chemical stimulus GO:0070887 199 0.030
nucleoside triphosphate metabolic process GO:0009141 120 0.030
nucleoside metabolic process GO:0009116 127 0.030
regulation of phosphorus metabolic process GO:0051174 210 0.030
positive regulation of signal transduction GO:0009967 223 0.030
instar larval development GO:0002168 55 0.029
purine ribonucleoside catabolic process GO:0046130 112 0.029
immune response regulating signaling pathway GO:0002764 2 0.029
positive regulation of transcription dna templated GO:0045893 266 0.029
muscle attachment GO:0016203 36 0.028
developmental growth involved in morphogenesis GO:0060560 65 0.028
endocytosis GO:0006897 310 0.028
embryonic pattern specification GO:0009880 174 0.028
regulation of cell size GO:0008361 63 0.028
ribose phosphate metabolic process GO:0019693 145 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.028
regulation of synapse organization GO:0050807 110 0.027
regulation of developmental pigmentation GO:0048070 24 0.027
cell proliferation GO:0008283 299 0.027
cellular amino acid metabolic process GO:0006520 61 0.027
regulation of cellular component size GO:0032535 98 0.027
regulation of catalytic activity GO:0050790 185 0.027
regulation of immune effector process GO:0002697 52 0.026
protein complex assembly GO:0006461 200 0.026
immune response GO:0006955 246 0.026
regulation of cellular ketone metabolic process GO:0010565 3 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.025
regulation of cell adhesion GO:0030155 27 0.025
gene silencing by rna GO:0031047 57 0.025
negative regulation of cell differentiation GO:0045596 143 0.025
regulation of multi organism process GO:0043900 131 0.025
enzyme linked receptor protein signaling pathway GO:0007167 179 0.025
purine nucleoside metabolic process GO:0042278 127 0.024
ribonucleoside metabolic process GO:0009119 127 0.024
macromolecular complex assembly GO:0065003 256 0.024
response to biotic stimulus GO:0009607 294 0.023
protein catabolic process GO:0030163 101 0.023
negative regulation of transcription dna templated GO:0045892 237 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
regulation of cell substrate adhesion GO:0010810 2 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
regulation of response to external stimulus GO:0032101 115 0.023
growth GO:0040007 359 0.023
response to abiotic stimulus GO:0009628 341 0.023
cell activation GO:0001775 9 0.023
organonitrogen compound catabolic process GO:1901565 128 0.023
protein targeting to nucleus GO:0044744 51 0.022
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.022
neuromuscular junction development GO:0007528 149 0.022
negative regulation of cell death GO:0060548 81 0.022
response to nutrient levels GO:0031667 114 0.022
purine nucleotide metabolic process GO:0006163 146 0.022
organic acid metabolic process GO:0006082 103 0.022
jnk cascade GO:0007254 50 0.022
negative regulation of nervous system development GO:0051961 92 0.022
regulation of jnk cascade GO:0046328 40 0.021
nucleotide catabolic process GO:0009166 109 0.021
central nervous system development GO:0007417 201 0.021
positive regulation of cell communication GO:0010647 250 0.021
organic substance transport GO:0071702 257 0.021
peptidyl amino acid modification GO:0018193 105 0.021
negative regulation of translation GO:0017148 28 0.020
production of molecular mediator of immune response GO:0002440 46 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
retina development in camera type eye GO:0060041 4 0.020
regulation of organ morphogenesis GO:2000027 78 0.020
neurological system process GO:0050877 358 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
neuroblast division GO:0055057 35 0.019
regulation of protein modification process GO:0031399 112 0.019
developmental maturation GO:0021700 172 0.019
asymmetric neuroblast division GO:0055059 33 0.019
hematopoietic progenitor cell differentiation GO:0002244 1 0.019
response to starvation GO:0042594 97 0.018
regulation of vesicle mediated transport GO:0060627 59 0.018
maternal determination of anterior posterior axis embryo GO:0008358 74 0.018
response to extracellular stimulus GO:0009991 116 0.018
determination of bilateral symmetry GO:0009855 13 0.018
heart contraction GO:0060047 26 0.018
somatic muscle development GO:0007525 66 0.018
positive regulation of cell differentiation GO:0045597 64 0.018
stem cell division GO:0017145 69 0.018
purine nucleotide catabolic process GO:0006195 109 0.017
positive regulation of protein metabolic process GO:0051247 128 0.017
regulation of cytoplasmic transport GO:1903649 47 0.017
cellular protein catabolic process GO:0044257 83 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
regulation of molecular function GO:0065009 217 0.017
embryonic axis specification GO:0000578 107 0.017
cellular amine metabolic process GO:0044106 12 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.016
regulation of immune system process GO:0002682 176 0.016
axon development GO:0061564 297 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
rna processing GO:0006396 147 0.016
nuclear import GO:0051170 51 0.016
imaginal disc derived appendage morphogenesis GO:0035114 395 0.016
neuroblast proliferation GO:0007405 74 0.016
positive regulation of signaling GO:0023056 243 0.016
protein targeting GO:0006605 64 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
macromolecule catabolic process GO:0009057 161 0.016
tor signaling GO:0031929 32 0.016
secretion by cell GO:0032940 101 0.016
single organism carbohydrate metabolic process GO:0044723 72 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
nucleotide metabolic process GO:0009117 161 0.016
specification of symmetry GO:0009799 13 0.016
pole cell development GO:0007277 26 0.015
regulation of mapk cascade GO:0043408 92 0.015
embryonic heart tube development GO:0035050 22 0.015
ameboidal type cell migration GO:0001667 151 0.015
positive regulation of phosphorylation GO:0042327 87 0.015
regulation of embryonic development GO:0045995 68 0.015
embryonic organ development GO:0048568 50 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.015
regulation of anatomical structure size GO:0090066 163 0.015
protein complex biogenesis GO:0070271 201 0.015
asymmetric stem cell division GO:0098722 49 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
axis specification GO:0009798 167 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
cell aging GO:0007569 2 0.014
embryonic morphogenesis GO:0048598 206 0.014
appendage morphogenesis GO:0035107 397 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
single organismal cell cell adhesion GO:0016337 45 0.014
peptidyl tyrosine phosphorylation GO:0018108 24 0.014
organelle assembly GO:0070925 198 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
circulatory system process GO:0003013 37 0.014
regulation of synaptic transmission GO:0050804 69 0.014
kidney morphogenesis GO:0060993 3 0.014
amine metabolic process GO:0009308 12 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
appendage development GO:0048736 401 0.013
immune system development GO:0002520 57 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
proteolysis GO:0006508 192 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
protein localization GO:0008104 284 0.013
axonogenesis GO:0007409 290 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
posttranscriptional gene silencing by rna GO:0035194 45 0.013
rna localization GO:0006403 115 0.013
gland development GO:0048732 191 0.012
stem cell proliferation GO:0072089 88 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
protein import into nucleus GO:0006606 51 0.012
pole plasm mrna localization GO:0019094 49 0.012
neuronal stem cell division GO:0036445 35 0.012
asymmetric cell division GO:0008356 37 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
compound eye development GO:0048749 307 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
eye antennal disc development GO:0035214 60 0.012
positive regulation of kinase activity GO:0033674 25 0.012
regulation of programmed cell death GO:0043067 152 0.012
regulation of neuron death GO:1901214 26 0.012
negative regulation of phosphorus metabolic process GO:0010563 45 0.011
cellular protein localization GO:0034613 160 0.011
regulation of transport GO:0051049 181 0.011
protein modification process GO:0036211 438 0.011
wnt signaling pathway GO:0016055 98 0.011
terminal region determination GO:0007362 25 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
phagocytosis GO:0006909 215 0.011
protein localization to nucleus GO:0034504 55 0.011
immune response activating signal transduction GO:0002757 2 0.011
purine containing compound catabolic process GO:0072523 112 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.011
digestive tract development GO:0048565 149 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.011
camera type eye development GO:0043010 4 0.011
regulation of mrna 3 end processing GO:0031440 7 0.011
digestive tract morphogenesis GO:0048546 127 0.011
regulation of oocyte development GO:0060281 27 0.011
compound eye morphogenesis GO:0001745 249 0.011
hemopoiesis GO:0030097 46 0.011
positive regulation of catabolic process GO:0009896 105 0.010
connective tissue development GO:0061448 3 0.010
negative regulation of intracellular signal transduction GO:1902532 57 0.010
neuron recognition GO:0008038 101 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
cellular response to organic substance GO:0071310 132 0.010
cortical cytoskeleton organization GO:0030865 29 0.010
positive regulation of innate immune response GO:0045089 38 0.010
regulation of pole plasm oskar mrna localization GO:0007317 27 0.010
reproductive system development GO:0061458 74 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
positive regulation of cell adhesion GO:0045785 10 0.010
renal tubule development GO:0061326 64 0.010
mapk cascade GO:0000165 107 0.010
regulation of protein phosphorylation GO:0001932 64 0.010

tub disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
organ system cancer DOID:0050686 0 0.031