Drosophila melanogaster

2 known processes

Irp-1B (Dmel_CG6342)

Iron regulatory protein 1B

(Aliases: Dmel\CG6342,C-Acon,IRP-1,cAcon,IRP1,CG6342,144037_at,IRP-1B)

Irp-1B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular catabolic process GO:0044248 372 0.211
organic substance catabolic process GO:1901575 308 0.199
single organism catabolic process GO:0044712 228 0.192
catabolic process GO:0009056 409 0.190
small molecule metabolic process GO:0044281 305 0.181
Human
organic acid metabolic process GO:0006082 103 0.150
Human
lipid metabolic process GO:0006629 121 0.125
carboxylic acid metabolic process GO:0019752 92 0.087
Human
cellular lipid metabolic process GO:0044255 83 0.083
organonitrogen compound metabolic process GO:1901564 318 0.079
response to external biotic stimulus GO:0043207 293 0.078
acyl coa metabolic process GO:0006637 3 0.069
organophosphate metabolic process GO:0019637 195 0.067
lipid catabolic process GO:0016042 21 0.066
oxoacid metabolic process GO:0043436 103 0.065
Human
thioester metabolic process GO:0035383 3 0.064
single organism intracellular transport GO:1902582 207 0.062
single organism biosynthetic process GO:0044711 206 0.061
immune system process GO:0002376 347 0.056
monocarboxylic acid metabolic process GO:0032787 29 0.056
negative regulation of cellular metabolic process GO:0031324 382 0.055
cellular lipid catabolic process GO:0044242 16 0.054
cell proliferation GO:0008283 299 0.053
organic substance transport GO:0071702 257 0.051
appendage development GO:0048736 401 0.050
establishment of localization in cell GO:0051649 402 0.048
body morphogenesis GO:0010171 2 0.045
nucleoside phosphate metabolic process GO:0006753 162 0.041
fatty acid metabolic process GO:0006631 20 0.041
nucleobase containing small molecule metabolic process GO:0055086 174 0.040
positive regulation of macromolecule metabolic process GO:0010604 405 0.038
positive regulation of signaling GO:0023056 243 0.038
negative regulation of biosynthetic process GO:0009890 277 0.037
defense response GO:0006952 300 0.037
carbohydrate derivative metabolic process GO:1901135 217 0.037
carboxylic acid catabolic process GO:0046395 16 0.035
growth GO:0040007 359 0.033
telencephalon development GO:0021537 2 0.032
cell death GO:0008219 279 0.031
ion transport GO:0006811 145 0.031
intracellular transport GO:0046907 228 0.031
imaginal disc derived wing morphogenesis GO:0007476 337 0.031
neutral lipid biosynthetic process GO:0046460 2 0.030
macromolecular complex assembly GO:0065003 256 0.030
transcription from rna polymerase ii promoter GO:0006366 368 0.030
positive regulation of response to stimulus GO:0048584 323 0.029
carbohydrate metabolic process GO:0005975 82 0.028
negative regulation of gene expression GO:0010629 387 0.028
fatty acid catabolic process GO:0009062 9 0.027
cellular nitrogen compound catabolic process GO:0044270 165 0.027
response to bacterium GO:0009617 198 0.027
positive regulation of rna biosynthetic process GO:1902680 266 0.027
organic acid catabolic process GO:0016054 16 0.027
wing disc morphogenesis GO:0007472 344 0.026
organonitrogen compound catabolic process GO:1901565 128 0.026
defense response to bacterium GO:0042742 178 0.026
positive regulation of cell communication GO:0010647 250 0.026
response to other organism GO:0051707 293 0.026
purine containing compound metabolic process GO:0072521 155 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
response to biotic stimulus GO:0009607 294 0.025
cellular amino acid metabolic process GO:0006520 61 0.024
post embryonic appendage morphogenesis GO:0035120 385 0.024
ribonucleoside metabolic process GO:0009119 127 0.024
protein complex assembly GO:0006461 200 0.024
forebrain development GO:0030900 2 0.024
nucleoside metabolic process GO:0009116 127 0.024
oxidation reduction process GO:0055114 123 0.024
protein modification process GO:0036211 438 0.024
glycosyl compound metabolic process GO:1901657 127 0.024
maintenance of location GO:0051235 73 0.024
response to organic substance GO:0010033 284 0.023
Rat
hormone catabolic process GO:0042447 3 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
appendage morphogenesis GO:0035107 397 0.023
purine nucleotide metabolic process GO:0006163 146 0.023
tube development GO:0035295 244 0.023
Fly
mitotic spindle organization GO:0007052 220 0.023
nucleotide metabolic process GO:0009117 161 0.023
epithelial cell differentiation GO:0030855 322 0.023
purine ribonucleoside metabolic process GO:0046128 127 0.023
lipid storage GO:0019915 38 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.023
regulation of cell proliferation GO:0042127 163 0.022
purine nucleoside metabolic process GO:0042278 127 0.022
purine nucleoside monophosphate metabolic process GO:0009126 50 0.022
neurological system process GO:0050877 358 0.021
open tracheal system development GO:0007424 204 0.021
response to abiotic stimulus GO:0009628 341 0.021
Rat
regulation of immune system process GO:0002682 176 0.021
ribose phosphate metabolic process GO:0019693 145 0.021
cellular ketone metabolic process GO:0042180 24 0.021
fatty acid beta oxidation GO:0006635 6 0.021
monocarboxylic acid catabolic process GO:0072329 10 0.020
carbohydrate derivative biosynthetic process GO:1901137 85 0.020
heterocycle catabolic process GO:0046700 166 0.020
response to starvation GO:0042594 97 0.020
cellular protein modification process GO:0006464 438 0.020
negative regulation of cell communication GO:0010648 223 0.020
positive regulation of gene expression GO:0010628 290 0.020
immune response GO:0006955 246 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
regulation of protein metabolic process GO:0051246 256 0.019
programmed cell death GO:0012501 257 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
single organism carbohydrate metabolic process GO:0044723 72 0.019
organic hydroxy compound metabolic process GO:1901615 83 0.019
head development GO:0060322 135 0.019
defense response to other organism GO:0098542 225 0.019
defense response to gram negative bacterium GO:0050829 94 0.019
death GO:0016265 284 0.019
steroid metabolic process GO:0008202 20 0.019
central nervous system development GO:0007417 201 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
neutral lipid catabolic process GO:0046461 3 0.018
lipid modification GO:0030258 24 0.018
cellular hormone metabolic process GO:0034754 23 0.018
response to oxygen containing compound GO:1901700 200 0.018
Rat
phagocytosis GO:0006909 215 0.018
regulation of apoptotic process GO:0042981 130 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
cell migration GO:0016477 238 0.017
kidney epithelium development GO:0072073 3 0.017
small molecule catabolic process GO:0044282 21 0.017
regulation of immune response GO:0050776 118 0.017
negative regulation of signaling GO:0023057 219 0.017
spindle organization GO:0007051 253 0.017
regulation of localization GO:0032879 275 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
amine metabolic process GO:0009308 12 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
Rat
positive regulation of signal transduction GO:0009967 223 0.016
regionalization GO:0003002 416 0.016
cation transport GO:0006812 110 0.016
macromolecule catabolic process GO:0009057 161 0.016
anion homeostasis GO:0055081 3 0.016
small molecule biosynthetic process GO:0044283 37 0.016
ameboidal type cell migration GO:0001667 151 0.016
digestive system development GO:0055123 149 0.016
Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.016
transmembrane transport GO:0055085 139 0.016
regulation of hormone levels GO:0010817 40 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
taxis GO:0042330 304 0.015
negative regulation of signal transduction GO:0009968 206 0.015
apoptotic process GO:0006915 159 0.015
positive regulation of lipid metabolic process GO:0045834 4 0.015
cytoplasmic transport GO:0016482 130 0.015
protein complex biogenesis GO:0070271 201 0.015
regulation of response to stress GO:0080134 200 0.015
mrna metabolic process GO:0016071 124 0.015
cell motility GO:0048870 251 0.015
sesquiterpenoid metabolic process GO:0006714 3 0.014
response to copper ion GO:0046688 4 0.014
acylglycerol biosynthetic process GO:0046463 2 0.014
regulation of multi organism process GO:0043900 131 0.014
nucleoside monophosphate metabolic process GO:0009123 52 0.014
vesicle mediated transport GO:0016192 381 0.014
xenobiotic catabolic process GO:0042178 1 0.014
intracellular signal transduction GO:0035556 300 0.014
regulation of programmed cell death GO:0043067 152 0.014
single organism cellular localization GO:1902580 180 0.014
neuron projection guidance GO:0097485 241 0.014
developmental growth GO:0048589 280 0.014
inorganic ion transmembrane transport GO:0098660 73 0.014
ion transmembrane transport GO:0034220 122 0.014
spermatogenesis GO:0007283 200 0.013
kidney development GO:0001822 3 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
response to oxygen levels GO:0070482 59 0.013
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
gland development GO:0048732 191 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.013
lateral inhibition GO:0046331 206 0.013
response to organophosphorus GO:0046683 2 0.013
cellular response to organic substance GO:0071310 132 0.013
regulation of steroid metabolic process GO:0019218 2 0.013
cellular amine metabolic process GO:0044106 12 0.013
response to endogenous stimulus GO:0009719 119 0.013
protein transport GO:0015031 155 0.013
response to hexose GO:0009746 3 0.013
regulation of catabolic process GO:0009894 170 0.013
very long chain fatty acid metabolic process GO:0000038 4 0.012
sulfur compound metabolic process GO:0006790 59 0.012
regulation of cell death GO:0010941 173 0.012
acylglycerol catabolic process GO:0046464 3 0.012
response to alcohol GO:0097305 95 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
cellular protein localization GO:0034613 160 0.012
vitamin metabolic process GO:0006766 2 0.012
embryonic morphogenesis GO:0048598 206 0.012
Fly
imaginal disc derived appendage development GO:0048737 399 0.012
regulation of growth GO:0040008 233 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
response to lipopolysaccharide GO:0032496 4 0.012
chemotaxis GO:0006935 249 0.012
homeostatic process GO:0042592 199 0.012
Rat
negative regulation of rna metabolic process GO:0051253 251 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
epidermis development GO:0008544 65 0.012
brain development GO:0007420 120 0.011
respiratory system development GO:0060541 213 0.011
protein localization GO:0008104 284 0.011
ion homeostasis GO:0050801 55 0.011
Rat
multicellular organismal aging GO:0010259 140 0.011
localization of cell GO:0051674 257 0.011
response to nutrient levels GO:0031667 114 0.011
androgen metabolic process GO:0008209 1 0.011
lipid localization GO:0010876 54 0.011
response to organic cyclic compound GO:0014070 89 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
digestive tract development GO:0048565 149 0.011
Fly
ribonucleoside monophosphate metabolic process GO:0009161 51 0.011
cell cell junction organization GO:0045216 55 0.011
positive regulation of cell motility GO:2000147 3 0.011
cellular macromolecule localization GO:0070727 220 0.011
anion transport GO:0006820 41 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.010
regulation of transport GO:0051049 181 0.010
cellular amide metabolic process GO:0043603 80 0.010
cellular response to endogenous stimulus GO:0071495 80 0.010
biological adhesion GO:0022610 138 0.010
regulation of proteolysis GO:0030162 87 0.010
aromatic compound catabolic process GO:0019439 166 0.010
connective tissue development GO:0061448 3 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
negative regulation of transcription dna templated GO:0045892 237 0.010
rna processing GO:0006396 147 0.010
positive regulation of cellular biosynthetic process GO:0031328 316 0.010
hormone metabolic process GO:0042445 33 0.010

Irp-1B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.071
disease of anatomical entity DOID:7 0 0.035
inherited metabolic disorder DOID:655 0 0.025
nervous system disease DOID:863 0 0.022
carbohydrate metabolism disease DOID:0050013 0 0.019
glucose metabolism disease DOID:4194 0 0.019
acquired metabolic disease DOID:0060158 0 0.019
lipid metabolism disorder DOID:3146 0 0.014