Drosophila melanogaster

58 known processes

MED22 (Dmel_CG3034)

Mediator complex subunit 22

(Aliases: dMED24,Srb6/Surf5,Med22,clone 1.82,Med24,EG:BACR7A4.6,144358_at,Dmel\CG3034,CG3034,anon-EST:Liang-1.82,CG18830)

MED22 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 368 0.463
regulation of neuroblast proliferation GO:1902692 34 0.371
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.369
meiotic cell cycle GO:0051321 171 0.162
ovulation cycle GO:0042698 1 0.134
programmed cell death GO:0012501 257 0.110
meiotic nuclear division GO:0007126 151 0.099
hematopoietic stem cell differentiation GO:0060218 1 0.091
formation of a compartment boundary GO:0060288 4 0.087
cell division GO:0051301 248 0.080
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.072
positive regulation of nucleic acid templated transcription GO:1903508 266 0.058
cellular response to dna damage stimulus GO:0006974 223 0.044
regulation of cell differentiation GO:0045595 302 0.043
positive regulation of cellular biosynthetic process GO:0031328 316 0.043
neuroblast proliferation GO:0007405 74 0.035
negative regulation of eye photoreceptor cell development GO:0042480 3 0.035
larval development GO:0002164 104 0.033
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.033
vesicle mediated transport GO:0016192 381 0.031
neural precursor cell proliferation GO:0061351 75 0.031
cell death GO:0008219 279 0.031
negative regulation of rna biosynthetic process GO:1902679 240 0.027
positive regulation of neuron projection regeneration GO:0070572 3 0.026
cell chemotaxis involved in malpighian tubule morphogenesis GO:0061352 3 0.025
attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation GO:0051316 1 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
cytoplasmic sequestering of nf kappab GO:0007253 1 0.024
negative regulation of developmental process GO:0051093 201 0.024
negative regulation of transcription dna templated GO:0045892 237 0.023
cell motility GO:0048870 251 0.023
establishment or maintenance of polarity of larval imaginal disc epithelium GO:0016336 3 0.023
left right axis specification GO:0070986 1 0.022
regulation of cdc42 protein signal transduction GO:0032489 3 0.022
embryo development ending in birth or egg hatching GO:0009792 152 0.022
negative regulation of neural precursor cell proliferation GO:2000178 27 0.021
regulation of ruffle assembly GO:1900027 1 0.021
regulation of mitotic cell cycle phase transition GO:1901990 130 0.020
intermediate filament based process GO:0045103 1 0.019
gene silencing GO:0016458 138 0.019
regulation of neural precursor cell proliferation GO:2000177 35 0.019
septin cytoskeleton organization GO:0032185 1 0.018
mrna cis splicing via spliceosome GO:0045292 1 0.018
male gamete generation GO:0048232 201 0.018
stem cell proliferation GO:0072089 88 0.018
dna methylation on cytosine GO:0032776 1 0.017
small molecule metabolic process GO:0044281 305 0.017
cell proliferation GO:0008283 299 0.017
dna damage checkpoint GO:0000077 78 0.016
regulation of rac gtpase activity GO:0032314 1 0.016
negative regulation of developmental pigmentation GO:0048086 1 0.016
negative regulation of gene expression GO:0010629 387 0.016
muscle structure development GO:0061061 224 0.016
intermediate filament cytoskeleton organization GO:0045104 1 0.016
macromolecular complex assembly GO:0065003 256 0.016
nuclear division GO:0000280 332 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
dorsal closure leading edge cell differentiation GO:0046663 2 0.015
mrna splicing via spliceosome GO:0000398 73 0.015
positive regulation of epidermal growth factor activated receptor activity GO:0045741 1 0.015
response to oxygen containing compound GO:1901700 200 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
negative regulation of cell proliferation GO:0008285 69 0.014
membrane organization GO:0061024 112 0.014
dendrite morphogenesis GO:0048813 199 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
rna splicing via transesterification reactions GO:0000375 73 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.012
endocytosis GO:0006897 310 0.012
negative regulation of sister chromatid cohesion GO:0045875 1 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
meiotic nuclear envelope disassembly GO:0051078 2 0.012
icosanoid biosynthetic process GO:0046456 1 0.012
negative regulation of transcription factor import into nucleus GO:0042992 4 0.012
negative regulation of nucleoside metabolic process GO:0045978 1 0.012
positive regulation of binding GO:0051099 4 0.012
asymmetric neuroblast division resulting in ganglion mother cell formation GO:0055060 2 0.012
negative regulation of neuroblast proliferation GO:0007406 27 0.012
regulation of multicellular organismal development GO:2000026 414 0.011
regulation of phosphatase activity GO:0010921 3 0.011
dorsal vessel heart proper cell fate commitment GO:0035053 2 0.011
cell migration GO:0016477 238 0.011
spermatogenesis GO:0007283 200 0.011
exocrine system development GO:0035272 162 0.010
ribonucleoprotein complex disassembly GO:0032988 1 0.010
regulation of cell cycle GO:0051726 291 0.010

MED22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
female reproductive system disease DOID:229 0 0.018
ovarian disease DOID:1100 0 0.018
disease of anatomical entity DOID:7 0 0.018
reproductive system disease DOID:15 0 0.018
premature ovarian failure DOID:5426 0 0.018
respiratory system cancer DOID:0050615 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
benign neoplasm DOID:0060072 0 0.014
brachydactyly DOID:0050581 0 0.011
bone development disease DOID:0080006 0 0.011
bone disease DOID:0080001 0 0.011
dysostosis DOID:1934 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011