Drosophila melanogaster

57 known processes

Smg1 (Dmel_CG32743)

CG32743 gene product from transcript CG32743-RA

(Aliases: Dmel\CG32743,SMG1,anon-EST:Liang-1.24,smg1,dSmg1,rst(1a)cyr,CG4549,anon-WO0170980.133,Smg,CG32743,CG4555,clone 1.24)

Smg1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic vesicle transport GO:0048489 50 0.913
synaptic transmission GO:0007268 288 0.869
synaptic vesicle recycling GO:0036465 28 0.692
establishment of vesicle localization GO:0051650 51 0.652
neuromuscular synaptic transmission GO:0007274 67 0.643
synaptic vesicle endocytosis GO:0048488 28 0.590
vesicle localization GO:0051648 55 0.554
positive regulation of signaling GO:0023056 243 0.530
establishment of synaptic vesicle localization GO:0097480 50 0.518
cellular protein modification process GO:0006464 438 0.509
Human
intracellular signal transduction GO:0035556 300 0.385
regulation of catalytic activity GO:0050790 185 0.371
regulation of intracellular signal transduction GO:1902531 236 0.342
synapse organization GO:0050808 196 0.342
synaptic vesicle exocytosis GO:0016079 16 0.341
growth GO:0040007 359 0.341
organelle localization GO:0051640 148 0.331
g protein coupled receptor signaling pathway GO:0007186 136 0.326
synaptic vesicle localization GO:0097479 53 0.325
regulation of protein metabolic process GO:0051246 256 0.318
regulation of phosphorus metabolic process GO:0051174 210 0.317
cell death GO:0008219 279 0.313
phosphorylation GO:0016310 294 0.300
Human
purine ribonucleoside metabolic process GO:0046128 127 0.297
positive regulation of multicellular organismal process GO:0051240 143 0.288
nucleoside triphosphate catabolic process GO:0009143 108 0.286
positive regulation of gtpase activity GO:0043547 43 0.282
neurotransmitter secretion GO:0007269 35 0.279
mapk cascade GO:0000165 107 0.273
organic substance catabolic process GO:1901575 308 0.269
signal transduction by phosphorylation GO:0023014 107 0.259
protein modification process GO:0036211 438 0.258
Human
establishment of organelle localization GO:0051656 122 0.245
small molecule metabolic process GO:0044281 305 0.243
regulation of developmental growth GO:0048638 174 0.243
multi organism behavior GO:0051705 175 0.234
positive regulation of secretion GO:0051047 22 0.231
response to light stimulus GO:0009416 124 0.231
sensory perception of smell GO:0007608 80 0.227
regulation of multicellular organismal development GO:2000026 414 0.224
regulation of molecular function GO:0065009 217 0.224
epithelial cell migration GO:0010631 148 0.221
developmental growth GO:0048589 280 0.210
organonitrogen compound metabolic process GO:1901564 318 0.208
vesicle mediated transport GO:0016192 381 0.206
regulation of cellular component biogenesis GO:0044087 201 0.203
nucleotide catabolic process GO:0009166 109 0.200
ameboidal type cell migration GO:0001667 151 0.198
purine nucleotide catabolic process GO:0006195 109 0.194
positive regulation of cellular component organization GO:0051130 156 0.189
regulation of phosphate metabolic process GO:0019220 210 0.187
cellular catabolic process GO:0044248 372 0.185
ribonucleotide metabolic process GO:0009259 145 0.184
regulation of cellular protein metabolic process GO:0032268 243 0.182
exocytosis GO:0006887 28 0.179
positive regulation of macromolecule metabolic process GO:0010604 405 0.177
regulation of transport GO:0051049 181 0.174
positive regulation of nucleoside metabolic process GO:0045979 47 0.174
small gtpase mediated signal transduction GO:0007264 88 0.171
epithelium migration GO:0090132 148 0.170
establishment of localization in cell GO:0051649 402 0.168
death GO:0016265 284 0.162
regulation of synapse structure and activity GO:0050803 128 0.160
purine ribonucleotide catabolic process GO:0009154 109 0.155
secretion by cell GO:0032940 101 0.155
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.154
purine ribonucleoside catabolic process GO:0046130 112 0.152
regulation of localization GO:0032879 275 0.144
peptidyl amino acid modification GO:0018193 105 0.141
Human
regulation of gtp catabolic process GO:0033124 44 0.140
tissue migration GO:0090130 155 0.139
positive regulation of catalytic activity GO:0043085 118 0.139
single organism intracellular transport GO:1902582 207 0.138
signal release GO:0023061 49 0.137
immune response GO:0006955 246 0.137
positive regulation of phosphorylation GO:0042327 87 0.136
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.134
actin cytoskeleton organization GO:0030036 206 0.134
response to organic substance GO:0010033 284 0.133
secretion GO:0046903 109 0.133
axon development GO:0061564 297 0.131
locomotory behavior GO:0007626 176 0.131
enzyme linked receptor protein signaling pathway GO:0007167 179 0.131
glycosyl compound metabolic process GO:1901657 127 0.129
positive regulation of gtp catabolic process GO:0033126 43 0.129
positive regulation of phosphate metabolic process GO:0045937 139 0.129
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.128
regulation of programmed cell death GO:0043067 152 0.127
regulation of growth GO:0040008 233 0.126
positive regulation of cellular catabolic process GO:0031331 95 0.124
purine nucleoside triphosphate metabolic process GO:0009144 119 0.122
response to monosaccharide GO:0034284 4 0.122
forebrain development GO:0030900 2 0.122
neurotransmitter transport GO:0006836 37 0.118
regulation of cell death GO:0010941 173 0.118
positive regulation of cell communication GO:0010647 250 0.117
regulation of phosphorylation GO:0042325 147 0.116
actin filament based process GO:0030029 220 0.114
regulation of cell morphogenesis GO:0022604 163 0.113
regulation of anatomical structure morphogenesis GO:0022603 242 0.113
gtp metabolic process GO:0046039 72 0.113
catabolic process GO:0009056 409 0.112
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.112
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.112
chromatin modification GO:0016568 147 0.112
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.112
defense response GO:0006952 300 0.111
positive regulation of nucleotide catabolic process GO:0030813 46 0.110
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.109
chemotaxis GO:0006935 249 0.109
organonitrogen compound catabolic process GO:1901565 128 0.109
central nervous system development GO:0007417 201 0.105
intracellular transport GO:0046907 228 0.105
gtp catabolic process GO:0006184 72 0.105
cellular nitrogen compound catabolic process GO:0044270 165 0.104
programmed cell death GO:0012501 257 0.104
purine nucleoside triphosphate catabolic process GO:0009146 108 0.103
positive regulation of rna biosynthetic process GO:1902680 266 0.102
regulation of synapse organization GO:0050807 110 0.101
regulation of ras protein signal transduction GO:0046578 93 0.101
negative regulation of cell death GO:0060548 81 0.098
reproductive behavior GO:0019098 122 0.097
regulation of mapk cascade GO:0043408 92 0.096
regulation of map kinase activity GO:0043405 17 0.096
axonogenesis GO:0007409 290 0.095
positive regulation of response to stimulus GO:0048584 323 0.094
regulation of response to stress GO:0080134 200 0.093
activation of protein kinase activity GO:0032147 12 0.093
positive regulation of signal transduction GO:0009967 223 0.092
ribonucleoside triphosphate metabolic process GO:0009199 119 0.091
positive regulation of molecular function GO:0044093 136 0.091
cation transmembrane transport GO:0098655 88 0.091
nucleobase containing small molecule metabolic process GO:0055086 174 0.090
response to starvation GO:0042594 97 0.090
negative regulation of cellular metabolic process GO:0031324 382 0.090
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.090
guanosine containing compound catabolic process GO:1901069 74 0.090
response to toxic substance GO:0009636 22 0.090
protein phosphorylation GO:0006468 169 0.090
Human
regulation of vesicle mediated transport GO:0060627 59 0.089
positive regulation of phosphorus metabolic process GO:0010562 139 0.088
positive regulation of biosynthetic process GO:0009891 316 0.088
single organism catabolic process GO:0044712 228 0.088
immune system process GO:0002376 347 0.087
purine containing compound catabolic process GO:0072523 112 0.085
ribonucleoside catabolic process GO:0042454 112 0.085
nucleobase containing compound catabolic process GO:0034655 165 0.085
oxoacid metabolic process GO:0043436 103 0.085
negative regulation of cellular biosynthetic process GO:0031327 277 0.084
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.084
nucleoside catabolic process GO:0009164 112 0.084
ribonucleoside metabolic process GO:0009119 127 0.083
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.082
metal ion transport GO:0030001 74 0.081
negative regulation of cellular component organization GO:0051129 108 0.081
regulation of small gtpase mediated signal transduction GO:0051056 93 0.081
glycosyl compound catabolic process GO:1901658 112 0.081
cell motility GO:0048870 251 0.079
regulation of protein kinase activity GO:0045859 51 0.078
organophosphate metabolic process GO:0019637 195 0.078
Human
response to radiation GO:0009314 155 0.077
chromosome organization GO:0051276 360 0.077
heterocycle catabolic process GO:0046700 166 0.077
positive regulation of cellular component biogenesis GO:0044089 80 0.075
regulation of organelle organization GO:0033043 196 0.075
regulation of cell development GO:0060284 215 0.075
positive regulation of jun kinase activity GO:0043507 4 0.075
response to abiotic stimulus GO:0009628 341 0.074
sensory perception of chemical stimulus GO:0007606 116 0.073
cellular response to chemical stimulus GO:0070887 199 0.073
protein processing GO:0016485 68 0.073
regulation of transmembrane transport GO:0034762 27 0.073
detection of light stimulus GO:0009583 58 0.073
negative regulation of response to stimulus GO:0048585 258 0.073
cell growth GO:0016049 108 0.072
ras protein signal transduction GO:0007265 88 0.071
regulation of catabolic process GO:0009894 170 0.071
positive regulation of exocytosis GO:0045921 4 0.071
positive regulation of mapk cascade GO:0043410 63 0.070
cellularization GO:0007349 90 0.070
positive regulation of cellular protein metabolic process GO:0032270 118 0.069
synaptic transmission glutamatergic GO:0035249 7 0.069
ribonucleoside triphosphate catabolic process GO:0009203 108 0.069
multi multicellular organism process GO:0044706 123 0.068
regulation of response to external stimulus GO:0032101 115 0.067
single organism behavior GO:0044708 391 0.067
response to endogenous stimulus GO:0009719 119 0.067
vesicle organization GO:0016050 44 0.066
positive regulation of hydrolase activity GO:0051345 78 0.066
cell proliferation GO:0008283 299 0.066
covalent chromatin modification GO:0016569 106 0.065
cellular macromolecular complex assembly GO:0034622 153 0.065
cellular response to organic substance GO:0071310 132 0.065
endocytosis GO:0006897 310 0.065
mating GO:0007618 120 0.065
regulation of cellular response to stress GO:0080135 89 0.065
regulation of cell differentiation GO:0045595 302 0.065
positive regulation of protein kinase activity GO:0045860 25 0.064
regulation of immune system process GO:0002682 176 0.063
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.063
purine nucleotide metabolic process GO:0006163 146 0.062
peptidyl threonine phosphorylation GO:0018107 2 0.061
neurological system process GO:0050877 358 0.061
axon cargo transport GO:0008088 29 0.061
nucleoside phosphate catabolic process GO:1901292 110 0.060
synapse assembly GO:0007416 143 0.060
regulation of neurotransmitter levels GO:0001505 38 0.060
regulation of cellular ketone metabolic process GO:0010565 3 0.059
regulation of cellular localization GO:0060341 136 0.059
purine ribonucleotide metabolic process GO:0009150 145 0.059
nucleoside triphosphate metabolic process GO:0009141 120 0.059
regulation of anatomical structure size GO:0090066 163 0.058
endomembrane system organization GO:0010256 119 0.057
regulation of epithelial cell proliferation GO:0050678 4 0.057
actin filament organization GO:0007015 126 0.057
regulation of neuron projection development GO:0010975 69 0.057
regulation of nucleotide metabolic process GO:0006140 62 0.057
carboxylic acid metabolic process GO:0019752 92 0.057
regulation of purine nucleotide catabolic process GO:0033121 48 0.056
regulation of nucleoside metabolic process GO:0009118 50 0.056
single organism membrane organization GO:0044802 93 0.056
protein catabolic process GO:0030163 101 0.054
protein complex biogenesis GO:0070271 201 0.053
regulation of nucleotide catabolic process GO:0030811 48 0.053
cation homeostasis GO:0055080 51 0.053
response to hydrogen peroxide GO:0042542 11 0.053
transmembrane transport GO:0055085 139 0.053
response to reactive oxygen species GO:0000302 24 0.053
regulation of cellular amine metabolic process GO:0033238 3 0.052
embryonic development via the syncytial blastoderm GO:0001700 148 0.052
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.052
organic substance transport GO:0071702 257 0.052
protein kinase a signaling GO:0010737 2 0.052
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.052
regionalization GO:0003002 416 0.051
adult locomotory behavior GO:0008344 76 0.051
negative regulation of signal transduction GO:0009968 206 0.051
regulation of secretion by cell GO:1903530 39 0.050
developmental cell growth GO:0048588 52 0.050
positive regulation of intracellular signal transduction GO:1902533 116 0.050
establishment of protein localization GO:0045184 163 0.050
ribonucleotide catabolic process GO:0009261 109 0.050
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.050
cellular response to starvation GO:0009267 61 0.049
protein maturation GO:0051604 71 0.049
nucleoside metabolic process GO:0009116 127 0.048
regulation of protein phosphorylation GO:0001932 64 0.048
autophagy GO:0006914 108 0.048
multi organism reproductive behavior GO:0044705 121 0.048
response to nutrient levels GO:0031667 114 0.047
actin filament based movement GO:0030048 26 0.047
small molecule biosynthetic process GO:0044283 37 0.047
neuron neuron synaptic transmission GO:0007270 14 0.046
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.046
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.045
head development GO:0060322 135 0.045
regulation of membrane potential GO:0042391 35 0.045
endosomal transport GO:0016197 44 0.045
positive regulation of rna metabolic process GO:0051254 271 0.045
nucleotide metabolic process GO:0009117 161 0.044
negative regulation of transcription dna templated GO:0045892 237 0.044
cell migration GO:0016477 238 0.044
response to oxidative stress GO:0006979 86 0.044
regulation of protein complex assembly GO:0043254 42 0.044
membrane depolarization GO:0051899 4 0.043
regulation of protein modification process GO:0031399 112 0.043
single organism biosynthetic process GO:0044711 206 0.043
localization of cell GO:0051674 257 0.043
proteolysis GO:0006508 192 0.042
regulation of protein serine threonine kinase activity GO:0071900 25 0.042
negative regulation of protein metabolic process GO:0051248 85 0.042
organic acid metabolic process GO:0006082 103 0.042
response to oxygen containing compound GO:1901700 200 0.042
regulation of cell cycle g1 s phase transition GO:1902806 23 0.042
adult behavior GO:0030534 137 0.042
cellular ion homeostasis GO:0006873 39 0.041
positive regulation of ras gtpase activity GO:0032320 36 0.041
negative regulation of biosynthetic process GO:0009890 277 0.040
response to alkaloid GO:0043279 26 0.040
regulation of cell projection organization GO:0031344 92 0.040
divalent inorganic cation transport GO:0072511 30 0.040
organophosphate catabolic process GO:0046434 112 0.040
macromolecular complex assembly GO:0065003 256 0.040
neuromuscular junction development GO:0007528 149 0.040
regulation of multi organism process GO:0043900 131 0.040
cellular amino acid metabolic process GO:0006520 61 0.039
stress activated mapk cascade GO:0051403 52 0.039
carbohydrate derivative catabolic process GO:1901136 118 0.039
purine containing compound metabolic process GO:0072521 155 0.039
response to growth factor GO:0070848 31 0.039
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.038
ion transport GO:0006811 145 0.037
guanosine containing compound metabolic process GO:1901068 74 0.037
regulation of neurogenesis GO:0050767 158 0.037
regulation of cellular amino acid metabolic process GO:0006521 0 0.037
purine nucleoside metabolic process GO:0042278 127 0.037
regulation of synapse assembly GO:0051963 94 0.037
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.037
meiotic nuclear division GO:0007126 151 0.036
organic cyclic compound catabolic process GO:1901361 168 0.036
regulation of nervous system development GO:0051960 248 0.036
regulation of gtpase activity GO:0043087 44 0.036
positive regulation of synaptic transmission GO:0050806 15 0.036
regulation of locomotion GO:0040012 42 0.036
regulation of proteolysis GO:0030162 87 0.036
response to organic cyclic compound GO:0014070 89 0.036
positive regulation of cell migration GO:0030335 2 0.036
establishment of cell polarity GO:0030010 40 0.036
positive regulation of transcription dna templated GO:0045893 266 0.036
positive regulation of cell motility GO:2000147 3 0.036
regulation of receptor activity GO:0010469 10 0.035
purine nucleoside catabolic process GO:0006152 112 0.035
protein ubiquitination GO:0016567 70 0.035
flight behavior GO:0007629 26 0.035
regulation of kinase activity GO:0043549 53 0.035
cellular response to light stimulus GO:0071482 37 0.034
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.034
cellular lipid metabolic process GO:0044255 83 0.034
Human
feeding behavior GO:0007631 50 0.034
negative regulation of signaling GO:0023057 219 0.033
cation transport GO:0006812 110 0.033
detection of stimulus involved in sensory perception GO:0050906 92 0.033
cellular ketone metabolic process GO:0042180 24 0.033
regulation of cytoskeleton organization GO:0051493 89 0.033
calcium ion transport GO:0006816 24 0.033
carbohydrate derivative metabolic process GO:1901135 217 0.033
regulation of synaptic vesicle exocytosis GO:2000300 3 0.033
heart process GO:0003015 37 0.032
amine metabolic process GO:0009308 12 0.032
cellular amine metabolic process GO:0044106 12 0.032
protein complex assembly GO:0006461 200 0.032
regulation of ras gtpase activity GO:0032318 38 0.032
cell division GO:0051301 248 0.032
neuron projection guidance GO:0097485 241 0.031
transcription from rna polymerase ii promoter GO:0006366 368 0.031
membrane organization GO:0061024 112 0.031
post golgi vesicle mediated transport GO:0006892 11 0.031
positive regulation of developmental growth GO:0048639 62 0.030
positive regulation of cell differentiation GO:0045597 64 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.030
jnk cascade GO:0007254 50 0.030
compound eye morphogenesis GO:0001745 249 0.030
regulation of cellular catabolic process GO:0031329 157 0.030
mitotic cell cycle phase transition GO:0044772 138 0.029
learning GO:0007612 75 0.029
negative regulation of programmed cell death GO:0043069 72 0.029
regulation of hydrolase activity GO:0051336 97 0.029
protein localization GO:0008104 284 0.029
multicellular organismal reproductive behavior GO:0033057 110 0.029
plasma membrane organization GO:0007009 26 0.028
protein modification by small protein conjugation or removal GO:0070647 106 0.028
detection of chemical stimulus GO:0009593 93 0.028
ion transmembrane transport GO:0034220 122 0.027
nucleoside phosphate metabolic process GO:0006753 162 0.027
positive regulation of protein complex assembly GO:0031334 22 0.027
organelle assembly GO:0070925 198 0.027
negative regulation of rna metabolic process GO:0051253 251 0.027
eye morphogenesis GO:0048592 260 0.027
cellular macromolecule catabolic process GO:0044265 136 0.027
ketone biosynthetic process GO:0042181 16 0.027
regulation of secretion GO:0051046 44 0.027
positive regulation of gene expression GO:0010628 290 0.027
telencephalon development GO:0021537 2 0.026
cellular response to extracellular stimulus GO:0031668 64 0.026
microtubule based movement GO:0007018 51 0.026
negative regulation of cell communication GO:0010648 223 0.026
cell adhesion GO:0007155 136 0.026
regulation of steroid metabolic process GO:0019218 2 0.025
energy derivation by oxidation of organic compounds GO:0015980 32 0.025
learning or memory GO:0007611 141 0.025
cellular macromolecule localization GO:0070727 220 0.025
metal ion homeostasis GO:0055065 44 0.025
cellular calcium ion homeostasis GO:0006874 21 0.025
connective tissue development GO:0061448 3 0.024
phagocytosis GO:0006909 215 0.024
negative regulation of gene expression GO:0010629 387 0.024
tissue morphogenesis GO:0048729 297 0.024
tricarboxylic acid metabolic process GO:0072350 1 0.024
regulation of cell proliferation GO:0042127 163 0.024
regulation of cell substrate adhesion GO:0010810 2 0.024
positive regulation of synapse assembly GO:0051965 29 0.024
positive regulation of nervous system development GO:0051962 69 0.024
single organism cellular localization GO:1902580 180 0.024
positive regulation of catabolic process GO:0009896 105 0.024
regulation of apoptotic process GO:0042981 130 0.024
pathway restricted smad protein phosphorylation GO:0060389 1 0.024
regulation of protein complex disassembly GO:0043244 29 0.024
modification dependent macromolecule catabolic process GO:0043632 79 0.024
response to extracellular stimulus GO:0009991 116 0.024
negative regulation of developmental process GO:0051093 201 0.024
regulation of ion transmembrane transport GO:0034765 27 0.023
aromatic compound catabolic process GO:0019439 166 0.023
ribose phosphate metabolic process GO:0019693 145 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
developmental growth involved in morphogenesis GO:0060560 65 0.023
negative regulation of intracellular signal transduction GO:1902532 57 0.023
response to paraquat GO:1901562 4 0.023
response to biotic stimulus GO:0009607 294 0.023
terminal button organization GO:0072553 19 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
establishment or maintenance of cell polarity GO:0007163 167 0.022
negative regulation of phosphorus metabolic process GO:0010563 45 0.022
microtubule based transport GO:0010970 42 0.022
homeostatic process GO:0042592 199 0.022
negative regulation of multicellular organismal process GO:0051241 142 0.022
regulation of synaptic vesicle transport GO:1902803 10 0.022
substrate adhesion dependent cell spreading GO:0034446 2 0.022
regulation of blood circulation GO:1903522 21 0.022
ovarian follicle cell development GO:0030707 248 0.022
apoptotic process GO:0006915 159 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
cellular response to endogenous stimulus GO:0071495 80 0.022
tube development GO:0035295 244 0.022
cellular response to oxygen containing compound GO:1901701 79 0.022
cytoplasmic transport GO:0016482 130 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.022
regulation of terminal button organization GO:2000331 11 0.021
rna processing GO:0006396 147 0.021
female gonad development GO:0008585 12 0.021
cognition GO:0050890 141 0.021
peptidyl lysine modification GO:0018205 57 0.021
larval development GO:0002164 104 0.021
cellular protein catabolic process GO:0044257 83 0.021
macroautophagy GO:0016236 42 0.021
eye development GO:0001654 323 0.021
positive regulation of secretion by cell GO:1903532 20 0.021
response to bacterium GO:0009617 198 0.020
regulation of purine nucleotide metabolic process GO:1900542 62 0.020
immune effector process GO:0002252 98 0.020
negative regulation of nucleic acid templated transcription GO:1903507 240 0.020
regulation of cell cycle GO:0051726 291 0.020
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.020
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
regulation of neuromuscular synaptic transmission GO:1900073 15 0.020
regulation of tube size GO:0035150 46 0.020
synaptic vesicle priming GO:0016082 1 0.020
stress activated protein kinase signaling cascade GO:0031098 55 0.020
cellular response to nutrient levels GO:0031669 62 0.019
cellular response to external stimulus GO:0071496 66 0.019
protein modification by small protein conjugation GO:0032446 79 0.019
compound eye development GO:0048749 307 0.019
axon extension GO:0048675 32 0.019
defense response to other organism GO:0098542 225 0.019
organ growth GO:0035265 56 0.019
positive regulation of transport GO:0051050 92 0.019
regulation of filopodium assembly GO:0051489 24 0.019
axon guidance GO:0007411 233 0.019
filopodium assembly GO:0046847 33 0.019
cellular protein localization GO:0034613 160 0.019
detection of visible light GO:0009584 38 0.019
lipid localization GO:0010876 54 0.019
cellular chemical homeostasis GO:0055082 40 0.019
developmental programmed cell death GO:0010623 138 0.019
response to hormone GO:0009725 45 0.018
phototransduction GO:0007602 52 0.018
organelle fusion GO:0048284 46 0.018
response to hexose GO:0009746 3 0.018
sensory perception GO:0007600 196 0.018
maintenance of presynaptic active zone structure GO:0048790 8 0.018
innate immune response GO:0045087 144 0.018
epithelial cell development GO:0002064 274 0.018
oocyte differentiation GO:0009994 145 0.018
positive regulation of cell development GO:0010720 61 0.018
activation of jun kinase activity GO:0007257 3 0.018
cellular cation homeostasis GO:0030003 38 0.018
response to inorganic substance GO:0010035 44 0.018
positive regulation of nucleotide metabolic process GO:0045981 55 0.018
divalent metal ion transport GO:0070838 26 0.018
regulation of neuron differentiation GO:0045664 103 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
dna metabolic process GO:0006259 227 0.017
developmental maturation GO:0021700 172 0.017
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.017
regulation of cell shape GO:0008360 113 0.017
protein transport GO:0015031 155 0.017
organic hydroxy compound metabolic process GO:1901615 83 0.017
posttranscriptional regulation of gene expression GO:0010608 145 0.017
neuroblast proliferation GO:0007405 74 0.017
cell cell adhesion GO:0098609 26 0.017
positive regulation of cell proliferation GO:0008284 47 0.017
regulation of transferase activity GO:0051338 58 0.017
cellular response to growth factor stimulus GO:0071363 30 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
rhythmic excitation GO:0043179 1 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.017
oxidation reduction process GO:0055114 123 0.017
negative regulation of growth GO:0045926 84 0.016
golgi vesicle transport GO:0048193 27 0.016
cellular divalent inorganic cation homeostasis GO:0072503 23 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016

Smg1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.088
artery disease DOID:0050828 0 0.047
vascular disease DOID:178 0 0.047
cardiovascular system disease DOID:1287 0 0.047
nervous system disease DOID:863 0 0.027
disease of cellular proliferation DOID:14566 0 0.020