Drosophila melanogaster

37 known processes

l(1)G0148 (Dmel_CG32742)

lethal (1) G0148

(Aliases: Dmel\CG32742,l(1)G0149,anon-WO03040301.250,cdc7-related,CG8655,CG8656,CG32742,CT25076,l(1)G0461)

l(1)G0148 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transcription dna templated GO:0045893 266 0.189
central nervous system development GO:0007417 201 0.178
vesicle mediated transport GO:0016192 381 0.135
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.131
Human
positive regulation of cellular biosynthetic process GO:0031328 316 0.106
Human
regulation of cellular component biogenesis GO:0044087 201 0.098
positive regulation of rna metabolic process GO:0051254 271 0.095
female meiotic division GO:0007143 70 0.091
organelle assembly GO:0070925 198 0.083
negative regulation of cellular biosynthetic process GO:0031327 277 0.076
positive regulation of gene expression GO:0010628 290 0.074
body morphogenesis GO:0010171 2 0.071
positive regulation of biosynthetic process GO:0009891 316 0.066
Human
protein modification by small protein conjugation or removal GO:0070647 106 0.065
transcription from rna polymerase ii promoter GO:0006366 368 0.064
post embryonic appendage morphogenesis GO:0035120 385 0.064
actin cytoskeleton organization GO:0030036 206 0.064
imaginal disc derived appendage morphogenesis GO:0035114 395 0.063
regulation of catabolic process GO:0009894 170 0.062
nuclear division GO:0000280 332 0.059
ubiquitin dependent protein catabolic process GO:0006511 78 0.059
macromolecule catabolic process GO:0009057 161 0.058
mitotic cell cycle phase transition GO:0044772 138 0.054
Human
positive regulation of nucleic acid templated transcription GO:1903508 266 0.054
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.053
respiratory system development GO:0060541 213 0.050
appendage development GO:0048736 401 0.050
gene silencing GO:0016458 138 0.046
cellular amino acid metabolic process GO:0006520 61 0.046
catabolic process GO:0009056 409 0.043
forebrain development GO:0030900 2 0.043
establishment of organelle localization GO:0051656 122 0.042
programmed cell death GO:0012501 257 0.042
appendage morphogenesis GO:0035107 397 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.041
Human
camera type eye development GO:0043010 4 0.040
negative regulation of developmental process GO:0051093 201 0.038
positive regulation of response to stimulus GO:0048584 323 0.038
regulation of cell cycle process GO:0010564 181 0.038
Human
imaginal disc derived appendage development GO:0048737 399 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.036
Human
regulation of organelle organization GO:0033043 196 0.034
leg disc development GO:0035218 92 0.034
endocytosis GO:0006897 310 0.034
Fly
cellular protein catabolic process GO:0044257 83 0.033
imaginal disc derived leg morphogenesis GO:0007480 80 0.033
negative regulation of signal transduction GO:0009968 206 0.032
regionalization GO:0003002 416 0.032
establishment of synaptic vesicle localization GO:0097480 50 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.031
cellularization GO:0007349 90 0.031
organelle fission GO:0048285 340 0.030
cellular catabolic process GO:0044248 372 0.030
myofibril assembly GO:0030239 36 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.029
carboxylic acid metabolic process GO:0019752 92 0.029
cellular macromolecular complex assembly GO:0034622 153 0.029
response to abiotic stimulus GO:0009628 341 0.029
cellular protein modification process GO:0006464 438 0.029
Human
leg disc morphogenesis GO:0007478 80 0.029
lateral inhibition GO:0046331 206 0.028
regulation of cellular ketone metabolic process GO:0010565 3 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
extrinsic apoptotic signaling pathway GO:0097191 1 0.026
telencephalon development GO:0021537 2 0.026
microtubule organizing center organization GO:0031023 168 0.026
negative regulation of nervous system development GO:0051961 92 0.025
mitotic sister chromatid separation GO:0051306 30 0.025
small molecule metabolic process GO:0044281 305 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.024
cell death GO:0008219 279 0.024
negative regulation of gene expression GO:0010629 387 0.024
macromolecular complex assembly GO:0065003 256 0.024
regulation of cytoskeleton organization GO:0051493 89 0.024
synaptic vesicle recycling GO:0036465 28 0.024
protein modification process GO:0036211 438 0.024
Human
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.024
ribonucleoside metabolic process GO:0009119 127 0.024
eye photoreceptor cell differentiation GO:0001754 145 0.024
histone modification GO:0016570 106 0.024
cellular macromolecule catabolic process GO:0044265 136 0.022
maintenance of location GO:0051235 73 0.022
positive regulation of chromosome segregation GO:0051984 10 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
eye morphogenesis GO:0048592 260 0.022
histone h4 k12 acetylation GO:0043983 2 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
eye development GO:0001654 323 0.022
positive regulation of cellular component organization GO:0051130 156 0.022
positive regulation of signaling GO:0023056 243 0.021
peptidyl lysine modification GO:0018205 57 0.021
protein modification by small protein removal GO:0070646 28 0.021
sensory organ morphogenesis GO:0090596 260 0.021
lipid metabolic process GO:0006629 121 0.021
cell projection assembly GO:0030031 94 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
organic substance catabolic process GO:1901575 308 0.021
embryonic morphogenesis GO:0048598 206 0.021
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
chromosome separation GO:0051304 42 0.021
segmentation GO:0035282 207 0.021
establishment of localization in cell GO:0051649 402 0.021
nucleotide metabolic process GO:0009117 161 0.020
photoreceptor cell differentiation GO:0046530 170 0.020
protein localization GO:0008104 284 0.020
regulation of protein metabolic process GO:0051246 256 0.020
centrosome organization GO:0051297 163 0.020
response to organic substance GO:0010033 284 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
Human
developmental growth GO:0048589 280 0.020
glycerolipid metabolic process GO:0046486 34 0.020
retina development in camera type eye GO:0060041 4 0.019
proteasomal protein catabolic process GO:0010498 59 0.019
regulation of cellular response to stress GO:0080135 89 0.019
regulation of protein complex assembly GO:0043254 42 0.019
meiotic cell cycle GO:0051321 171 0.019
cellular amine metabolic process GO:0044106 12 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
chromatin remodeling GO:0006338 72 0.019
modification dependent macromolecule catabolic process GO:0043632 79 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
hematopoietic progenitor cell differentiation GO:0002244 1 0.018
chromatin modification GO:0016568 147 0.018
protein dna complex subunit organization GO:0071824 86 0.018
proteolysis GO:0006508 192 0.018
actomyosin structure organization GO:0031032 56 0.018
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.018
head development GO:0060322 135 0.018
male gamete generation GO:0048232 201 0.018
actin filament based process GO:0030029 220 0.018
intracellular signal transduction GO:0035556 300 0.018
response to lipopolysaccharide GO:0032496 4 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
epiboly involved in wound healing GO:0090505 2 0.018
growth GO:0040007 359 0.018
cellular protein complex assembly GO:0043623 71 0.018
tissue death GO:0016271 102 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.017
organic acid metabolic process GO:0006082 103 0.017
death GO:0016265 284 0.017
eye photoreceptor cell development GO:0042462 81 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
negative regulation of rna metabolic process GO:0051253 251 0.017
organophosphate metabolic process GO:0019637 195 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
compound eye development GO:0048749 307 0.016
oxoacid metabolic process GO:0043436 103 0.016
cell maturation GO:0048469 144 0.016
regulation of catalytic activity GO:0050790 185 0.016
wound healing GO:0042060 75 0.015
nucleus organization GO:0006997 45 0.015
protein deubiquitination GO:0016579 17 0.015
protein polymerization GO:0051258 42 0.015
developmental programmed cell death GO:0010623 138 0.015
protein catabolic process GO:0030163 101 0.015
organophosphate biosynthetic process GO:0090407 46 0.015
brain development GO:0007420 120 0.015
positive regulation of cell communication GO:0010647 250 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
determination of adult lifespan GO:0008340 137 0.015
establishment of vesicle localization GO:0051650 51 0.015
negative regulation of transcription dna templated GO:0045892 237 0.014
regulation of programmed cell death GO:0043067 152 0.014
aromatic compound catabolic process GO:0019439 166 0.014
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.014
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 4 0.014
positive regulation of cell proliferation GO:0008284 47 0.014
Human
meiotic nuclear division GO:0007126 151 0.014
ribonucleoprotein complex subunit organization GO:0071826 28 0.014
centriole replication GO:0007099 24 0.014
regulation of cell death GO:0010941 173 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
response to wounding GO:0009611 94 0.014
regulation of actin polymerization or depolymerization GO:0008064 27 0.014
positive regulation of neuron apoptotic process GO:0043525 1 0.014
cell cycle phase transition GO:0044770 140 0.014
Human
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
striated muscle myosin thick filament assembly GO:0071688 3 0.013
regulation of actin cytoskeleton organization GO:0032956 42 0.013
regulation of localization GO:0032879 275 0.013
response to external biotic stimulus GO:0043207 293 0.013
posttranscriptional gene silencing by rna GO:0035194 45 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
reproductive behavior GO:0019098 122 0.013
positive regulation of cell cycle GO:0045787 43 0.013
Human
salivary gland development GO:0007431 162 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
pupal development GO:0035209 11 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
sister chromatid segregation GO:0000819 92 0.013
digestive tract morphogenesis GO:0048546 127 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
heart process GO:0003015 37 0.012
positive regulation of proteolysis GO:0045862 52 0.012
regulation of chromosome segregation GO:0051983 32 0.012
negative regulation of erbb signaling pathway GO:1901185 29 0.012
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.012
aging GO:0007568 143 0.012
regulation of mitotic sister chromatid separation GO:0010965 28 0.012
muscle structure development GO:0061061 224 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
cellular homeostasis GO:0019725 80 0.012
phagocytosis GO:0006909 215 0.012
Fly
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.012
centriole assembly GO:0098534 24 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
positive regulation of catabolic process GO:0009896 105 0.012
regulation of protein modification process GO:0031399 112 0.012
imaginal disc fusion thorax closure GO:0046529 19 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
histolysis GO:0007559 102 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
atp dependent chromatin remodeling GO:0043044 22 0.012
ribonucleoside catabolic process GO:0042454 112 0.011
response to other organism GO:0051707 293 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
protein complex assembly GO:0006461 200 0.011
multicellular organismal aging GO:0010259 140 0.011
spermatogenesis GO:0007283 200 0.011
regulation of sister chromatid segregation GO:0033045 28 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
Human
maintenance of protein location in cell GO:0032507 26 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
oocyte dorsal ventral axis specification GO:0007310 34 0.011
regulation of cell proliferation GO:0042127 163 0.011
Human
negative regulation of cell death GO:0060548 81 0.011
response to oxygen containing compound GO:1901700 200 0.011
tissue morphogenesis GO:0048729 297 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
protein transport GO:0015031 155 0.011
camera type eye morphogenesis GO:0048593 2 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
single organism intracellular transport GO:1902582 207 0.011
regulation of mrna catabolic process GO:0061013 5 0.011
amine metabolic process GO:0009308 12 0.011
covalent chromatin modification GO:0016569 106 0.010
single organism catabolic process GO:0044712 228 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
regulation of molecular function GO:0065009 217 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
cellular response to oxygen levels GO:0071453 30 0.010
neuron fate commitment GO:0048663 50 0.010
regulation of cell cycle GO:0051726 291 0.010
Human

l(1)G0148 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.025
neurodegenerative disease DOID:1289 0 0.012
central nervous system disease DOID:331 0 0.012