Drosophila melanogaster

101 known processes

okr (Dmel_CG3736)

okra

(Aliases: rad54,CG3736,DmRAD54,RAD54L,Dmel\CG3736,Rad54,RAD54,Ras54,Dmrad54,DhR54,DmRad54)

okr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.998
double strand break repair GO:0006302 26 0.998
dna repair GO:0006281 54 0.996
recombinational repair GO:0000725 13 0.983
meiotic cell cycle GO:0051321 171 0.982
meiotic chromosome segregation GO:0045132 59 0.977
karyosome formation GO:0030717 22 0.971
dna metabolic process GO:0006259 227 0.961
nuclear division GO:0000280 332 0.939
cellular response to dna damage stimulus GO:0006974 223 0.939
non recombinational repair GO:0000726 7 0.937
meiotic nuclear division GO:0007126 151 0.935
reciprocal meiotic recombination GO:0007131 19 0.930
double strand break repair via nonhomologous end joining GO:0006303 5 0.920
dna recombination GO:0006310 32 0.894
chorion containing eggshell formation GO:0007304 105 0.891
meiotic cell cycle process GO:1903046 132 0.846
germarium derived oocyte fate determination GO:0007294 26 0.827
double strand break repair via homologous recombination GO:0000724 13 0.786
mitotic recombination GO:0006312 2 0.774
Yeast
dna synthesis involved in dna repair GO:0000731 5 0.740
organelle fission GO:0048285 340 0.721
meiosis i GO:0007127 59 0.716
dna conformation change GO:0071103 105 0.698
Yeast
eggshell chorion assembly GO:0007306 66 0.697
protein modification process GO:0036211 438 0.695
chromosome organization GO:0051276 360 0.695
telomere maintenance via recombination GO:0000722 1 0.667
Yeast
cellular component assembly involved in morphogenesis GO:0010927 151 0.647
germarium derived egg chamber formation GO:0007293 101 0.637
regulation of mitotic cell cycle GO:0007346 190 0.621
chromosome segregation GO:0007059 157 0.607
oocyte fate determination GO:0030716 27 0.570
dna double strand break processing GO:0000729 3 0.552
regulation of cell cycle phase transition GO:1901987 130 0.535
anterior posterior axis specification GO:0009948 109 0.505
mitotic dna damage checkpoint GO:0044773 74 0.494
polarity specification of dorsal ventral axis GO:0009951 6 0.493
regulation of cell cycle GO:0051726 291 0.413
telomere organization GO:0032200 21 0.371
Yeast
nucleotide excision repair GO:0006289 8 0.366
mitotic cell cycle checkpoint GO:0007093 88 0.351
dna geometric change GO:0032392 16 0.347
Yeast
regulation of mitotic cell cycle phase transition GO:1901990 130 0.316
meiotic chromosome separation GO:0051307 8 0.312
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.306
ovarian follicle cell development GO:0030707 248 0.304
mitotic nuclear division GO:0007067 213 0.300
cell cycle checkpoint GO:0000075 95 0.295
epithelial cell differentiation GO:0030855 322 0.277
anatomical structure homeostasis GO:0060249 97 0.274
Yeast
negative regulation of cellular metabolic process GO:0031324 382 0.273
dna biosynthetic process GO:0071897 24 0.271
negative regulation of cell cycle GO:0045786 116 0.270
cell cycle phase transition GO:0044770 140 0.266
regulation of cell cycle process GO:0010564 181 0.262
regionalization GO:0003002 416 0.239
homeostatic process GO:0042592 199 0.234
Yeast
negative regulation of cellular biosynthetic process GO:0031327 277 0.234
dna damage checkpoint GO:0000077 78 0.230
negative regulation of mitotic cell cycle GO:0045930 109 0.229
germarium derived oocyte differentiation GO:0030706 29 0.228
negative regulation of gene expression GO:0010629 387 0.222
dna packaging GO:0006323 91 0.211
endocytosis GO:0006897 310 0.203
cellular macromolecule localization GO:0070727 220 0.201
reciprocal dna recombination GO:0035825 19 0.198
intracellular mrna localization GO:0008298 66 0.195
cellular protein modification process GO:0006464 438 0.186
small molecule metabolic process GO:0044281 305 0.186
Yeast Zebrafish
cell division GO:0051301 248 0.179
rna localization GO:0006403 115 0.157
dna amplification GO:0006277 11 0.156
dorsal appendage formation GO:0046843 47 0.156
cellular homeostasis GO:0019725 80 0.153
protein phosphorylation GO:0006468 169 0.143
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.139
Yeast Zebrafish
negative regulation of cell cycle phase transition GO:1901988 103 0.130
macromolecular complex assembly GO:0065003 256 0.126
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.120
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.119
polarity specification of anterior posterior axis GO:0009949 5 0.119
gene silencing GO:0016458 138 0.113
programmed cell death GO:0012501 257 0.109
organic cyclic compound catabolic process GO:1901361 168 0.106
Yeast Zebrafish
ribose phosphate metabolic process GO:0019693 145 0.102
Yeast Zebrafish
response to radiation GO:0009314 155 0.101
female meiosis chromosome segregation GO:0016321 33 0.100
aromatic compound catabolic process GO:0019439 166 0.094
Yeast Zebrafish
oocyte dorsal ventral axis specification GO:0007310 34 0.094
regulation of protein metabolic process GO:0051246 256 0.094
female meiotic division GO:0007143 70 0.094
nucleus organization GO:0006997 45 0.091
postreplication repair GO:0006301 2 0.091
mitotic dna integrity checkpoint GO:0044774 75 0.090
cell death GO:0008219 279 0.090
chromosome condensation GO:0030261 41 0.088
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.088
Yeast
purine ribonucleoside catabolic process GO:0046130 112 0.088
Yeast Zebrafish
ribonucleoside metabolic process GO:0009119 127 0.087
Yeast Zebrafish
regulation of dna replication GO:0006275 13 0.087
regulation of cellular protein metabolic process GO:0032268 243 0.086
ncrna metabolic process GO:0034660 43 0.085
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.084
dna duplex unwinding GO:0032508 16 0.084
organic substance catabolic process GO:1901575 308 0.083
Yeast Zebrafish
regulation of dna recombination GO:0000018 4 0.080
negative regulation of biosynthetic process GO:0009890 277 0.079
negative regulation of cell cycle process GO:0010948 109 0.079
cellular nitrogen compound catabolic process GO:0044270 165 0.076
Yeast Zebrafish
regulation of meiosis GO:0040020 3 0.076
nucleobase containing compound catabolic process GO:0034655 165 0.076
Yeast Zebrafish
establishment or maintenance of cell polarity GO:0007163 167 0.072
phosphorylation GO:0016310 294 0.070
specification of axis polarity GO:0065001 6 0.069
response to organic substance GO:0010033 284 0.067
dna integrity checkpoint GO:0031570 81 0.067
positive regulation of cellular biosynthetic process GO:0031328 316 0.066
g2 dna damage checkpoint GO:0031572 69 0.062
cellular macromolecular complex assembly GO:0034622 153 0.061
single organism cellular localization GO:1902580 180 0.060
eggshell chorion gene amplification GO:0007307 9 0.058
nucleotide metabolic process GO:0009117 161 0.058
Yeast Zebrafish
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.057
columnar cuboidal epithelial cell development GO:0002066 249 0.057
chromosome separation GO:0051304 42 0.057
positive regulation of molecular function GO:0044093 136 0.056
Yeast
positive regulation of biosynthetic process GO:0009891 316 0.056
cellular macromolecule catabolic process GO:0044265 136 0.056
Yeast
response to oxygen containing compound GO:1901700 200 0.055
protein localization to organelle GO:0033365 82 0.054
vesicle mediated transport GO:0016192 381 0.054
positive regulation of nucleic acid templated transcription GO:1903508 266 0.054
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.053
Yeast Zebrafish
ribonucleoside catabolic process GO:0042454 112 0.052
Yeast Zebrafish
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.051
regulation of multicellular organismal development GO:2000026 414 0.051
regulation of cellular component biogenesis GO:0044087 201 0.051
death GO:0016265 284 0.050
mitotic g2 m transition checkpoint GO:0044818 70 0.050
cytoplasm organization GO:0007028 64 0.048
regulation of dna metabolic process GO:0051052 34 0.048
Yeast
regulation of molecular function GO:0065009 217 0.047
Yeast
mitotic cell cycle phase transition GO:0044772 138 0.047
oocyte differentiation GO:0009994 145 0.047
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.047
cellular response to radiation GO:0071478 52 0.045
ion transport GO:0006811 145 0.044
protein complex assembly GO:0006461 200 0.044
protein dna complex subunit organization GO:0071824 86 0.043
dorsal ventral axis specification GO:0009950 66 0.041
negative regulation of rna biosynthetic process GO:1902679 240 0.041
negative regulation of transcription dna templated GO:0045892 237 0.040
mitotic g2 dna damage checkpoint GO:0007095 69 0.039
organelle assembly GO:0070925 198 0.038
embryo development ending in birth or egg hatching GO:0009792 152 0.037
purine nucleotide metabolic process GO:0006163 146 0.037
Yeast Zebrafish
cell maturation GO:0048469 144 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.036
Yeast
cellular catabolic process GO:0044248 372 0.036
Yeast Zebrafish
nucleoside phosphate metabolic process GO:0006753 162 0.034
Yeast Zebrafish
negative regulation of dna recombination GO:0045910 2 0.034
catabolic process GO:0009056 409 0.034
Yeast Zebrafish
regulation of phosphorus metabolic process GO:0051174 210 0.033
macromolecule catabolic process GO:0009057 161 0.033
Yeast
response to organic cyclic compound GO:0014070 89 0.033
organelle localization GO:0051640 148 0.033
regulation of embryonic development GO:0045995 68 0.032
anterior posterior pattern specification GO:0009952 136 0.032
heterocycle catabolic process GO:0046700 166 0.032
Yeast Zebrafish
protein complex biogenesis GO:0070271 201 0.032
cellular response to abiotic stimulus GO:0071214 58 0.031
apoptotic process GO:0006915 159 0.031
intracellular signal transduction GO:0035556 300 0.031
cell motility GO:0048870 251 0.030
establishment of organelle localization GO:0051656 122 0.030
positive regulation of cellular catabolic process GO:0031331 95 0.029
Yeast
purine ribonucleoside metabolic process GO:0046128 127 0.029
Yeast Zebrafish
purine containing compound catabolic process GO:0072523 112 0.029
Yeast Zebrafish
ribonucleotide metabolic process GO:0009259 145 0.029
Yeast Zebrafish
epithelial cell development GO:0002064 274 0.028
response to ionizing radiation GO:0010212 32 0.028
protein localization GO:0008104 284 0.028
positive regulation of rna biosynthetic process GO:1902680 266 0.027
modification dependent protein catabolic process GO:0019941 78 0.027
regulation of cell division GO:0051302 72 0.027
chromatin organization GO:0006325 207 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
regulation of double strand break repair GO:2000779 3 0.026
regulation of cellular localization GO:0060341 136 0.026
cell fate determination GO:0001709 91 0.026
regulation of cell cycle g1 s phase transition GO:1902806 23 0.026
dorsal ventral pattern formation GO:0009953 133 0.026
response to abiotic stimulus GO:0009628 341 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.025
regulation of protein modification process GO:0031399 112 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
regulation of apoptotic process GO:0042981 130 0.025
single organism catabolic process GO:0044712 228 0.025
Yeast Zebrafish
response to bacterium GO:0009617 198 0.024
organonitrogen compound metabolic process GO:1901564 318 0.024
Yeast Zebrafish
immune system process GO:0002376 347 0.023
positive regulation of catalytic activity GO:0043085 118 0.023
Yeast
oocyte anterior posterior axis specification GO:0007314 72 0.022
organophosphate catabolic process GO:0046434 112 0.022
Yeast Zebrafish
protein localization to nucleus GO:0034504 55 0.022
negative regulation of nucleic acid templated transcription GO:1903507 240 0.022
proteolysis GO:0006508 192 0.021
cell cycle dna replication GO:0044786 23 0.021
nucleoside triphosphate metabolic process GO:0009141 120 0.021
Yeast Zebrafish
negative regulation of cell division GO:0051782 17 0.021
sister chromatid segregation GO:0000819 92 0.021
positive regulation of transcription dna templated GO:0045893 266 0.021
protein transport GO:0015031 155 0.020
single organism intracellular transport GO:1902582 207 0.020
oxoacid metabolic process GO:0043436 103 0.020
regulation of catalytic activity GO:0050790 185 0.020
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 108 0.020
Yeast Zebrafish
mitotic sister chromatid segregation GO:0000070 87 0.020
regulation of meiotic cell cycle GO:0051445 9 0.019
aging GO:0007568 143 0.019
response to nitrogen compound GO:1901698 90 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
Yeast Zebrafish
positive regulation of gene expression GO:0010628 290 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
sex differentiation GO:0007548 81 0.018
telomere maintenance GO:0000723 21 0.018
Yeast
protein catabolic process GO:0030163 101 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
Yeast Zebrafish
chromosome organization involved in meiosis GO:0070192 10 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
Yeast Zebrafish
negative regulation of response to stimulus GO:0048585 258 0.018
response to other organism GO:0051707 293 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
pirna metabolic process GO:0034587 10 0.017
nuclear dna replication GO:0033260 1 0.017
oocyte construction GO:0007308 112 0.017
purine nucleotide catabolic process GO:0006195 109 0.016
Yeast Zebrafish
cellular response to organic substance GO:0071310 132 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.016
Yeast Zebrafish
regulation of protein phosphorylation GO:0001932 64 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
regulation of response to stress GO:0080134 200 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
protein modification by small protein conjugation or removal GO:0070647 106 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
Yeast
negative regulation of cell differentiation GO:0045596 143 0.016
establishment of protein localization GO:0045184 163 0.016
segmentation GO:0035282 207 0.015
regulation of transferase activity GO:0051338 58 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
positive regulation of signaling GO:0023056 243 0.015
positive regulation of proteolysis GO:0045862 52 0.015
phagocytosis GO:0006909 215 0.015
axis specification GO:0009798 167 0.015
positive regulation of cell cycle process GO:0090068 28 0.014
regulation of cellular protein catabolic process GO:1903362 44 0.014
secretion GO:0046903 109 0.014
regulation of protein catabolic process GO:0042176 55 0.014
cellular protein localization GO:0034613 160 0.014
cellular amine metabolic process GO:0044106 12 0.014
dna replication GO:0006260 48 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
Yeast
regulation of proteolysis GO:0030162 87 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
negative regulation of transposition GO:0010529 12 0.014
blastoderm segmentation GO:0007350 159 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
Yeast Zebrafish
organonitrogen compound catabolic process GO:1901565 128 0.014
Yeast Zebrafish
positive regulation of developmental process GO:0051094 143 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.013
translesion synthesis GO:0019985 2 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
metal ion transport GO:0030001 74 0.013
response to light stimulus GO:0009416 124 0.013
regulation of hemocyte proliferation GO:0035206 37 0.013
rna processing GO:0006396 147 0.013
wing disc morphogenesis GO:0007472 344 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
Yeast Zebrafish
nucleoside phosphate catabolic process GO:1901292 110 0.013
Yeast Zebrafish
cellular response to ionizing radiation GO:0071479 15 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
cellular ketone metabolic process GO:0042180 24 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
cell migration GO:0016477 238 0.012
nucleoside metabolic process GO:0009116 127 0.012
Yeast Zebrafish
cellular response to organic cyclic compound GO:0071407 32 0.012
regulation of proteasomal protein catabolic process GO:0061136 39 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
pole plasm assembly GO:0007315 61 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
chromatin silencing GO:0006342 76 0.012
cell cycle arrest GO:0007050 4 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
cellular protein complex assembly GO:0043623 71 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
negative regulation of cell communication GO:0010648 223 0.011
organophosphate metabolic process GO:0019637 195 0.011
Yeast Zebrafish
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
nucleobase containing compound transport GO:0015931 56 0.011
secretion by cell GO:0032940 101 0.011
regulation of transposition rna mediated GO:0010525 3 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
Yeast Zebrafish
regulation of transposition GO:0010528 13 0.011
dna catabolic process GO:0006308 16 0.011
Yeast
transcription from rna polymerase ii promoter GO:0006366 368 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
single organism biosynthetic process GO:0044711 206 0.011
regulation of programmed cell death GO:0043067 152 0.011
regulation of protein kinase activity GO:0045859 51 0.011
cell proliferation GO:0008283 299 0.011
protein dna complex assembly GO:0065004 63 0.011
response to uv GO:0009411 24 0.011
response to external biotic stimulus GO:0043207 293 0.011
regulation of cell proliferation GO:0042127 163 0.010
multicellular organismal aging GO:0010259 140 0.010
embryonic pattern specification GO:0009880 174 0.010
regulation of phosphorylation GO:0042325 147 0.010
compound eye morphogenesis GO:0001745 249 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
Yeast Zebrafish
negative regulation of protein processing GO:0010955 31 0.010

okr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
disease of cellular proliferation DOID:14566 0 0.026
Human
thoracic cancer DOID:5093 0 0.012
Human
cancer DOID:162 0 0.012
Human
organ system cancer DOID:0050686 0 0.012
Human