Drosophila melanogaster

0 known processes

Paf-AHalpha (Dmel_CG8962)

Platelet-activating factor acetylhydrolase alpha

(Aliases: PAFAHalpha,Dmaalpha[[PAFAH]],Dmel\CG8962,AAC83820,CG8962)

Paf-AHalpha biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular biosynthetic process GO:0031327 277 0.316
establishment or maintenance of cell polarity GO:0007163 167 0.305
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.296
negative regulation of nucleic acid templated transcription GO:1903507 240 0.225
negative regulation of rna biosynthetic process GO:1902679 240 0.216
cellular protein modification process GO:0006464 438 0.195
negative regulation of biosynthetic process GO:0009890 277 0.171
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.164
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.147
regulation of phosphate metabolic process GO:0019220 210 0.142
negative regulation of rna metabolic process GO:0051253 251 0.132
chromosome organization GO:0051276 360 0.104
death GO:0016265 284 0.088
phosphorylation GO:0016310 294 0.081
negative regulation of cellular metabolic process GO:0031324 382 0.079
regulation of cellular component biogenesis GO:0044087 201 0.078
negative regulation of transcription dna templated GO:0045892 237 0.076
organelle assembly GO:0070925 198 0.071
regulation of phosphorus metabolic process GO:0051174 210 0.067
chromatin organization GO:0006325 207 0.064
actin filament based process GO:0030029 220 0.063
regulation of multicellular organismal development GO:2000026 414 0.063
transcription from rna polymerase ii promoter GO:0006366 368 0.063
protein modification process GO:0036211 438 0.061
intracellular signal transduction GO:0035556 300 0.057
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.054
regulation of intracellular signal transduction GO:1902531 236 0.051
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.050
regulation of molecular function GO:0065009 217 0.050
chromatin modification GO:0016568 147 0.048
ovulation cycle GO:0042698 1 0.045
cell death GO:0008219 279 0.043
negative regulation of gene expression GO:0010629 387 0.043
regulation of protein metabolic process GO:0051246 256 0.042
catabolic process GO:0009056 409 0.041
cellular response to dna damage stimulus GO:0006974 223 0.040
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.040
sensory organ morphogenesis GO:0090596 260 0.039
regulation of cell cycle GO:0051726 291 0.039
cell division GO:0051301 248 0.038
organic substance catabolic process GO:1901575 308 0.038
vesicle mediated transport GO:0016192 381 0.034
regionalization GO:0003002 416 0.034
regulation of ras protein signal transduction GO:0046578 93 0.033
mitotic cell cycle phase transition GO:0044772 138 0.032
cell motility GO:0048870 251 0.032
negative regulation of cell cycle phase transition GO:1901988 103 0.032
ras protein signal transduction GO:0007265 88 0.031
organonitrogen compound metabolic process GO:1901564 318 0.030
programmed cell death GO:0012501 257 0.030
actin cytoskeleton organization GO:0030036 206 0.028
oxoacid metabolic process GO:0043436 103 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.027
cellular catabolic process GO:0044248 372 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.026
covalent chromatin modification GO:0016569 106 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
aromatic compound catabolic process GO:0019439 166 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.023
positive regulation of cell communication GO:0010647 250 0.023
macromolecular complex assembly GO:0065003 256 0.023
small gtpase mediated signal transduction GO:0007264 88 0.023
histone modification GO:0016570 106 0.022
intracellular transport GO:0046907 228 0.022
cellular amino acid metabolic process GO:0006520 61 0.021
stem cell division GO:0017145 69 0.021
nitric oxide metabolic process GO:0046209 1 0.021
regulation of cell cycle phase transition GO:1901987 130 0.020
multi multicellular organism process GO:0044706 123 0.020
regulation of catalytic activity GO:0050790 185 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
protein phosphorylation GO:0006468 169 0.020
signal transduction by phosphorylation GO:0023014 107 0.019
oocyte axis specification GO:0007309 108 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
negative regulation of developmental process GO:0051093 201 0.019
muscle organ development GO:0007517 127 0.019
dephosphorylation GO:0016311 51 0.019
single organism cellular localization GO:1902580 180 0.019
regulation of organelle organization GO:0033043 196 0.019
embryonic pattern specification GO:0009880 174 0.019
protein complex biogenesis GO:0070271 201 0.018
protein localization GO:0008104 284 0.017
regulation of protein modification process GO:0031399 112 0.017
localization of cell GO:0051674 257 0.017
positive regulation of protein complex assembly GO:0031334 22 0.017
cell proliferation GO:0008283 299 0.016
regulation of cell cycle process GO:0010564 181 0.016
cell cycle checkpoint GO:0000075 95 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
positive regulation of cellular component organization GO:0051130 156 0.015
cellular component assembly involved in morphogenesis GO:0010927 151 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
regulation of cell differentiation GO:0045595 302 0.015
cellular macromolecule catabolic process GO:0044265 136 0.014
formation of a compartment boundary GO:0060288 4 0.014
regulation of nervous system development GO:0051960 248 0.014
heterocycle catabolic process GO:0046700 166 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
negative regulation of cell communication GO:0010648 223 0.014
apoptotic process GO:0006915 159 0.013
regulation of cell death GO:0010941 173 0.013
organelle inheritance GO:0048308 2 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
regulation of syncytial blastoderm mitotic cell cycle GO:0007348 4 0.013
axis specification GO:0009798 167 0.013
single organism biosynthetic process GO:0044711 206 0.013
response to biotic stimulus GO:0009607 294 0.013
mitotic g2 dna damage checkpoint GO:0007095 69 0.013
histone exchange GO:0043486 21 0.013
negative regulation of signal transduction GO:0009968 206 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
mapk cascade GO:0000165 107 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
nucleosome organization GO:0034728 59 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
wing disc morphogenesis GO:0007472 344 0.012
nuclear division GO:0000280 332 0.012
developmental maturation GO:0021700 172 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
organic acid metabolic process GO:0006082 103 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
photoreceptor cell differentiation GO:0046530 170 0.011
regulation of mapk cascade GO:0043408 92 0.011
small molecule metabolic process GO:0044281 305 0.011
nucleotide metabolic process GO:0009117 161 0.011
cell cycle phase transition GO:0044770 140 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
dendrite development GO:0016358 204 0.011
negative regulation of signaling GO:0023057 219 0.011
progression of morphogenetic furrow involved in compound eye morphogenesis GO:0007458 8 0.011
cytoplasmic transport GO:0016482 130 0.010
positive regulation of cellular biosynthetic process GO:0031328 316 0.010
appendage morphogenesis GO:0035107 397 0.010
oocyte development GO:0048599 124 0.010
chromosome segregation GO:0007059 157 0.010
establishment of cell polarity GO:0030010 40 0.010

Paf-AHalpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 0 0.014
osteogenesis imperfecta DOID:12347 0 0.014
bone development disease DOID:0080006 0 0.014
bone disease DOID:0080001 0 0.014
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014