Drosophila melanogaster

72 known processes

Pur-alpha (Dmel_CG1507)

Purine-rich binding protein-alpha

(Aliases: pur-alpha,Pur-a,PURalpha,CG1507,Dmel\CG1507)

Pur-alpha biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna damage checkpoint GO:0000077 78 0.322
cell division GO:0051301 248 0.172
dna metabolic process GO:0006259 227 0.157
imaginal disc derived appendage development GO:0048737 399 0.140
immune system process GO:0002376 347 0.136
organelle assembly GO:0070925 198 0.129
negative regulation of cellular metabolic process GO:0031324 382 0.111
imaginal disc derived appendage morphogenesis GO:0035114 395 0.106
regulation of gene expression epigenetic GO:0040029 128 0.106
response to light stimulus GO:0009416 124 0.104
post embryonic appendage morphogenesis GO:0035120 385 0.098
cellular response to dna damage stimulus GO:0006974 223 0.096
endocytosis GO:0006897 310 0.091
gene silencing GO:0016458 138 0.090
response to radiation GO:0009314 155 0.087
vesicle mediated transport GO:0016192 381 0.082
single organism behavior GO:0044708 391 0.080
proteolysis GO:0006508 192 0.080
appendage development GO:0048736 401 0.078
imaginal disc derived wing morphogenesis GO:0007476 337 0.077
regulation of molecular function GO:0065009 217 0.071
learning or memory GO:0007611 141 0.069
taxis GO:0042330 304 0.065
regulation of neurogenesis GO:0050767 158 0.064
response to abiotic stimulus GO:0009628 341 0.064
regulation of cell division GO:0051302 72 0.063
regulation of organelle organization GO:0033043 196 0.063
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.059
regulation of cell cycle process GO:0010564 181 0.058
establishment of localization in cell GO:0051649 402 0.057
protein transport GO:0015031 155 0.056
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.056
regulation of phosphorus metabolic process GO:0051174 210 0.055
wing disc morphogenesis GO:0007472 344 0.054
organelle fission GO:0048285 340 0.054
dna integrity checkpoint GO:0031570 81 0.053
neurological system process GO:0050877 358 0.052
protein modification process GO:0036211 438 0.051
regulation of multicellular organismal development GO:2000026 414 0.051
regulation of nervous system development GO:0051960 248 0.051
cell cycle checkpoint GO:0000075 95 0.051
regulation of cell cycle GO:0051726 291 0.051
regulation of meiosis GO:0040020 3 0.049
regulation of proteolysis GO:0030162 87 0.048
cognition GO:0050890 141 0.048
regulation of response to external stimulus GO:0032101 115 0.045
peptidyl threonine phosphorylation GO:0018107 2 0.045
regulation of protein metabolic process GO:0051246 256 0.045
positive regulation of response to stimulus GO:0048584 323 0.044
regulation of synapse structure and activity GO:0050803 128 0.043
appendage morphogenesis GO:0035107 397 0.042
response to organic substance GO:0010033 284 0.041
regulation of multi organism process GO:0043900 131 0.041
regulation of response to stress GO:0080134 200 0.041
cellular response to abiotic stimulus GO:0071214 58 0.041
synapse organization GO:0050808 196 0.040
organelle localization GO:0051640 148 0.040
meiotic nuclear division GO:0007126 151 0.039
negative regulation of gene expression epigenetic GO:0045814 77 0.038
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.038
programmed cell death GO:0012501 257 0.038
regulation of programmed cell death GO:0043067 152 0.036
regulation of cellular ketone metabolic process GO:0010565 3 0.036
negative regulation of cell cycle GO:0045786 116 0.036
cellular protein modification process GO:0006464 438 0.035
chemotaxis GO:0006935 249 0.035
phagocytosis GO:0006909 215 0.035
regulation of localization GO:0032879 275 0.034
negative regulation of biosynthetic process GO:0009890 277 0.034
regulation of cell development GO:0060284 215 0.033
embryonic morphogenesis GO:0048598 206 0.033
positive regulation of macromolecule metabolic process GO:0010604 405 0.033
negative regulation of cellular biosynthetic process GO:0031327 277 0.033
sensory perception of chemical stimulus GO:0007606 116 0.033
organonitrogen compound metabolic process GO:1901564 318 0.032
synaptic transmission GO:0007268 288 0.032
chromatin modification GO:0016568 147 0.032
intracellular transport GO:0046907 228 0.031
regulation of cellular component biogenesis GO:0044087 201 0.031
chromosome organization GO:0051276 360 0.031
memory GO:0007613 94 0.031
negative regulation of developmental process GO:0051093 201 0.030
negative regulation of rna biosynthetic process GO:1902679 240 0.030
spindle organization GO:0007051 253 0.030
cell migration GO:0016477 238 0.029
telencephalon development GO:0021537 2 0.029
regulation of cell differentiation GO:0045595 302 0.029
cellular response to chemical stimulus GO:0070887 199 0.029
cellular ketone metabolic process GO:0042180 24 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
response to carbon dioxide GO:0010037 4 0.028
regulation of phosphorylation GO:0042325 147 0.028
regulation of catalytic activity GO:0050790 185 0.028
regulation of cell death GO:0010941 173 0.028
cell death GO:0008219 279 0.028
protein phosphorylation GO:0006468 169 0.027
regulation of protein localization GO:0032880 76 0.027
cilium assembly GO:0042384 38 0.027
positive regulation of cellular component organization GO:0051130 156 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
long term memory GO:0007616 62 0.027
positive regulation of response to external stimulus GO:0032103 44 0.026
mitotic cell cycle checkpoint GO:0007093 88 0.026
positive regulation of behavior GO:0048520 19 0.026
negative regulation of response to stimulus GO:0048585 258 0.026
cell cycle phase transition GO:0044770 140 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.026
meiotic cell cycle GO:0051321 171 0.026
morphogenesis of an epithelium GO:0002009 276 0.025
macromolecular complex assembly GO:0065003 256 0.025
death GO:0016265 284 0.025
body morphogenesis GO:0010171 2 0.024
asymmetric stem cell division GO:0098722 49 0.024
negative regulation of cellular component organization GO:0051129 108 0.024
regulation of catabolic process GO:0009894 170 0.023
spinal cord development GO:0021510 1 0.023
cell adhesion GO:0007155 136 0.023
homeostatic process GO:0042592 199 0.023
axon development GO:0061564 297 0.023
g1 s transition of mitotic cell cycle GO:0000082 31 0.023
cilium organization GO:0044782 41 0.023
tube morphogenesis GO:0035239 191 0.022
meiotic cell cycle process GO:1903046 132 0.022
leg disc development GO:0035218 92 0.022
single organism membrane fusion GO:0044801 42 0.022
intracellular signal transduction GO:0035556 300 0.022
positive regulation of catalytic activity GO:0043085 118 0.022
lateral inhibition GO:0046331 206 0.022
amine metabolic process GO:0009308 12 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
organic substance transport GO:0071702 257 0.021
positive regulation of cell differentiation GO:0045597 64 0.021
positive regulation of protein metabolic process GO:0051247 128 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
tissue morphogenesis GO:0048729 297 0.021
regulation of nuclear division GO:0051783 58 0.021
negative regulation of cell communication GO:0010648 223 0.021
single organism intracellular transport GO:1902582 207 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
stem cell division GO:0017145 69 0.021
cellular catabolic process GO:0044248 372 0.021
camera type eye morphogenesis GO:0048593 2 0.021
regulation of microtubule based process GO:0032886 49 0.020
cytokinesis GO:0000910 90 0.020
ion transport GO:0006811 145 0.020
apoptotic process GO:0006915 159 0.020
posttranscriptional gene silencing by rna GO:0035194 45 0.020
cell chemotaxis GO:0060326 6 0.020
neuroblast proliferation GO:0007405 74 0.020
cell cell signaling involved in cell fate commitment GO:0045168 210 0.020
establishment of protein localization GO:0045184 163 0.020
positive regulation of cell death GO:0010942 69 0.020
response to oxygen containing compound GO:1901700 200 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
posttranscriptional regulation of gene expression GO:0010608 145 0.020
cell cell junction assembly GO:0007043 38 0.020
regulation of protein phosphorylation GO:0001932 64 0.019
protein modification by small protein conjugation or removal GO:0070647 106 0.019
neuronal stem cell division GO:0036445 35 0.019
monocarboxylic acid transport GO:0015718 3 0.019
embryonic development via the syncytial blastoderm GO:0001700 148 0.019
response to protozoan GO:0001562 3 0.019
negative regulation of catalytic activity GO:0043086 42 0.019
single organism biosynthetic process GO:0044711 206 0.019
defense response GO:0006952 300 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
regulation of synapse organization GO:0050807 110 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
mitotic nuclear division GO:0007067 213 0.018
regulation of cell cycle phase transition GO:1901987 130 0.018
chromatin organization GO:0006325 207 0.018
neuroblast division GO:0055057 35 0.018
dendrite development GO:0016358 204 0.018
positive regulation of developmental process GO:0051094 143 0.018
detection of abiotic stimulus GO:0009582 66 0.018
protein localization GO:0008104 284 0.018
positive regulation of molecular function GO:0044093 136 0.018
regulation of protein modification process GO:0031399 112 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.018
peptidyl threonine modification GO:0018210 3 0.018
regulation of behavior GO:0050795 75 0.018
phosphorylation GO:0016310 294 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.017
negative regulation of signaling GO:0023057 219 0.017
positive regulation of dendrite development GO:1900006 9 0.017
regulation of immune system process GO:0002682 176 0.017
positive regulation of cell migration GO:0030335 2 0.017
cellular response to radiation GO:0071478 52 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
negative regulation of protein metabolic process GO:0051248 85 0.017
regulation of dna metabolic process GO:0051052 34 0.017
cell recognition GO:0008037 102 0.017
positive regulation of cell communication GO:0010647 250 0.017
negative regulation of programmed cell death GO:0043069 72 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
protein complex biogenesis GO:0070271 201 0.017
regulation of immune effector process GO:0002697 52 0.017
small molecule metabolic process GO:0044281 305 0.017
cytoskeleton dependent cytokinesis GO:0061640 81 0.017
cellular component assembly involved in morphogenesis GO:0010927 151 0.017
neurotransmitter transport GO:0006836 37 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
microtubule bundle formation GO:0001578 27 0.017
regulation of transport GO:0051049 181 0.016
cellular response to starvation GO:0009267 61 0.016
single organism catabolic process GO:0044712 228 0.016
ras protein signal transduction GO:0007265 88 0.016
organic substance catabolic process GO:1901575 308 0.016
protein complex assembly GO:0006461 200 0.016
anatomical structure homeostasis GO:0060249 97 0.016
chromosome segregation GO:0007059 157 0.016
stem cell proliferation GO:0072089 88 0.016
catabolic process GO:0009056 409 0.016
imaginal disc derived leg morphogenesis GO:0007480 80 0.016
negative regulation of mitotic cell cycle GO:0045930 109 0.016
connective tissue development GO:0061448 3 0.016
vesicle localization GO:0051648 55 0.016
localization of cell GO:0051674 257 0.015
negative regulation of molecular function GO:0044092 51 0.015
histone modification GO:0016570 106 0.015
regulation of establishment of protein localization GO:0070201 61 0.015
response to glucose GO:0009749 2 0.015
response to oxygen levels GO:0070482 59 0.015
dna replication GO:0006260 48 0.015
positive regulation of signaling GO:0023056 243 0.015
regulation of vesicle mediated transport GO:0060627 59 0.015
cellular response to light stimulus GO:0071482 37 0.015
response to lipopolysaccharide GO:0032496 4 0.015
axon guidance GO:0007411 233 0.015
neuron recognition GO:0008038 101 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
cellular protein localization GO:0034613 160 0.015
eye development GO:0001654 323 0.015
regulation of cellular response to stress GO:0080135 89 0.015
detection of external stimulus GO:0009581 66 0.015
cellular response to nutrient levels GO:0031669 62 0.015
regulation of hydrolase activity GO:0051336 97 0.015
negative regulation of organelle organization GO:0010639 56 0.015
peptidyl amino acid modification GO:0018193 105 0.015
positive regulation of organelle organization GO:0010638 65 0.015
nuclear division GO:0000280 332 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
secretion GO:0046903 109 0.015
forebrain development GO:0030900 2 0.014
regulation of apoptotic process GO:0042981 130 0.014
epithelial tube morphogenesis GO:0060562 88 0.014
mitotic dna integrity checkpoint GO:0044774 75 0.014
regulation of cell shape GO:0008360 113 0.014
regulation of cell projection organization GO:0031344 92 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
biological adhesion GO:0022610 138 0.014
oxidation reduction process GO:0055114 123 0.014
multicellular organismal aging GO:0010259 140 0.014
response to biotic stimulus GO:0009607 294 0.014
microtubule organizing center organization GO:0031023 168 0.014
circadian behavior GO:0048512 76 0.014
camera type eye development GO:0043010 4 0.014
regulation of synaptic transmission GO:0050804 69 0.014
neural precursor cell proliferation GO:0061351 75 0.014
positive regulation of nervous system development GO:0051962 69 0.014
protein catabolic process GO:0030163 101 0.014
detection of stimulus GO:0051606 156 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
response to nitrogen compound GO:1901698 90 0.014
deactivation of rhodopsin mediated signaling GO:0016059 17 0.014
centrosome organization GO:0051297 163 0.014
neuron projection guidance GO:0097485 241 0.014
regulation of neuron differentiation GO:0045664 103 0.014
regulation of neuron projection development GO:0010975 69 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
negative regulation of cell death GO:0060548 81 0.013
negative regulation of cell cycle process GO:0010948 109 0.013
mitotic cytokinesis GO:0000281 50 0.013
smoothened signaling pathway GO:0007224 49 0.013
response to hexose GO:0009746 3 0.013
morphogenesis of embryonic epithelium GO:0016331 94 0.013
response to insulin GO:0032868 29 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
neurotransmitter secretion GO:0007269 35 0.013
protein k48 linked ubiquitination GO:0070936 3 0.013
regulation of cytoplasmic transport GO:1903649 47 0.013
regulation of rna splicing GO:0043484 69 0.013
gene silencing by rna GO:0031047 57 0.013
response to decreased oxygen levels GO:0036293 58 0.013
compound eye retinal cell programmed cell death GO:0046667 23 0.013
tube development GO:0035295 244 0.013
cellular response to carbohydrate stimulus GO:0071322 4 0.013
posttranscriptional gene silencing GO:0016441 46 0.013
negative regulation of gene expression GO:0010629 387 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
response to bacterium GO:0009617 198 0.013
mitotic spindle organization GO:0007052 220 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
mapk cascade GO:0000165 107 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
regulation of protein kinase activity GO:0045859 51 0.013
nuclear transport GO:0051169 72 0.013
very long chain fatty acid metabolic process GO:0000038 4 0.013
regulation of response to biotic stimulus GO:0002831 63 0.012
cellular macromolecule localization GO:0070727 220 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
cellular protein catabolic process GO:0044257 83 0.012
regulation of gene silencing GO:0060968 63 0.012
positive regulation of cell motility GO:2000147 3 0.012
regulation of chromosome organization GO:0033044 64 0.012
cell proliferation GO:0008283 299 0.012
long chain fatty acid metabolic process GO:0001676 3 0.012
intracellular protein transport GO:0006886 104 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
locomotory behavior GO:0007626 176 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
rhythmic process GO:0048511 106 0.012
positive regulation of transport GO:0051050 92 0.012
regulation of intracellular protein transport GO:0033157 46 0.012
defense response to bacterium GO:0042742 178 0.012
cell motility GO:0048870 251 0.012
macromolecule catabolic process GO:0009057 161 0.012
positive regulation of cell development GO:0010720 61 0.012
positive regulation of signal transduction GO:0009967 223 0.012
dendrite morphogenesis GO:0048813 199 0.012
sensory perception of smell GO:0007608 80 0.012
cellular response to extracellular stimulus GO:0031668 64 0.012
cellular response to organic substance GO:0071310 132 0.012
regulation of dendrite development GO:0050773 37 0.012
gland development GO:0048732 191 0.012
mesoderm development GO:0007498 78 0.012
muscle structure development GO:0061061 224 0.011
store operated calcium entry GO:0002115 3 0.011
positive regulation of cell projection organization GO:0031346 29 0.011
sister chromatid segregation GO:0000819 92 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
limb development GO:0060173 1 0.011
nucleotide metabolic process GO:0009117 161 0.011
response to extracellular stimulus GO:0009991 116 0.011
regulation of lipid transport GO:0032368 3 0.011
regulation of protein serine threonine kinase activity GO:0071900 25 0.011
regulation of meiotic cell cycle GO:0051445 9 0.011
negative regulation of nervous system development GO:0051961 92 0.011
fertilization GO:0009566 26 0.011
gastrulation with mouth forming first GO:0001703 36 0.011
response to monosaccharide GO:0034284 4 0.011
positive regulation of catabolic process GO:0009896 105 0.011
positive regulation of protein kinase activity GO:0045860 25 0.011
response to nutrient levels GO:0031667 114 0.011
response to uv GO:0009411 24 0.011
regulation of protein catabolic process GO:0042176 55 0.011
regulation of kinase activity GO:0043549 53 0.011
secretion by cell GO:0032940 101 0.011
covalent chromatin modification GO:0016569 106 0.011
oxoacid metabolic process GO:0043436 103 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
positive regulation of neurogenesis GO:0050769 41 0.011
kidney development GO:0001822 3 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
negative regulation of cellular catabolic process GO:0031330 34 0.011
branching involved in open tracheal system development GO:0060446 45 0.011
protein dna complex subunit organization GO:0071824 86 0.011
regulation of chemotaxis GO:0050920 12 0.011
cellular response to carbon dioxide GO:0071244 2 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
response to inorganic substance GO:0010035 44 0.011
response to external biotic stimulus GO:0043207 293 0.010
salivary gland morphogenesis GO:0007435 145 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
response to endogenous stimulus GO:0009719 119 0.010
regulation of cellular localization GO:0060341 136 0.010
regulation of lyase activity GO:0051339 14 0.010
regionalization GO:0003002 416 0.010
detection of visible light GO:0009584 38 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
negative regulation of cell cycle phase transition GO:1901988 103 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
immune system development GO:0002520 57 0.010
regulation of chromatin organization GO:1902275 32 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.010
chemical homeostasis GO:0048878 92 0.010
modification dependent protein catabolic process GO:0019941 78 0.010

Pur-alpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.010