|
|
negative regulation of signal transduction
|
GO:0009968 |
206 |
0.972
|
|
|
|
immune system process
|
GO:0002376 |
347 |
0.964
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
258 |
0.923
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
219 |
0.907
|
|
|
|
regulation of immune response
|
GO:0050776 |
118 |
0.816
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
24 |
0.770
|
|
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.730
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.698
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
57 |
0.696
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
223 |
0.685
|
|
|
|
regulation of growth
|
GO:0040008 |
233 |
0.662
|
Worm |
|
|
carboxylic acid metabolic process
|
GO:0019752 |
92 |
0.621
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
105 |
0.578
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
2 |
0.549
|
Mouse |
|
|
epithelial cell differentiation
|
GO:0030855 |
322 |
0.510
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.509
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.507
|
|
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.497
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.485
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
103 |
0.481
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.471
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
199 |
0.471
|
Zebrafish Mouse |
|
|
protein modification process
|
GO:0036211 |
438 |
0.464
|
|
|
|
regulation of immune system process
|
GO:0002682 |
176 |
0.463
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
302 |
0.460
|
|
|
|
innate immune response
|
GO:0045087 |
144 |
0.443
|
|
|
|
neuron projection guidance
|
GO:0097485 |
241 |
0.441
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
78 |
0.422
|
|
|
|
instar larval development
|
GO:0002168 |
55 |
0.415
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
305 |
0.402
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
256 |
0.396
|
|
|
|
growth
|
GO:0040007 |
359 |
0.372
|
Worm |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
2 |
0.368
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
35 |
0.365
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
103 |
0.364
|
|
|
|
immune response
|
GO:0006955 |
246 |
0.362
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
61 |
0.358
|
|
|
|
regionalization
|
GO:0003002 |
416 |
0.358
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
78 |
0.349
|
|
|
|
protein phosphorylation
|
GO:0006468 |
169 |
0.338
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
223 |
0.337
|
Mouse |
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.334
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
25 |
0.333
|
|
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
69 |
0.333
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
267 |
0.332
|
|
|
|
axonogenesis
|
GO:0007409 |
290 |
0.328
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
6 |
0.321
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
69 |
0.314
|
|
|
|
dorsal closure
|
GO:0007391 |
79 |
0.313
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
14 |
0.313
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
12 |
0.305
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
206 |
0.302
|
|
|
|
cell division
|
GO:0051301 |
248 |
0.300
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
179 |
0.295
|
|
|
|
negative regulation of synaptic growth at neuromuscular junction
|
GO:0045886 |
39 |
0.294
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
64 |
0.292
|
|
|
|
wing disc morphogenesis
|
GO:0007472 |
344 |
0.290
|
|
|
|
hemopoiesis
|
GO:0030097 |
46 |
0.286
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
152 |
0.286
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.284
|
|
|
|
defense response to bacterium
|
GO:0042742 |
178 |
0.282
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.264
|
|
|
|
taxis
|
GO:0042330 |
304 |
0.261
|
Zebrafish |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
16 |
0.257
|
|
|
|
catabolic process
|
GO:0009056 |
409 |
0.257
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
50 |
0.254
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
277 |
0.253
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
79 |
0.249
|
|
|
|
homeostatic process
|
GO:0042592 |
199 |
0.249
|
Mouse Fly |
|
|
defense response to other organism
|
GO:0098542 |
225 |
0.248
|
|
|
|
post embryonic appendage morphogenesis
|
GO:0035120 |
385 |
0.247
|
|
|
|
cell proliferation
|
GO:0008283 |
299 |
0.243
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
243 |
0.232
|
Mouse |
|
|
defense response
|
GO:0006952 |
300 |
0.227
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
57 |
0.225
|
|
|
|
response to virus
|
GO:0009615 |
28 |
0.222
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
51 |
0.218
|
|
|
|
embryonic development via the syncytial blastoderm
|
GO:0001700 |
148 |
0.212
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
53 |
0.210
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
397 |
0.210
|
|
|
|
appendage development
|
GO:0048736 |
401 |
0.209
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
72 |
0.209
|
Mouse |
|
|
developmental growth
|
GO:0048589 |
280 |
0.206
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
143 |
0.204
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
83 |
0.204
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
151 |
0.203
|
|
|
|
epithelial cell development
|
GO:0002064 |
274 |
0.195
|
|
|
|
chemotaxis
|
GO:0006935 |
249 |
0.194
|
Zebrafish |
|
|
response to temperature stimulus
|
GO:0009266 |
106 |
0.187
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
63 |
0.186
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
12 |
0.185
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
83 |
0.180
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
163 |
0.179
|
|
|
|
axon guidance
|
GO:0007411 |
233 |
0.179
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
271 |
0.177
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
143 |
0.175
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
17 |
0.174
|
|
|
|
response to oxidative stress
|
GO:0006979 |
86 |
0.173
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
36 |
0.173
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
116 |
0.165
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
46 |
0.164
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.164
|
Mouse |
|
|
axis specification
|
GO:0009798 |
167 |
0.162
|
|
|
|
developmental maturation
|
GO:0021700 |
172 |
0.162
|
|
|
|
response to other organism
|
GO:0051707 |
293 |
0.161
|
|
|
|
proteolysis
|
GO:0006508 |
192 |
0.161
|
Mouse |
|
|
tube development
|
GO:0035295 |
244 |
0.160
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
174 |
0.159
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.158
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
68 |
0.156
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.154
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
98 |
0.154
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
85 |
0.151
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
159 |
0.151
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
136 |
0.151
|
|
|
|
eye development
|
GO:0001654 |
323 |
0.148
|
|
|
|
spindle organization
|
GO:0007051 |
253 |
0.147
|
|
|
|
imaginal disc growth
|
GO:0007446 |
37 |
0.145
|
|
|
|
regulation of imaginal disc growth
|
GO:0045570 |
26 |
0.145
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
130 |
0.145
|
Mouse |
|
|
imaginal disc derived appendage development
|
GO:0048737 |
399 |
0.144
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
256 |
0.144
|
|
|
|
imaginal disc derived appendage morphogenesis
|
GO:0035114 |
395 |
0.141
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
52 |
0.140
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
59 |
0.140
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
2 |
0.140
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
92 |
0.139
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
291 |
0.138
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
174 |
0.137
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
3 |
0.136
|
|
|
|
positive regulation of antifungal peptide biosynthetic process
|
GO:0006967 |
5 |
0.135
|
|
|
|
oocyte development
|
GO:0048599 |
124 |
0.135
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
387 |
0.134
|
Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
83 |
0.133
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
341 |
0.133
|
Mouse Fly |
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
63 |
0.128
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
381 |
0.128
|
Mouse Fly |
|
|
response to external biotic stimulus
|
GO:0043207 |
293 |
0.127
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
206 |
0.126
|
|
|
|
digestive system development
|
GO:0055123 |
149 |
0.125
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
75 |
0.123
|
|
|
|
phosphorylation
|
GO:0016310 |
294 |
0.122
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
94 |
0.122
|
|
|
|
protein catabolic process
|
GO:0030163 |
101 |
0.121
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
39 |
0.121
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
17 |
0.121
|
|
|
|
molting cycle chitin based cuticle
|
GO:0007591 |
56 |
0.121
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
137 |
0.120
|
|
|
|
eye morphogenesis
|
GO:0048592 |
260 |
0.118
|
|
|
|
cell maturation
|
GO:0048469 |
144 |
0.117
|
|
|
|
regulation of localization
|
GO:0032879 |
275 |
0.116
|
Zebrafish Mouse |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
323 |
0.115
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
80 |
0.114
|
|
|
|
regulation of defense response
|
GO:0031347 |
102 |
0.113
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
277 |
0.113
|
|
|
|
secretion by cell
|
GO:0032940 |
101 |
0.110
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
149 |
0.109
|
|
|
|
synaptic transmission
|
GO:0007268 |
288 |
0.109
|
Mouse |
|
|
protein acetylation
|
GO:0006473 |
39 |
0.108
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
157 |
0.107
|
|
|
|
mapk cascade
|
GO:0000165 |
107 |
0.107
|
Mouse |
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
116 |
0.106
|
Mouse |
|
|
regulation of protein modification process
|
GO:0031399 |
112 |
0.105
|
|
|
|
imaginal disc derived wing vein specification
|
GO:0007474 |
48 |
0.105
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
45 |
0.102
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
85 |
0.100
|
|
|
|
response to organic substance
|
GO:0010033 |
284 |
0.099
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
87 |
0.098
|
Mouse |
|
|
regulation of synaptic transmission
|
GO:0050804 |
69 |
0.097
|
Mouse |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
44 |
0.097
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
240 |
0.097
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
308 |
0.096
|
|
|
|
notch signaling pathway
|
GO:0007219 |
120 |
0.095
|
|
|
|
oocyte construction
|
GO:0007308 |
112 |
0.095
|
|
|
|
negative regulation of fibroblast growth factor receptor signaling pathway
|
GO:0040037 |
2 |
0.095
|
|
|
|
regulation of response to stress
|
GO:0080134 |
200 |
0.094
|
|
|
|
phagocytosis
|
GO:0006909 |
215 |
0.094
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
131 |
0.093
|
|
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
249 |
0.092
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
74 |
0.092
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
167 |
0.092
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
294 |
0.090
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
28 |
0.090
|
|
|
|
regulation of organ growth
|
GO:0046620 |
42 |
0.089
|
|
|
|
synapse organization
|
GO:0050808 |
196 |
0.088
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
59 |
0.088
|
Mouse |
|
|
cell motility
|
GO:0048870 |
251 |
0.087
|
Zebrafish |
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
210 |
0.087
|
|
|
|
oocyte axis specification
|
GO:0007309 |
108 |
0.086
|
|
|
|
organ growth
|
GO:0035265 |
56 |
0.086
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
15 |
0.085
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
149 |
0.085
|
|
|
|
activation of mapk activity
|
GO:0000187 |
9 |
0.085
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
94 |
0.084
|
|
|
|
negative regulation of growth
|
GO:0045926 |
84 |
0.084
|
|
|
|
organic substance transport
|
GO:0071702 |
257 |
0.082
|
Mouse |
|
|
larval development
|
GO:0002164 |
104 |
0.081
|
|
|
|
ovarian follicle cell development
|
GO:0030707 |
248 |
0.081
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
152 |
0.080
|
Mouse |
|
|
positive regulation of immune system process
|
GO:0002684 |
68 |
0.080
|
Mouse |
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
6 |
0.079
|
|
|
|
connective tissue development
|
GO:0061448 |
3 |
0.079
|
|
|
|
dorsal ventral axis specification
|
GO:0009950 |
66 |
0.078
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
13 |
0.076
|
|
|
|
metal ion transport
|
GO:0030001 |
74 |
0.076
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
8 |
0.075
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
19 |
0.074
|
|
|
|
epithelial cell migration
|
GO:0010631 |
148 |
0.074
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
107 |
0.073
|
Mouse |
|
|
cuticle development
|
GO:0042335 |
86 |
0.073
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
24 |
0.072
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
100 |
0.072
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
200 |
0.072
|
Mouse |
|
|
positive regulation of developmental growth
|
GO:0048639 |
62 |
0.070
|
|
|
|
positive regulation of multicellular organism growth
|
GO:0040018 |
21 |
0.070
|
|
|
|
synapse assembly
|
GO:0007416 |
143 |
0.069
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
115 |
0.068
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
142 |
0.068
|
|
|
|
extracellular structure organization
|
GO:0043062 |
46 |
0.067
|
|
|
|
chorion containing eggshell formation
|
GO:0007304 |
105 |
0.067
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.067
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
181 |
0.067
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
147 |
0.066
|
|
|
|
immune system development
|
GO:0002520 |
57 |
0.066
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
132 |
0.066
|
Mouse |
|
|
response to heat
|
GO:0009408 |
63 |
0.065
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
52 |
0.065
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
4 |
0.065
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
128 |
0.065
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
4 |
0.065
|
|
|
|
molting cycle
|
GO:0042303 |
56 |
0.064
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
39 |
0.064
|
|
|
|
head involution
|
GO:0008258 |
35 |
0.063
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.063
|
|
|
|
positive regulation of growth
|
GO:0045927 |
75 |
0.063
|
Worm |
|
|
regulation of nervous system development
|
GO:0051960 |
248 |
0.062
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
41 |
0.062
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
28 |
0.062
|
|
|
|
toll signaling pathway
|
GO:0008063 |
25 |
0.062
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
3 |
0.061
|
|
|
|
histone h4 k16 acetylation
|
GO:0043984 |
4 |
0.061
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
44 |
0.061
|
|
|
|
memory
|
GO:0007613 |
94 |
0.060
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
276 |
0.059
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
140 |
0.058
|
|
|
|
urogenital system development
|
GO:0001655 |
72 |
0.058
|
|
|
|
nuclear division
|
GO:0000280 |
332 |
0.057
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
136 |
0.057
|
|
|
|
stem cell development
|
GO:0048864 |
79 |
0.056
|
|
|
|
axon development
|
GO:0061564 |
297 |
0.056
|
|
|
|
cell death
|
GO:0008219 |
279 |
0.056
|
Mouse |
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
20 |
0.056
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
25 |
0.056
|
Mouse |
|
|
regulation of cell division
|
GO:0051302 |
72 |
0.056
|
|
|
|
cytokinesis
|
GO:0000910 |
90 |
0.055
|
|
|
|
response to bacterium
|
GO:0009617 |
198 |
0.055
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
151 |
0.055
|
|
|
|
reproductive structure development
|
GO:0048608 |
74 |
0.055
|
|
|
|
developmental pigmentation
|
GO:0048066 |
68 |
0.055
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
140 |
0.054
|
|
|
|
multi organism behavior
|
GO:0051705 |
175 |
0.054
|
|
|
|
chromatin organization
|
GO:0006325 |
207 |
0.053
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
190 |
0.052
|
|
|
|
autophagic vacuole assembly
|
GO:0000045 |
2 |
0.052
|
|
|
|
regulation of post embryonic development
|
GO:0048580 |
10 |
0.052
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
171 |
0.051
|
|
|
|
stem cell proliferation
|
GO:0072089 |
88 |
0.050
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
45 |
0.050
|
|
|
|
lateral inhibition
|
GO:0046331 |
206 |
0.050
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
51 |
0.050
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
31 |
0.050
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
41 |
0.049
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
24 |
0.049
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
261 |
0.049
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
90 |
0.049
|
|
|
|
organelle assembly
|
GO:0070925 |
198 |
0.049
|
|
|
|
organelle fission
|
GO:0048285 |
340 |
0.049
|
|
|
|
hemocyte differentiation
|
GO:0042386 |
38 |
0.048
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
220 |
0.048
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
81 |
0.048
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
201 |
0.048
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
10 |
0.048
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
69 |
0.048
|
|
|
|
activation of immune response
|
GO:0002253 |
5 |
0.047
|
Mouse |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
87 |
0.047
|
Mouse |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
73 |
0.047
|
|
|
|
cell migration
|
GO:0016477 |
238 |
0.047
|
Zebrafish |
|
|
g2 dna damage checkpoint
|
GO:0031572 |
69 |
0.047
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
38 |
0.046
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
109 |
0.046
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
210 |
0.046
|
|
|
|
dna metabolic process
|
GO:0006259 |
227 |
0.046
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
103 |
0.046
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
89 |
0.046
|
|
|
|
protein acylation
|
GO:0043543 |
42 |
0.046
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
54 |
0.045
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
88 |
0.045
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
145 |
0.045
|
|
|
|
regulation of hemocyte differentiation
|
GO:0045610 |
22 |
0.045
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
10 |
0.045
|
|
|
|
maintenance of location
|
GO:0051235 |
73 |
0.044
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
119 |
0.044
|
|
|
|
lipid storage
|
GO:0019915 |
38 |
0.044
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
1 |
0.043
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
58 |
0.043
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
1 |
0.043
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
185 |
0.043
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.042
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
103 |
0.042
|
|
|
|
chromatin remodeling
|
GO:0006338 |
72 |
0.042
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
94 |
0.042
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
49 |
0.042
|
|
|
|
endocytosis
|
GO:0006897 |
310 |
0.042
|
Mouse Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
34 |
0.041
|
Mouse |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
38 |
0.041
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
58 |
0.041
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
109 |
0.041
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
78 |
0.041
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
122 |
0.041
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
18 |
0.041
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.040
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
15 |
0.040
|
|
|
|
death
|
GO:0016265 |
284 |
0.040
|
Mouse |
|
|
neuroblast division
|
GO:0055057 |
35 |
0.040
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
39 |
0.040
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
163 |
0.039
|
|
|
|
tor signaling
|
GO:0031929 |
32 |
0.039
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.039
|
Mouse |
|
|
tube morphogenesis
|
GO:0035239 |
191 |
0.039
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
250 |
0.039
|
Mouse |
|
|
reproductive system development
|
GO:0061458 |
74 |
0.039
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
270 |
0.039
|
|
|
|
translation
|
GO:0006412 |
69 |
0.039
|
|
|
|
tissue migration
|
GO:0090130 |
155 |
0.038
|
|
|
|
regulation of antifungal peptide biosynthetic process
|
GO:0002810 |
5 |
0.038
|
|
|
|
stem cell division
|
GO:0017145 |
69 |
0.038
|
|
|
|
regulation of autophagy
|
GO:0010506 |
62 |
0.038
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
42 |
0.038
|
|
|
|
gastrulation
|
GO:0007369 |
70 |
0.038
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
3 |
0.037
|
|
|
|
negative regulation of cellular response to oxidative stress
|
GO:1900408 |
1 |
0.037
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
145 |
0.037
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
2 |
0.036
|
|
|
|
multicellular organism growth
|
GO:0035264 |
46 |
0.036
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
28 |
0.036
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
266 |
0.035
|
|
|
|
immune effector process
|
GO:0002252 |
98 |
0.035
|
|
|
|
cellular catabolic process
|
GO:0044248 |
372 |
0.035
|
|
|
|
cell growth
|
GO:0016049 |
108 |
0.034
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
223 |
0.034
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
170 |
0.034
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
44 |
0.034
|
|
|
|
negative regulation of notch signaling pathway
|
GO:0045746 |
41 |
0.034
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
118 |
0.034
|
|
|
|
oocyte microtubule cytoskeleton polarization
|
GO:0008103 |
22 |
0.033
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
22 |
0.033
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
3 |
0.033
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
23 |
0.033
|
|
|
|
cell fate specification
|
GO:0001708 |
71 |
0.033
|
|
|
|
apoptotic process
|
GO:0006915 |
159 |
0.033
|
Mouse |
|
|
regulation of neurogenesis
|
GO:0050767 |
158 |
0.033
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
42 |
0.033
|
|
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.033
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.033
|
|
|
|
production of small rna involved in gene silencing by rna
|
GO:0070918 |
15 |
0.032
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
43 |
0.032
|
|
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
1 |
0.032
|
|
|
|
antifungal peptide biosynthetic process
|
GO:0002783 |
5 |
0.032
|
|
|
|
segmentation
|
GO:0035282 |
207 |
0.032
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
89 |
0.032
|
|
|
|
programmed cell death
|
GO:0012501 |
257 |
0.031
|
Mouse |
|
|
histone modification
|
GO:0016570 |
106 |
0.031
|
|
|
|
compound eye photoreceptor development
|
GO:0042051 |
78 |
0.031
|
|
|
|
regulation of decapentaplegic signaling pathway
|
GO:0090097 |
8 |
0.031
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
16 |
0.031
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
139 |
0.031
|
Mouse |
|
|
sensory organ morphogenesis
|
GO:0090596 |
260 |
0.031
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
52 |
0.030
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
108 |
0.030
|
|
|
|
endoderm formation
|
GO:0001706 |
3 |
0.030
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
98 |
0.030
|
|
|
|
oocyte differentiation
|
GO:0009994 |
145 |
0.030
|
|
|
|
myotube cell development
|
GO:0014904 |
3 |
0.030
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
88 |
0.030
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
66 |
0.030
|
|
|
|
sex differentiation
|
GO:0007548 |
81 |
0.030
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
32 |
0.029
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
21 |
0.029
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
196 |
0.029
|
|
|
|
regulation of photoreceptor cell differentiation
|
GO:0046532 |
34 |
0.029
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
4 |
0.029
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
165 |
0.029
|
|
|
|
regulation of transport
|
GO:0051049 |
181 |
0.029
|
Mouse |
|
|
protein localization
|
GO:0008104 |
284 |
0.029
|
|
|
|
parallel actin filament bundle assembly
|
GO:0030046 |
2 |
0.028
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
23 |
0.028
|
|
|
|
mitochondrion organization
|
GO:0007005 |
65 |
0.028
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
1 |
0.028
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
138 |
0.028
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
18 |
0.028
|
|
|
|
stem cell maintenance
|
GO:0019827 |
67 |
0.028
|
|
|
|
cellular homeostasis
|
GO:0019725 |
80 |
0.028
|
Mouse |
|
|
photoreceptor cell development
|
GO:0042461 |
96 |
0.028
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
316 |
0.027
|
|
|
|
response to osmotic stress
|
GO:0006970 |
14 |
0.027
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
4 |
0.027
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
42 |
0.027
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
39 |
0.027
|
Mouse |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
210 |
0.027
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.027
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
251 |
0.027
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
2 |
0.027
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
24 |
0.027
|
|
|
|
response to x ray
|
GO:0010165 |
8 |
0.027
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
236 |
0.027
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.026
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
119 |
0.026
|
|
|
|
response to peptide hormone
|
GO:0043434 |
29 |
0.026
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
161 |
0.026
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
65 |
0.026
|
|
|
|
response to hypoxia
|
GO:0001666 |
53 |
0.026
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
54 |
0.025
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
63 |
0.025
|
Mouse |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
103 |
0.025
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
130 |
0.025
|
|
|
|
regulation of nurse cell apoptotic process
|
GO:0045477 |
9 |
0.025
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
70 |
0.025
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
62 |
0.025
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
35 |
0.024
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
133 |
0.024
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
40 |
0.024
|
|
|
|
negative regulation of protein tyrosine kinase activity
|
GO:0061099 |
5 |
0.024
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
39 |
0.023
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
51 |
0.023
|
|
|
|
embryonic organ development
|
GO:0048568 |
50 |
0.023
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
33 |
0.023
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
3 |
0.023
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
112 |
0.023
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
27 |
0.023
|
Mouse |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
265 |
0.023
|
|
|
|
dephosphorylation
|
GO:0016311 |
51 |
0.023
|
|
|
|
cellular response to hexose stimulus
|
GO:0071331 |
1 |
0.022
|
Mouse |
|
|
compound eye development
|
GO:0048749 |
307 |
0.022
|
|
|
|
decapentaplegic signaling pathway
|
GO:0008101 |
19 |
0.022
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
89 |
0.022
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
143 |
0.022
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
92 |
0.022
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.021
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
105 |
0.021
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
7 |
0.021
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
34 |
0.021
|
|
|
|
chromatin modification
|
GO:0016568 |
147 |
0.021
|
|
|
|
chitin based cuticle development
|
GO:0040003 |
49 |
0.021
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
37 |
0.021
|
|
|
|
response to glucose
|
GO:0009749 |
2 |
0.021
|
Mouse |
|
|
negative regulation of kinase activity
|
GO:0033673 |
16 |
0.021
|
|
|
|
membrane invagination
|
GO:0010324 |
11 |
0.021
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
151 |
0.020
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
35 |
0.020
|
|
|
|
negative regulation of developmental growth
|
GO:0048640 |
64 |
0.020
|
|
|
|
kidney development
|
GO:0001822 |
3 |
0.020
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
38 |
0.020
|
|
|
|
protein complex localization
|
GO:0031503 |
4 |
0.020
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
74 |
0.020
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
45 |
0.020
|
|
|
|
ion homeostasis
|
GO:0050801 |
55 |
0.020
|
|
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
28 |
0.019
|
Zebrafish |
|
|
regulation of jnk cascade
|
GO:0046328 |
40 |
0.019
|
|
|
|
autophagy
|
GO:0006914 |
108 |
0.019
|
|
|
|
regulation of translation
|
GO:0006417 |
56 |
0.019
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
116 |
0.019
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
8 |
0.019
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
81 |
0.019
|
|
|
|
cuticle pigmentation
|
GO:0048067 |
22 |
0.019
|
|
|
|
protein deubiquitination
|
GO:0016579 |
17 |
0.019
|
|
|
|
protein complex assembly
|
GO:0006461 |
200 |
0.019
|
|
|
|
embryonic axis specification
|
GO:0000578 |
107 |
0.019
|
|
|
|
cellular response to peptide
|
GO:1901653 |
28 |
0.019
|
|
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
67 |
0.019
|
|
|
|
actin filament based process
|
GO:0030029 |
220 |
0.019
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
6 |
0.019
|
|
|
|
response to organophosphorus
|
GO:0046683 |
2 |
0.019
|
|
|
|
dna replication
|
GO:0006260 |
48 |
0.019
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
136 |
0.018
|
Mouse |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
138 |
0.018
|
|
|
|
regulation of mitosis
|
GO:0007088 |
56 |
0.018
|
|
|
|
histone acetylation
|
GO:0016573 |
38 |
0.018
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
81 |
0.018
|
Mouse |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
4 |
0.018
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
119 |
0.018
|
|
|
|
multicellular organismal reproductive behavior
|
GO:0033057 |
110 |
0.018
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
58 |
0.018
|
|
|
|
cilium organization
|
GO:0044782 |
41 |
0.018
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
68 |
0.018
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
58 |
0.018
|
|
|
|
chromosome segregation
|
GO:0007059 |
157 |
0.018
|
|
|
|
chitin based embryonic cuticle biosynthetic process
|
GO:0008362 |
16 |
0.018
|
|
|
|
imaginal disc pattern formation
|
GO:0007447 |
91 |
0.018
|
|
