Drosophila melanogaster

28 known processes

Sb (Dmel_CG4316)

Stubble

(Aliases: st-sb,c-SP56,Sb-sbd,Dmel\CG4316,CG4316,sbd,SP56)

Sb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament organization GO:0007015 126 0.168
actin filament based process GO:0030029 220 0.159
actin cytoskeleton organization GO:0030036 206 0.121
appendage development GO:0048736 401 0.099
epithelial cell differentiation GO:0030855 322 0.092
regulation of anatomical structure morphogenesis GO:0022603 242 0.084
epithelial cell development GO:0002064 274 0.082
dendrite development GO:0016358 204 0.075
regulation of cell shape GO:0008360 113 0.074
imaginal disc derived appendage morphogenesis GO:0035114 395 0.073
post embryonic appendage morphogenesis GO:0035120 385 0.070
regulation of multicellular organismal development GO:2000026 414 0.068
regulation of cell morphogenesis GO:0022604 163 0.064
biological adhesion GO:0022610 138 0.063
cell adhesion GO:0007155 136 0.062
wing disc morphogenesis GO:0007472 344 0.060
imaginal disc derived appendage development GO:0048737 399 0.059
appendage morphogenesis GO:0035107 397 0.053
pigment metabolic process involved in pigmentation GO:0043474 33 0.050
vesicle mediated transport GO:0016192 381 0.048
imaginal disc derived wing morphogenesis GO:0007476 337 0.044
actin filament based movement GO:0030048 26 0.044
regulation of embryonic development GO:0045995 68 0.043
organonitrogen compound metabolic process GO:1901564 318 0.041
cellular amino acid metabolic process GO:0006520 61 0.037
dendrite morphogenesis GO:0048813 199 0.035
positive regulation of response to stimulus GO:0048584 323 0.035
developmental pigmentation GO:0048066 68 0.035
neurological system process GO:0050877 358 0.035
actin mediated cell contraction GO:0070252 21 0.034
positive regulation of rna biosynthetic process GO:1902680 266 0.034
small molecule metabolic process GO:0044281 305 0.033
positive regulation of signal transduction GO:0009967 223 0.032
immune system process GO:0002376 347 0.032
defense response GO:0006952 300 0.032
regulation of embryonic cell shape GO:0016476 30 0.032
response to organic substance GO:0010033 284 0.030
negative regulation of cellular metabolic process GO:0031324 382 0.030
response to light stimulus GO:0009416 124 0.029
triglyceride biosynthetic process GO:0019432 2 0.029
cellular protein modification process GO:0006464 438 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.028
segmentation GO:0035282 207 0.028
apical constriction GO:0003383 18 0.028
death GO:0016265 284 0.027
response to abiotic stimulus GO:0009628 341 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
carboxylic acid metabolic process GO:0019752 92 0.027
kidney development GO:0001822 3 0.027
phagocytosis GO:0006909 215 0.027
response to biotic stimulus GO:0009607 294 0.027
protein modification process GO:0036211 438 0.026
eye pigmentation GO:0048069 43 0.026
response to radiation GO:0009314 155 0.026
cell death GO:0008219 279 0.026
taxis GO:0042330 304 0.025
response to lipopolysaccharide GO:0032496 4 0.025
gland development GO:0048732 191 0.025
body morphogenesis GO:0010171 2 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.025
autophagic cell death GO:0048102 83 0.025
response to external biotic stimulus GO:0043207 293 0.025
positive regulation of macromolecule metabolic process GO:0010604 405 0.024
organic acid metabolic process GO:0006082 103 0.024
endocytosis GO:0006897 310 0.024
single organism biosynthetic process GO:0044711 206 0.024
phosphorylation GO:0016310 294 0.024
positive regulation of cell communication GO:0010647 250 0.024
regulation of immune system process GO:0002682 176 0.024
pigmentation GO:0043473 75 0.024
response to other organism GO:0051707 293 0.024
open tracheal system development GO:0007424 204 0.024
pigment metabolic process GO:0042440 84 0.024
developmental programmed cell death GO:0010623 138 0.023
cellular modified amino acid metabolic process GO:0006575 45 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
camera type eye development GO:0043010 4 0.023
detection of abiotic stimulus GO:0009582 66 0.023
sensory perception of sound GO:0007605 56 0.023
organic substance transport GO:0071702 257 0.023
transcription from rna polymerase ii promoter GO:0006366 368 0.023
positive regulation of rna metabolic process GO:0051254 271 0.022
salivary gland development GO:0007431 162 0.022
response to oxygen containing compound GO:1901700 200 0.022
catabolic process GO:0009056 409 0.022
oxoacid metabolic process GO:0043436 103 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
regulation of molecular function GO:0065009 217 0.022
sensory perception GO:0007600 196 0.022
regulation of cell differentiation GO:0045595 302 0.021
regulation of localization GO:0032879 275 0.021
ethanolamine containing compound metabolic process GO:0042439 4 0.021
respiratory system development GO:0060541 213 0.021
anion homeostasis GO:0055081 3 0.021
regulation of multi organism process GO:0043900 131 0.021
lateral inhibition GO:0046331 206 0.021
negative regulation of cellular biosynthetic process GO:0031327 277 0.021
regionalization GO:0003002 416 0.020
eye development GO:0001654 323 0.020
organic substance catabolic process GO:1901575 308 0.020
programmed cell death GO:0012501 257 0.020
negative regulation of gene expression GO:0010629 387 0.020
negative regulation of biosynthetic process GO:0009890 277 0.020
gland morphogenesis GO:0022612 145 0.020
positive regulation of nucleic acid templated transcription GO:1903508 266 0.020
cholesterol homeostasis GO:0042632 3 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
digestive tract development GO:0048565 149 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
regulation of protein metabolic process GO:0051246 256 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
neutral lipid biosynthetic process GO:0046460 2 0.019
positive regulation of signaling GO:0023056 243 0.019
tissue death GO:0016271 102 0.019
regulation of catalytic activity GO:0050790 185 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
morphogenesis of an epithelium GO:0002009 276 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
cellular ketone metabolic process GO:0042180 24 0.018
cellular amine metabolic process GO:0044106 12 0.018
humoral immune response GO:0006959 117 0.018
single organism catabolic process GO:0044712 228 0.018
cellular response to lipopolysaccharide GO:0071222 3 0.018
positive regulation of gene expression GO:0010628 290 0.018
defense response to other organism GO:0098542 225 0.018
chemotaxis GO:0006935 249 0.018
immune response GO:0006955 246 0.018
acylglycerol biosynthetic process GO:0046463 2 0.018
regulation of transport GO:0051049 181 0.018
histolysis GO:0007559 102 0.018
defense response to bacterium GO:0042742 178 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
negative regulation of rna metabolic process GO:0051253 251 0.018
positive regulation of cell motility GO:2000147 3 0.018
response to copper ion GO:0046688 4 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.017
positive regulation of cell migration GO:0030335 2 0.017
amine metabolic process GO:0009308 12 0.017
salivary gland morphogenesis GO:0007435 145 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
tube development GO:0035295 244 0.017
sensory organ morphogenesis GO:0090596 260 0.017
blastoderm segmentation GO:0007350 159 0.017
cholesterol transport GO:0030301 2 0.017
gene silencing GO:0016458 138 0.017
immune response activating signal transduction GO:0002757 2 0.017
compound eye development GO:0048749 307 0.016
intracellular signal transduction GO:0035556 300 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
establishment of localization in cell GO:0051649 402 0.016
leg disc morphogenesis GO:0007478 80 0.016
imaginal disc derived leg morphogenesis GO:0007480 80 0.016
phospholipid homeostasis GO:0055091 1 0.016
axis specification GO:0009798 167 0.016
antimicrobial humoral response GO:0019730 99 0.016
actin filament bundle assembly GO:0051017 26 0.016
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.016
cell proliferation GO:0008283 299 0.016
tube morphogenesis GO:0035239 191 0.016
exocrine system development GO:0035272 162 0.016
embryonic pattern specification GO:0009880 174 0.016
negative regulation of signal transduction GO:0009968 206 0.016
regulation of response to stress GO:0080134 200 0.016
salivary gland histolysis GO:0035070 88 0.015
protein transport GO:0015031 155 0.015
sterol homeostasis GO:0055092 4 0.015
anterior posterior pattern specification GO:0009952 136 0.015
triglyceride catabolic process GO:0019433 3 0.015
macromolecular complex assembly GO:0065003 256 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
eye pigment metabolic process GO:0042441 33 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
carbohydrate derivative biosynthetic process GO:1901137 85 0.015
connective tissue development GO:0061448 3 0.015
leg disc development GO:0035218 92 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
cellular amide metabolic process GO:0043603 80 0.015
cellular response to organic substance GO:0071310 132 0.014
response to bacterium GO:0009617 198 0.014
hindbrain development GO:0030902 2 0.014
negative regulation of signaling GO:0023057 219 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
eye morphogenesis GO:0048592 260 0.014
cell migration GO:0016477 238 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
cell motility GO:0048870 251 0.014
immune effector process GO:0002252 98 0.014
embryonic axis specification GO:0000578 107 0.014
gene silencing by rna GO:0031047 57 0.014
tripartite regional subdivision GO:0007351 103 0.014
glycerolipid catabolic process GO:0046503 3 0.014
macromolecule catabolic process GO:0009057 161 0.014
regulation of cell death GO:0010941 173 0.014
negative regulation of cell communication GO:0010648 223 0.014
forebrain development GO:0030900 2 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
phosphatidylethanolamine metabolic process GO:0046337 1 0.014
cellular catabolic process GO:0044248 372 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.014
protein complex assembly GO:0006461 200 0.014
regulation of immune response GO:0050776 118 0.014
detection of stimulus GO:0051606 156 0.014
phenol containing compound metabolic process GO:0018958 57 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
protein localization GO:0008104 284 0.014
embryonic morphogenesis GO:0048598 206 0.014
regulation of humoral immune response GO:0002920 51 0.014
homeostatic process GO:0042592 199 0.014
telencephalon development GO:0021537 2 0.014
organophosphate metabolic process GO:0019637 195 0.013
chaeta development GO:0022416 97 0.013
negative regulation of developmental process GO:0051093 201 0.013
localization of cell GO:0051674 257 0.013
axon development GO:0061564 297 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
organic hydroxy compound metabolic process GO:1901615 83 0.013
regulation of cell cycle GO:0051726 291 0.013
organelle fission GO:0048285 340 0.013
regulation of cell cycle process GO:0010564 181 0.013
cell division GO:0051301 248 0.013
protein complex biogenesis GO:0070271 201 0.013
single organism behavior GO:0044708 391 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
nephron development GO:0072006 3 0.013
regulation of sequestering of triglyceride GO:0010889 3 0.013
phosphatidic acid metabolic process GO:0046473 1 0.013
regulation of lipid transport GO:0032368 3 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
positive regulation of sequestering of triglyceride GO:0010890 1 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
response to organophosphorus GO:0046683 2 0.013
rna localization GO:0006403 115 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
anterior posterior axis specification GO:0009948 109 0.013
innate immune response activating signal transduction GO:0002758 2 0.013
actin filament bundle organization GO:0061572 28 0.012
sulfur compound metabolic process GO:0006790 59 0.012
regulation of programmed cell death GO:0043067 152 0.012
regulation of anatomical structure size GO:0090066 163 0.012
intracellular transport GO:0046907 228 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
innate immune response GO:0045087 144 0.012
digestive system development GO:0055123 149 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
ras protein signal transduction GO:0007265 88 0.012
tissue migration GO:0090130 155 0.012
regulation of cell development GO:0060284 215 0.012
regulation of response to external stimulus GO:0032101 115 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
establishment of protein localization GO:0045184 163 0.012
cell substrate adhesion GO:0031589 10 0.012
regulation of gene silencing GO:0060968 63 0.012
positive regulation of immune system process GO:0002684 68 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
ommochrome metabolic process GO:0046152 19 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
single organism cellular localization GO:1902580 180 0.012
positive regulation of molecular function GO:0044093 136 0.012
digestive tract morphogenesis GO:0048546 127 0.012
compound eye morphogenesis GO:0001745 249 0.012
proteolysis GO:0006508 192 0.012
developmental maturation GO:0021700 172 0.012
androgen metabolic process GO:0008209 1 0.012
regulation of response to biotic stimulus GO:0002831 63 0.012
regulation of cell proliferation GO:0042127 163 0.012
cellular protein localization GO:0034613 160 0.012
regulation of phosphorylation GO:0042325 147 0.012
tissue morphogenesis GO:0048729 297 0.012
organophosphate catabolic process GO:0046434 112 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
developmental growth GO:0048589 280 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
positive regulation of developmental process GO:0051094 143 0.011
limb development GO:0060173 1 0.011
notch signaling pathway GO:0007219 120 0.011
regulation of sterol transport GO:0032371 1 0.011
morphogenesis of embryonic epithelium GO:0016331 94 0.011
cellular lipid metabolic process GO:0044255 83 0.011
mesenchymal cell development GO:0014031 1 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
single organism intracellular transport GO:1902582 207 0.011
hindgut morphogenesis GO:0007442 58 0.011
pattern recognition receptor signaling pathway GO:0002221 2 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
chromosome organization GO:0051276 360 0.011
axonogenesis GO:0007409 290 0.011
neutral lipid catabolic process GO:0046461 3 0.011
regulation of cellular amide metabolic process GO:0034248 39 0.011
cuticle development GO:0042335 86 0.011
pigment biosynthetic process GO:0046148 36 0.011
determination of adult lifespan GO:0008340 137 0.011
nuclear division GO:0000280 332 0.011
protein phosphorylation GO:0006468 169 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
retina development in camera type eye GO:0060041 4 0.011
apoptotic process GO:0006915 159 0.011
stem cell differentiation GO:0048863 117 0.011
positive regulation of cell death GO:0010942 69 0.011
mitotic nuclear division GO:0007067 213 0.011
neuron projection guidance GO:0097485 241 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
eye pigment biosynthetic process GO:0006726 32 0.011
limb morphogenesis GO:0035108 1 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
cellular macromolecule localization GO:0070727 220 0.011
response to temperature stimulus GO:0009266 106 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
ovarian follicle cell development GO:0030707 248 0.011
ameboidal type cell migration GO:0001667 151 0.011
cell maturation GO:0048469 144 0.011
response to monosaccharide GO:0034284 4 0.011
lipid metabolic process GO:0006629 121 0.010
negative regulation of response to stimulus GO:0048585 258 0.010
cellular response to oxygen containing compound GO:1901701 79 0.010
multicellular organismal aging GO:0010259 140 0.010
maintenance of location GO:0051235 73 0.010
alditol phosphate metabolic process GO:0052646 2 0.010
positive regulation of immune response GO:0050778 63 0.010
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010

Sb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.021
nervous system disease DOID:863 0 0.020
acquired metabolic disease DOID:0060158 0 0.018
carbohydrate metabolism disease DOID:0050013 0 0.018
glucose metabolism disease DOID:4194 0 0.018
hair disease DOID:421 0 0.016
hypotrichosis DOID:4535 0 0.016
integumentary system disease DOID:16 0 0.016
familial hyperlipidemia DOID:1168 0 0.015
lipid metabolism disorder DOID:3146 0 0.015
familial lipoprotein lipase deficiency DOID:14118 0 0.015
diabetes mellitus DOID:9351 0 0.014
type 2 diabetes mellitus DOID:9352 0 0.014
familial hypertriglyceridemia DOID:0050527 0 0.013
familial combined hyperlipidemia DOID:13809 0 0.013
disease of cellular proliferation DOID:14566 0 0.011
musculoskeletal system disease DOID:17 0 0.011
sensory system disease DOID:0050155 0 0.010