Drosophila melanogaster

25 known processes

Hmgs (Dmel_CG4311)

HMG Coenzyme A synthase

(Aliases: Ov25,CG4311,Dmel\CG4311,CG16796,l(2)06214)

Hmgs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of gene expression GO:0010628 290 0.177
carboxylic acid metabolic process GO:0019752 92 0.174
small molecule metabolic process GO:0044281 305 0.139
organonitrogen compound metabolic process GO:1901564 318 0.110
response to abiotic stimulus GO:0009628 341 0.104
organic hydroxy compound metabolic process GO:1901615 83 0.102
negative regulation of cellular biosynthetic process GO:0031327 277 0.098
organic acid metabolic process GO:0006082 103 0.095
oxoacid metabolic process GO:0043436 103 0.091
positive regulation of transcription dna templated GO:0045893 266 0.091
negative regulation of cellular metabolic process GO:0031324 382 0.087
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.085
positive regulation of rna metabolic process GO:0051254 271 0.085
positive regulation of nucleic acid templated transcription GO:1903508 266 0.084
ion homeostasis GO:0050801 55 0.084
cellular amine metabolic process GO:0044106 12 0.082
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.082
head development GO:0060322 135 0.080
l glutamate import GO:0051938 1 0.079
nuclear division GO:0000280 332 0.078
immune response GO:0006955 246 0.077
organic substance transport GO:0071702 257 0.077
embryo development ending in birth or egg hatching GO:0009792 152 0.073
spindle organization GO:0007051 253 0.071
endocytosis GO:0006897 310 0.070
positive regulation of rna biosynthetic process GO:1902680 266 0.068
alpha amino acid metabolic process GO:1901605 20 0.068
organelle fission GO:0048285 340 0.066
cellular amino acid metabolic process GO:0006520 61 0.065
protein transport GO:0015031 155 0.064
cellular lipid metabolic process GO:0044255 83 0.063
cellular response to chemical stimulus GO:0070887 199 0.062
negative regulation of transcription dna templated GO:0045892 237 0.061
positive regulation of macromolecule metabolic process GO:0010604 405 0.061
negative regulation of nucleic acid templated transcription GO:1903507 240 0.060
negative regulation of biosynthetic process GO:0009890 277 0.060
regulation of protein metabolic process GO:0051246 256 0.060
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.059
segmentation GO:0035282 207 0.059
growth GO:0040007 359 0.056
organic substance catabolic process GO:1901575 308 0.056
mitotic spindle organization GO:0007052 220 0.055
mitotic nuclear division GO:0007067 213 0.055
catabolic process GO:0009056 409 0.054
cellular response to nutrient levels GO:0031669 62 0.053
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.053
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.052
neuron recognition GO:0008038 101 0.052
homeostatic process GO:0042592 199 0.051
cellular response to extracellular stimulus GO:0031668 64 0.050
positive regulation of cellular biosynthetic process GO:0031328 316 0.049
intracellular protein transport GO:0006886 104 0.049
protein localization GO:0008104 284 0.048
establishment of protein localization GO:0045184 163 0.048
sterol homeostasis GO:0055092 4 0.047
protein secretion GO:0009306 45 0.046
vesicle mediated transport GO:0016192 381 0.046
body morphogenesis GO:0010171 2 0.045
negative regulation of gene expression GO:0010629 387 0.045
protein targeting GO:0006605 64 0.045
single organism intracellular transport GO:1902582 207 0.044
response to extracellular stimulus GO:0009991 116 0.043
immune system process GO:0002376 347 0.041
positive regulation of biosynthetic process GO:0009891 316 0.040
response to wounding GO:0009611 94 0.040
camera type eye development GO:0043010 4 0.039
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.039
cell proliferation GO:0008283 299 0.039
phagocytosis GO:0006909 215 0.039
cellular catabolic process GO:0044248 372 0.038
single organism cellular localization GO:1902580 180 0.038
phosphatidylinositol mediated signaling GO:0048015 4 0.038
cellular response to external stimulus GO:0071496 66 0.037
cytoplasmic transport GO:0016482 130 0.035
defense response to other organism GO:0098542 225 0.035
negative regulation of rna biosynthetic process GO:1902679 240 0.034
response to organic substance GO:0010033 284 0.034
lipid metabolic process GO:0006629 121 0.034
response to temperature stimulus GO:0009266 106 0.034
negative regulation of mitotic cell cycle GO:0045930 109 0.034
protein maturation GO:0051604 71 0.033
regulation of protein transport GO:0051223 57 0.033
defense response to bacterium GO:0042742 178 0.032
phototaxis GO:0042331 21 0.032
amine metabolic process GO:0009308 12 0.032
single organism catabolic process GO:0044712 228 0.032
protein modification process GO:0036211 438 0.031
regulation of immune system process GO:0002682 176 0.031
establishment of localization in cell GO:0051649 402 0.031
male gamete generation GO:0048232 201 0.030
regulation of cellular protein metabolic process GO:0032268 243 0.030
central nervous system development GO:0007417 201 0.030
regulation of growth GO:0040008 233 0.030
cholesterol homeostasis GO:0042632 3 0.030
cellular macromolecule localization GO:0070727 220 0.029
regulation of developmental growth GO:0048638 174 0.029
axonogenesis GO:0007409 290 0.028
regulation of molecular function GO:0065009 217 0.028
negative regulation of rna metabolic process GO:0051253 251 0.028
androgen metabolic process GO:0008209 1 0.028
actin cytoskeleton organization GO:0030036 206 0.028
positive regulation of immune system process GO:0002684 68 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.027
cell death GO:0008219 279 0.026
death GO:0016265 284 0.026
trna aminoacylation GO:0043039 2 0.025
gonad development GO:0008406 50 0.025
regulation of anatomical structure morphogenesis GO:0022603 242 0.025
dendrite development GO:0016358 204 0.025
regionalization GO:0003002 416 0.024
anion homeostasis GO:0055081 3 0.024
positive regulation of cell motility GO:2000147 3 0.024
regulation of protein deacetylation GO:0090311 2 0.024
kidney development GO:0001822 3 0.024
organelle assembly GO:0070925 198 0.024
response to external biotic stimulus GO:0043207 293 0.023
autophagic vacuole assembly GO:0000045 2 0.023
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
sodium dependent phosphate transport GO:0044341 2 0.023
cellular protein modification process GO:0006464 438 0.023
positive regulation of protein transport GO:0051222 37 0.023
tube development GO:0035295 244 0.023
negative regulation of growth GO:0045926 84 0.023
regulation of cell proliferation GO:0042127 163 0.023
positive regulation of cell migration GO:0030335 2 0.022
regulation of cell projection organization GO:0031344 92 0.022
larval development GO:0002164 104 0.022
regulation of lipid transport GO:0032368 3 0.022
regulation of catalytic activity GO:0050790 185 0.022
vacuolar transport GO:0007034 13 0.022
nucleocytoplasmic transport GO:0006913 72 0.022
organophosphate metabolic process GO:0019637 195 0.021
cellular protein localization GO:0034613 160 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
organelle fusion GO:0048284 46 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
axon development GO:0061564 297 0.021
imaginal disc pattern formation GO:0007447 91 0.021
peripheral nervous system development GO:0007422 52 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
gland development GO:0048732 191 0.021
response to oxygen containing compound GO:1901700 200 0.021
reproductive system development GO:0061458 74 0.021
small molecule biosynthetic process GO:0044283 37 0.021
cellular response to endogenous stimulus GO:0071495 80 0.020
regulation of nervous system development GO:0051960 248 0.020
mushroom body development GO:0016319 70 0.020
skeletal muscle fiber development GO:0048741 3 0.020
negative regulation of epithelial cell proliferation GO:0050680 4 0.020
response to decreased oxygen levels GO:0036293 58 0.020
defense response to gram negative bacterium GO:0050829 94 0.020
positive regulation of multi organism process GO:0043902 40 0.020
gene silencing GO:0016458 138 0.020
inositol lipid mediated signaling GO:0048017 4 0.020
reproductive structure development GO:0048608 74 0.019
macroautophagy GO:0016236 42 0.019
wing disc pattern formation GO:0035222 66 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
cellular protein complex assembly GO:0043623 71 0.019
regulation of proteolysis GO:0030162 87 0.019
defense response GO:0006952 300 0.019
programmed cell death GO:0012501 257 0.019
protein localization to nucleus GO:0034504 55 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
positive regulation of cell communication GO:0010647 250 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
cellular ketone metabolic process GO:0042180 24 0.019
single organism membrane organization GO:0044802 93 0.019
positive regulation of response to external stimulus GO:0032103 44 0.018
chemical homeostasis GO:0048878 92 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
embryonic development via the syncytial blastoderm GO:0001700 148 0.018
regulation of neurogenesis GO:0050767 158 0.018
neuromuscular synaptic transmission GO:0007274 67 0.018
positive regulation of apoptotic signaling pathway GO:2001235 4 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
negative regulation of signal transduction GO:0009968 206 0.018
neurological system process GO:0050877 358 0.018
regulation of protein localization GO:0032880 76 0.018
protein localization to organelle GO:0033365 82 0.017
spermatogenesis GO:0007283 200 0.017
microtubule organizing center organization GO:0031023 168 0.017
retina development in camera type eye GO:0060041 4 0.017
positive regulation of signal transduction GO:0009967 223 0.017
regulation of phosphorylation GO:0042325 147 0.017
embryonic morphogenesis GO:0048598 206 0.017
single organism membrane fusion GO:0044801 42 0.017
regulation of membrane potential GO:0042391 35 0.017
somatic stem cell division GO:0048103 37 0.016
positive regulation of cell death GO:0010942 69 0.016
secretion by cell GO:0032940 101 0.016
protein import into nucleus GO:0006606 51 0.016
phosphate ion transport GO:0006817 4 0.016
positive regulation of lipid metabolic process GO:0045834 4 0.016
macromolecule catabolic process GO:0009057 161 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
neuronal action potential GO:0019228 10 0.016
establishment of blood nerve barrier GO:0008065 2 0.016
ensheathment of neurons GO:0007272 10 0.016
regulation of immune effector process GO:0002697 52 0.015
endomembrane system organization GO:0010256 119 0.015
positive regulation of signaling GO:0023056 243 0.015
nuclear import GO:0051170 51 0.015
myotube cell development GO:0014904 3 0.015
developmental growth GO:0048589 280 0.015
response to other organism GO:0051707 293 0.015
single organism nuclear import GO:1902593 51 0.015
vitamin metabolic process GO:0006766 2 0.015
lipid catabolic process GO:0016042 21 0.015
developmental maturation GO:0021700 172 0.015
respiratory system development GO:0060541 213 0.015
macromolecular complex assembly GO:0065003 256 0.015
protein processing GO:0016485 68 0.015
taxis GO:0042330 304 0.015
kidney epithelium development GO:0072073 3 0.014
action potential GO:0001508 13 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
forebrain development GO:0030900 2 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
brain development GO:0007420 120 0.014
connective tissue development GO:0061448 3 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
chitin based cuticle development GO:0040003 49 0.014
regulation of cell cycle GO:0051726 291 0.014
protein complex biogenesis GO:0070271 201 0.014
membrane fusion GO:0061025 42 0.014
chaeta development GO:0022416 97 0.014
acylglycerol biosynthetic process GO:0046463 2 0.014
regulation of multi organism process GO:0043900 131 0.014
response to organophosphorus GO:0046683 2 0.014
regulation of epithelial cell proliferation GO:0050678 4 0.014
response to oxygen levels GO:0070482 59 0.013
establishment of protein localization to organelle GO:0072594 62 0.013
protein complex assembly GO:0006461 200 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
lipid biosynthetic process GO:0008610 46 0.013
cation transport GO:0006812 110 0.013
fat soluble vitamin metabolic process GO:0006775 1 0.013
digestive tract morphogenesis GO:0048546 127 0.013
axon guidance GO:0007411 233 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
centrosome cycle GO:0007098 137 0.013
ethanolamine containing compound metabolic process GO:0042439 4 0.013
long chain fatty acid metabolic process GO:0001676 3 0.013
positive regulation of molecular function GO:0044093 136 0.013
regulation of response to external stimulus GO:0032101 115 0.013
response to biotic stimulus GO:0009607 294 0.013
epithelial cell differentiation GO:0030855 322 0.013
positive regulation of protein secretion GO:0050714 9 0.013
regulation of protein import into nucleus GO:0042306 28 0.013
response to bacterium GO:0009617 198 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.013
sex differentiation GO:0007548 81 0.012
eye development GO:0001654 323 0.012
regulation of immune response GO:0050776 118 0.012
phosphatidic acid metabolic process GO:0046473 1 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
steroid metabolic process GO:0008202 20 0.012
nuclear transport GO:0051169 72 0.012
cardiovascular system development GO:0072358 82 0.012
regulation of cell development GO:0060284 215 0.012
protein phosphorylation GO:0006468 169 0.012
dopamine biosynthetic process GO:0042416 3 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
nephron epithelium development GO:0072009 3 0.012
regulation of catabolic process GO:0009894 170 0.012
cell cycle phase transition GO:0044770 140 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
peptidyl threonine phosphorylation GO:0018107 2 0.012
nucleoside metabolic process GO:0009116 127 0.012
response to radiation GO:0009314 155 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
positive regulation of cell development GO:0010720 61 0.012
rna processing GO:0006396 147 0.012
ion transport GO:0006811 145 0.012
intracellular signal transduction GO:0035556 300 0.012
apoptotic process GO:0006915 159 0.012
aromatic compound catabolic process GO:0019439 166 0.012
chemotaxis GO:0006935 249 0.012
positive regulation of transport GO:0051050 92 0.012
purine nucleoside biosynthetic process GO:0042451 3 0.012
immune response activating signal transduction GO:0002757 2 0.012
dna recombination GO:0006310 32 0.012
positive regulation of cell differentiation GO:0045597 64 0.011
stem cell differentiation GO:0048863 117 0.011
sister chromatid segregation GO:0000819 92 0.011
regulation of nucleocytoplasmic transport GO:0046822 35 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.011
circulatory system development GO:0072359 82 0.011
cell recognition GO:0008037 102 0.011
phosphorylation GO:0016310 294 0.011
single organism behavior GO:0044708 391 0.011
regulation of transport GO:0051049 181 0.011
stem cell division GO:0017145 69 0.011
energy taxis GO:0009453 21 0.011
dendrite morphogenesis GO:0048813 199 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
regulation of histone deacetylation GO:0031063 2 0.011
nephron tubule development GO:0072080 3 0.011
mitochondrion organization GO:0007005 65 0.011
response to endogenous stimulus GO:0009719 119 0.011
proteolysis GO:0006508 192 0.011
axon ensheathment GO:0008366 10 0.011
regulation of neuron differentiation GO:0045664 103 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
immune effector process GO:0002252 98 0.011
positive regulation of protein localization to nucleus GO:1900182 21 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
positive regulation of intracellular transport GO:0032388 42 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
positive regulation of organelle organization GO:0010638 65 0.011
multi multicellular organism process GO:0044706 123 0.011
regulation of cellular localization GO:0060341 136 0.011
response to nutrient levels GO:0031667 114 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of cell cycle process GO:0010564 181 0.011
fatty acid metabolic process GO:0006631 20 0.010
positive regulation of growth GO:0045927 75 0.010
protein import GO:0017038 55 0.010
regulation of rna splicing GO:0043484 69 0.010
peptide metabolic process GO:0006518 80 0.010
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
multicellular organismal signaling GO:0035637 12 0.010
positive regulation of protein complex assembly GO:0031334 22 0.010
regulation of localization GO:0032879 275 0.010
regulation of organelle organization GO:0033043 196 0.010
regulation of transferase activity GO:0051338 58 0.010
regulation of cell death GO:0010941 173 0.010
phosphatidylcholine metabolic process GO:0046470 3 0.010
antimicrobial humoral response GO:0019730 99 0.010
interspecies interaction between organisms GO:0044419 16 0.010
regulation of intracellular transport GO:0032386 64 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
regulation of intracellular protein transport GO:0033157 46 0.010
response to hypoxia GO:0001666 53 0.010
regulation of gene silencing GO:0060968 63 0.010
neural precursor cell proliferation GO:0061351 75 0.010

Hmgs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.103
disease of metabolism DOID:0014667 0 0.048
acquired metabolic disease DOID:0060158 0 0.042
carbohydrate metabolism disease DOID:0050013 0 0.036
glucose metabolism disease DOID:4194 0 0.036
diabetes mellitus DOID:9351 0 0.026
type 2 diabetes mellitus DOID:9352 0 0.026
inherited metabolic disorder DOID:655 0 0.026
disease of cellular proliferation DOID:14566 0 0.016
musculoskeletal system disease DOID:17 0 0.016
nervous system disease DOID:863 0 0.013