Drosophila melanogaster

67 known processes

Sema-2a (Dmel_CG4700)

CG4700 gene product from transcript CG4700-RC

(Aliases: sema2a,Sema2a,dSema-II,D-SemaII,sema-2a,Dmel\CG4700,D-Sema2a,SemaII,sema 2a,CT14922,D-Sema-II,112/40,D-Sema II,CG4700,Dsema-II,BcDNA:LD09561,sema II,sema-II,semaII,l(2)03021,D-semaII)

Sema-2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axon guidance GO:0007411 233 1.000
axonogenesis GO:0007409 290 1.000
axon development GO:0061564 297 0.999
neuron recognition GO:0008038 101 0.999
cell recognition GO:0008037 102 0.996
motor neuron axon guidance GO:0008045 58 0.996
Zebrafish Mouse Fly
regulation of axon guidance GO:1902667 10 0.992
Human Mouse Fly
neuron projection guidance GO:0097485 241 0.988
olfactory bulb axon guidance GO:0071678 3 0.985
chemotaxis GO:0006935 249 0.981
regulation of photoreceptor cell axon guidance GO:2000289 5 0.979
Fly
taxis GO:0042330 304 0.974
axonal defasciculation GO:0007414 12 0.952
regulation of cell size GO:0008361 63 0.873
Human Zebrafish Mouse Rat Fly
cell cell signaling involved in cell fate commitment GO:0045168 210 0.873
lateral inhibition GO:0046331 206 0.850
axon extension involved in axon guidance GO:0048846 10 0.841
Human Mouse
regulation of neuron differentiation GO:0045664 103 0.817
Human Zebrafish Mouse Rat Fly
retinal ganglion cell axon guidance GO:0031290 12 0.806
Zebrafish
regulation of axonogenesis GO:0050770 32 0.800
Human Zebrafish Mouse Rat Fly
regulation of axon extension involved in axon guidance GO:0048841 4 0.766
Human Mouse
developmental growth GO:0048589 280 0.748
Human Zebrafish Mouse Rat
central nervous system development GO:0007417 201 0.744
Human Zebrafish Mouse Fly
cell death GO:0008219 279 0.721
Rat
regulation of cell morphogenesis GO:0022604 163 0.683
Human Zebrafish Mouse Rat Fly
somatic muscle development GO:0007525 66 0.675
axon extension GO:0048675 32 0.603
Human Zebrafish Mouse Rat
tissue morphogenesis GO:0048729 297 0.575
Zebrafish Mouse Worm
regulation of developmental growth GO:0048638 174 0.565
Human Zebrafish Mouse Rat
synapse assembly GO:0007416 143 0.546
Fly
sensory organ morphogenesis GO:0090596 260 0.536
organic acid metabolic process GO:0006082 103 0.508
eye morphogenesis GO:0048592 260 0.443
head development GO:0060322 135 0.433
Human Zebrafish Mouse Fly
regulation of molecular function GO:0065009 217 0.369
Human Mouse
single organism behavior GO:0044708 391 0.365
regulation of neurogenesis GO:0050767 158 0.361
Human Zebrafish Mouse Rat Fly
regulation of cell projection organization GO:0031344 92 0.356
Human Zebrafish Mouse Rat Fly
eye development GO:0001654 323 0.332
regulation of neuron projection development GO:0010975 69 0.326
Human Zebrafish Mouse Rat Fly
appendage development GO:0048736 401 0.318
imaginal disc derived appendage morphogenesis GO:0035114 395 0.314
developmental cell growth GO:0048588 52 0.288
Human Zebrafish Mouse Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.273
Human Zebrafish Mouse Rat Fly
regulation of anatomical structure size GO:0090066 163 0.264
Human Zebrafish Mouse Rat Fly
regulation of nervous system development GO:0051960 248 0.259
Human Zebrafish Mouse Rat Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.248
Human Mouse
wing disc morphogenesis GO:0007472 344 0.241
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.225
Human Mouse
immune response GO:0006955 246 0.222
Mouse
regulation of chemotaxis GO:0050920 12 0.218
Human Mouse Fly
neuron projection extension GO:1990138 32 0.209
Human Zebrafish Mouse Rat
regulation of behavior GO:0050795 75 0.207
Human Mouse Fly
regulation of catalytic activity GO:0050790 185 0.204
Human Mouse
defasciculation of motor neuron axon GO:0007415 8 0.202
regulation of localization GO:0032879 275 0.194
Human Mouse Worm Fly
cell growth GO:0016049 108 0.193
Human Zebrafish Mouse Rat
death GO:0016265 284 0.187
Rat
cell adhesion GO:0007155 136 0.185
Human Worm
developmental growth involved in morphogenesis GO:0060560 65 0.185
Human Zebrafish Mouse Rat
programmed cell death GO:0012501 257 0.183
Rat
response to abiotic stimulus GO:0009628 341 0.173
regulation of growth GO:0040008 233 0.172
Human Zebrafish Mouse Rat
cell motility GO:0048870 251 0.163
Human Zebrafish Mouse Worm
regulation of axon extension GO:0030516 8 0.156
Human Zebrafish Mouse Rat
axon midline choice point recognition GO:0016199 26 0.155
Fly
oxoacid metabolic process GO:0043436 103 0.155
positive regulation of signal transduction GO:0009967 223 0.151
Human
axon choice point recognition GO:0016198 26 0.148
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.147
carboxylic acid metabolic process GO:0019752 92 0.138
positive regulation of response to stimulus GO:0048584 323 0.137
Human
cell cell adhesion GO:0098609 26 0.136
localization of cell GO:0051674 257 0.131
Human Zebrafish Mouse Worm
photoreceptor cell axon guidance GO:0072499 23 0.122
regulation of anatomical structure morphogenesis GO:0022603 242 0.122
Human Zebrafish Mouse Rat Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.119
Human Mouse
positive regulation of protein metabolic process GO:0051247 128 0.119
Human Mouse
morphogenesis of a branching structure GO:0001763 45 0.118
Zebrafish Mouse
establishment of localization in cell GO:0051649 402 0.117
regulation of cellular component size GO:0032535 98 0.115
Human Zebrafish Mouse Rat Fly
dendrite development GO:0016358 204 0.114
regulation of protein metabolic process GO:0051246 256 0.106
Human Mouse
regulation of cellular protein metabolic process GO:0032268 243 0.106
Human Mouse
synaptic target recognition GO:0008039 45 0.105
establishment or maintenance of cell polarity GO:0007163 167 0.100
negative regulation of protein metabolic process GO:0051248 85 0.099
Mouse
oocyte development GO:0048599 124 0.097
eye photoreceptor cell development GO:0042462 81 0.091
imaginal disc derived wing morphogenesis GO:0007476 337 0.089
compound eye morphogenesis GO:0001745 249 0.089
compound eye photoreceptor cell differentiation GO:0001751 140 0.087
locomotory behavior GO:0007626 176 0.086
regulation of intracellular signal transduction GO:1902531 236 0.085
Human Mouse
positive regulation of cell development GO:0010720 61 0.083
Human Mouse
forebrain development GO:0030900 2 0.081
Human Mouse
organonitrogen compound metabolic process GO:1901564 318 0.081
Human Mouse
regulation of cell death GO:0010941 173 0.079
appendage morphogenesis GO:0035107 397 0.079
positive regulation of hydrolase activity GO:0051345 78 0.078
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.078
positive regulation of signaling GO:0023056 243 0.078
Human
regulation of cell growth GO:0001558 43 0.077
Human Zebrafish Mouse Rat
macromolecular complex assembly GO:0065003 256 0.077
growth GO:0040007 359 0.076
Human Zebrafish Mouse Rat
negative regulation of cellular component organization GO:0051129 108 0.074
Mouse Rat
camera type eye development GO:0043010 4 0.073
negative regulation of gene expression GO:0010629 387 0.073
Human Mouse
immune response activating signal transduction GO:0002757 2 0.073
positive regulation of neurogenesis GO:0050769 41 0.070
Human Mouse
compound eye development GO:0048749 307 0.070
positive regulation of developmental growth GO:0048639 62 0.069
Human
meiotic nuclear division GO:0007126 151 0.068
notch signaling pathway GO:0007219 120 0.067
actin cytoskeleton organization GO:0030036 206 0.066
Worm
regulation of synapse organization GO:0050807 110 0.066
negative regulation of cellular metabolic process GO:0031324 382 0.062
Human Mouse
mrna metabolic process GO:0016071 124 0.061
negative regulation of cellular protein metabolic process GO:0032269 85 0.061
Mouse
synapse organization GO:0050808 196 0.060
Fly
embryo development ending in birth or egg hatching GO:0009792 152 0.059
Zebrafish Mouse Fly
digestive system development GO:0055123 149 0.058
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.058
Human Mouse
dorsal ventral axon guidance GO:0033563 2 0.057
single organismal cell cell adhesion GO:0016337 45 0.056
Human
imaginal disc derived appendage development GO:0048737 399 0.055
phosphorylation GO:0016310 294 0.055
Human Mouse
regulation of cellular component biogenesis GO:0044087 201 0.054
actin filament based process GO:0030029 220 0.054
Worm
hematopoietic or lymphoid organ development GO:0048534 57 0.054
Zebrafish Mouse
brain development GO:0007420 120 0.054
Human Zebrafish Mouse Fly
negative regulation of response to stimulus GO:0048585 258 0.053
Mouse
heterocycle catabolic process GO:0046700 166 0.052
Human Mouse
positive regulation of nervous system development GO:0051962 69 0.050
Human Mouse
immune system process GO:0002376 347 0.050
Zebrafish Mouse
body morphogenesis GO:0010171 2 0.050
Worm
regulation of synapse assembly GO:0051963 94 0.049
biological adhesion GO:0022610 138 0.049
Human Worm
organic substance transport GO:0071702 257 0.049
positive regulation of proteolysis GO:0045862 52 0.049
single organism carbohydrate metabolic process GO:0044723 72 0.049
epithelial cell differentiation GO:0030855 322 0.048
catabolic process GO:0009056 409 0.047
Human Mouse
negative regulation of developmental growth GO:0048640 64 0.047
Mouse Rat
response to organic substance GO:0010033 284 0.047
negative regulation of immune system process GO:0002683 50 0.046
mitotic spindle organization GO:0007052 220 0.046
apoptotic process GO:0006915 159 0.046
Rat
morphogenesis of an epithelium GO:0002009 276 0.046
Zebrafish Mouse Worm
mushroom body development GO:0016319 70 0.046
protein modification by small protein conjugation GO:0032446 79 0.045
compound eye photoreceptor development GO:0042051 78 0.044
nucleobase containing compound catabolic process GO:0034655 165 0.043
Human Mouse
retina morphogenesis in camera type eye GO:0060042 2 0.043
protein localization GO:0008104 284 0.042
positive regulation of catalytic activity GO:0043085 118 0.041
Human Mouse
organophosphate metabolic process GO:0019637 195 0.040
Human Mouse
small molecule metabolic process GO:0044281 305 0.040
Human Mouse
chromatin assembly or disassembly GO:0006333 52 0.040
positive regulation of intracellular signal transduction GO:1902533 116 0.039
Human
regulation of multicellular organismal development GO:2000026 414 0.039
Human Zebrafish Mouse Rat Fly
vesicle mediated transport GO:0016192 381 0.039
purine ribonucleotide metabolic process GO:0009150 145 0.037
Human Mouse
regulation of cell proliferation GO:0042127 163 0.037
regulation of notch signaling pathway GO:0008593 100 0.037
regulation of cellular component movement GO:0051270 42 0.036
Human Mouse Worm Fly
cell proliferation GO:0008283 299 0.036
Zebrafish
photoreceptor cell development GO:0042461 96 0.036
negative regulation of cell differentiation GO:0045596 143 0.035
Mouse Rat
muscle structure development GO:0061061 224 0.035
Human Mouse
immune response regulating signaling pathway GO:0002764 2 0.035
embryonic morphogenesis GO:0048598 206 0.035
Zebrafish Mouse Worm
immune system development GO:0002520 57 0.034
Zebrafish Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
Human Mouse
chromosome organization GO:0051276 360 0.034
cell migration GO:0016477 238 0.034
Human Zebrafish Mouse Worm
single organism biosynthetic process GO:0044711 206 0.033
regulation of response to dna damage stimulus GO:2001020 23 0.033
r7 cell differentiation GO:0045466 43 0.033
regulation of cell differentiation GO:0045595 302 0.033
Human Zebrafish Mouse Rat Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.033
Human Mouse
cellular macromolecular complex assembly GO:0034622 153 0.033
gastrulation GO:0007369 70 0.033
actin cytoskeleton reorganization GO:0031532 22 0.033
flight behavior GO:0007629 26 0.032
intracellular transport GO:0046907 228 0.031
positive regulation of cell migration GO:0030335 2 0.031
Human Mouse
negative regulation of signaling GO:0023057 219 0.030
multi organism behavior GO:0051705 175 0.029
germ cell migration GO:0008354 43 0.028
nuclear division GO:0000280 332 0.028
digestive tract development GO:0048565 149 0.028
positive regulation of cell communication GO:0010647 250 0.028
Human
nucleoside phosphate metabolic process GO:0006753 162 0.028
Human Mouse
positive regulation of cellular protein metabolic process GO:0032270 118 0.028
Human Mouse
cellular response to chemical stimulus GO:0070887 199 0.027
tube development GO:0035295 244 0.027
Zebrafish Mouse
response to radiation GO:0009314 155 0.027
neurological system process GO:0050877 358 0.026
Fly
adult behavior GO:0030534 137 0.026
ribonucleoside monophosphate metabolic process GO:0009161 51 0.026
photoreceptor cell differentiation GO:0046530 170 0.025
retina development in camera type eye GO:0060041 4 0.025
convergent extension GO:0060026 2 0.025
ribonucleoprotein complex disassembly GO:0032988 1 0.025
oocyte maturation GO:0001556 3 0.024
intracellular signal transduction GO:0035556 300 0.024
Human
axonal fasciculation GO:0007413 12 0.024
Zebrafish Mouse Worm
negative regulation of signal transduction GO:0009968 206 0.024
positive regulation of developmental process GO:0051094 143 0.024
Human Mouse
regulation of apoptotic process GO:0042981 130 0.023
positive regulation of apoptotic process GO:0043065 47 0.023
signal transduction by phosphorylation GO:0023014 107 0.023
Human
regulation of phosphatase activity GO:0010921 3 0.023
Human Mouse
single organism cell adhesion GO:0098602 47 0.023
Human
purine nucleoside triphosphate metabolic process GO:0009144 119 0.023
Human Mouse
response to other organism GO:0051707 293 0.022
establishment of organelle localization GO:0051656 122 0.022
spindle organization GO:0007051 253 0.022
cell maturation GO:0048469 144 0.022
mesoderm development GO:0007498 78 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
Human Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.021
amine metabolic process GO:0009308 12 0.021
regulation of cell shape GO:0008360 113 0.021
Human Mouse
germ line stem cell maintenance GO:0030718 50 0.021
organelle localization GO:0051640 148 0.021
dendrite morphogenesis GO:0048813 199 0.021
regulation of translation GO:0006417 56 0.021
dephosphorylation GO:0016311 51 0.021
Human Mouse
cellular response to nitrogen compound GO:1901699 51 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
regulation of locomotion GO:0040012 42 0.020
Human Mouse Worm Fly
negative regulation of phosphatase activity GO:0010923 3 0.020
Human Mouse
positive regulation of cellular component organization GO:0051130 156 0.020
Human Mouse
regulation of ras protein signal transduction GO:0046578 93 0.020
Human Mouse
ribonucleotide catabolic process GO:0009261 109 0.019
Human Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.019
Human Mouse
regulation of rho protein signal transduction GO:0035023 20 0.019
Human Mouse
regulation of cellular catabolic process GO:0031329 157 0.019
Human Mouse
regionalization GO:0003002 416 0.019
Mouse
regulation of hemocyte proliferation GO:0035206 37 0.019
response to oxygen containing compound GO:1901700 200 0.019
chromosome segregation GO:0007059 157 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
leg disc development GO:0035218 92 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
tube morphogenesis GO:0035239 191 0.018
Zebrafish Mouse
oviposition GO:0018991 19 0.018
regulation of cell development GO:0060284 215 0.018
Human Zebrafish Mouse Rat Fly
purine nucleoside catabolic process GO:0006152 112 0.018
Human Mouse
microtubule organizing center organization GO:0031023 168 0.018
negative regulation of transcription dna templated GO:0045892 237 0.017
Human Mouse
negative regulation of cell death GO:0060548 81 0.017
response to alcohol GO:0097305 95 0.017
organelle fission GO:0048285 340 0.017
spermatogenesis GO:0007283 200 0.017
negative regulation of nervous system development GO:0051961 92 0.016
Mouse Rat
regulation of hydrolase activity GO:0051336 97 0.016
Human Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
Human Mouse
cell cycle phase transition GO:0044770 140 0.016
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
Zebrafish Mouse
gland development GO:0048732 191 0.016
central nervous system neuron differentiation GO:0021953 8 0.016
Mouse
homeostatic process GO:0042592 199 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
response to organic cyclic compound GO:0014070 89 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
Human Mouse
regeneration GO:0031099 16 0.016
Zebrafish
positive regulation of rna biosynthetic process GO:1902680 266 0.015
protein phosphorylation GO:0006468 169 0.015
Human Mouse
regulation of cellular localization GO:0060341 136 0.015
neuron death GO:0070997 27 0.015
regulation of immune response GO:0050776 118 0.015
cellular ketone metabolic process GO:0042180 24 0.015
phagocytosis GO:0006909 215 0.015
chaeta development GO:0022416 97 0.015
aromatic compound catabolic process GO:0019439 166 0.015
Human Mouse
rho protein signal transduction GO:0007266 14 0.015
cellular protein modification process GO:0006464 438 0.015
Human Mouse
digestive tract morphogenesis GO:0048546 127 0.015
endomembrane system organization GO:0010256 119 0.015
ras protein signal transduction GO:0007265 88 0.014
intracellular protein transport GO:0006886 104 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
Human Mouse
organ growth GO:0035265 56 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
Human Mouse
cellular catabolic process GO:0044248 372 0.014
Human Mouse
regulation of cell cycle process GO:0010564 181 0.014
regulation of striated muscle contraction GO:0006942 2 0.013
protein dephosphorylation GO:0006470 27 0.013
positive regulation of molecular function GO:0044093 136 0.013
Human Mouse
regulation of response to stress GO:0080134 200 0.013
Human
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
Human Mouse
positive regulation of cell growth GO:0030307 19 0.013
Human
response to nitrogen compound GO:1901698 90 0.013
positive regulation of endopeptidase activity GO:0010950 26 0.013
meiotic cell cycle GO:0051321 171 0.013
ameboidal type cell migration GO:0001667 151 0.012
Zebrafish Mouse
regulation of peptidase activity GO:0052547 39 0.012
central nervous system neuron axonogenesis GO:0021955 7 0.012
positive regulation of gene expression GO:0010628 290 0.012
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.012
negative regulation of sequestering of calcium ion GO:0051283 2 0.012
regulation of protein serine threonine kinase activity GO:0071900 25 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
Human Mouse
response to hexose GO:0009746 3 0.012
axon target recognition GO:0007412 16 0.012
cell division GO:0051301 248 0.012
exocrine system development GO:0035272 162 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
Human Mouse
positive regulation of growth GO:0045927 75 0.012
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.012
Human Mouse
cellular response to nutrient GO:0031670 1 0.012
central nervous system projection neuron axonogenesis GO:0021952 6 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
protein transport GO:0015031 155 0.011
cellular response to hormone stimulus GO:0032870 44 0.011
proteolysis GO:0006508 192 0.011
positive regulation of protein complex assembly GO:0031334 22 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
Human Mouse
cellular response to peptide hormone stimulus GO:0071375 28 0.011
convergent extension involved in gastrulation GO:0060027 2 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.011
larval development GO:0002164 104 0.011
Zebrafish
nucleus localization GO:0051647 34 0.011
maintenance of location GO:0051235 73 0.011
kidney development GO:0001822 3 0.011
positive regulation of organelle organization GO:0010638 65 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
Human Mouse
tissue migration GO:0090130 155 0.010
Mouse
limb development GO:0060173 1 0.010
lipid metabolic process GO:0006629 121 0.010
regulation of cell motility GO:2000145 23 0.010
Human Mouse Worm

Sema-2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
syndrome DOID:225 0 0.015
Human
disease of anatomical entity DOID:7 0 0.012
Human
nervous system disease DOID:863 0 0.012
Human