Drosophila melanogaster

29 known processes

Pfrx (Dmel_CG3400)

6-phosphofructo-2-kinase

(Aliases: CG3400,Dmel\CG3400)

Pfrx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.548
adult behavior GO:0030534 137 0.343
response to oxygen containing compound GO:1901700 200 0.332
circadian rhythm GO:0007623 105 0.316
sleep GO:0030431 49 0.291
rhythmic process GO:0048511 106 0.250
response to nutrient levels GO:0031667 114 0.205
response to organic substance GO:0010033 284 0.173
regulation of circadian rhythm GO:0042752 49 0.164
wing disc morphogenesis GO:0007472 344 0.152
behavioral response to ethanol GO:0048149 49 0.150
response to ethanol GO:0045471 59 0.124
positive regulation of signaling GO:0023056 243 0.117
locomotory behavior GO:0007626 176 0.115
positive regulation of cellular biosynthetic process GO:0031328 316 0.103
positive regulation of signal transduction GO:0009967 223 0.101
transcription from rna polymerase ii promoter GO:0006366 368 0.090
positive regulation of response to stimulus GO:0048584 323 0.090
oxoacid metabolic process GO:0043436 103 0.088
response to organic cyclic compound GO:0014070 89 0.088
positive regulation of gene expression GO:0010628 290 0.082
positive regulation of biosynthetic process GO:0009891 316 0.081
positive regulation of transcription dna templated GO:0045893 266 0.081
ion transport GO:0006811 145 0.081
response to extracellular stimulus GO:0009991 116 0.079
response to alcohol GO:0097305 95 0.079
carboxylic acid metabolic process GO:0019752 92 0.078
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.077
response to endogenous stimulus GO:0009719 119 0.077
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.073
positive regulation of cell communication GO:0010647 250 0.073
growth GO:0040007 359 0.072
rhythmic behavior GO:0007622 76 0.068
epithelial cell differentiation GO:0030855 322 0.067
feeding behavior GO:0007631 50 0.066
post embryonic appendage morphogenesis GO:0035120 385 0.066
cell death GO:0008219 279 0.061
establishment of localization in cell GO:0051649 402 0.061
response to bacterium GO:0009617 198 0.060
organonitrogen compound metabolic process GO:1901564 318 0.058
negative regulation of nucleic acid templated transcription GO:1903507 240 0.057
response to nitrogen compound GO:1901698 90 0.056
circadian behavior GO:0048512 76 0.056
programmed cell death GO:0012501 257 0.055
positive regulation of multicellular organismal process GO:0051240 143 0.055
cellular response to chemical stimulus GO:0070887 199 0.053
regionalization GO:0003002 416 0.052
regulation of cellular ketone metabolic process GO:0010565 3 0.052
intracellular signal transduction GO:0035556 300 0.052
developmental growth GO:0048589 280 0.051
lipid biosynthetic process GO:0008610 46 0.048
regulation of cell differentiation GO:0045595 302 0.048
chemical homeostasis GO:0048878 92 0.047
regulation of cellular amine metabolic process GO:0033238 3 0.047
regulation of localization GO:0032879 275 0.046
vesicle mediated transport GO:0016192 381 0.046
positive regulation of macromolecule metabolic process GO:0010604 405 0.046
regulation of programmed cell death GO:0043067 152 0.045
endocytosis GO:0006897 310 0.045
monocarboxylic acid transport GO:0015718 3 0.042
negative regulation of gene expression GO:0010629 387 0.042
regulation of molecular function GO:0065009 217 0.042
regulation of transport GO:0051049 181 0.039
regulation of intracellular signal transduction GO:1902531 236 0.039
positive regulation of rna biosynthetic process GO:1902680 266 0.039
single organism biosynthetic process GO:0044711 206 0.038
neurological system process GO:0050877 358 0.038
regulation of anatomical structure size GO:0090066 163 0.038
dorsal ventral pattern formation GO:0009953 133 0.037
regulation of response to stress GO:0080134 200 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.035
protein modification process GO:0036211 438 0.035
response to hormone GO:0009725 45 0.035
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.035
negative regulation of rna metabolic process GO:0051253 251 0.035
negative regulation of rna biosynthetic process GO:1902679 240 0.034
response to abiotic stimulus GO:0009628 341 0.034
negative regulation of biosynthetic process GO:0009890 277 0.034
eye development GO:0001654 323 0.033
secretion GO:0046903 109 0.033
negative regulation of cellular biosynthetic process GO:0031327 277 0.033
organic substance transport GO:0071702 257 0.033
organic acid metabolic process GO:0006082 103 0.032
actin filament based process GO:0030029 220 0.032
ion homeostasis GO:0050801 55 0.032
positive regulation of immune system process GO:0002684 68 0.031
regulation of cellular response to stress GO:0080135 89 0.031
regulation of developmental growth GO:0048638 174 0.030
response to organophosphorus GO:0046683 2 0.030
cellular protein modification process GO:0006464 438 0.029
circadian sleep wake cycle process GO:0022410 24 0.029
actin filament organization GO:0007015 126 0.029
cellular response to nitrogen compound GO:1901699 51 0.029
small molecule biosynthetic process GO:0044283 37 0.029
cellular amino acid metabolic process GO:0006520 61 0.028
response to lipopolysaccharide GO:0032496 4 0.028
response to monosaccharide GO:0034284 4 0.027
phosphorylation GO:0016310 294 0.027
intracellular transport GO:0046907 228 0.027
positive regulation of cell motility GO:2000147 3 0.027
actin cytoskeleton organization GO:0030036 206 0.027
memory GO:0007613 94 0.026
imaginal disc pattern formation GO:0007447 91 0.026
cellular protein localization GO:0034613 160 0.026
regulation of protein metabolic process GO:0051246 256 0.025
positive regulation of intracellular signal transduction GO:1902533 116 0.025
cognition GO:0050890 141 0.025
g protein coupled receptor signaling pathway GO:0007186 136 0.025
single organism intracellular transport GO:1902582 207 0.024
negative regulation of transcription dna templated GO:0045892 237 0.024
regulation of cellular localization GO:0060341 136 0.024
biological adhesion GO:0022610 138 0.024
cellular divalent inorganic cation homeostasis GO:0072503 23 0.024
positive regulation of developmental process GO:0051094 143 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.024
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
cellular ketone metabolic process GO:0042180 24 0.023
small molecule metabolic process GO:0044281 305 0.023
actin polymerization or depolymerization GO:0008154 31 0.023
positive regulation of cell migration GO:0030335 2 0.023
carbohydrate homeostasis GO:0033500 12 0.022
amine metabolic process GO:0009308 12 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.022
death GO:0016265 284 0.022
aging GO:0007568 143 0.022
camera type eye morphogenesis GO:0048593 2 0.022
regulation of growth GO:0040008 233 0.022
cellular macromolecule localization GO:0070727 220 0.022
apoptotic process GO:0006915 159 0.022
regulation of apoptotic process GO:0042981 130 0.022
metal ion homeostasis GO:0055065 44 0.022
muscle organ development GO:0007517 127 0.021
maintenance of location GO:0051235 73 0.021
regulation of catalytic activity GO:0050790 185 0.021
cellular homeostasis GO:0019725 80 0.021
cellular ion homeostasis GO:0006873 39 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.021
regulation of immune system process GO:0002682 176 0.020
response to external biotic stimulus GO:0043207 293 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
circadian sleep wake cycle GO:0042745 28 0.020
organelle fission GO:0048285 340 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
xenobiotic catabolic process GO:0042178 1 0.020
phagocytosis GO:0006909 215 0.019
imaginal disc derived appendage development GO:0048737 399 0.019
cellular response to external stimulus GO:0071496 66 0.019
negative regulation of signal transduction GO:0009968 206 0.019
cellular lipid metabolic process GO:0044255 83 0.019
negative regulation of developmental process GO:0051093 201 0.019
response to other organism GO:0051707 293 0.019
vitamin metabolic process GO:0006766 2 0.019
learning or memory GO:0007611 141 0.018
cellular response to mechanical stimulus GO:0071260 2 0.018
embryonic morphogenesis GO:0048598 206 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
regulation of cell death GO:0010941 173 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
metal ion transport GO:0030001 74 0.018
positive regulation of behavior GO:0048520 19 0.018
macromolecule catabolic process GO:0009057 161 0.018
compound eye morphogenesis GO:0001745 249 0.018
appendage development GO:0048736 401 0.017
ion transmembrane transport GO:0034220 122 0.017
response to metal ion GO:0010038 23 0.017
localization of cell GO:0051674 257 0.017
mitotic cell cycle phase transition GO:0044772 138 0.017
cytoplasmic transport GO:0016482 130 0.017
cell division GO:0051301 248 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
regulation of behavior GO:0050795 75 0.017
organic hydroxy compound biosynthetic process GO:1901617 21 0.017
cellular response to oxygen containing compound GO:1901701 79 0.017
cellular amine metabolic process GO:0044106 12 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.016
defense response to other organism GO:0098542 225 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
endomembrane system organization GO:0010256 119 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
response to hexose GO:0009746 3 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
cellular response to hormone stimulus GO:0032870 44 0.016
cellular response to peptide hormone stimulus GO:0071375 28 0.015
anatomical structure homeostasis GO:0060249 97 0.015
retina development in camera type eye GO:0060041 4 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
regulation of steroid metabolic process GO:0019218 2 0.015
positive regulation of lipid metabolic process GO:0045834 4 0.015
response to organonitrogen compound GO:0010243 75 0.015
peptidyl amino acid modification GO:0018193 105 0.015
cellular catabolic process GO:0044248 372 0.015
protein complex assembly GO:0006461 200 0.015
response to insulin GO:0032868 29 0.015
cell motility GO:0048870 251 0.015
lipid metabolic process GO:0006629 121 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.015
regulation of phosphorylation GO:0042325 147 0.015
amide biosynthetic process GO:0043604 42 0.015
negative regulation of cell communication GO:0010648 223 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
signal release GO:0023061 49 0.014
kidney development GO:0001822 3 0.014
axonogenesis GO:0007409 290 0.014
positive regulation of phosphorylation GO:0042327 87 0.014
response to biotic stimulus GO:0009607 294 0.014
regulation of neurogenesis GO:0050767 158 0.014
regulation of hormone levels GO:0010817 40 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
appendage morphogenesis GO:0035107 397 0.013
protein localization GO:0008104 284 0.013
adult locomotory behavior GO:0008344 76 0.013
oxidation reduction process GO:0055114 123 0.013
negative regulation of homeostatic process GO:0032845 2 0.013
synaptic transmission GO:0007268 288 0.013
cellular response to organic substance GO:0071310 132 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
cation transport GO:0006812 110 0.013
muscle structure development GO:0061061 224 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
regulation of ion transport GO:0043269 39 0.012
circadian sleep wake cycle sleep GO:0050802 23 0.012
macroautophagy GO:0016236 42 0.012
cellular chemical homeostasis GO:0055082 40 0.012
secretion by cell GO:0032940 101 0.012
sensory organ morphogenesis GO:0090596 260 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
fatty acid metabolic process GO:0006631 20 0.012
tissue morphogenesis GO:0048729 297 0.012
cellular metal ion homeostasis GO:0006875 31 0.012
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.012
epithelial cell development GO:0002064 274 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
organ growth GO:0035265 56 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
negative regulation of cell death GO:0060548 81 0.011
body morphogenesis GO:0010171 2 0.011
nuclear division GO:0000280 332 0.011
autophagy GO:0006914 108 0.011
protein phosphorylation GO:0006468 169 0.011
telencephalon development GO:0021537 2 0.011
response to glucose GO:0009749 2 0.011
neuron projection guidance GO:0097485 241 0.011
apoptotic signaling pathway GO:0097190 27 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
axon development GO:0061564 297 0.011
cellular amide metabolic process GO:0043603 80 0.011
camera type eye development GO:0043010 4 0.010
chemotaxis GO:0006935 249 0.010
organic substance catabolic process GO:1901575 308 0.010
compound eye development GO:0048749 307 0.010
epidermal cell differentiation GO:0009913 51 0.010
defense response to bacterium GO:0042742 178 0.010
regulation of multicellular organismal development GO:2000026 414 0.010
response to calcium ion GO:0051592 1 0.010
peptide metabolic process GO:0006518 80 0.010
proteolysis GO:0006508 192 0.010
organelle assembly GO:0070925 198 0.010
regulation of catabolic process GO:0009894 170 0.010
skin development GO:0043588 65 0.010
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010

Pfrx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.091
cardiovascular system disease DOID:1287 0 0.031
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.015