Drosophila melanogaster

13 known processes

Poc1 (Dmel_CG10191)

Proteome of centrioles 1

(Aliases: Dmel\CG10191,CG10191,poc1)

Poc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
centrosome duplication GO:0051298 121 0.933
centriole replication GO:0007099 24 0.853
centrosome cycle GO:0007098 137 0.841
centriole centriole cohesion GO:0010457 5 0.805
centrosome organization GO:0051297 163 0.602
asymmetric neuroblast division GO:0055059 33 0.573
male meiosis GO:0007140 52 0.571
microtubule organizing center organization GO:0031023 168 0.541
organelle assembly GO:0070925 198 0.465
Human
centriole assembly GO:0098534 24 0.425
neuroblast division GO:0055057 35 0.420
asymmetric stem cell division GO:0098722 49 0.313
establishment of spindle orientation GO:0051294 18 0.272
microtubule anchoring GO:0034453 11 0.262
microtubule depolymerization GO:0007019 25 0.232
somatic stem cell division GO:0048103 37 0.228
regulation of microtubule based process GO:0032886 49 0.222
spindle assembly involved in mitosis GO:0090307 50 0.209
protein complex disassembly GO:0043241 36 0.208
regulation of microtubule depolymerization GO:0031114 24 0.201
regulation of cytoskeleton organization GO:0051493 89 0.198
establishment of organelle localization GO:0051656 122 0.193
negative regulation of cellular component organization GO:0051129 108 0.185
cell proliferation GO:0008283 299 0.183
Human
establishment of localization in cell GO:0051649 402 0.167
neural precursor cell proliferation GO:0061351 75 0.163
negative regulation of protein depolymerization GO:1901880 23 0.149
maintenance of location GO:0051235 73 0.143
stem cell division GO:0017145 69 0.140
centrosome separation GO:0051299 20 0.132
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.128
neuronal stem cell division GO:0036445 35 0.128
organelle localization GO:0051640 148 0.117
cellular component disassembly GO:0022411 46 0.116
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.114
regulation of protein complex disassembly GO:0043244 29 0.112
mitotic spindle organization GO:0007052 220 0.110
mitotic cytokinesis GO:0000281 50 0.107
protein complex biogenesis GO:0070271 201 0.105
metaphase plate congression GO:0051310 19 0.104
negative regulation of microtubule depolymerization GO:0007026 21 0.096
cellular protein localization GO:0034613 160 0.096
cytoskeleton dependent cytokinesis GO:0061640 81 0.095
protein depolymerization GO:0051261 31 0.094
establishment or maintenance of cell polarity GO:0007163 167 0.094
chromosome localization GO:0050000 20 0.090
cellular protein complex disassembly GO:0043624 35 0.089
spindle organization GO:0007051 253 0.089
negative regulation of cytoskeleton organization GO:0051494 30 0.088
maintenance of protein location GO:0045185 28 0.083
stem cell proliferation GO:0072089 88 0.081
maintenance of protein location in cell GO:0032507 26 0.080
protein localization GO:0008104 284 0.079
sister chromatid segregation GO:0000819 92 0.077
mitotic spindle midzone assembly GO:0051256 1 0.077
regulation of microtubule cytoskeleton organization GO:0070507 41 0.075
meiosis i GO:0007127 59 0.075
regulation of cell differentiation GO:0045595 302 0.075
spindle assembly GO:0051225 80 0.074
regulation of protein depolymerization GO:1901879 27 0.074
negative regulation of protein complex disassembly GO:0043242 23 0.073
regulation of spindle organization GO:0090224 17 0.071
maintenance of location in cell GO:0051651 28 0.071
microtubule bundle formation GO:0001578 27 0.070
macromolecular complex disassembly GO:0032984 37 0.068
mitotic spindle elongation GO:0000022 81 0.064
neuroblast proliferation GO:0007405 74 0.062
cellular macromolecule localization GO:0070727 220 0.056
spindle localization GO:0051653 22 0.055
regulation of neurogenesis GO:0050767 158 0.050
mitotic metaphase plate congression GO:0007080 13 0.050
catabolic process GO:0009056 409 0.049
positive regulation of transcription dna templated GO:0045893 266 0.049
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.048
cellular catabolic process GO:0044248 372 0.047
cell division GO:0051301 248 0.046
chromosome organization GO:0051276 360 0.044
appendage development GO:0048736 401 0.044
regulation of cell development GO:0060284 215 0.044
establishment of chromosome localization GO:0051303 20 0.043
regulation of molecular function GO:0065009 217 0.040
peptidyl amino acid modification GO:0018193 105 0.040
protein modification process GO:0036211 438 0.039
transcription from rna polymerase ii promoter GO:0006366 368 0.039
regulation of nervous system development GO:0051960 248 0.038
mitotic spindle stabilization GO:0043148 6 0.038
regulation of multicellular organismal development GO:2000026 414 0.037
mitotic centrosome separation GO:0007100 8 0.036
macromolecular complex assembly GO:0065003 256 0.035
spindle stabilization GO:0043146 14 0.035
positive regulation of cellular component biogenesis GO:0044089 80 0.035
positive regulation of biosynthetic process GO:0009891 316 0.034
microtubule polymerization or depolymerization GO:0031109 39 0.034
organic substance catabolic process GO:1901575 308 0.034
mitotic nuclear division GO:0007067 213 0.033
cellular protein modification process GO:0006464 438 0.033
organic substance transport GO:0071702 257 0.033
cytokinetic cell separation GO:0000920 1 0.032
carboxylic acid metabolic process GO:0019752 92 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.032
response to radiation GO:0009314 155 0.032
single organism intracellular transport GO:1902582 207 0.031
negative regulation of gene expression epigenetic GO:0045814 77 0.031
proteolysis GO:0006508 192 0.031
meiotic nuclear division GO:0007126 151 0.030
negative regulation of transcription dna templated GO:0045892 237 0.030
lateral inhibition GO:0046331 206 0.029
cytokinetic process GO:0032506 27 0.027
regulation of actin cytoskeleton organization GO:0032956 42 0.027
cellular amino acid metabolic process GO:0006520 61 0.027
spermatogenesis GO:0007283 200 0.027
heterocycle catabolic process GO:0046700 166 0.026
nucleus organization GO:0006997 45 0.026
positive regulation of protein metabolic process GO:0051247 128 0.026
small molecule metabolic process GO:0044281 305 0.026
protein dna complex assembly GO:0065004 63 0.025
post embryonic appendage morphogenesis GO:0035120 385 0.025
negative regulation of organelle organization GO:0010639 56 0.024
protein phosphorylation GO:0006468 169 0.024
single organism cellular localization GO:1902580 180 0.024
cellular response to uv GO:0034644 12 0.024
regulation of mitotic spindle organization GO:0060236 9 0.023
response to abiotic stimulus GO:0009628 341 0.023
phosphorylation GO:0016310 294 0.023
nuclear import GO:0051170 51 0.023
appendage morphogenesis GO:0035107 397 0.023
protein complex assembly GO:0006461 200 0.023
regulation of protein localization GO:0032880 76 0.023
regulation of programmed cell death GO:0043067 152 0.022
cytoplasmic transport GO:0016482 130 0.022
death GO:0016265 284 0.022
regulation of catabolic process GO:0009894 170 0.022
regulation of catalytic activity GO:0050790 185 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
positive regulation of catabolic process GO:0009896 105 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.021
eye morphogenesis GO:0048592 260 0.021
body morphogenesis GO:0010171 2 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
regulation of organelle organization GO:0033043 196 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
macromolecule catabolic process GO:0009057 161 0.020
regulation of cellular component biogenesis GO:0044087 201 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
positive regulation of molecular function GO:0044093 136 0.020
cell projection assembly GO:0030031 94 0.020
Human
microtubule based transport GO:0010970 42 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
protein catabolic process GO:0030163 101 0.020
positive regulation of cellular protein metabolic process GO:0032270 118 0.020
telomere organization GO:0032200 21 0.019
programmed cell death GO:0012501 257 0.019
negative regulation of signaling GO:0023057 219 0.019
nucleoside catabolic process GO:0009164 112 0.018
ubiquitin dependent protein catabolic process GO:0006511 78 0.018
attachment of spindle microtubules to kinetochore GO:0008608 5 0.018
cytokinesis GO:0000910 90 0.018
neuronal stem cell maintenance GO:0097150 4 0.018
nuclear division GO:0000280 332 0.018
eye development GO:0001654 323 0.018
rna localization GO:0006403 115 0.018
positive regulation of cellular catabolic process GO:0031331 95 0.018
mitotic sister chromatid segregation GO:0000070 87 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
meiotic sister chromatid cohesion GO:0051177 6 0.017
modification dependent protein catabolic process GO:0019941 78 0.017
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
spindle midzone assembly GO:0051255 4 0.017
immune system process GO:0002376 347 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.017
cell fate determination GO:0001709 91 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
leg disc morphogenesis GO:0007478 80 0.016
intracellular transport GO:0046907 228 0.016
response to light stimulus GO:0009416 124 0.016
organophosphate catabolic process GO:0046434 112 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
proteasomal protein catabolic process GO:0010498 59 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
compound eye development GO:0048749 307 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
alditol phosphate metabolic process GO:0052646 2 0.016
organophosphate metabolic process GO:0019637 195 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
positive regulation of gtpase activity GO:0043547 43 0.015
negative regulation of signal transduction GO:0009968 206 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
regulation of mitosis GO:0007088 56 0.015
cell death GO:0008219 279 0.015
organonitrogen compound metabolic process GO:1901564 318 0.015
mrna metabolic process GO:0016071 124 0.015
aromatic compound catabolic process GO:0019439 166 0.015
establishment of spindle localization GO:0051293 22 0.015
meiotic cell cycle process GO:1903046 132 0.015
positive regulation of signal transduction GO:0009967 223 0.014
guanosine containing compound catabolic process GO:1901069 74 0.014
regulation of cell proliferation GO:0042127 163 0.014
dna conformation change GO:0071103 105 0.014
regulation of cell death GO:0010941 173 0.014
establishment of cell polarity GO:0030010 40 0.014
regulation of synapse organization GO:0050807 110 0.014
negative regulation of gene expression GO:0010629 387 0.014
taxis GO:0042330 304 0.014
regulation of localization GO:0032879 275 0.014
wing disc morphogenesis GO:0007472 344 0.014
histone modification GO:0016570 106 0.014
cellular protein complex assembly GO:0043623 71 0.014
regulation of cellular catabolic process GO:0031329 157 0.013
cellular response to radiation GO:0071478 52 0.013
positive regulation of programmed cell death GO:0043068 62 0.013
actin filament organization GO:0007015 126 0.013
regulation of chromatin silencing GO:0031935 36 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.013
protein polymerization GO:0051258 42 0.013
cellular ketone metabolic process GO:0042180 24 0.013
regulation of apoptotic process GO:0042981 130 0.013
germline stem cell asymmetric division GO:0098728 15 0.013
forebrain development GO:0030900 2 0.013
response to bacterium GO:0009617 198 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
nucleoside metabolic process GO:0009116 127 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
cilium morphogenesis GO:0060271 39 0.013
Human Zebrafish
regulation of cellular localization GO:0060341 136 0.013
negative regulation of developmental process GO:0051093 201 0.013
gtp metabolic process GO:0046039 72 0.013
oxoacid metabolic process GO:0043436 103 0.013
apoptotic process GO:0006915 159 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
epithelial cell differentiation GO:0030855 322 0.012
male gamete generation GO:0048232 201 0.012
response to other organism GO:0051707 293 0.012
organic acid metabolic process GO:0006082 103 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
regulation of transferase activity GO:0051338 58 0.012
regionalization GO:0003002 416 0.012
neuromuscular junction development GO:0007528 149 0.011
organelle fission GO:0048285 340 0.011
response to uv GO:0009411 24 0.011
immune response GO:0006955 246 0.011
intracellular signal transduction GO:0035556 300 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
actin filament based process GO:0030029 220 0.011
pharynx development GO:0060465 1 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
meiotic chromosome segregation GO:0045132 59 0.011
negative regulation of neurogenesis GO:0050768 53 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
regulation of protein modification process GO:0031399 112 0.011
salivary gland development GO:0007431 162 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
regulation of actin filament based process GO:0032970 42 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
telencephalon development GO:0021537 2 0.011
negative regulation of cell communication GO:0010648 223 0.011
regulation of immune system process GO:0002682 176 0.010
regulation of wnt signaling pathway GO:0030111 68 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
regulation of synapse assembly GO:0051963 94 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
nicotinamide nucleotide metabolic process GO:0046496 2 0.010
rho protein signal transduction GO:0007266 14 0.010
negative regulation of response to stimulus GO:0048585 258 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
covalent chromatin modification GO:0016569 106 0.010
cellular protein catabolic process GO:0044257 83 0.010
neuron projection guidance GO:0097485 241 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
response to organic substance GO:0010033 284 0.010
negative regulation of epithelial cell proliferation GO:0050680 4 0.010
negative regulation of molecular function GO:0044092 51 0.010

Poc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
Human
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010