Drosophila melanogaster

103 known processes

EloA (Dmel_CG6755)

Elongin A

(Aliases: Elo-A,dEloA,Dmel\CG6755,CG6755)

EloA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage development GO:0048736 401 0.755
imaginal disc derived wing morphogenesis GO:0007476 337 0.688
post embryonic appendage morphogenesis GO:0035120 385 0.686
vesicle mediated transport GO:0016192 381 0.665
regionalization GO:0003002 416 0.642
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.470
positive regulation of macromolecule metabolic process GO:0010604 405 0.437
wnt signaling pathway GO:0016055 98 0.427
appendage morphogenesis GO:0035107 397 0.412
positive regulation of nucleic acid templated transcription GO:1903508 266 0.384
imaginal disc derived appendage morphogenesis GO:0035114 395 0.381
regulation of cell differentiation GO:0045595 302 0.298
imaginal disc derived appendage development GO:0048737 399 0.257
positive regulation of gene expression GO:0010628 290 0.253
cellular catabolic process GO:0044248 372 0.249
organic substance catabolic process GO:1901575 308 0.219
imaginal disc derived wing vein specification GO:0007474 48 0.200
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.182
single organism cellular localization GO:1902580 180 0.171
cell motility GO:0048870 251 0.163
positive regulation of cellular biosynthetic process GO:0031328 316 0.162
protein ubiquitination GO:0016567 70 0.155
catabolic process GO:0009056 409 0.152
positive regulation of rna metabolic process GO:0051254 271 0.144
chromatin organization GO:0006325 207 0.141
positive regulation of biosynthetic process GO:0009891 316 0.140
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.135
endocytosis GO:0006897 310 0.135
chondroitin sulfate metabolic process GO:0030204 2 0.134
cellular macromolecule catabolic process GO:0044265 136 0.133
endosomal transport GO:0016197 44 0.133
protein localization GO:0008104 284 0.133
positive regulation of transcription dna templated GO:0045893 266 0.116
protein catabolic process GO:0030163 101 0.113
inter male aggressive behavior GO:0002121 60 0.110
imaginal disc derived leg morphogenesis GO:0007480 80 0.109
embryonic morphogenesis GO:0048598 206 0.105
regulation of protein metabolic process GO:0051246 256 0.103
wing disc morphogenesis GO:0007472 344 0.102
tube development GO:0035295 244 0.102
positive regulation of rna biosynthetic process GO:1902680 266 0.096
negative regulation of cellular biosynthetic process GO:0031327 277 0.095
cell migration GO:0016477 238 0.091
macromolecule catabolic process GO:0009057 161 0.091
protein modification by small protein conjugation or removal GO:0070647 106 0.091
negative regulation of response to stimulus GO:0048585 258 0.091
spindle organization GO:0007051 253 0.089
establishment of localization in cell GO:0051649 402 0.085
aromatic compound catabolic process GO:0019439 166 0.085
memory GO:0007613 94 0.084
positive regulation of cell communication GO:0010647 250 0.084
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.083
localization of cell GO:0051674 257 0.080
digestive system development GO:0055123 149 0.079
positive regulation of signal transduction GO:0009967 223 0.079
proteolysis GO:0006508 192 0.077
tube morphogenesis GO:0035239 191 0.075
growth GO:0040007 359 0.074
regulation of localization GO:0032879 275 0.073
negative regulation of biosynthetic process GO:0009890 277 0.071
single organism intracellular transport GO:1902582 207 0.070
negative regulation of gene expression GO:0010629 387 0.070
nucleobase containing compound catabolic process GO:0034655 165 0.070
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.070
regulation of nervous system development GO:0051960 248 0.068
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.067
dna metabolic process GO:0006259 227 0.067
rna processing GO:0006396 147 0.066
cognition GO:0050890 141 0.065
negative regulation of cell differentiation GO:0045596 143 0.064
posttranscriptional regulation of gene expression GO:0010608 145 0.064
intracellular signal transduction GO:0035556 300 0.062
developmental growth GO:0048589 280 0.060
regulation of cellular protein metabolic process GO:0032268 243 0.060
histone modification GO:0016570 106 0.058
digestive tract morphogenesis GO:0048546 127 0.057
positive regulation of response to stimulus GO:0048584 323 0.056
cellular response to dna damage stimulus GO:0006974 223 0.056
eye development GO:0001654 323 0.055
heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process GO:0015014 5 0.055
negative regulation of multicellular organismal process GO:0051241 142 0.055
proteoglycan metabolic process GO:0006029 10 0.055
maintenance of location GO:0051235 73 0.055
heparin metabolic process GO:0030202 4 0.054
positive regulation of wnt signaling pathway GO:0030177 25 0.052
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 3 0.051
cellular macromolecule localization GO:0070727 220 0.051
regulation of phosphorus metabolic process GO:0051174 210 0.050
glycoprotein biosynthetic process GO:0009101 41 0.049
negative regulation of protein metabolic process GO:0051248 85 0.049
small molecule metabolic process GO:0044281 305 0.049
aminoglycan metabolic process GO:0006022 18 0.049
phagocytosis GO:0006909 215 0.049
regulation of multicellular organismal development GO:2000026 414 0.048
locomotory behavior GO:0007626 176 0.048
intracellular transport GO:0046907 228 0.048
notch receptor processing GO:0007220 13 0.047
negative regulation of nervous system development GO:0051961 92 0.046
regulation of notch signaling pathway GO:0008593 100 0.046
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.046
regulation of cellular component size GO:0032535 98 0.046
proteoglycan biosynthetic process GO:0030166 10 0.046
histone h4 k16 acetylation GO:0043984 4 0.045
protein modification process GO:0036211 438 0.045
centrosome organization GO:0051297 163 0.044
regulation of cell cycle GO:0051726 291 0.044
axon development GO:0061564 297 0.044
regulation of protein secretion GO:0050708 13 0.044
dna damage checkpoint GO:0000077 78 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.043
protein modification by small protein conjugation GO:0032446 79 0.042
cytoplasmic transport GO:0016482 130 0.042
smoothened signaling pathway GO:0007224 49 0.042
leg disc morphogenesis GO:0007478 80 0.042
single organism biosynthetic process GO:0044711 206 0.041
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.041
leg disc development GO:0035218 92 0.041
adult behavior GO:0030534 137 0.040
neurological system process GO:0050877 358 0.040
adult locomotory behavior GO:0008344 76 0.039
microtubule organizing center organization GO:0031023 168 0.039
mitotic cell cycle phase transition GO:0044772 138 0.039
regulation of behavior GO:0050795 75 0.038
chromosome organization GO:0051276 360 0.038
detection of stimulus GO:0051606 156 0.038
cellular protein localization GO:0034613 160 0.038
embryonic pattern specification GO:0009880 174 0.037
lateral inhibition GO:0046331 206 0.037
single organism behavior GO:0044708 391 0.037
regulation of neurogenesis GO:0050767 158 0.037
embryo development ending in birth or egg hatching GO:0009792 152 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.036
single organism carbohydrate metabolic process GO:0044723 72 0.036
regulation of smoothened signaling pathway GO:0008589 28 0.036
segmentation GO:0035282 207 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.035
regulation of catalytic activity GO:0050790 185 0.035
positive regulation of protein secretion GO:0050714 9 0.035
cell proliferation GO:0008283 299 0.035
cellular protein modification process GO:0006464 438 0.035
negative regulation of developmental process GO:0051093 201 0.034
heparan sulfate proteoglycan metabolic process GO:0030201 10 0.034
covalent chromatin modification GO:0016569 106 0.034
peptidyl threonine phosphorylation GO:0018107 2 0.034
mrna metabolic process GO:0016071 124 0.033
cell fate specification GO:0001708 71 0.033
cellular nitrogen compound catabolic process GO:0044270 165 0.033
enzyme linked receptor protein signaling pathway GO:0007167 179 0.032
notch signaling pathway GO:0007219 120 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.031
regulation of intracellular signal transduction GO:1902531 236 0.031
negative regulation of cell cycle process GO:0010948 109 0.031
chondroitin sulfate proteoglycan metabolic process GO:0050654 3 0.031
positive regulation of intracellular signal transduction GO:1902533 116 0.031
organic cyclic compound catabolic process GO:1901361 168 0.030
erbb signaling pathway GO:0038127 58 0.030
organonitrogen compound metabolic process GO:1901564 318 0.030
regulation of catabolic process GO:0009894 170 0.030
glycoprotein metabolic process GO:0009100 41 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
sensory organ morphogenesis GO:0090596 260 0.029
heterocycle catabolic process GO:0046700 166 0.029
protein complex biogenesis GO:0070271 201 0.029
regulation of mapk cascade GO:0043408 92 0.029
transcription from rna polymerase ii promoter GO:0006366 368 0.029
cell division GO:0051301 248 0.028
macromolecular complex assembly GO:0065003 256 0.028
regulation of cell cycle process GO:0010564 181 0.027
negative regulation of signal transduction GO:0009968 206 0.027
synaptic vesicle transport GO:0048489 50 0.027
membrane organization GO:0061024 112 0.027
taxis GO:0042330 304 0.027
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.027
gliogenesis GO:0042063 80 0.026
chemotaxis GO:0006935 249 0.026
regulation of wnt signaling pathway GO:0030111 68 0.026
dephosphorylation GO:0016311 51 0.026
cellular protein catabolic process GO:0044257 83 0.026
axon midline choice point recognition GO:0016199 26 0.026
positive regulation of molecular function GO:0044093 136 0.026
negative regulation of cell cycle GO:0045786 116 0.025
vesicle localization GO:0051648 55 0.025
regulation of translation GO:0006417 56 0.025
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.025
regulation of mitotic cell cycle GO:0007346 190 0.025
establishment or maintenance of cell polarity GO:0007163 167 0.024
response to abiotic stimulus GO:0009628 341 0.024
proteasomal protein catabolic process GO:0010498 59 0.024
protein polyubiquitination GO:0000209 11 0.024
nuclear division GO:0000280 332 0.024
learning or memory GO:0007611 141 0.024
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 5 0.023
phosphorylation GO:0016310 294 0.023
translation GO:0006412 69 0.023
establishment of protein localization GO:0045184 163 0.023
neuron projection guidance GO:0097485 241 0.023
gastrulation GO:0007369 70 0.023
compound eye development GO:0048749 307 0.023
regulation of developmental growth GO:0048638 174 0.023
meiotic chromosome segregation GO:0045132 59 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.022
determination of adult lifespan GO:0008340 137 0.022
positive regulation of signaling GO:0023056 243 0.022
glycosyl compound catabolic process GO:1901658 112 0.022
blastoderm segmentation GO:0007350 159 0.022
positive regulation of cell motility GO:2000147 3 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
purine nucleotide metabolic process GO:0006163 146 0.022
modification dependent protein catabolic process GO:0019941 78 0.022
ribonucleoside triphosphate metabolic process GO:0009199 119 0.021
regulation of cellular component movement GO:0051270 42 0.021
cellular ketone metabolic process GO:0042180 24 0.021
death GO:0016265 284 0.021
negative regulation of cell cycle phase transition GO:1901988 103 0.020
negative regulation of cellular protein metabolic process GO:0032269 85 0.020
mrna 3 end processing GO:0031124 28 0.020
chaeta development GO:0022416 97 0.020
tissue morphogenesis GO:0048729 297 0.020
digestive tract development GO:0048565 149 0.020
organic acid metabolic process GO:0006082 103 0.020
establishment of organelle localization GO:0051656 122 0.019
synaptic vesicle endocytosis GO:0048488 28 0.019
regulation of protein transport GO:0051223 57 0.019
regulation of synapse structure and activity GO:0050803 128 0.019
amine metabolic process GO:0009308 12 0.019
mitotic spindle organization GO:0007052 220 0.019
metal ion homeostasis GO:0055065 44 0.019
negative regulation of mitotic cell cycle GO:0045930 109 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
regulation of proteasomal protein catabolic process GO:0061136 39 0.019
regulation of cell migration GO:0030334 22 0.018
immune system process GO:0002376 347 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
cell cycle checkpoint GO:0000075 95 0.018
mitotic cell cycle checkpoint GO:0007093 88 0.018
multi organism behavior GO:0051705 175 0.018
cellular response to organic substance GO:0071310 132 0.018
metal ion transport GO:0030001 74 0.018
oxoacid metabolic process GO:0043436 103 0.018
synaptic transmission GO:0007268 288 0.018
mitochondrion distribution GO:0048311 10 0.018
axonogenesis GO:0007409 290 0.017
single organism cell adhesion GO:0098602 47 0.017
regulation of cytoplasmic transport GO:1903649 47 0.017
neuroblast division GO:0055057 35 0.017
detection of abiotic stimulus GO:0009582 66 0.017
positive regulation of protein transport GO:0051222 37 0.017
developmental pigmentation GO:0048066 68 0.017
intracellular protein transport GO:0006886 104 0.017
regulation of neuron differentiation GO:0045664 103 0.017
mrna processing GO:0006397 104 0.017
aggressive behavior GO:0002118 63 0.017
regulation of mitotic cell cycle phase transition GO:1901990 130 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
g2 dna damage checkpoint GO:0031572 69 0.017
mitotic g2 dna damage checkpoint GO:0007095 69 0.016
heparan sulfate proteoglycan biosynthetic process GO:0015012 10 0.016
cellularization GO:0007349 90 0.016
establishment of vesicle localization GO:0051650 51 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
aminoglycan biosynthetic process GO:0006023 11 0.016
poly a mrna export from nucleus GO:0016973 5 0.016
ubiquitin dependent protein catabolic process GO:0006511 78 0.016
response to radiation GO:0009314 155 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
asymmetric neuroblast division GO:0055059 33 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.016
stem cell development GO:0048864 79 0.016
fibroblast growth factor receptor signaling pathway GO:0008543 10 0.016
germ line stem cell maintenance GO:0030718 50 0.016
regulation of locomotion GO:0040012 42 0.015
single organism catabolic process GO:0044712 228 0.015
negative regulation of neurogenesis GO:0050768 53 0.015
divalent inorganic cation homeostasis GO:0072507 29 0.015
regulation of anatomical structure size GO:0090066 163 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.015
eye morphogenesis GO:0048592 260 0.015
regulation of vesicle mediated transport GO:0060627 59 0.015
regulation of molecular function GO:0065009 217 0.015
mating behavior GO:0007617 106 0.015
periodic partitioning GO:0007365 29 0.015
cellular polysaccharide biosynthetic process GO:0033692 7 0.015
chromatin modification GO:0016568 147 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
secondary metabolic process GO:0019748 75 0.014
glycosaminoglycan metabolic process GO:0030203 11 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
organelle localization GO:0051640 148 0.014
regulation of protein localization GO:0032880 76 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
mitochondrion localization GO:0051646 17 0.014
cell cycle phase transition GO:0044770 140 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
regulation of cell motility GO:2000145 23 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
mapk cascade GO:0000165 107 0.013
epithelial cell development GO:0002064 274 0.013
regulation of cell development GO:0060284 215 0.013
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.013
establishment of cell polarity GO:0030010 40 0.013
rna 3 end processing GO:0031123 45 0.013
regulation of mrna splicing via spliceosome GO:0048024 64 0.013
embryonic hindgut morphogenesis GO:0048619 48 0.013
regulation of cell size GO:0008361 63 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
nephron development GO:0072006 3 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
regulation of endocytosis GO:0030100 37 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
endomembrane system organization GO:0010256 119 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
regulation of nuclear division GO:0051783 58 0.012
regulation of response to external stimulus GO:0032101 115 0.012
multi multicellular organism process GO:0044706 123 0.012
regulation of transport GO:0051049 181 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
carbohydrate metabolic process GO:0005975 82 0.012
organelle fission GO:0048285 340 0.012
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.012
long term memory GO:0007616 62 0.012
blood circulation GO:0008015 26 0.011
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
anatomical structure homeostasis GO:0060249 97 0.011
single organism membrane organization GO:0044802 93 0.011
dna repair GO:0006281 54 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
mating GO:0007618 120 0.011
divalent metal ion transport GO:0070838 26 0.011
wound healing GO:0042060 75 0.011
dna integrity checkpoint GO:0031570 81 0.011
decapentaplegic signaling pathway GO:0008101 19 0.011
stem cell differentiation GO:0048863 117 0.011
intracellular distribution of mitochondria GO:0048312 5 0.011
cellular response to abiotic stimulus GO:0071214 58 0.011
central nervous system development GO:0007417 201 0.011
negative regulation of erbb signaling pathway GO:1901185 29 0.011
endodermal cell differentiation GO:0035987 3 0.011
quinone metabolic process GO:1901661 1 0.011
sensory neuron axon guidance GO:0097374 2 0.010
negative regulation of signaling GO:0023057 219 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
positive regulation of catabolic process GO:0009896 105 0.010
camera type eye development GO:0043010 4 0.010
positive regulation of mapk cascade GO:0043410 63 0.010
somatic stem cell division GO:0048103 37 0.010
ommochrome metabolic process GO:0046152 19 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
negative regulation of phosphorus metabolic process GO:0010563 45 0.010

EloA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
disease of cellular proliferation DOID:14566 0 0.027
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.018
musculoskeletal system cancer DOID:0060100 0 0.010
connective tissue cancer DOID:201 0 0.010