Drosophila melanogaster

30 known processes

Men (Dmel_CG10120)

Malic enzyme

(Aliases: ME,Me,MDH,anon-WO0118547.278,mem,men,Mdh-NADP,Dmel\CG10120,CG10120)

Men biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
acetaldehyde metabolic process GO:0006117 5 0.646
single organism behavior GO:0044708 391 0.574
nad metabolic process GO:0019674 1 0.559
response to ethanol GO:0045471 59 0.438
pyruvate metabolic process GO:0006090 7 0.303
organonitrogen compound metabolic process GO:1901564 318 0.282
nicotinamide nucleotide metabolic process GO:0046496 2 0.224
peptide metabolic process GO:0006518 80 0.196
response to oxygen containing compound GO:1901700 200 0.182
hormone catabolic process GO:0042447 3 0.155
vesicle mediated transport GO:0016192 381 0.131
organonitrogen compound biosynthetic process GO:1901566 117 0.116
response to alcohol GO:0097305 95 0.101
behavioral response to ethanol GO:0048149 49 0.095
single organism biosynthetic process GO:0044711 206 0.092
cell redox homeostasis GO:0045454 5 0.085
acyl coa metabolic process GO:0006637 3 0.064
cellular lipid metabolic process GO:0044255 83 0.064
catabolic process GO:0009056 409 0.062
adult behavior GO:0030534 137 0.061
nucleoside phosphate metabolic process GO:0006753 162 0.061
ion transport GO:0006811 145 0.058
multicellular organismal aging GO:0010259 140 0.056
organophosphate metabolic process GO:0019637 195 0.055
oxidation reduction process GO:0055114 123 0.054
response to heat GO:0009408 63 0.054
negative regulation of cellular metabolic process GO:0031324 382 0.053
pyridine containing compound metabolic process GO:0072524 3 0.052
mrna metabolic process GO:0016071 124 0.050
endocytosis GO:0006897 310 0.048
negative regulation of biosynthetic process GO:0009890 277 0.047
dna metabolic process GO:0006259 227 0.047
aging GO:0007568 143 0.046
oxidoreduction coenzyme metabolic process GO:0006733 2 0.046
determination of adult lifespan GO:0008340 137 0.046
sulfur compound metabolic process GO:0006790 59 0.044
response to organic substance GO:0010033 284 0.043
single organism carbohydrate metabolic process GO:0044723 72 0.042
ribonucleoside biosynthetic process GO:0042455 3 0.042
anion transmembrane transport GO:0098656 26 0.036
small molecule metabolic process GO:0044281 305 0.035
memory GO:0007613 94 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
organic substance catabolic process GO:1901575 308 0.034
phagocytosis GO:0006909 215 0.033
single organism catabolic process GO:0044712 228 0.032
oxoacid metabolic process GO:0043436 103 0.032
pyridine nucleotide metabolic process GO:0019362 2 0.032
juvenile hormone metabolic process GO:0006716 3 0.031
succinate transmembrane transport GO:0071422 2 0.030
regulation of protein metabolic process GO:0051246 256 0.030
regulation of rna splicing GO:0043484 69 0.030
positive regulation of response to stimulus GO:0048584 323 0.029
sulfate transport GO:0008272 3 0.029
monocarboxylic acid metabolic process GO:0032787 29 0.028
cellular response to extracellular stimulus GO:0031668 64 0.028
appendage morphogenesis GO:0035107 397 0.028
positive regulation of cell communication GO:0010647 250 0.027
glutathione metabolic process GO:0006749 37 0.027
regulation of response to stress GO:0080134 200 0.026
nucleotide metabolic process GO:0009117 161 0.025
forebrain development GO:0030900 2 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
response to oxidative stress GO:0006979 86 0.024
organic acid metabolic process GO:0006082 103 0.024
thioester metabolic process GO:0035383 3 0.024
homeostatic process GO:0042592 199 0.024
striated muscle myosin thick filament assembly GO:0071688 3 0.024
organic substance transport GO:0071702 257 0.023
carbohydrate biosynthetic process GO:0016051 17 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
positive regulation of biosynthetic process GO:0009891 316 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
cellular response to oxygen containing compound GO:1901701 79 0.022
cellular catabolic process GO:0044248 372 0.022
carboxylic acid metabolic process GO:0019752 92 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
positive regulation of signaling GO:0023056 243 0.020
protein targeting to nucleus GO:0044744 51 0.019
post embryonic appendage morphogenesis GO:0035120 385 0.019
response to reactive oxygen species GO:0000302 24 0.019
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
organic acid transport GO:0015849 18 0.019
cell aging GO:0007569 2 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
cellular macromolecular complex assembly GO:0034622 153 0.018
glycerolipid metabolic process GO:0046486 34 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
cognition GO:0050890 141 0.018
cellular amide metabolic process GO:0043603 80 0.018
response to abiotic stimulus GO:0009628 341 0.017
spermatogenesis GO:0007283 200 0.017
glycosyl compound metabolic process GO:1901657 127 0.016
anion transport GO:0006820 41 0.016
lipid metabolic process GO:0006629 121 0.016
carbohydrate metabolic process GO:0005975 82 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
positive regulation of lipid metabolic process GO:0045834 4 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
regulation of hemocyte proliferation GO:0035206 37 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
response to extracellular stimulus GO:0009991 116 0.015
regulation of immune response GO:0050776 118 0.014
chemosensory behavior GO:0007635 106 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
protein maturation GO:0051604 71 0.014
metal ion transport GO:0030001 74 0.014
protein complex biogenesis GO:0070271 201 0.014
transmembrane transport GO:0055085 139 0.014
chromosome organization GO:0051276 360 0.014
nucleoside phosphate biosynthetic process GO:1901293 34 0.014
regulation of catabolic process GO:0009894 170 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
establishment of localization in cell GO:0051649 402 0.013
sleep GO:0030431 49 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
wound healing GO:0042060 75 0.013
cellular protein complex assembly GO:0043623 71 0.013
cellularization GO:0007349 90 0.013
mrna splicing via spliceosome GO:0000398 73 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
cellular response to insulin stimulus GO:0032869 28 0.013
epiboly involved in wound healing GO:0090505 2 0.012
wing disc morphogenesis GO:0007472 344 0.012
glucan biosynthetic process GO:0009250 2 0.012
acylglycerol metabolic process GO:0006639 12 0.012
cellular homeostasis GO:0019725 80 0.012
monocarboxylic acid transport GO:0015718 3 0.012
glucose metabolic process GO:0006006 5 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
succinate transport GO:0015744 2 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
mrna processing GO:0006397 104 0.012
telencephalon development GO:0021537 2 0.012
purine containing compound metabolic process GO:0072521 155 0.012
appendage development GO:0048736 401 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.011
larval development GO:0002164 104 0.011
mushroom body development GO:0016319 70 0.011
cation transport GO:0006812 110 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.011
cellular polysaccharide metabolic process GO:0044264 11 0.011
response to wounding GO:0009611 94 0.011
regulation of catalytic activity GO:0050790 185 0.011
positive regulation of cell death GO:0010942 69 0.011
negative regulation of cell cycle GO:0045786 116 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
positive regulation of catabolic process GO:0009896 105 0.011
cellular carbohydrate metabolic process GO:0044262 22 0.011
lateral inhibition GO:0046331 206 0.011
regulation of hydrolase activity GO:0051336 97 0.011
positive regulation of rna metabolic process GO:0051254 271 0.010
primary alcohol metabolic process GO:0034308 2 0.010
positive regulation of signal transduction GO:0009967 223 0.010
very long chain fatty acid metabolic process GO:0000038 4 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
protein processing GO:0016485 68 0.010
body morphogenesis GO:0010171 2 0.010
ion transmembrane transport GO:0034220 122 0.010

Men disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
hematopoietic system disease DOID:74 0 0.014
immune system disease DOID:2914 0 0.014
anemia DOID:2355 0 0.014
nervous system disease DOID:863 0 0.014
inherited metabolic disorder DOID:655 0 0.013
disease of metabolism DOID:0014667 0 0.013
neurodegenerative disease DOID:1289 0 0.011
central nervous system disease DOID:331 0 0.011