Drosophila melanogaster

195 known processes

14-3-3epsilon (Dmel_CG31196)

CG31196 gene product from transcript CG31196-RA

(Aliases: EK3-5,D14-3-3epsilon,Su(Raf)3B,14-3-3omicron,par-5,CG31196,14-3-3,14-3-3-e,143E_DROME,d14-3-3epsilon,l(3)j2B10,anon-WO0172774.141,Dmel\CG31196,CT24092,D14-3-3e,1433epsilon,SR3-9,14-3-3e,PAR-5,14-3-3 epsilon,anon-WO02059370.52,PAR5,14-3-30epsilon,Par-5)

14-3-3epsilon biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oocyte differentiation GO:0009994 145 0.997
mitotic nuclear division GO:0007067 213 0.993
negative regulation of cell cycle GO:0045786 116 0.985
regulation of mrna splicing via spliceosome GO:0048024 64 0.985
oocyte axis specification GO:0007309 108 0.984
oocyte development GO:0048599 124 0.980
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.980
male gamete generation GO:0048232 201 0.977
oocyte construction GO:0007308 112 0.969
mrna metabolic process GO:0016071 124 0.949
rna splicing via transesterification reactions GO:0000375 73 0.948
regulation of mrna processing GO:0050684 71 0.935
mrna splicing via spliceosome GO:0000398 73 0.933
fertilization GO:0009566 26 0.927
organelle fission GO:0048285 340 0.917
anterior posterior axis specification embryo GO:0008595 103 0.909
regulation of rna splicing GO:0043484 69 0.902
nuclear migration GO:0007097 20 0.900
regulation of mrna metabolic process GO:1903311 72 0.897
mrna processing GO:0006397 104 0.894
rna splicing GO:0008380 83 0.889
organelle assembly GO:0070925 198 0.875
anterior posterior axis specification GO:0009948 109 0.865
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.865
anterior posterior pattern specification GO:0009952 136 0.855
compound eye development GO:0048749 307 0.854
segmentation GO:0035282 207 0.851
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.849
spermatid development GO:0007286 98 0.849
pole plasm mrna localization GO:0019094 49 0.847
tripartite regional subdivision GO:0007351 103 0.829
pole plasm rna localization GO:0007316 52 0.823
actin cytoskeleton organization GO:0030036 206 0.818
compound eye morphogenesis GO:0001745 249 0.808
microtubule organizing center organization GO:0031023 168 0.799
nucleus localization GO:0051647 34 0.798
cellular protein modification process GO:0006464 438 0.784
Human Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.781
nuclear division GO:0000280 332 0.778
alternative mrna splicing via spliceosome GO:0000380 60 0.768
regulation of cell cycle GO:0051726 291 0.760
negative regulation of cell communication GO:0010648 223 0.748
oocyte microtubule cytoskeleton organization GO:0016325 35 0.748
cell maturation GO:0048469 144 0.734
regulation of developmental growth GO:0048638 174 0.688
mitotic spindle organization GO:0007052 220 0.685
actin filament organization GO:0007015 126 0.671
actin filament based process GO:0030029 220 0.669
embryonic pattern specification GO:0009880 174 0.669
chromosome segregation GO:0007059 157 0.661
Fly
cellular protein complex disassembly GO:0043624 35 0.640
spindle organization GO:0007051 253 0.626
regulation of pole plasm oskar mrna localization GO:0007317 27 0.620
regulation of mitotic cell cycle GO:0007346 190 0.619
protein complex disassembly GO:0043241 36 0.584
regulation of cellular protein metabolic process GO:0032268 243 0.564
Human Mouse
meiotic nuclear division GO:0007126 151 0.550
embryo development ending in birth or egg hatching GO:0009792 152 0.546
oocyte anterior posterior axis specification GO:0007314 72 0.540
cell cycle phase transition GO:0044770 140 0.503
regulation of cell differentiation GO:0045595 302 0.485
axis specification GO:0009798 167 0.477
translation GO:0006412 69 0.467
cell proliferation GO:0008283 299 0.464
pole plasm assembly GO:0007315 61 0.457
regulation of organelle organization GO:0033043 196 0.455
spermatogenesis GO:0007283 200 0.447
developmental growth GO:0048589 280 0.431
small gtpase mediated signal transduction GO:0007264 88 0.424
catabolic process GO:0009056 409 0.422
positive regulation of developmental process GO:0051094 143 0.413
meiotic cell cycle process GO:1903046 132 0.403
negative regulation of cellular metabolic process GO:0031324 382 0.398
Human Mouse
regulation of cellular catabolic process GO:0031329 157 0.397
determination of adult lifespan GO:0008340 137 0.395
cellular catabolic process GO:0044248 372 0.394
pronuclear migration GO:0035046 4 0.384
nucleobase containing compound catabolic process GO:0034655 165 0.384
negative regulation of transcription dna templated GO:0045892 237 0.380
response to temperature stimulus GO:0009266 106 0.378
Fly
cellular macromolecule catabolic process GO:0044265 136 0.373
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.371
spindle assembly GO:0051225 80 0.370
single fertilization GO:0007338 24 0.369
positive regulation of growth GO:0045927 75 0.367
head development GO:0060322 135 0.365
Human Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.353
regulation of transposition rna mediated GO:0010525 3 0.351
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.349
establishment of nucleus localization GO:0040023 26 0.341
organic cyclic compound catabolic process GO:1901361 168 0.340
axon development GO:0061564 297 0.339
positive regulation of cellular catabolic process GO:0031331 95 0.337
centrosome cycle GO:0007098 137 0.335
multicellular organism growth GO:0035264 46 0.333
tube morphogenesis GO:0035239 191 0.332
regulation of cell cycle process GO:0010564 181 0.331
negative regulation of developmental process GO:0051093 201 0.328
brain development GO:0007420 120 0.315
Human Mouse
eye development GO:0001654 323 0.308
positive regulation of developmental growth GO:0048639 62 0.306
transposition rna mediated GO:0032197 3 0.305
aromatic compound catabolic process GO:0019439 166 0.305
pole plasm oskar mrna localization GO:0045451 46 0.304
regulation of ras protein signal transduction GO:0046578 93 0.301
blastoderm segmentation GO:0007350 159 0.301
macromolecular complex assembly GO:0065003 256 0.283
rna localization GO:0006403 115 0.282
germ line cyst formation GO:0048134 44 0.281
germarium derived oocyte fate determination GO:0007294 26 0.275
nucleoside metabolic process GO:0009116 127 0.274
positive regulation of macromolecule metabolic process GO:0010604 405 0.270
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.268
organic substance catabolic process GO:1901575 308 0.265
positive regulation of multicellular organismal process GO:0051240 143 0.261
negative regulation of cellular biosynthetic process GO:0031327 277 0.255
germarium derived female germ line cyst formation GO:0030727 42 0.255
rna processing GO:0006396 147 0.255
regulation of protein metabolic process GO:0051246 256 0.253
Human Mouse
nuclear import GO:0051170 51 0.253
regulation of embryonic development GO:0045995 68 0.252
germ cell migration GO:0008354 43 0.252
intracellular transport GO:0046907 228 0.251
Mouse
positive regulation of protein metabolic process GO:0051247 128 0.244
stem cell differentiation GO:0048863 117 0.241
regulation of molecular function GO:0065009 217 0.236
Human
localization of cell GO:0051674 257 0.235
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.234
cellular component disassembly GO:0022411 46 0.230
regulation of catabolic process GO:0009894 170 0.229
developmental maturation GO:0021700 172 0.224
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.224
negative regulation of cell cycle process GO:0010948 109 0.223
proteasomal protein catabolic process GO:0010498 59 0.218
cytoplasm organization GO:0007028 64 0.217
cellular nitrogen compound catabolic process GO:0044270 165 0.212
eye morphogenesis GO:0048592 260 0.210
embryonic development via the syncytial blastoderm GO:0001700 148 0.208
regulation of multicellular organism growth GO:0040014 40 0.208
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.200
cystoblast division GO:0007282 10 0.199
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.198
actomyosin structure organization GO:0031032 56 0.197
regulation of cell cycle phase transition GO:1901987 130 0.195
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.195
negative regulation of cell cycle phase transition GO:1901988 103 0.194
maternal determination of anterior posterior axis embryo GO:0008358 74 0.193
meiotic cell cycle GO:0051321 171 0.182
centrosome organization GO:0051297 163 0.181
positive regulation of cell cycle GO:0045787 43 0.176
regulation of cellular component biogenesis GO:0044087 201 0.173
spermatid differentiation GO:0048515 114 0.172
protein targeting GO:0006605 64 0.170
Mouse
apoptotic process involved in development GO:1902742 20 0.169
negative regulation of rna metabolic process GO:0051253 251 0.167
regulation of translation GO:0006417 56 0.166
embryonic axis specification GO:0000578 107 0.166
protein import GO:0017038 55 0.163
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.163
growth GO:0040007 359 0.162
digestive system development GO:0055123 149 0.159
regulation of multicellular organismal development GO:2000026 414 0.159
open tracheal system development GO:0007424 204 0.156
macromolecular complex disassembly GO:0032984 37 0.156
rna catabolic process GO:0006401 37 0.155
mitotic cell cycle phase transition GO:0044772 138 0.155
female meiotic division GO:0007143 70 0.153
mitotic dna damage checkpoint GO:0044773 74 0.152
eggshell chorion assembly GO:0007306 66 0.149
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.149
axon guidance GO:0007411 233 0.143
female germ line stem cell asymmetric division GO:0048132 14 0.141
positive regulation of cell proliferation GO:0008284 47 0.136
proteolysis GO:0006508 192 0.136
cell division GO:0051301 248 0.136
macromolecule catabolic process GO:0009057 161 0.135
immune system process GO:0002376 347 0.132
embryonic morphogenesis GO:0048598 206 0.131
regulation of ras gtpase activity GO:0032318 38 0.131
cell cycle checkpoint GO:0000075 95 0.128
regulation of oocyte development GO:0060281 27 0.126
regionalization GO:0003002 416 0.125
protein phosphorylation GO:0006468 169 0.125
gland morphogenesis GO:0022612 145 0.123
cell death GO:0008219 279 0.119
negative regulation of cellular protein metabolic process GO:0032269 85 0.119
Human Mouse
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.110
dna metabolic process GO:0006259 227 0.110
regulation of embryonic pattern specification GO:1902875 27 0.108
centrosome duplication GO:0051298 121 0.108
oocyte dorsal ventral axis specification GO:0007310 34 0.106
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.105
nucleus organization GO:0006997 45 0.105
regulation of phosphate metabolic process GO:0019220 210 0.104
sister chromatid segregation GO:0000819 92 0.103
axonogenesis GO:0007409 290 0.101
ribonucleoprotein complex assembly GO:0022618 23 0.101
regulation of macroautophagy GO:0016241 15 0.100
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.097
response to biotic stimulus GO:0009607 294 0.097
nucleotide catabolic process GO:0009166 109 0.095
regulation of cell proliferation GO:0042127 163 0.095
establishment or maintenance of cell polarity GO:0007163 167 0.094
stem cell development GO:0048864 79 0.091
single organism behavior GO:0044708 391 0.090
Fly
regulation of catalytic activity GO:0050790 185 0.090
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.089
stem cell division GO:0017145 69 0.088
ribonucleoprotein complex subunit organization GO:0071826 28 0.087
negative regulation of rna biosynthetic process GO:1902679 240 0.084
sensory organ morphogenesis GO:0090596 260 0.082
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.082
purine nucleoside catabolic process GO:0006152 112 0.081
modification dependent protein catabolic process GO:0019941 78 0.080
muscle structure development GO:0061061 224 0.079
digestive tract development GO:0048565 149 0.079
positive regulation of rna metabolic process GO:0051254 271 0.079
posttranscriptional gene silencing GO:0016441 46 0.078
organic substance transport GO:0071702 257 0.077
Mouse
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.076
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.076
regulation of growth GO:0040008 233 0.076
positive regulation of nucleic acid templated transcription GO:1903508 266 0.076
negative regulation of cell differentiation GO:0045596 143 0.075
dna damage checkpoint GO:0000077 78 0.075
positive regulation of cell cycle process GO:0090068 28 0.074
female germ line stem cell maintenance GO:0036099 8 0.073
negative regulation of mitotic cell cycle GO:0045930 109 0.073
cell motility GO:0048870 251 0.072
striated muscle cell development GO:0055002 50 0.071
nucleoside phosphate metabolic process GO:0006753 162 0.070
posttranscriptional regulation of gene expression GO:0010608 145 0.070
Fly
regulation of programmed cell death GO:0043067 152 0.070
heterocycle catabolic process GO:0046700 166 0.069
germarium derived oocyte differentiation GO:0030706 29 0.068
aging GO:0007568 143 0.067
nucleoside phosphate catabolic process GO:1901292 110 0.066
regulation of transposition GO:0010528 13 0.065
nucleoside catabolic process GO:0009164 112 0.065
phosphorylation GO:0016310 294 0.064
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.064
purine containing compound metabolic process GO:0072521 155 0.064
cytokinesis GO:0000910 90 0.062
dna integrity checkpoint GO:0031570 81 0.061
chaeta morphogenesis GO:0008407 42 0.061
positive regulation of cellular protein metabolic process GO:0032270 118 0.061
terminal region determination GO:0007362 25 0.060
regulation of cell division GO:0051302 72 0.060
single organism cellular localization GO:1902580 180 0.059
synaptic growth at neuromuscular junction GO:0051124 119 0.058
ubiquitin dependent protein catabolic process GO:0006511 78 0.058
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.058
positive regulation of translation GO:0045727 12 0.057
ribonucleoside triphosphate catabolic process GO:0009203 108 0.057
regulation of proteasomal protein catabolic process GO:0061136 39 0.057
regulation of meiotic cell cycle GO:0051445 9 0.057
posttranscriptional gene silencing by rna GO:0035194 45 0.057
regulation of hydrolase activity GO:0051336 97 0.056
endomembrane system organization GO:0010256 119 0.056
positive regulation of gene expression GO:0010628 290 0.056
positive regulation of hydrolase activity GO:0051345 78 0.056
nucleoside triphosphate metabolic process GO:0009141 120 0.056
regulation of response to stress GO:0080134 200 0.055
positive regulation of cell development GO:0010720 61 0.055
developmental programmed cell death GO:0010623 138 0.055
germ line stem cell division GO:0042078 25 0.055
negative regulation of signal transduction GO:0009968 206 0.054
ras protein signal transduction GO:0007265 88 0.054
regulation of transferase activity GO:0051338 58 0.054
negative regulation of multicellular organismal process GO:0051241 142 0.053
negative regulation of transposition GO:0010529 12 0.053
hematopoietic or lymphoid organ development GO:0048534 57 0.052
nucleobase containing small molecule metabolic process GO:0055086 174 0.052
actin polymerization or depolymerization GO:0008154 31 0.052
nucleocytoplasmic transport GO:0006913 72 0.051
hemopoiesis GO:0030097 46 0.051
positive regulation of nervous system development GO:0051962 69 0.051
response to other organism GO:0051707 293 0.051
cytoplasmic microtubule organization GO:0031122 22 0.051
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.051
purine containing compound catabolic process GO:0072523 112 0.050
ribonucleotide catabolic process GO:0009261 109 0.050
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.049
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.049
positive regulation of signaling GO:0023056 243 0.049
mitotic sister chromatid segregation GO:0000070 87 0.049
enzyme linked receptor protein signaling pathway GO:0007167 179 0.048
dendrite development GO:0016358 204 0.047
mitotic cell cycle embryonic GO:0045448 38 0.047
Fly
cellular response to dna damage stimulus GO:0006974 223 0.047
modification dependent macromolecule catabolic process GO:0043632 79 0.046
negative regulation of organelle organization GO:0010639 56 0.046
response to radiation GO:0009314 155 0.046
negative regulation of biosynthetic process GO:0009890 277 0.046
exocrine system development GO:0035272 162 0.045
intracellular protein transport GO:0006886 104 0.045
Mouse
protein depolymerization GO:0051261 31 0.044
tube development GO:0035295 244 0.044
positive regulation of cellular component organization GO:0051130 156 0.044
establishment of localization in cell GO:0051649 402 0.044
Mouse
regulation of intracellular signal transduction GO:1902531 236 0.043
protein modification process GO:0036211 438 0.043
Human Mouse
synaptic transmission GO:0007268 288 0.042
body morphogenesis GO:0010171 2 0.042
germline stem cell asymmetric division GO:0098728 15 0.042
immune system development GO:0002520 57 0.042
regulation of purine nucleotide catabolic process GO:0033121 48 0.042
cellular component assembly involved in morphogenesis GO:0010927 151 0.042
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.041
digestive tract morphogenesis GO:0048546 127 0.041
response to uv GO:0009411 24 0.041
dna repair GO:0006281 54 0.041
gastrulation GO:0007369 70 0.041
fusome organization GO:0045478 13 0.041
purine nucleoside metabolic process GO:0042278 127 0.041
g2 dna damage checkpoint GO:0031572 69 0.040
compound eye retinal cell programmed cell death GO:0046667 23 0.040
positive regulation of protein modification process GO:0031401 58 0.040
male pronucleus assembly GO:0035039 6 0.040
cell cycle arrest GO:0007050 4 0.039
regulation of protein serine threonine kinase activity GO:0071900 25 0.039
cellular macromolecular complex assembly GO:0034622 153 0.039
negative regulation of meiotic cell cycle GO:0051447 2 0.039
segment polarity determination GO:0007367 25 0.038
positive regulation of multicellular organism growth GO:0040018 21 0.038
regulation of compound eye cone cell fate specification GO:0042682 4 0.038
ribonucleoside monophosphate metabolic process GO:0009161 51 0.037
cellular protein complex assembly GO:0043623 71 0.037
nucleotide metabolic process GO:0009117 161 0.037
asymmetric stem cell division GO:0098722 49 0.037
mitotic cell cycle checkpoint GO:0007093 88 0.036
regulation of mitotic cell cycle phase transition GO:1901990 130 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.036
regulation of phosphorus metabolic process GO:0051174 210 0.036
positive regulation of catabolic process GO:0009896 105 0.036
biological adhesion GO:0022610 138 0.035
dorsal ventral pattern formation GO:0009953 133 0.035
programmed cell death GO:0012501 257 0.035
meiotic cell cycle phase transition GO:0044771 4 0.035
oocyte fate determination GO:0030716 27 0.035
purine nucleoside triphosphate catabolic process GO:0009146 108 0.034
neuromuscular junction development GO:0007528 149 0.034
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.033
ovarian fusome organization GO:0030723 11 0.033
single organism nuclear import GO:1902593 51 0.033
negative regulation of signaling GO:0023057 219 0.032
purine nucleoside triphosphate metabolic process GO:0009144 119 0.032
dorsal ventral axis specification GO:0009950 66 0.032
positive regulation of neurogenesis GO:0050769 41 0.032
germarium derived egg chamber formation GO:0007293 101 0.031
negative regulation of protein metabolic process GO:0051248 85 0.031
Human Mouse
positive regulation of biosynthetic process GO:0009891 316 0.031
larval development GO:0002164 104 0.031
actin filament polymerization GO:0030041 27 0.030
muscle cell development GO:0055001 50 0.030
epithelial cell development GO:0002064 274 0.029
morphogenesis of a polarized epithelium GO:0001738 93 0.029
ribonucleoside triphosphate metabolic process GO:0009199 119 0.029
intrinsic apoptotic signaling pathway GO:0097193 16 0.028
regulation of response to external stimulus GO:0032101 115 0.028
cellular protein catabolic process GO:0044257 83 0.028
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.028
protein import into nucleus GO:0006606 51 0.028
epithelial cell differentiation GO:0030855 322 0.028
multicellular organismal aging GO:0010259 140 0.027
positive regulation of cell differentiation GO:0045597 64 0.027
regulation of proteolysis GO:0030162 87 0.027
glycosyl compound metabolic process GO:1901657 127 0.027
establishment of rna localization GO:0051236 47 0.027
response to light stimulus GO:0009416 124 0.027
cellular macromolecule localization GO:0070727 220 0.026
Mouse
protein catabolic process GO:0030163 101 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
nuclear export GO:0051168 24 0.026
respiratory system development GO:0060541 213 0.026
regulation of cytoskeleton organization GO:0051493 89 0.026
appendage morphogenesis GO:0035107 397 0.026
regulation of protein export from nucleus GO:0046825 3 0.026
asymmetric cell division GO:0008356 37 0.025
response to starvation GO:0042594 97 0.025
regulation of protein stability GO:0031647 43 0.025
Fly
regulation of gtp catabolic process GO:0033124 44 0.025
response to external biotic stimulus GO:0043207 293 0.025
cation transport GO:0006812 110 0.025
Human
mitotic g2 m transition checkpoint GO:0044818 70 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
cell growth GO:0016049 108 0.024
mitotic dna integrity checkpoint GO:0044774 75 0.024
rho protein signal transduction GO:0007266 14 0.024
single organism catabolic process GO:0044712 228 0.024
mrna catabolic process GO:0006402 33 0.024
positive regulation of intracellular protein transport GO:0090316 30 0.024
regulation of protein complex disassembly GO:0043244 29 0.023
ribonucleoside monophosphate catabolic process GO:0009158 39 0.023
eye photoreceptor cell development GO:0042462 81 0.023
lipid localization GO:0010876 54 0.023
organonitrogen compound catabolic process GO:1901565 128 0.023
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.022
regulation of actin filament length GO:0030832 27 0.022
regulation of protein phosphorylation GO:0001932 64 0.022
regulation of protein kinase activity GO:0045859 51 0.022
cytoskeleton dependent intracellular transport GO:0030705 44 0.022
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.022
autophagic vacuole assembly GO:0000045 2 0.022
positive regulation of nucleotide catabolic process GO:0030813 46 0.022
cell aging GO:0007569 2 0.022
dephosphorylation GO:0016311 51 0.022
Human Mouse
response to extracellular stimulus GO:0009991 116 0.021
positive regulation of mitotic cell cycle GO:0045931 34 0.021
response to abiotic stimulus GO:0009628 341 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.021
protein processing GO:0016485 68 0.021
microtubule based movement GO:0007018 51 0.021
protein polymerization GO:0051258 42 0.021
purine ribonucleotide catabolic process GO:0009154 109 0.021
establishment of spindle localization GO:0051293 22 0.020
response to endoplasmic reticulum stress GO:0034976 28 0.020
meiotic chromosome segregation GO:0045132 59 0.020
response to nutrient levels GO:0031667 114 0.020
regulation of epithelial cell proliferation GO:0050678 4 0.020
maintenance of location GO:0051235 73 0.020
glycosyl compound catabolic process GO:1901658 112 0.020
wing disc morphogenesis GO:0007472 344 0.019
regulation of synapse assembly GO:0051963 94 0.019
sarcomere organization GO:0045214 26 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
regulation of response to extracellular stimulus GO:0032104 18 0.019
g2 m transition of mitotic cell cycle GO:0000086 19 0.019
ribonucleoside metabolic process GO:0009119 127 0.019
signal transduction by phosphorylation GO:0023014 107 0.019
regulation of mitotic spindle organization GO:0060236 9 0.019
negative regulation of cellular component organization GO:0051129 108 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
ribose phosphate metabolic process GO:0019693 145 0.019
regulation of hemocyte proliferation GO:0035206 37 0.018
ribonucleoside catabolic process GO:0042454 112 0.018
cellular response to starvation GO:0009267 61 0.018
female germ line cyst formation GO:0048135 42 0.018
protein localization to nucleus GO:0034504 55 0.018
cellular response to nutrient levels GO:0031669 62 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.018
negative regulation of protein complex disassembly GO:0043242 23 0.017
regulation of epidermal cell differentiation GO:0045604 3 0.017
negative regulation of protein phosphorylation GO:0001933 17 0.017
negative regulation of synapse assembly GO:0051964 39 0.017
positive regulation of molecular function GO:0044093 136 0.017
actin cytoskeleton reorganization GO:0031532 22 0.017
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.017
protein modification by small protein conjugation or removal GO:0070647 106 0.017
pole cell formation GO:0007279 19 0.017
central nervous system morphogenesis GO:0021551 8 0.017
meiosis i GO:0007127 59 0.017
cellular response to organic substance GO:0071310 132 0.017
stress activated mapk cascade GO:0051403 52 0.017
cell cycle g2 m phase transition GO:0044839 22 0.017
gene silencing by rna GO:0031047 57 0.017
apical constriction involved in gastrulation GO:0003384 7 0.016
organophosphate catabolic process GO:0046434 112 0.016
regulation of intracellular transport GO:0032386 64 0.016
striated muscle myosin thick filament assembly GO:0071688 3 0.016
branching involved in open tracheal system development GO:0060446 45 0.016
gland development GO:0048732 191 0.016
photoreceptor cell development GO:0042461 96 0.016
meiotic g2 mi transition GO:0008315 3 0.015
eye antennal disc development GO:0035214 60 0.015
negative regulation of gene expression GO:0010629 387 0.015
atp metabolic process GO:0046034 49 0.015
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.015
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
establishment of tissue polarity GO:0007164 87 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
regulation of phosphorylation GO:0042325 147 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
response to virus GO:0009615 28 0.015
genitalia development GO:0048806 26 0.015
establishment of protein localization GO:0045184 163 0.015
Mouse
positive regulation of proteolysis GO:0045862 52 0.015
pole cell development GO:0007277 26 0.015
regulation of actin polymerization or depolymerization GO:0008064 27 0.014
mrna splice site selection GO:0006376 1 0.014
cell migration GO:0016477 238 0.014
death GO:0016265 284 0.014
glandular epithelial cell differentiation GO:0002067 1 0.014
negative regulation of apoptotic signaling pathway GO:2001234 5 0.014
meiotic spindle organization GO:0000212 36 0.014
regeneration GO:0031099 16 0.014
positive regulation of neurotransmitter secretion GO:0001956 2 0.014
single organism biosynthetic process GO:0044711 206 0.014
head involution GO:0008258 35 0.014

14-3-3epsilon disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
organ system cancer DOID:0050686 0 0.034
muscular disease DOID:0080000 0 0.028
disease of anatomical entity DOID:7 0 0.028
musculoskeletal system disease DOID:17 0 0.028
breast cancer DOID:1612 0 0.027
thoracic cancer DOID:5093 0 0.027
muscle tissue disease DOID:66 0 0.026