Drosophila melanogaster

15 known processes

MrgBP (Dmel_CG13746)

CG13746 gene product from transcript CG13746-RA

(Aliases: dMrgBP,dMrgB,CG13746,Dmel\CG13746)

MrgBP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization in cell GO:0051649 402 0.276
intracellular transport GO:0046907 228 0.269
cell death GO:0008219 279 0.112
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.086
positive regulation of macromolecule metabolic process GO:0010604 405 0.083
death GO:0016265 284 0.082
regulation of immune system process GO:0002682 176 0.079
immune system process GO:0002376 347 0.075
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.073
regulation of cell proliferation GO:0042127 163 0.066
programmed cell death GO:0012501 257 0.064
regulation of response to stress GO:0080134 200 0.064
endocytosis GO:0006897 310 0.059
negative regulation of biosynthetic process GO:0009890 277 0.057
positive regulation of cellular biosynthetic process GO:0031328 316 0.053
positive regulation of rna biosynthetic process GO:1902680 266 0.052
regionalization GO:0003002 416 0.051
vesicle mediated transport GO:0016192 381 0.049
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.049
positive regulation of biosynthetic process GO:0009891 316 0.048
cellular macromolecular complex assembly GO:0034622 153 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.043
cellular macromolecule localization GO:0070727 220 0.042
protein transport GO:0015031 155 0.042
protein localization GO:0008104 284 0.042
negative regulation of nucleic acid templated transcription GO:1903507 240 0.041
protein modification process GO:0036211 438 0.040
regulation of multicellular organismal development GO:2000026 414 0.040
cellular response to dna damage stimulus GO:0006974 223 0.040
establishment of protein localization GO:0045184 163 0.040
positive regulation of rna metabolic process GO:0051254 271 0.039
ribonucleoprotein complex subunit organization GO:0071826 28 0.039
organelle fission GO:0048285 340 0.037
positive regulation of transcription dna templated GO:0045893 266 0.036
cell cycle phase transition GO:0044770 140 0.036
single organism biosynthetic process GO:0044711 206 0.035
organic substance transport GO:0071702 257 0.035
protein dna complex subunit organization GO:0071824 86 0.034
organonitrogen compound metabolic process GO:1901564 318 0.032
cellular protein localization GO:0034613 160 0.032
intracellular protein transport GO:0006886 104 0.032
mitotic cell cycle phase transition GO:0044772 138 0.032
cytoplasmic transport GO:0016482 130 0.031
cell proliferation GO:0008283 299 0.030
mrna metabolic process GO:0016071 124 0.029
negative regulation of gene expression GO:0010629 387 0.028
secretion by cell GO:0032940 101 0.028
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.028
cellular protein modification process GO:0006464 438 0.027
immune response GO:0006955 246 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.027
single organism behavior GO:0044708 391 0.027
apoptotic process GO:0006915 159 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
regulation of cell cycle GO:0051726 291 0.026
mitotic dna damage checkpoint GO:0044773 74 0.026
rna processing GO:0006396 147 0.026
negative regulation of cell cycle process GO:0010948 109 0.025
regulation of cell death GO:0010941 173 0.025
eye development GO:0001654 323 0.025
dna damage checkpoint GO:0000077 78 0.024
cell division GO:0051301 248 0.024
defense response GO:0006952 300 0.024
homeostatic process GO:0042592 199 0.024
catabolic process GO:0009056 409 0.024
organic substance catabolic process GO:1901575 308 0.024
negative regulation of cell communication GO:0010648 223 0.024
organic acid metabolic process GO:0006082 103 0.023
phagocytosis GO:0006909 215 0.023
aromatic compound catabolic process GO:0019439 166 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
response to bacterium GO:0009617 198 0.023
chromosome organization GO:0051276 360 0.022
innate immune response GO:0045087 144 0.022
negative regulation of transcription dna templated GO:0045892 237 0.022
sensory organ morphogenesis GO:0090596 260 0.022
compound eye development GO:0048749 307 0.022
molting cycle chitin based cuticle GO:0007591 56 0.022
spindle organization GO:0007051 253 0.022
rna localization GO:0006403 115 0.022
oxoacid metabolic process GO:0043436 103 0.021
regulation of defense response GO:0031347 102 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
wing disc morphogenesis GO:0007472 344 0.021
negative regulation of immune system process GO:0002683 50 0.021
negative regulation of rna metabolic process GO:0051253 251 0.021
response to external biotic stimulus GO:0043207 293 0.021
regulation of catalytic activity GO:0050790 185 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.020
response to biotic stimulus GO:0009607 294 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
eye morphogenesis GO:0048592 260 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
positive regulation of catalytic activity GO:0043085 118 0.019
positive regulation of molecular function GO:0044093 136 0.019
negative regulation of cell cycle phase transition GO:1901988 103 0.019
negative regulation of multicellular organismal process GO:0051241 142 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
positive regulation of gene expression GO:0010628 290 0.018
chromatin organization GO:0006325 207 0.018
cellular catabolic process GO:0044248 372 0.018
adult behavior GO:0030534 137 0.018
macromolecule catabolic process GO:0009057 161 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.017
positive regulation of immune system process GO:0002684 68 0.017
regulation of cell cycle process GO:0010564 181 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
mitotic dna integrity checkpoint GO:0044774 75 0.017
regulation of cell differentiation GO:0045595 302 0.017
regulation of meiosis GO:0040020 3 0.017
regulation of hydrolase activity GO:0051336 97 0.017
chromatin modification GO:0016568 147 0.017
regulation of programmed cell death GO:0043067 152 0.016
molting cycle GO:0042303 56 0.016
single organism intracellular transport GO:1902582 207 0.016
mitotic g2 m transition checkpoint GO:0044818 70 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
embryonic pattern specification GO:0009880 174 0.016
defense response to bacterium GO:0042742 178 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
positive regulation of cell communication GO:0010647 250 0.015
appendage development GO:0048736 401 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
regulation of immune response GO:0050776 118 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
positive regulation of signaling GO:0023056 243 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
appendage morphogenesis GO:0035107 397 0.015
rna splicing GO:0008380 83 0.015
defense response to other organism GO:0098542 225 0.015
regulation of cell cycle phase transition GO:1901987 130 0.015
histone modification GO:0016570 106 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
regulation of molecular function GO:0065009 217 0.015
camera type eye development GO:0043010 4 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
regulation of protein modification process GO:0031399 112 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
nuclear division GO:0000280 332 0.014
retina development in camera type eye GO:0060041 4 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
smoothened signaling pathway GO:0007224 49 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
mitotic nuclear division GO:0007067 213 0.014
protein acylation GO:0043543 42 0.014
cell cycle checkpoint GO:0000075 95 0.014
covalent chromatin modification GO:0016569 106 0.013
g2 dna damage checkpoint GO:0031572 69 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
mrna splicing via spliceosome GO:0000398 73 0.013
cellular response to organic substance GO:0071310 132 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
regulation of innate immune response GO:0045088 71 0.013
small molecule metabolic process GO:0044281 305 0.013
cellular homeostasis GO:0019725 80 0.013
gland development GO:0048732 191 0.013
single organism catabolic process GO:0044712 228 0.013
secretion GO:0046903 109 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
dna integrity checkpoint GO:0031570 81 0.012
dna templated transcription initiation GO:0006352 25 0.012
heterocycle catabolic process GO:0046700 166 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
chemical homeostasis GO:0048878 92 0.012
eye antennal disc development GO:0035214 60 0.012
protein targeting GO:0006605 64 0.012
gene silencing GO:0016458 138 0.012
regulation of catabolic process GO:0009894 170 0.012
pole plasm rna localization GO:0007316 52 0.012
axis specification GO:0009798 167 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.011
mapk cascade GO:0000165 107 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
purine containing compound metabolic process GO:0072521 155 0.011
membrane organization GO:0061024 112 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
blastoderm segmentation GO:0007350 159 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
mitotic g2 dna damage checkpoint GO:0007095 69 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
regulation of localization GO:0032879 275 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
ras protein signal transduction GO:0007265 88 0.011
regulation of nuclear division GO:0051783 58 0.011
regulation of protein stability GO:0031647 43 0.011
neurological system process GO:0050877 358 0.010
ribonucleoprotein complex assembly GO:0022618 23 0.010
peptidyl amino acid modification GO:0018193 105 0.010
response to temperature stimulus GO:0009266 106 0.010
negative regulation of signal transduction GO:0009968 206 0.010
regulation of protein metabolic process GO:0051246 256 0.010
protein localization to organelle GO:0033365 82 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010

MrgBP disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029