Drosophila melanogaster

0 known processes

ppa (Dmel_CG9952)

partner of paired

(Aliases: I-55,Ppa,CG9952,Dmel\CG9952)

ppa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
wing disc morphogenesis GO:0007472 344 0.107
imaginal disc derived appendage development GO:0048737 399 0.075
regulation of catabolic process GO:0009894 170 0.070
appendage development GO:0048736 401 0.069
imaginal disc derived appendage morphogenesis GO:0035114 395 0.069
compound eye morphogenesis GO:0001745 249 0.066
imaginal disc derived wing morphogenesis GO:0007476 337 0.061
behavioral response to ethanol GO:0048149 49 0.054
synaptic transmission GO:0007268 288 0.049
protein modification process GO:0036211 438 0.049
actin filament based process GO:0030029 220 0.047
growth GO:0040007 359 0.047
regionalization GO:0003002 416 0.046
regulation of cellular catabolic process GO:0031329 157 0.044
post embryonic appendage morphogenesis GO:0035120 385 0.043
sensory organ morphogenesis GO:0090596 260 0.043
localization of cell GO:0051674 257 0.042
tissue morphogenesis GO:0048729 297 0.042
response to bacterium GO:0009617 198 0.041
proteolysis GO:0006508 192 0.041
regulation of phosphorus metabolic process GO:0051174 210 0.041
positive regulation of response to stimulus GO:0048584 323 0.040
neurological system process GO:0050877 358 0.040
eye morphogenesis GO:0048592 260 0.038
notch signaling pathway GO:0007219 120 0.037
developmental growth GO:0048589 280 0.037
appendage morphogenesis GO:0035107 397 0.037
forebrain development GO:0030900 2 0.036
adult behavior GO:0030534 137 0.036
regulation of multicellular organismal development GO:2000026 414 0.036
morphogenesis of an epithelium GO:0002009 276 0.036
actin cytoskeleton organization GO:0030036 206 0.036
cell motility GO:0048870 251 0.035
response to other organism GO:0051707 293 0.035
intracellular signal transduction GO:0035556 300 0.034
positive regulation of macromolecule metabolic process GO:0010604 405 0.034
cellular protein modification process GO:0006464 438 0.034
catabolic process GO:0009056 409 0.032
regulation of protein metabolic process GO:0051246 256 0.032
regulation of cell development GO:0060284 215 0.031
cellular response to dna damage stimulus GO:0006974 223 0.030
response to biotic stimulus GO:0009607 294 0.030
columnar cuboidal epithelial cell development GO:0002066 249 0.029
open tracheal system development GO:0007424 204 0.029
actin filament organization GO:0007015 126 0.029
positive regulation of cell communication GO:0010647 250 0.029
lateral inhibition GO:0046331 206 0.028
regulation of localization GO:0032879 275 0.028
vesicle mediated transport GO:0016192 381 0.028
cellular macromolecule catabolic process GO:0044265 136 0.028
negative regulation of developmental growth GO:0048640 64 0.028
regulation of nervous system development GO:0051960 248 0.028
regulation of mitotic cell cycle GO:0007346 190 0.027
phosphorylation GO:0016310 294 0.027
epithelial cell development GO:0002064 274 0.027
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.027
regulation of proteolysis GO:0030162 87 0.027
positive regulation of signaling GO:0023056 243 0.027
defense response GO:0006952 300 0.027
single organism behavior GO:0044708 391 0.026
cellular catabolic process GO:0044248 372 0.026
response to lipopolysaccharide GO:0032496 4 0.025
cell cell signaling involved in cell fate commitment GO:0045168 210 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
response to external biotic stimulus GO:0043207 293 0.025
response to abiotic stimulus GO:0009628 341 0.025
regulation of protein catabolic process GO:0042176 55 0.025
regulation of phosphate metabolic process GO:0019220 210 0.025
exocrine system development GO:0035272 162 0.025
regulation of cellular component biogenesis GO:0044087 201 0.025
positive regulation of cell motility GO:2000147 3 0.025
cell proliferation GO:0008283 299 0.025
protein modification by small protein conjugation or removal GO:0070647 106 0.024
telencephalon development GO:0021537 2 0.024
regulation of catalytic activity GO:0050790 185 0.024
negative regulation of growth GO:0045926 84 0.024
eye development GO:0001654 323 0.024
organelle fission GO:0048285 340 0.024
positive regulation of catabolic process GO:0009896 105 0.024
phagocytosis GO:0006909 215 0.024
negative regulation of signaling GO:0023057 219 0.023
epithelial cell differentiation GO:0030855 322 0.023
developmental programmed cell death GO:0010623 138 0.023
organic substance catabolic process GO:1901575 308 0.023
protein localization GO:0008104 284 0.023
transmembrane transport GO:0055085 139 0.023
positive regulation of proteolysis GO:0045862 52 0.023
negative regulation of gene expression GO:0010629 387 0.023
protein catabolic process GO:0030163 101 0.022
salivary gland development GO:0007431 162 0.022
respiratory system development GO:0060541 213 0.022
mitotic nuclear division GO:0007067 213 0.022
small molecule metabolic process GO:0044281 305 0.022
compound eye development GO:0048749 307 0.022
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
protein maturation GO:0051604 71 0.021
regulation of cell differentiation GO:0045595 302 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
salivary gland morphogenesis GO:0007435 145 0.021
compound eye photoreceptor cell differentiation GO:0001751 140 0.021
chromatin modification GO:0016568 147 0.021
eggshell formation GO:0030703 105 0.021
synapse organization GO:0050808 196 0.021
protein modification by small protein conjugation GO:0032446 79 0.021
protein ubiquitination GO:0016567 70 0.021
aromatic compound catabolic process GO:0019439 166 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
regulation of molecular function GO:0065009 217 0.021
cellular amide metabolic process GO:0043603 80 0.021
response to organic substance GO:0010033 284 0.021
positive regulation of hydrolase activity GO:0051345 78 0.020
positive regulation of cellular biosynthetic process GO:0031328 316 0.020
regulation of notch signaling pathway GO:0008593 100 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.020
programmed cell death GO:0012501 257 0.020
synapse assembly GO:0007416 143 0.020
negative regulation of cell communication GO:0010648 223 0.020
positive regulation of developmental process GO:0051094 143 0.020
negative regulation of multicellular organismal process GO:0051241 142 0.020
eye photoreceptor cell development GO:0042462 81 0.020
response to oxygen containing compound GO:1901700 200 0.020
negative regulation of biosynthetic process GO:0009890 277 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.020
positive regulation of cellular catabolic process GO:0031331 95 0.020
developmental maturation GO:0021700 172 0.020
organonitrogen compound metabolic process GO:1901564 318 0.020
positive regulation of programmed cell death GO:0043068 62 0.020
segmentation GO:0035282 207 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.019
negative regulation of signal transduction GO:0009968 206 0.019
cell migration GO:0016477 238 0.019
chorion containing eggshell formation GO:0007304 105 0.019
chromosome organization GO:0051276 360 0.019
macromolecule catabolic process GO:0009057 161 0.019
cognition GO:0050890 141 0.019
positive regulation of signal transduction GO:0009967 223 0.019
response to alcohol GO:0097305 95 0.019
nuclear division GO:0000280 332 0.019
ovarian follicle cell development GO:0030707 248 0.019
gland morphogenesis GO:0022612 145 0.018
hindgut development GO:0061525 58 0.018
ion transport GO:0006811 145 0.018
morphogenesis of a polarized epithelium GO:0001738 93 0.018
intracellular transport GO:0046907 228 0.018
neuron projection guidance GO:0097485 241 0.018
spindle organization GO:0007051 253 0.018
camera type eye development GO:0043010 4 0.018
photoreceptor cell differentiation GO:0046530 170 0.018
ras protein signal transduction GO:0007265 88 0.018
regulation of protein localization GO:0032880 76 0.018
purine ribonucleoside metabolic process GO:0046128 127 0.018
blastoderm segmentation GO:0007350 159 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
regulation of cell cycle phase transition GO:1901987 130 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
body morphogenesis GO:0010171 2 0.017
immune response activating signal transduction GO:0002757 2 0.017
establishment of localization in cell GO:0051649 402 0.017
stem cell differentiation GO:0048863 117 0.017
negative regulation of developmental process GO:0051093 201 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
positive regulation of cell migration GO:0030335 2 0.017
purine containing compound catabolic process GO:0072523 112 0.017
modification dependent protein catabolic process GO:0019941 78 0.017
negative regulation of nervous system development GO:0051961 92 0.017
endocytosis GO:0006897 310 0.017
regulation of hydrolase activity GO:0051336 97 0.017
positive regulation of gene expression GO:0010628 290 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
organ growth GO:0035265 56 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
gland development GO:0048732 191 0.016
regulation of gene expression epigenetic GO:0040029 128 0.016
regulation of nucleotide catabolic process GO:0030811 48 0.016
hindgut morphogenesis GO:0007442 58 0.016
regulation of response to stress GO:0080134 200 0.016
positive regulation of endopeptidase activity GO:0010950 26 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
regulation of transport GO:0051049 181 0.016
compound eye photoreceptor development GO:0042051 78 0.016
long term memory GO:0007616 62 0.016
positive regulation of molecular function GO:0044093 136 0.016
covalent chromatin modification GO:0016569 106 0.016
single organism catabolic process GO:0044712 228 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
regulation of cell proliferation GO:0042127 163 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.016
imaginal disc pattern formation GO:0007447 91 0.016
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
malpighian tubule development GO:0072002 64 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
embryonic pattern specification GO:0009880 174 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
limb development GO:0060173 1 0.015
establishment of planar polarity GO:0001736 87 0.015
retina development in camera type eye GO:0060041 4 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
cell death GO:0008219 279 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
anterior posterior pattern specification GO:0009952 136 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
cellular protein catabolic process GO:0044257 83 0.015
negative regulation of cell cycle process GO:0010948 109 0.015
regulation of defense response GO:0031347 102 0.015
axon development GO:0061564 297 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
modification dependent macromolecule catabolic process GO:0043632 79 0.015
regulation of ras protein signal transduction GO:0046578 93 0.015
defense response to bacterium GO:0042742 178 0.015
single organism cellular localization GO:1902580 180 0.015
death GO:0016265 284 0.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
hippo signaling GO:0035329 20 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
regulation of cell cycle process GO:0010564 181 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
regulation of cell cycle GO:0051726 291 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
axis specification GO:0009798 167 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
digestive system development GO:0055123 149 0.014
establishment of tissue polarity GO:0007164 87 0.014
organelle assembly GO:0070925 198 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
kidney development GO:0001822 3 0.014
regulation of growth GO:0040008 233 0.014
stem cell fate commitment GO:0048865 25 0.014
cellular response to external stimulus GO:0071496 66 0.014
leg disc development GO:0035218 92 0.014
establishment of protein localization GO:0045184 163 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
rna processing GO:0006396 147 0.014
developmental cell growth GO:0048588 52 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
store operated calcium entry GO:0002115 3 0.014
regulation of cell death GO:0010941 173 0.014
protein transport GO:0015031 155 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
regulation of programmed cell death GO:0043067 152 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
histone modification GO:0016570 106 0.013
chemotaxis GO:0006935 249 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
dendrite morphogenesis GO:0048813 199 0.013
defense response to other organism GO:0098542 225 0.013
connective tissue development GO:0061448 3 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of innate immune response GO:0045088 71 0.013
purine containing compound metabolic process GO:0072521 155 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
regulation of organelle organization GO:0033043 196 0.013
axonogenesis GO:0007409 290 0.013
spermatid development GO:0007286 98 0.013
microtubule organizing center organization GO:0031023 168 0.013
head development GO:0060322 135 0.013
negative regulation of immune system process GO:0002683 50 0.013
salivary gland histolysis GO:0035070 88 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
endomembrane system organization GO:0010256 119 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.013
cellular protein localization GO:0034613 160 0.013
regulation of phosphorylation GO:0042325 147 0.013
dna damage checkpoint GO:0000077 78 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
autophagic cell death GO:0048102 83 0.013
cellular macromolecule localization GO:0070727 220 0.013
gene silencing GO:0016458 138 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
stem cell fate specification GO:0048866 2 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
renal tubule development GO:0061326 64 0.013
protein phosphorylation GO:0006468 169 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
positive regulation of mapk cascade GO:0043410 63 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
negative regulation of cell cycle phase transition GO:1901988 103 0.013
memory GO:0007613 94 0.013
protein processing GO:0016485 68 0.013
pyridine containing compound metabolic process GO:0072524 3 0.013
regulation of immune system process GO:0002682 176 0.013
regulation of organ morphogenesis GO:2000027 78 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.012
positive regulation of transport GO:0051050 92 0.012
cytoplasmic transport GO:0016482 130 0.012
biological adhesion GO:0022610 138 0.012
embryonic axis specification GO:0000578 107 0.012
wnt signaling pathway GO:0016055 98 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
single organism biosynthetic process GO:0044711 206 0.012
nucleotide catabolic process GO:0009166 109 0.012
negative regulation of cell cycle GO:0045786 116 0.012
carbohydrate metabolic process GO:0005975 82 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
positive regulation of cell development GO:0010720 61 0.012
dorsal appendage formation GO:0046843 47 0.012
neural precursor cell proliferation GO:0061351 75 0.012
nucleoside catabolic process GO:0009164 112 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
tube development GO:0035295 244 0.012
immune response GO:0006955 246 0.012
chromatin organization GO:0006325 207 0.012
establishment of ommatidial planar polarity GO:0042067 49 0.012
salt aversion GO:0035199 3 0.012
camera type eye morphogenesis GO:0048593 2 0.012
response to radiation GO:0009314 155 0.012
heterocycle catabolic process GO:0046700 166 0.012
imaginal disc derived wing vein specification GO:0007474 48 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
sensory perception GO:0007600 196 0.012
oocyte development GO:0048599 124 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
regulation of actin cytoskeleton organization GO:0032956 42 0.012
renal system development GO:0072001 72 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
regulation of response to external stimulus GO:0032101 115 0.012
cell recognition GO:0008037 102 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.011
response to glucose GO:0009749 2 0.011
nephron epithelium development GO:0072009 3 0.011
mrna metabolic process GO:0016071 124 0.011
tissue migration GO:0090130 155 0.011
organophosphate metabolic process GO:0019637 195 0.011
regulation of cellular protein catabolic process GO:1903362 44 0.011
cell cycle phase transition GO:0044770 140 0.011
photoreceptor cell axon guidance GO:0072499 23 0.011
chromatin remodeling GO:0006338 72 0.011
regulation of organ growth GO:0046620 42 0.011
mesodermal cell migration GO:0008078 7 0.011
centrosome organization GO:0051297 163 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
chromosome separation GO:0051304 42 0.011
nephron development GO:0072006 3 0.011
gtp catabolic process GO:0006184 72 0.011
cell cycle checkpoint GO:0000075 95 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
negative regulation of cell proliferation GO:0008285 69 0.011
organophosphate catabolic process GO:0046434 112 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
positive regulation of multi organism process GO:0043902 40 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
regulation of gene silencing GO:0060968 63 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
regulation of developmental growth GO:0048638 174 0.011
dna integrity checkpoint GO:0031570 81 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.011
peptide metabolic process GO:0006518 80 0.011
guanosine containing compound catabolic process GO:1901069 74 0.011
mesenchymal cell development GO:0014031 1 0.011
response to organophosphorus GO:0046683 2 0.011
response to starvation GO:0042594 97 0.011
triglyceride biosynthetic process GO:0019432 2 0.011
skeletal muscle fiber development GO:0048741 3 0.011
regulation of autophagy GO:0010506 62 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
oocyte construction GO:0007308 112 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
positive regulation of response to external stimulus GO:0032103 44 0.010
cell division GO:0051301 248 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
tripartite regional subdivision GO:0007351 103 0.010
spindle assembly GO:0051225 80 0.010
axon guidance GO:0007411 233 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
dna metabolic process GO:0006259 227 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.010
positive regulation of peptidase activity GO:0010952 29 0.010
locomotory behavior GO:0007626 176 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
tissue death GO:0016271 102 0.010
response to monosaccharide GO:0034284 4 0.010
oocyte differentiation GO:0009994 145 0.010
negative regulation of rna biosynthetic process GO:1902679 240 0.010
peptidyl amino acid modification GO:0018193 105 0.010
malpighian tubule morphogenesis GO:0007443 44 0.010
response to ethanol GO:0045471 59 0.010
activation of innate immune response GO:0002218 4 0.010
photoreceptor cell fate commitment GO:0046552 41 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010
intracellular protein transport GO:0006886 104 0.010

ppa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.010
disease of metabolism DOID:0014667 0 0.010
cardiovascular system disease DOID:1287 0 0.010