Drosophila melanogaster

61 known processes

rdgA (Dmel_CG42667)

retinal degeneration A

(Aliases: CG42667,Dmel_CG12660,Dmel_CG34344,DGK2,DGK,x35,CG15352,Dmel\CG42667,dDGK2,Dmel_CG10966,CG12660,CG34344,CG10966,Dmel_CG15352)

rdgA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of light stimulus GO:0009583 58 1.000
sensory perception of sound GO:0007605 56 0.999
phototransduction GO:0007602 52 0.999
phototransduction visible light GO:0007603 27 0.991
sensory perception GO:0007600 196 0.991
detection of abiotic stimulus GO:0009582 66 0.983
detection of stimulus GO:0051606 156 0.971
sensory perception of mechanical stimulus GO:0050954 72 0.969
detection of visible light GO:0009584 38 0.944
photoreceptor cell differentiation GO:0046530 170 0.927
cellular response to light stimulus GO:0071482 37 0.921
regulation of rhodopsin mediated signaling pathway GO:0022400 17 0.839
light induced release of internally sequestered calcium ion GO:0008377 1 0.822
neurological system process GO:0050877 358 0.810
rhodopsin mediated signaling pathway GO:0016056 21 0.747
g protein coupled receptor signaling pathway GO:0007186 136 0.693
detection of external stimulus GO:0009581 66 0.681
response to radiation GO:0009314 155 0.673
cellular response to abiotic stimulus GO:0071214 58 0.591
morphogenesis of a polarized epithelium GO:0001738 93 0.442
cellular response to radiation GO:0071478 52 0.384
regulation of response to external stimulus GO:0032101 115 0.339
sensory organ morphogenesis GO:0090596 260 0.319
determination of adult lifespan GO:0008340 137 0.277
regulation of intracellular signal transduction GO:1902531 236 0.276
eye morphogenesis GO:0048592 260 0.268
eye photoreceptor cell differentiation GO:0001754 145 0.261
eye development GO:0001654 323 0.257
response to light stimulus GO:0009416 124 0.252
compound eye development GO:0048749 307 0.240
tissue morphogenesis GO:0048729 297 0.236
cell projection assembly GO:0030031 94 0.221
response to abiotic stimulus GO:0009628 341 0.194
cellular response to chemical stimulus GO:0070887 199 0.188
multicellular organismal aging GO:0010259 140 0.178
taxis GO:0042330 304 0.173
lipid metabolic process GO:0006629 121 0.169
detection of stimulus involved in sensory perception GO:0050906 92 0.167
cell cell junction assembly GO:0007043 38 0.157
thermotaxis GO:0043052 16 0.146
multi multicellular organism process GO:0044706 123 0.138
regulation of localization GO:0032879 275 0.134
death GO:0016265 284 0.125
regulation of catabolic process GO:0009894 170 0.120
negative regulation of cellular biosynthetic process GO:0031327 277 0.119
regulation of gtpase activity GO:0043087 44 0.117
olfactory behavior GO:0042048 97 0.116
camera type eye development GO:0043010 4 0.110
programmed cell death GO:0012501 257 0.108
olfactory learning GO:0008355 56 0.105
response to organic substance GO:0010033 284 0.101
cellular ketone metabolic process GO:0042180 24 0.097
establishment of localization in cell GO:0051649 402 0.096
response to monosaccharide GO:0034284 4 0.095
organic substance catabolic process GO:1901575 308 0.094
cellular response to organic substance GO:0071310 132 0.094
eye antennal disc morphogenesis GO:0007455 34 0.093
developmental pigmentation GO:0048066 68 0.093
establishment of planar polarity GO:0001736 87 0.093
phototransduction uv GO:0007604 5 0.092
small molecule metabolic process GO:0044281 305 0.091
establishment of tissue polarity GO:0007164 87 0.089
response to uv GO:0009411 24 0.088
learning GO:0007612 75 0.086
regulation of growth GO:0040008 233 0.084
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.083
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.083
regulation of multicellular organismal development GO:2000026 414 0.082
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.081
cell maturation GO:0048469 144 0.081
establishment or maintenance of cell polarity GO:0007163 167 0.080
response to oxygen containing compound GO:1901700 200 0.080
eye antennal disc development GO:0035214 60 0.079
brain development GO:0007420 120 0.079
digestive system development GO:0055123 149 0.077
gliogenesis GO:0042063 80 0.075
transcription from rna polymerase ii promoter GO:0006366 368 0.075
central nervous system development GO:0007417 201 0.073
positive regulation of nucleoside metabolic process GO:0045979 47 0.073
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.072
phospholipase c inhibiting g protein coupled receptor signaling pathway GO:0030845 2 0.071
intracellular signal transduction GO:0035556 300 0.070
response to temperature stimulus GO:0009266 106 0.070
cell death GO:0008219 279 0.069
positive regulation of cellular biosynthetic process GO:0031328 316 0.068
guanosine containing compound catabolic process GO:1901069 74 0.066
positive regulation of gtpase activity GO:0043547 43 0.065
retinal cell programmed cell death GO:0046666 25 0.064
regulation of cell death GO:0010941 173 0.062
deactivation of rhodopsin mediated signaling GO:0016059 17 0.062
cell migration GO:0016477 238 0.061
regulation of cellular component movement GO:0051270 42 0.061
rho protein signal transduction GO:0007266 14 0.059
compound eye photoreceptor development GO:0042051 78 0.058
single organism intracellular transport GO:1902582 207 0.057
pigmentation GO:0043473 75 0.055
negative regulation of retinal cell programmed cell death GO:0046671 7 0.055
gtp metabolic process GO:0046039 72 0.055
gtp catabolic process GO:0006184 72 0.052
lipid localization GO:0010876 54 0.052
localization of cell GO:0051674 257 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.051
negative regulation of rna biosynthetic process GO:1902679 240 0.050
purine nucleoside triphosphate catabolic process GO:0009146 108 0.050
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.050
cellular response to extracellular stimulus GO:0031668 64 0.049
positive regulation of biosynthetic process GO:0009891 316 0.049
nucleotide metabolic process GO:0009117 161 0.049
calcium ion transmembrane transport GO:0070588 17 0.049
regulation of transport GO:0051049 181 0.049
negative regulation of gene expression GO:0010629 387 0.048
carotenoid metabolic process GO:0016116 1 0.047
catabolic process GO:0009056 409 0.047
organic cyclic compound catabolic process GO:1901361 168 0.046
divalent inorganic cation transport GO:0072511 30 0.046
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.046
anatomical structure homeostasis GO:0060249 97 0.046
compound eye photoreceptor cell differentiation GO:0001751 140 0.046
cellular lipid metabolic process GO:0044255 83 0.045
apoptotic process GO:0006915 159 0.045
compound eye cone cell fate commitment GO:0042676 5 0.045
enzyme linked receptor protein signaling pathway GO:0007167 179 0.044
intracellular transport GO:0046907 228 0.043
chemotaxis GO:0006935 249 0.043
axon development GO:0061564 297 0.042
response to hormone GO:0009725 45 0.042
eye pigment metabolic process GO:0042441 33 0.042
neuron fate commitment GO:0048663 50 0.041
entrainment of circadian clock GO:0009649 16 0.041
negative regulation of signaling GO:0023057 219 0.041
cellular response to oxygen containing compound GO:1901701 79 0.041
phospholipase c activating rhodopsin mediated signaling pathway GO:0030265 1 0.040
positive regulation of rna metabolic process GO:0051254 271 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.039
response to organonitrogen compound GO:0010243 75 0.039
response to endogenous stimulus GO:0009719 119 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.039
regulation of nucleoside metabolic process GO:0009118 50 0.039
regulation of nucleotide catabolic process GO:0030811 48 0.038
response to inorganic substance GO:0010035 44 0.038
oxoacid metabolic process GO:0043436 103 0.037
positive regulation of neuron apoptotic process GO:0043525 1 0.036
cellular response to hormone stimulus GO:0032870 44 0.036
regulation of anatomical structure morphogenesis GO:0022603 242 0.036
compound eye morphogenesis GO:0001745 249 0.036
heterocycle catabolic process GO:0046700 166 0.036
positive regulation of catabolic process GO:0009896 105 0.035
metal ion homeostasis GO:0055065 44 0.035
response to nutrient levels GO:0031667 114 0.035
cellular protein modification process GO:0006464 438 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.034
photoreceptor cell fate commitment GO:0046552 41 0.034
visual perception GO:0007601 9 0.034
detection of light stimulus involved in sensory perception GO:0050962 9 0.033
regulation of retinal cell programmed cell death GO:0046668 18 0.033
neuron projection guidance GO:0097485 241 0.033
negative regulation of rna metabolic process GO:0051253 251 0.032
retina development in camera type eye GO:0060041 4 0.032
negative regulation of multicellular organismal process GO:0051241 142 0.032
glial cell differentiation GO:0010001 35 0.032
response to nitrogen compound GO:1901698 90 0.032
tube morphogenesis GO:0035239 191 0.031
regionalization GO:0003002 416 0.031
regulation of mitotic cell cycle GO:0007346 190 0.031
negative regulation of cell death GO:0060548 81 0.031
positive regulation of transport GO:0051050 92 0.031
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
response to insulin GO:0032868 29 0.030
cellular component assembly involved in morphogenesis GO:0010927 151 0.030
ribonucleotide catabolic process GO:0009261 109 0.029
regulation of cellular amine metabolic process GO:0033238 3 0.029
cell motility GO:0048870 251 0.029
oocyte maturation GO:0001556 3 0.029
positive regulation of nucleotide catabolic process GO:0030813 46 0.029
microtubule organizing center organization GO:0031023 168 0.028
ribonucleoside metabolic process GO:0009119 127 0.028
negative regulation of neuron death GO:1901215 18 0.028
single organism catabolic process GO:0044712 228 0.028
maintenance of location GO:0051235 73 0.028
camera type eye morphogenesis GO:0048593 2 0.028
developmental maturation GO:0021700 172 0.027
small gtpase mediated signal transduction GO:0007264 88 0.027
positive regulation of signaling GO:0023056 243 0.027
metarhodopsin inactivation GO:0016060 5 0.027
positive regulation of gene expression GO:0010628 290 0.027
negative regulation of transcription dna templated GO:0045892 237 0.027
photoreceptor cell development GO:0042461 96 0.027
purine nucleotide catabolic process GO:0006195 109 0.027
negative regulation of programmed cell death GO:0043069 72 0.027
cellular nitrogen compound catabolic process GO:0044270 165 0.026
ras protein signal transduction GO:0007265 88 0.026
lateral inhibition GO:0046331 206 0.026
regulation of protein metabolic process GO:0051246 256 0.026
nucleoside triphosphate catabolic process GO:0009143 108 0.026
organophosphate metabolic process GO:0019637 195 0.026
circadian rhythm GO:0007623 105 0.026
positive regulation of gtp catabolic process GO:0033126 43 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
regulation of apoptotic process GO:0042981 130 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
cytosolic calcium ion transport GO:0060401 2 0.025
single organism biosynthetic process GO:0044711 206 0.025
cognition GO:0050890 141 0.025
ribonucleoside catabolic process GO:0042454 112 0.025
organic substance transport GO:0071702 257 0.025
regulation of phosphorylation GO:0042325 147 0.024
negative regulation of cell communication GO:0010648 223 0.024
developmental growth GO:0048589 280 0.024
regulation of catalytic activity GO:0050790 185 0.023
cellular response to endogenous stimulus GO:0071495 80 0.023
positive regulation of ras gtpase activity GO:0032320 36 0.023
organelle fission GO:0048285 340 0.023
purine ribonucleoside metabolic process GO:0046128 127 0.023
nucleobase containing small molecule metabolic process GO:0055086 174 0.023
vitamin metabolic process GO:0006766 2 0.023
salivary gland development GO:0007431 162 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
adaptation of signaling pathway GO:0023058 3 0.023
cellular amino acid metabolic process GO:0006520 61 0.022
tetraterpenoid metabolic process GO:0016108 1 0.022
cell junction organization GO:0034330 57 0.022
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.022
tissue migration GO:0090130 155 0.022
nucleobase containing compound catabolic process GO:0034655 165 0.022
skin development GO:0043588 65 0.022
protein complex biogenesis GO:0070271 201 0.022
cilium assembly GO:0042384 38 0.021
regulation of cellular localization GO:0060341 136 0.021
positive regulation of nucleotide metabolic process GO:0045981 55 0.021
cilium morphogenesis GO:0060271 39 0.021
organonitrogen compound metabolic process GO:1901564 318 0.021
compound eye retinal cell programmed cell death GO:0046667 23 0.021
locomotory behavior GO:0007626 176 0.021
nucleoside phosphate catabolic process GO:1901292 110 0.021
aging GO:0007568 143 0.021
macromolecular complex assembly GO:0065003 256 0.021
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
positive regulation of molecular function GO:0044093 136 0.021
intercellular transport GO:0010496 2 0.021
phosphorylation GO:0016310 294 0.020
positive regulation of developmental growth GO:0048639 62 0.020
regulation of hydrolase activity GO:0051336 97 0.020
positive regulation of rna biosynthetic process GO:1902680 266 0.020
positive regulation of cellular catabolic process GO:0031331 95 0.020
epithelial tube morphogenesis GO:0060562 88 0.020
regulation of programmed cell death GO:0043067 152 0.019
cellular catabolic process GO:0044248 372 0.019
regulation of epithelial cell differentiation GO:0030856 4 0.019
response to endoplasmic reticulum stress GO:0034976 28 0.019
cell proliferation GO:0008283 299 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.018
tube development GO:0035295 244 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
chemosensory behavior GO:0007635 106 0.018
amine metabolic process GO:0009308 12 0.018
axon cargo transport GO:0008088 29 0.018
regulation of cell development GO:0060284 215 0.018
photoreceptor cell maintenance GO:0045494 11 0.018
detection of light stimulus involved in visual perception GO:0050908 6 0.018
rhythmic process GO:0048511 106 0.018
germarium derived egg chamber formation GO:0007293 101 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
eye photoreceptor cell development GO:0042462 81 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
retina morphogenesis in camera type eye GO:0060042 2 0.017
axonogenesis GO:0007409 290 0.017
regulation of gtp catabolic process GO:0033124 44 0.017
regulation of neuron apoptotic process GO:0043523 16 0.017
cellular response to peptide GO:1901653 28 0.017
regulation of cellular component size GO:0032535 98 0.017
signal release GO:0023061 49 0.017
negative regulation of developmental process GO:0051093 201 0.017
aromatic compound catabolic process GO:0019439 166 0.017
glycosyl compound metabolic process GO:1901657 127 0.016
regulation of secretion by cell GO:1903530 39 0.016
single organism behavior GO:0044708 391 0.016
regulation of cell cycle g1 s phase transition GO:1902806 23 0.016
nucleotide catabolic process GO:0009166 109 0.016
protein modification process GO:0036211 438 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
learning or memory GO:0007611 141 0.016
female germ line cyst formation GO:0048135 42 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
regulation of cell proliferation GO:0042127 163 0.016
second mitotic wave involved in compound eye morphogenesis GO:0016330 7 0.016
single organism cell adhesion GO:0098602 47 0.015
gland development GO:0048732 191 0.015
nucleoside metabolic process GO:0009116 127 0.015
eye photoreceptor cell fate commitment GO:0042706 37 0.015
establishment of nucleus localization GO:0040023 26 0.015
calcium ion transport GO:0006816 24 0.015
axon guidance GO:0007411 233 0.015
negative regulation of signal transduction GO:0009968 206 0.015
adherens junction organization GO:0034332 27 0.015
oocyte development GO:0048599 124 0.015
macromolecule catabolic process GO:0009057 161 0.015
calcium ion transport into cytosol GO:0060402 2 0.015
negative regulation of intracellular signal transduction GO:1902532 57 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
organelle localization GO:0051640 148 0.015
response to glucose GO:0009749 2 0.015
gland morphogenesis GO:0022612 145 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
regulation of cell size GO:0008361 63 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
cellular amine metabolic process GO:0044106 12 0.014
regulation of vesicle mediated transport GO:0060627 59 0.014
regulation of purine nucleotide metabolic process GO:1900542 62 0.014
regulation of cysteine type endopeptidase activity GO:2000116 27 0.014
exocrine system development GO:0035272 162 0.014
mapk cascade GO:0000165 107 0.014
phagocytosis GO:0006909 215 0.014
head development GO:0060322 135 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
secretion GO:0046903 109 0.014
divalent metal ion transport GO:0070838 26 0.014
positive regulation of neurogenesis GO:0050769 41 0.014
acid secretion GO:0046717 1 0.014
positive regulation of developmental process GO:0051094 143 0.014
developmental programmed cell death GO:0010623 138 0.014
purine nucleoside catabolic process GO:0006152 112 0.013
cellular protein localization GO:0034613 160 0.013
leg disc development GO:0035218 92 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
regulation of secretion GO:0051046 44 0.013
cytoplasmic transport GO:0016482 130 0.013
regulation of microtubule based process GO:0032886 49 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
response to hexose GO:0009746 3 0.013
regulation of nervous system development GO:0051960 248 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
single organism cellular localization GO:1902580 180 0.013
positive regulation of rho gtpase activity GO:0032321 19 0.013
cytoskeleton dependent intracellular transport GO:0030705 44 0.013
regulation of molecular function GO:0065009 217 0.013
purine containing compound catabolic process GO:0072523 112 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
cellular response to starvation GO:0009267 61 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
pigment metabolic process involved in pigmentation GO:0043474 33 0.012
lipid biosynthetic process GO:0008610 46 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
regulation of protein phosphorylation GO:0001932 64 0.012
response to organophosphorus GO:0046683 2 0.012
morphogenesis of embryonic epithelium GO:0016331 94 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
regulation of developmental growth GO:0048638 174 0.012
cellular response to carbohydrate stimulus GO:0071322 4 0.012
regulation of cell motility GO:2000145 23 0.012
organophosphate catabolic process GO:0046434 112 0.012
anion transport GO:0006820 41 0.012
regulation of locomotion GO:0040012 42 0.012
compound eye photoreceptor fate commitment GO:0001752 36 0.012
meiotic cell cycle GO:0051321 171 0.012
regulation of neuron projection development GO:0010975 69 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
regulation of cell migration GO:0030334 22 0.012
fat soluble vitamin biosynthetic process GO:0042362 1 0.012
growth GO:0040007 359 0.011
regulation of meiosis GO:0040020 3 0.011
telencephalon development GO:0021537 2 0.011
nitrogen compound transport GO:0071705 85 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
negative regulation of gene expression epigenetic GO:0045814 77 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
embryonic morphogenesis GO:0048598 206 0.011
regulation of sequestering of calcium ion GO:0051282 3 0.011
regulation of rac protein signal transduction GO:0035020 3 0.011
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
monocarboxylic acid transport GO:0015718 3 0.011
response to organic cyclic compound GO:0014070 89 0.011
regulation of erk1 and erk2 cascade GO:0070372 39 0.011
regulation of organelle organization GO:0033043 196 0.011
positive regulation of cell motility GO:2000147 3 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
cellular response to uv GO:0034644 12 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
cell cycle g1 s phase transition GO:0044843 31 0.011
chaeta development GO:0022416 97 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.010
glial cell development GO:0021782 27 0.010
positive regulation of cell communication GO:0010647 250 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
lipid storage GO:0019915 38 0.010
multi organism behavior GO:0051705 175 0.010
hindbrain development GO:0030902 2 0.010
release of sequestered calcium ion into cytosol GO:0051209 1 0.010
cell adhesion GO:0007155 136 0.010
protein phosphorylation GO:0006468 169 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010

rdgA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016