Drosophila melanogaster

81 known processes

NetA (Dmel_CG18657)

Netrin-A

(Aliases: netrin A,CG18657,Dmel\CG18657,netA,netrin,CT27014,NetrinA)

NetA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axonogenesis GO:0007409 290 0.898
neuron projection guidance GO:0097485 241 0.613
central nervous system development GO:0007417 201 0.605
Zebrafish
axon development GO:0061564 297 0.599
motor neuron axon guidance GO:0008045 58 0.491
chemotaxis GO:0006935 249 0.394
axon guidance GO:0007411 233 0.363
regulation of cell development GO:0060284 215 0.350
regulation of cell differentiation GO:0045595 302 0.300
localization of cell GO:0051674 257 0.289
cell recognition GO:0008037 102 0.221
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.213
taxis GO:0042330 304 0.212
gland development GO:0048732 191 0.208
Mouse Fly
head development GO:0060322 135 0.200
Zebrafish
neuron recognition GO:0008038 101 0.190
Fly
regulation of nervous system development GO:0051960 248 0.187
cell motility GO:0048870 251 0.176
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.176
regulation of neurogenesis GO:0050767 158 0.172
regulation of multicellular organismal development GO:2000026 414 0.162
cell cell adhesion GO:0098609 26 0.156
lateral inhibition GO:0046331 206 0.134
cell maturation GO:0048469 144 0.132
positive regulation of rna metabolic process GO:0051254 271 0.129
branching morphogenesis of an epithelial tube GO:0048754 45 0.125
Zebrafish
regulation of neuron projection development GO:0010975 69 0.122
negative regulation of cellular biosynthetic process GO:0031327 277 0.121
sensory organ morphogenesis GO:0090596 260 0.120
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.106
regulation of axon extension involved in axon guidance GO:0048841 4 0.100
brain development GO:0007420 120 0.098
Zebrafish
negative regulation of developmental process GO:0051093 201 0.097
Zebrafish Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.097
dendrite morphogenesis GO:0048813 199 0.095
actin filament based process GO:0030029 220 0.095
embryonic pattern specification GO:0009880 174 0.093
regulation of intracellular signal transduction GO:1902531 236 0.092
camera type eye development GO:0043010 4 0.091
negative regulation of biosynthetic process GO:0009890 277 0.089
tube development GO:0035295 244 0.089
Zebrafish Mouse
positive regulation of response to stimulus GO:0048584 323 0.087
glial cell migration GO:0008347 31 0.086
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.084
regulation of neuron differentiation GO:0045664 103 0.084
morphogenesis of a branching epithelium GO:0061138 45 0.084
Zebrafish
synaptic target recognition GO:0008039 45 0.083
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.080
epithelial cell differentiation GO:0030855 322 0.080
tissue morphogenesis GO:0048729 297 0.079
Zebrafish Mouse
forebrain development GO:0030900 2 0.079
Zebrafish
kidney epithelium development GO:0072073 3 0.076
positive regulation of rna biosynthetic process GO:1902680 266 0.075
biological adhesion GO:0022610 138 0.074
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.072
kidney development GO:0001822 3 0.072
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.072
actin cytoskeleton organization GO:0030036 206 0.071
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.071
regulation of cellular component biogenesis GO:0044087 201 0.071
bolwig s organ development GO:0055034 8 0.070
cell cell signaling involved in cell fate commitment GO:0045168 210 0.066
negative regulation of rna biosynthetic process GO:1902679 240 0.064
dendrite guidance GO:0070983 21 0.063
eye development GO:0001654 323 0.061
nephron morphogenesis GO:0072028 3 0.060
retinal ganglion cell axon guidance GO:0031290 12 0.059
mesoderm development GO:0007498 78 0.059
morphogenesis of an epithelium GO:0002009 276 0.058
Zebrafish Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.057
negative regulation of nucleic acid templated transcription GO:1903507 240 0.057
response to external biotic stimulus GO:0043207 293 0.057
imaginal disc derived appendage development GO:0048737 399 0.056
regulation of localization GO:0032879 275 0.056
regulation of cell projection organization GO:0031344 92 0.056
positive regulation of nucleic acid templated transcription GO:1903508 266 0.055
nephron epithelium development GO:0072009 3 0.055
regulation of anatomical structure morphogenesis GO:0022603 242 0.055
regulation of response to stress GO:0080134 200 0.055
signal transduction by phosphorylation GO:0023014 107 0.054
negative regulation of rna metabolic process GO:0051253 251 0.054
exocrine system development GO:0035272 162 0.053
Fly
regulation of cell morphogenesis GO:0022604 163 0.052
regulation of cell death GO:0010941 173 0.052
Zebrafish
ameboidal type cell migration GO:0001667 151 0.051
cell migration GO:0016477 238 0.050
salivary gland morphogenesis GO:0007435 145 0.050
organonitrogen compound metabolic process GO:1901564 318 0.050
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.049
dna metabolic process GO:0006259 227 0.048
appendage development GO:0048736 401 0.048
response to biotic stimulus GO:0009607 294 0.047
gland morphogenesis GO:0022612 145 0.047
Mouse
intracellular signal transduction GO:0035556 300 0.047
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.046
connective tissue development GO:0061448 3 0.046
immune system process GO:0002376 347 0.046
epithelium migration GO:0090132 148 0.045
positive regulation of axonogenesis GO:0050772 2 0.042
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.042
dorsal closure GO:0007391 79 0.042
regulation of phosphorus metabolic process GO:0051174 210 0.041
death GO:0016265 284 0.041
Zebrafish
body morphogenesis GO:0010171 2 0.041
negative regulation of transcription dna templated GO:0045892 237 0.041
morphogenesis of embryonic epithelium GO:0016331 94 0.041
catabolic process GO:0009056 409 0.041
dendrite development GO:0016358 204 0.040
olfactory bulb axon guidance GO:0071678 3 0.040
Zebrafish
phosphorylation GO:0016310 294 0.039
epithelial cell migration GO:0010631 148 0.039
positive regulation of transcription dna templated GO:0045893 266 0.039
axon extension GO:0048675 32 0.039
Zebrafish Mouse
epithelial tube morphogenesis GO:0060562 88 0.039
Zebrafish Mouse
negative regulation of gene expression GO:0010629 387 0.038
negative regulation of cell differentiation GO:0045596 143 0.038
Mouse
mushroom body development GO:0016319 70 0.038
columnar cuboidal epithelial cell development GO:0002066 249 0.038
regulation of small gtpase mediated signal transduction GO:0051056 93 0.038
retina development in camera type eye GO:0060041 4 0.038
positive regulation of multicellular organismal process GO:0051240 143 0.037
Mouse
organelle fission GO:0048285 340 0.037
positive regulation of signaling GO:0023056 243 0.037
ras protein signal transduction GO:0007265 88 0.036
photoreceptor cell axon guidance GO:0072499 23 0.036
developmental programmed cell death GO:0010623 138 0.036
response to lipopolysaccharide GO:0032496 4 0.036
epithelial cell development GO:0002064 274 0.036
positive regulation of cell development GO:0010720 61 0.036
Mouse
cardiovascular system development GO:0072358 82 0.036
Zebrafish
spermatogenesis GO:0007283 200 0.035
actin filament organization GO:0007015 126 0.035
positive regulation of cellular component organization GO:0051130 156 0.035
Mouse
respiratory system development GO:0060541 213 0.034
myoblast fusion GO:0007520 43 0.034
salivary gland development GO:0007431 162 0.034
Fly
programmed cell death GO:0012501 257 0.034
Zebrafish
segmentation GO:0035282 207 0.034
regulation of molecular function GO:0065009 217 0.033
positive regulation of biosynthetic process GO:0009891 316 0.033
cell death GO:0008219 279 0.033
Zebrafish
anterior posterior pattern specification GO:0009952 136 0.033
cellular catabolic process GO:0044248 372 0.032
dorsal ventral axon guidance GO:0033563 2 0.032
positive regulation of signal transduction GO:0009967 223 0.032
regulation of protein metabolic process GO:0051246 256 0.032
developmental maturation GO:0021700 172 0.032
regulation of cell cycle process GO:0010564 181 0.031
small gtpase mediated signal transduction GO:0007264 88 0.031
regulation of cell proliferation GO:0042127 163 0.031
Mouse
myotube differentiation GO:0014902 46 0.031
axonal defasciculation GO:0007414 12 0.031
muscle structure development GO:0061061 224 0.031
blastoderm segmentation GO:0007350 159 0.030
single organism catabolic process GO:0044712 228 0.030
regulation of cellular localization GO:0060341 136 0.030
ovarian follicle cell development GO:0030707 248 0.030
positive regulation of cell differentiation GO:0045597 64 0.030
Mouse
response to other organism GO:0051707 293 0.029
single organism biosynthetic process GO:0044711 206 0.029
leg disc development GO:0035218 92 0.029
small molecule metabolic process GO:0044281 305 0.029
positive regulation of catabolic process GO:0009896 105 0.029
protein modification process GO:0036211 438 0.028
ribonucleotide metabolic process GO:0009259 145 0.027
negative regulation of growth GO:0045926 84 0.027
Mouse
regulation of immune system process GO:0002682 176 0.027
cell proliferation GO:0008283 299 0.027
Mouse
positive regulation of axon extension GO:0045773 2 0.027
Mouse
regionalization GO:0003002 416 0.027
Fly
appendage morphogenesis GO:0035107 397 0.027
imaginal disc derived appendage morphogenesis GO:0035114 395 0.027
positive regulation of gene expression GO:0010628 290 0.027
immune system development GO:0002520 57 0.026
negative chemotaxis GO:0050919 15 0.026
cellular amine metabolic process GO:0044106 12 0.026
positive regulation of neurogenesis GO:0050769 41 0.026
Mouse
regeneration GO:0031099 16 0.026
regulation of apoptotic process GO:0042981 130 0.026
Zebrafish
regulation of response to external stimulus GO:0032101 115 0.026
positive regulation of cell communication GO:0010647 250 0.026
developmental growth GO:0048589 280 0.026
Zebrafish Mouse
extrinsic apoptotic signaling pathway GO:0097191 1 0.026
Zebrafish
camera type eye morphogenesis GO:0048593 2 0.026
developmental cell growth GO:0048588 52 0.025
Zebrafish Mouse
regulation of phosphate metabolic process GO:0019220 210 0.025
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.025
cellular response to chemical stimulus GO:0070887 199 0.025
syncytium formation by plasma membrane fusion GO:0000768 43 0.025
tissue migration GO:0090130 155 0.025
negative regulation of axon extension GO:0030517 3 0.024
Mouse
growth GO:0040007 359 0.024
Zebrafish Mouse
wing disc morphogenesis GO:0007472 344 0.024
morphogenesis of a polarized epithelium GO:0001738 93 0.024
telencephalon development GO:0021537 2 0.024
Zebrafish
regulation of protein complex assembly GO:0043254 42 0.024
negative regulation of multicellular organismal process GO:0051241 142 0.024
Zebrafish Mouse
regulation of catabolic process GO:0009894 170 0.024
tissue death GO:0016271 102 0.023
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.023
cellular amide metabolic process GO:0043603 80 0.023
bolwig s organ morphogenesis GO:0001746 8 0.022
organic substance catabolic process GO:1901575 308 0.022
regulation of synapse organization GO:0050807 110 0.022
positive regulation of molecular function GO:0044093 136 0.022
organonitrogen compound catabolic process GO:1901565 128 0.022
central nervous system projection neuron axonogenesis GO:0021952 6 0.022
Zebrafish
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.022
Mouse
neuron projection extension GO:1990138 32 0.022
Zebrafish Mouse
positive regulation of phosphorus metabolic process GO:0010562 139 0.022
positive regulation of immune system process GO:0002684 68 0.021
organic acid metabolic process GO:0006082 103 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
developmental growth involved in morphogenesis GO:0060560 65 0.021
Zebrafish Mouse
regulation of catalytic activity GO:0050790 185 0.021
negative regulation of programmed cell death GO:0043069 72 0.021
Zebrafish
positive regulation of proteolysis GO:0045862 52 0.021
stem cell differentiation GO:0048863 117 0.021
cell cycle phase transition GO:0044770 140 0.021
establishment of tissue polarity GO:0007164 87 0.021
myotube cell development GO:0014904 3 0.021
gonad development GO:0008406 50 0.020
organ formation GO:0048645 39 0.020
Fly
positive regulation of nervous system development GO:0051962 69 0.020
Mouse
negative regulation of neurogenesis GO:0050768 53 0.020
Mouse
hindbrain development GO:0030902 2 0.020
neuron fate commitment GO:0048663 50 0.020
Zebrafish
negative regulation of cellular component organization GO:0051129 108 0.020
Mouse
cellular response to oxygen containing compound GO:1901701 79 0.020
response to oxygen containing compound GO:1901700 200 0.019
outflow tract morphogenesis GO:0003151 4 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
muscle organ development GO:0007517 127 0.019
embryonic axis specification GO:0000578 107 0.019
imaginal disc derived wing morphogenesis GO:0007476 337 0.019
regulation of ras protein signal transduction GO:0046578 93 0.019
spinal cord development GO:0021510 1 0.019
synapse assembly GO:0007416 143 0.019
defense response GO:0006952 300 0.019
germ cell migration GO:0008354 43 0.019
stem cell development GO:0048864 79 0.019
leg disc morphogenesis GO:0007478 80 0.019
nuclear division GO:0000280 332 0.019
chemical homeostasis GO:0048878 92 0.019
tube morphogenesis GO:0035239 191 0.018
Zebrafish Mouse
syncytium formation GO:0006949 43 0.018
establishment or maintenance of cell polarity GO:0007163 167 0.018
digestive tract development GO:0048565 149 0.018
regulation of hydrolase activity GO:0051336 97 0.018
convergent extension GO:0060026 2 0.018
amine metabolic process GO:0009308 12 0.018
chromatin organization GO:0006325 207 0.018
positive regulation of hydrolase activity GO:0051345 78 0.018
cell adhesion GO:0007155 136 0.018
Mouse
neural retina development GO:0003407 4 0.018
wnt signaling pathway GO:0016055 98 0.018
gastrulation GO:0007369 70 0.018
inositol lipid mediated signaling GO:0048017 4 0.018
organophosphate metabolic process GO:0019637 195 0.018
regulation of epithelial cell differentiation GO:0030856 4 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.017
homeostatic process GO:0042592 199 0.017
cellular protein modification process GO:0006464 438 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
axon choice point recognition GO:0016198 26 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
nephron development GO:0072006 3 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.017
rho protein signal transduction GO:0007266 14 0.017
response to bacterium GO:0009617 198 0.017
eye morphogenesis GO:0048592 260 0.017
negative regulation of nervous system development GO:0051961 92 0.016
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 4 0.016
circulatory system development GO:0072359 82 0.016
Zebrafish
negative regulation of cell death GO:0060548 81 0.016
Zebrafish
establishment of localization in cell GO:0051649 402 0.016
Mouse
morphogenesis of a branching structure GO:0001763 45 0.016
Zebrafish
axis elongation GO:0003401 3 0.016
positive regulation of organelle organization GO:0010638 65 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
eye pigmentation GO:0048069 43 0.016
mrna metabolic process GO:0016071 124 0.015
axis specification GO:0009798 167 0.015
negative regulation of cell communication GO:0010648 223 0.015
Zebrafish
long chain fatty acid metabolic process GO:0001676 3 0.015
regulation of dendrite morphogenesis GO:0048814 28 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
embryonic morphogenesis GO:0048598 206 0.015
Mouse
actin filament bundle organization GO:0061572 28 0.015
epidermis development GO:0008544 65 0.015
negative regulation of cell development GO:0010721 62 0.015
Mouse
positive regulation of cellular catabolic process GO:0031331 95 0.015
organic substance transport GO:0071702 257 0.014
regulation of dendrite development GO:0050773 37 0.014
anterior commissure morphogenesis GO:0021960 2 0.014
Zebrafish
regulation of axon guidance GO:1902667 10 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
positive regulation of developmental process GO:0051094 143 0.014
Mouse
axon midline choice point recognition GO:0016199 26 0.014
proteolysis GO:0006508 192 0.014
tripartite regional subdivision GO:0007351 103 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.014
apoptotic process GO:0006915 159 0.014
Zebrafish
development of primary sexual characteristics GO:0045137 50 0.014
response to monosaccharide GO:0034284 4 0.014
androgen metabolic process GO:0008209 1 0.014
gastrulation with mouth forming first GO:0001703 36 0.014
anterior posterior axis specification GO:0009948 109 0.014
urogenital system development GO:0001655 72 0.014
regulation of organelle organization GO:0033043 196 0.014
positive regulation of response to external stimulus GO:0032103 44 0.014
stress activated protein kinase signaling cascade GO:0031098 55 0.014
cellular response to organic substance GO:0071310 132 0.014
convergent extension involved in gastrulation GO:0060027 2 0.013
response to oxidative stress GO:0006979 86 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
cellular ketone metabolic process GO:0042180 24 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
Zebrafish
cuticle development GO:0042335 86 0.013
establishment of planar polarity GO:0001736 87 0.013
embryonic organ development GO:0048568 50 0.013
Mouse
digestive system development GO:0055123 149 0.013
kidney morphogenesis GO:0060993 3 0.013
male gamete generation GO:0048232 201 0.013
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
positive regulation of transport GO:0051050 92 0.013
negative regulation of signal transduction GO:0009968 206 0.013
Zebrafish
response to radiation GO:0009314 155 0.013
regulation of cellular component size GO:0032535 98 0.012
Zebrafish Mouse
single organismal cell cell adhesion GO:0016337 45 0.012
Mouse
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
alcohol metabolic process GO:0006066 25 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
positive regulation of cell migration GO:0030335 2 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
regulation of chemotaxis GO:0050920 12 0.012
regulation of epithelial cell proliferation GO:0050678 4 0.012
response to organic substance GO:0010033 284 0.012
regulation of cell size GO:0008361 63 0.012
Zebrafish Mouse
positive regulation of cell projection organization GO:0031346 29 0.012
Mouse
response to copper ion GO:0046688 4 0.012
regulation of multi organism process GO:0043900 131 0.012
positive regulation of mapk cascade GO:0043410 63 0.012
nephron epithelium morphogenesis GO:0072088 3 0.012
nephron tubule morphogenesis GO:0072078 3 0.012
protein catabolic process GO:0030163 101 0.012
negative regulation of developmental growth GO:0048640 64 0.012
Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
autophagic cell death GO:0048102 83 0.012
protein phosphorylation GO:0006468 169 0.012
limb development GO:0060173 1 0.012
positive regulation of cell motility GO:2000147 3 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.011
gonad morphogenesis GO:0035262 7 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
wound healing GO:0042060 75 0.011
regulation of synapse assembly GO:0051963 94 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
regulation of organ formation GO:0003156 3 0.011
cytosolic calcium ion transport GO:0060401 2 0.011
head involution GO:0008258 35 0.011
mapk cascade GO:0000165 107 0.011
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 8 0.011
single organism intracellular transport GO:1902582 207 0.011
oxoacid metabolic process GO:0043436 103 0.011
lamellipodium assembly GO:0030032 21 0.011
response to organic cyclic compound GO:0014070 89 0.011
regulation of axonogenesis GO:0050770 32 0.010
organic hydroxy compound biosynthetic process GO:1901617 21 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
cell migration involved in gastrulation GO:0042074 9 0.010
regulation of locomotion GO:0040012 42 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
negative regulation of gene expression epigenetic GO:0045814 77 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
macromolecular complex assembly GO:0065003 256 0.010
cell cell junction organization GO:0045216 55 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
positive regulation of cell proliferation GO:0008284 47 0.010
Mouse
regulation of embryonic development GO:0045995 68 0.010

NetA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
sensory system disease DOID:0050155 0 0.018
nervous system disease DOID:863 0 0.018
bone disease DOID:0080001 0 0.012
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012