Drosophila melanogaster

11 known processes

VGAT (Dmel_CG8394)

Vesicular GABA Transporter

(Aliases: CG8394,VIAAT,Dmel\CG8394,vGAT,CG8394.2)

VGAT biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotory behavior GO:0007626 176 0.463
learning or memory GO:0007611 141 0.165
adult behavior GO:0030534 137 0.124
rhythmic process GO:0048511 106 0.084
neurological system process GO:0050877 358 0.076
rhythmic behavior GO:0007622 76 0.075
circadian rhythm GO:0007623 105 0.071
inter male aggressive behavior GO:0002121 60 0.068
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.068
regulation of response to external stimulus GO:0032101 115 0.067
synaptic transmission GO:0007268 288 0.067
apical junction assembly GO:0043297 32 0.066
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.060
regulation of behavior GO:0050795 75 0.060
regulation of circadian sleep wake cycle GO:0042749 25 0.060
negative regulation of rna biosynthetic process GO:1902679 240 0.058
positive regulation of response to stimulus GO:0048584 323 0.057
chromosome organization GO:0051276 360 0.050
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.048
detection of chemical stimulus GO:0009593 93 0.047
negative regulation of signal transduction GO:0009968 206 0.047
regulation of response to stress GO:0080134 200 0.047
cell cell junction organization GO:0045216 55 0.046
heart process GO:0003015 37 0.046
regulation of epithelial cell proliferation GO:0050678 4 0.045
response to biotic stimulus GO:0009607 294 0.045
localization of cell GO:0051674 257 0.044
endocytosis GO:0006897 310 0.043
positive regulation of apoptotic signaling pathway GO:2001235 4 0.043
regulation of immune system process GO:0002682 176 0.042
negative regulation of nucleic acid templated transcription GO:1903507 240 0.042
transcription from rna polymerase ii promoter GO:0006366 368 0.042
phenol containing compound metabolic process GO:0018958 57 0.042
response to other organism GO:0051707 293 0.040
negative regulation of gene expression GO:0010629 387 0.039
circadian sleep wake cycle GO:0042745 28 0.039
regulation of tube architecture open tracheal system GO:0035152 68 0.039
regulation of cell cycle GO:0051726 291 0.038
negative regulation of response to stimulus GO:0048585 258 0.038
organonitrogen compound metabolic process GO:1901564 318 0.037
sensory perception GO:0007600 196 0.036
positive regulation of signal transduction GO:0009967 223 0.036
positive regulation of signaling GO:0023056 243 0.036
ion transport GO:0006811 145 0.036
defense response GO:0006952 300 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.035
forebrain development GO:0030900 2 0.034
response to oxidative stress GO:0006979 86 0.033
chromatin organization GO:0006325 207 0.033
regulation of circadian rhythm GO:0042752 49 0.033
negative regulation of cell communication GO:0010648 223 0.032
regulation of cellular ketone metabolic process GO:0010565 3 0.031
regulation of mitotic cell cycle GO:0007346 190 0.031
ion transmembrane transport GO:0034220 122 0.031
compound eye development GO:0048749 307 0.031
immune response activating signal transduction GO:0002757 2 0.030
head development GO:0060322 135 0.030
circadian behavior GO:0048512 76 0.030
response to temperature stimulus GO:0009266 106 0.030
vesicle mediated transport GO:0016192 381 0.030
adult locomotory behavior GO:0008344 76 0.029
oxoacid metabolic process GO:0043436 103 0.029
l amino acid import GO:0043092 2 0.029
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.029
cellular macromolecule localization GO:0070727 220 0.029
organic substance transport GO:0071702 257 0.029
cellular amine metabolic process GO:0044106 12 0.029
negative regulation of signaling GO:0023057 219 0.028
chromatin modification GO:0016568 147 0.028
organic substance catabolic process GO:1901575 308 0.028
cell cell junction assembly GO:0007043 38 0.028
connective tissue development GO:0061448 3 0.027
regulation of multi organism process GO:0043900 131 0.027
amine metabolic process GO:0009308 12 0.027
male courtship behavior veined wing generated song production GO:0045433 20 0.027
immune response GO:0006955 246 0.027
germ cell migration GO:0008354 43 0.026
protein modification process GO:0036211 438 0.026
regionalization GO:0003002 416 0.026
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.026
organonitrogen compound biosynthetic process GO:1901566 117 0.026
olfactory behavior GO:0042048 97 0.026
single organism behavior GO:0044708 391 0.025
positive regulation of cell communication GO:0010647 250 0.025
response to external biotic stimulus GO:0043207 293 0.025
immune response regulating signaling pathway GO:0002764 2 0.025
response to abiotic stimulus GO:0009628 341 0.025
memory GO:0007613 94 0.025
regulation of localization GO:0032879 275 0.025
flight behavior GO:0007629 26 0.025
organic acid metabolic process GO:0006082 103 0.025
cell junction organization GO:0034330 57 0.025
covalent chromatin modification GO:0016569 106 0.025
catecholamine biosynthetic process GO:0042423 3 0.025
cellular ketone metabolic process GO:0042180 24 0.025
axis specification GO:0009798 167 0.025
multi multicellular organism process GO:0044706 123 0.025
sensory perception of smell GO:0007608 80 0.024
regulation of cell cycle process GO:0010564 181 0.024
negative regulation of multicellular organismal process GO:0051241 142 0.024
regulation of gene expression epigenetic GO:0040029 128 0.024
positive regulation of rna metabolic process GO:0051254 271 0.024
segmentation GO:0035282 207 0.023
response to light stimulus GO:0009416 124 0.023
cell junction assembly GO:0034329 42 0.023
catabolic process GO:0009056 409 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.023
tube morphogenesis GO:0035239 191 0.023
locomotor rhythm GO:0045475 56 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
gene silencing GO:0016458 138 0.022
respiratory system development GO:0060541 213 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
brain development GO:0007420 120 0.022
cuticle pigmentation GO:0048067 22 0.021
regulation of immune response GO:0050776 118 0.021
epithelial cell differentiation GO:0030855 322 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
response to oxygen containing compound GO:1901700 200 0.021
entrainment of circadian clock GO:0009649 16 0.021
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 7 0.021
negative regulation of rna metabolic process GO:0051253 251 0.020
spindle organization GO:0007051 253 0.020
appendage development GO:0048736 401 0.020
sensory organ morphogenesis GO:0090596 260 0.020
mating behavior GO:0007617 106 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
anterior posterior axis specification GO:0009948 109 0.020
response to radiation GO:0009314 155 0.020
limb development GO:0060173 1 0.020
transmembrane transport GO:0055085 139 0.020
open tracheal system development GO:0007424 204 0.020
dna metabolic process GO:0006259 227 0.020
cell death GO:0008219 279 0.020
wing disc morphogenesis GO:0007472 344 0.020
organelle fission GO:0048285 340 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
cell motility GO:0048870 251 0.019
positive regulation of defense response GO:0031349 59 0.019
protein localization GO:0008104 284 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
death GO:0016265 284 0.019
immune system process GO:0002376 347 0.019
camera type eye development GO:0043010 4 0.019
body morphogenesis GO:0010171 2 0.019
catechol containing compound biosynthetic process GO:0009713 3 0.019
cation transmembrane transport GO:0098655 88 0.019
behavioral response to ethanol GO:0048149 49 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
rna splicing via transesterification reactions GO:0000375 73 0.018
phagocytosis GO:0006909 215 0.018
cellular catabolic process GO:0044248 372 0.018
neuron recognition GO:0008038 101 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
kidney development GO:0001822 3 0.017
histone modification GO:0016570 106 0.017
cation transport GO:0006812 110 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
response to organophosphorus GO:0046683 2 0.017
positive regulation of cell motility GO:2000147 3 0.017
camera type eye morphogenesis GO:0048593 2 0.017
programmed cell death GO:0012501 257 0.017
response to alcohol GO:0097305 95 0.017
aromatic compound catabolic process GO:0019439 166 0.017
cellular protein modification process GO:0006464 438 0.017
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.017
negative regulation of apoptotic process GO:0043066 63 0.017
regulation of apoptotic process GO:0042981 130 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
multi organism behavior GO:0051705 175 0.016
cell migration GO:0016477 238 0.016
regulation of epithelial cell differentiation GO:0030856 4 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
digestive tract morphogenesis GO:0048546 127 0.016
response to gravity GO:0009629 26 0.016
dopamine biosynthetic process GO:0042416 3 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
regulation of locomotion GO:0040012 42 0.016
mrna metabolic process GO:0016071 124 0.016
tube development GO:0035295 244 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
proteolysis GO:0006508 192 0.016
store operated calcium entry GO:0002115 3 0.016
multi organism reproductive behavior GO:0044705 121 0.016
single organism biosynthetic process GO:0044711 206 0.016
tripartite regional subdivision GO:0007351 103 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
macromolecular complex assembly GO:0065003 256 0.016
regulation of response to wounding GO:1903034 19 0.015
tissue migration GO:0090130 155 0.015
circadian sleep wake cycle process GO:0022410 24 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
male mating behavior GO:0060179 70 0.015
developmental growth GO:0048589 280 0.015
establishment of localization in cell GO:0051649 402 0.015
mitotic nuclear division GO:0007067 213 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.015
actin filament based process GO:0030029 220 0.015
exocrine system development GO:0035272 162 0.015
single organism catabolic process GO:0044712 228 0.015
small molecule metabolic process GO:0044281 305 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
cell cycle checkpoint GO:0000075 95 0.015
cell division GO:0051301 248 0.014
purine containing compound metabolic process GO:0072521 155 0.014
regulation of cell differentiation GO:0045595 302 0.014
regulation of cell maturation GO:1903429 27 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
gravitaxis GO:0042332 26 0.014
oocyte construction GO:0007308 112 0.014
positive regulation of cell death GO:0010942 69 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.014
embryonic pattern specification GO:0009880 174 0.014
circulatory system process GO:0003013 37 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
regulation of reproductive process GO:2000241 54 0.014
peptidyl threonine phosphorylation GO:0018107 2 0.014
cellular protein localization GO:0034613 160 0.014
regulation of blood circulation GO:1903522 21 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
anatomical structure homeostasis GO:0060249 97 0.014
rna processing GO:0006396 147 0.014
response to lipopolysaccharide GO:0032496 4 0.014
cellular response to biotic stimulus GO:0071216 4 0.014
central nervous system development GO:0007417 201 0.014
regulation of cell death GO:0010941 173 0.014
regulation of cellular localization GO:0060341 136 0.014
cell recognition GO:0008037 102 0.014
regulation of defense response GO:0031347 102 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
heterocycle catabolic process GO:0046700 166 0.014
defense response to other organism GO:0098542 225 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
humoral immune response GO:0006959 117 0.014
organelle assembly GO:0070925 198 0.014
mitotic cell cycle phase transition GO:0044772 138 0.013
positive regulation of immune response GO:0050778 63 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
lateral inhibition GO:0046331 206 0.013
chromosome segregation GO:0007059 157 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
septate junction assembly GO:0019991 26 0.013
mitotic spindle organization GO:0007052 220 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
embryonic axis specification GO:0000578 107 0.013
single organism cellular localization GO:1902580 180 0.013
male gamete generation GO:0048232 201 0.013
response to nitrogen compound GO:1901698 90 0.013
post embryonic appendage morphogenesis GO:0035120 385 0.013
axon development GO:0061564 297 0.013
endomembrane system organization GO:0010256 119 0.013
positive regulation of catabolic process GO:0009896 105 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
male courtship behavior veined wing vibration GO:0016545 21 0.013
photoreceptor cell fate commitment GO:0046552 41 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
mating GO:0007618 120 0.013
response to bacterium GO:0009617 198 0.013
appendage morphogenesis GO:0035107 397 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
signal release GO:0023061 49 0.013
cognition GO:0050890 141 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
meiotic cell cycle process GO:1903046 132 0.013
transmission of nerve impulse GO:0019226 12 0.012
regulation of catabolic process GO:0009894 170 0.012
regulation of cell development GO:0060284 215 0.012
regulation of cellular component movement GO:0051270 42 0.012
neuromuscular synaptic transmission GO:0007274 67 0.012
hindgut morphogenesis GO:0007442 58 0.012
reproductive behavior GO:0019098 122 0.012
gland morphogenesis GO:0022612 145 0.012
telencephalon development GO:0021537 2 0.012
leg disc development GO:0035218 92 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
taxis GO:0042330 304 0.012
regulation of mapk cascade GO:0043408 92 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
response to hypoxia GO:0001666 53 0.012
positive regulation of cell migration GO:0030335 2 0.012
organelle fusion GO:0048284 46 0.012
limb morphogenesis GO:0035108 1 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
courtship behavior GO:0007619 68 0.012
synaptic target recognition GO:0008039 45 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
apoptotic process GO:0006915 159 0.012
response to decreased oxygen levels GO:0036293 58 0.012
actin cytoskeleton organization GO:0030036 206 0.012
kidney epithelium development GO:0072073 3 0.012
response to heat GO:0009408 63 0.012
cell aging GO:0007569 2 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
gastrulation with mouth forming first GO:0001703 36 0.012
nephron tubule development GO:0072080 3 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
heart contraction GO:0060047 26 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
cell type specific apoptotic process GO:0097285 38 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
mrna processing GO:0006397 104 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
pigmentation GO:0043473 75 0.011
salivary gland morphogenesis GO:0007435 145 0.011
gene silencing by rna GO:0031047 57 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
negative regulation of immune system process GO:0002683 50 0.011
regulation of response to oxidative stress GO:1902882 4 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
steroid catabolic process GO:0006706 1 0.011
myotube cell development GO:0014904 3 0.011
digestive tract development GO:0048565 149 0.011
maternal determination of anterior posterior axis embryo GO:0008358 74 0.011
oocyte anterior posterior axis specification GO:0007314 72 0.011
actin filament based movement GO:0030048 26 0.011
tissue morphogenesis GO:0048729 297 0.011
regulation of tube size GO:0035150 46 0.011
ameboidal type cell migration GO:0001667 151 0.011
positive regulation of multi organism process GO:0043902 40 0.011
ventral furrow formation GO:0007370 17 0.011
regulation of system process GO:0044057 36 0.011
ethanolamine containing compound metabolic process GO:0042439 4 0.011
peptidyl threonine modification GO:0018210 3 0.011
eye morphogenesis GO:0048592 260 0.011
alternative mrna splicing via spliceosome GO:0000380 60 0.011
innate immune response GO:0045087 144 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
rna localization GO:0006403 115 0.011
gastrulation involving germ band extension GO:0010004 36 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
chromosome separation GO:0051304 42 0.011
nucleoside phosphate biosynthetic process GO:1901293 34 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
male courtship behavior GO:0008049 63 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
regulation of synaptic transmission GO:0050804 69 0.010
outflow tract morphogenesis GO:0003151 4 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
rna splicing GO:0008380 83 0.010
response to ethanol GO:0045471 59 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
negative regulation of epithelial cell proliferation GO:0050680 4 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010
chloride transport GO:0006821 10 0.010
kidney morphogenesis GO:0060993 3 0.010
anion transport GO:0006820 41 0.010
ras protein signal transduction GO:0007265 88 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
protein complex assembly GO:0006461 200 0.010
cell adhesion GO:0007155 136 0.010
gland development GO:0048732 191 0.010
neuropeptide signaling pathway GO:0007218 45 0.010
secretion by cell GO:0032940 101 0.010
mrna splicing via spliceosome GO:0000398 73 0.010
glutamine family amino acid catabolic process GO:0009065 3 0.010
modification dependent protein catabolic process GO:0019941 78 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
embryonic morphogenesis GO:0048598 206 0.010
imaginal disc pattern formation GO:0007447 91 0.010
negative regulation of response to oxidative stress GO:1902883 1 0.010
protein ubiquitination GO:0016567 70 0.010

VGAT disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.018
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
acquired metabolic disease DOID:0060158 0 0.013
inherited metabolic disorder DOID:655 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
artery disease DOID:0050828 0 0.012
vascular disease DOID:178 0 0.012
cardiovascular system disease DOID:1287 0 0.012
musculoskeletal system disease DOID:17 0 0.010